Danio rerio

0 known processes

si:dkey-42o15.2

si:dkey-42o15.2

(Aliases: im:7155919,im:7139164,lrig2)

si:dkey-42o15.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.074
aging GO:0007568 2 0.051
cellular protein catabolic process GO:0044257 4 0.050
regulation of multicellular organismal process GO:0051239 277 0.048
stem cell maintenance GO:0019827 4 0.048
maintenance of location GO:0051235 4 0.047
sensory organ development GO:0007423 393 0.044
nitrogen compound metabolic process GO:0006807 319 0.044
positive regulation of transport GO:0051050 2 0.042
establishment of protein localization to organelle GO:0072594 4 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.041
cellular macromolecule metabolic process GO:0044260 391 0.040
negative regulation of biological process GO:0048519 304 0.040
modification dependent protein catabolic process GO:0019941 3 0.040
meiotic nuclear division GO:0007126 4 0.040
regulation of establishment of protein localization GO:0070201 4 0.039
lipid storage GO:0019915 1 0.039
signal transduction GO:0007165 455 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
response to chemical GO:0042221 320 0.035
nucleic acid metabolic process GO:0090304 244 0.035
aromatic compound biosynthetic process GO:0019438 217 0.035
organelle organization GO:0006996 227 0.035
modification dependent macromolecule catabolic process GO:0043632 3 0.035
regulation of mrna processing GO:0050684 3 0.035
regulation of stem cell proliferation GO:0072091 2 0.034
ubiquitin dependent protein catabolic process GO:0006511 3 0.034
cellular biosynthetic process GO:0044249 286 0.034
gene expression GO:0010467 252 0.034
positive regulation of cell cycle GO:0045787 3 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.033
multicellular organism growth GO:0035264 4 0.033
amine metabolic process GO:0009308 2 0.033
cellular nitrogen compound biosynthetic process GO:0044271 218 0.033
biosynthetic process GO:0009058 294 0.033
regulation of protein transport GO:0051223 3 0.032
cellular amine metabolic process GO:0044106 2 0.032
organic substance biosynthetic process GO:1901576 289 0.032
regulation of cellular metabolic process GO:0031323 320 0.032
protein localization to nucleus GO:0034504 3 0.032
nucleocytoplasmic transport GO:0006913 4 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
cell surface receptor signaling pathway GO:0007166 325 0.031
transcription dna templated GO:0006351 181 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
phagocytosis GO:0006909 3 0.031
negative regulation of cellular process GO:0048523 283 0.031
regulation of biological quality GO:0065008 263 0.030
protein acetylation GO:0006473 2 0.030
regulation of cytokine production GO:0001817 3 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
protein targeting to nucleus GO:0044744 3 0.030
nuclear transport GO:0051169 4 0.029
regulation of developmental process GO:0050793 247 0.029
heterocycle metabolic process GO:0046483 290 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
regulation of primary metabolic process GO:0080090 311 0.028
rna metabolic process GO:0016070 219 0.028
protein import GO:0017038 3 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
regulation of metabolic process GO:0019222 359 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
mononuclear cell proliferation GO:0032943 1 0.027
internal protein amino acid acetylation GO:0006475 2 0.026
regulation of signaling GO:0023051 235 0.026
stem cell proliferation GO:0072089 4 0.026
proteasomal protein catabolic process GO:0010498 2 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
regulation of response to stimulus GO:0048583 269 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
regulation of protein catabolic process GO:0042176 1 0.026
regulation of biosynthetic process GO:0009889 250 0.026
positive regulation of catabolic process GO:0009896 4 0.026
regulation of intracellular protein transport GO:0033157 3 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
single organism nuclear import GO:1902593 3 0.025
vasculature development GO:0001944 278 0.025
regulation of gene expression GO:0010468 265 0.025
regulation of signal transduction GO:0009966 225 0.025
regulation of cell communication GO:0010646 232 0.025
cell cycle g1 s phase transition GO:0044843 1 0.025
nuclear import GO:0051170 3 0.024
regulation of neural precursor cell proliferation GO:2000177 3 0.024
regulation of cell activation GO:0050865 1 0.024
protein acylation GO:0043543 3 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
regionalization GO:0003002 274 0.024
regulation of meiotic cell cycle GO:0051445 1 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
internal peptidyl lysine acetylation GO:0018393 2 0.023
blood vessel morphogenesis GO:0048514 216 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
cell morphogenesis GO:0000902 289 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
single organism metabolic process GO:0044710 217 0.023
establishment of localization GO:0051234 244 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
blood vessel development GO:0001568 246 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
neuron differentiation GO:0030182 353 0.023
regulation of binding GO:0051098 3 0.022
leukocyte proliferation GO:0070661 1 0.022
rna biosynthetic process GO:0032774 181 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
regulation of rna metabolic process GO:0051252 224 0.022
single organism organelle organization GO:1902589 199 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
peptidyl lysine acetylation GO:0018394 2 0.022
nucleic acid templated transcription GO:0097659 181 0.021
female sex differentiation GO:0046660 4 0.021
cell projection morphogenesis GO:0048858 244 0.021
positive regulation of biological process GO:0048518 253 0.021
response to drug GO:0042493 3 0.021
immune system process GO:0002376 241 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cellular ketone metabolic process GO:0042180 11 0.021
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
central nervous system development GO:0007417 387 0.021
protein import into nucleus GO:0006606 3 0.021
regulation of nucleic acid templated transcription GO:1903506 213 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
positive regulation of cellular process GO:0048522 201 0.020
positive regulation of stress activated mapk cascade GO:0032874 3 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
cellular protein metabolic process GO:0044267 129 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
cellular component biogenesis GO:0044085 178 0.020
positive regulation of cell activation GO:0050867 1 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
negative regulation of ras protein signal transduction GO:0046580 1 0.020
positive regulation of secretion GO:0051047 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
protein stabilization GO:0050821 2 0.020
response to external stimulus GO:0009605 264 0.019
somatic stem cell maintenance GO:0035019 1 0.019
gtp catabolic process GO:0006184 2 0.019
cellular response to starvation GO:0009267 1 0.019
positive regulation of cytokine production GO:0001819 2 0.019
response to stress GO:0006950 263 0.019
wnt signaling pathway GO:0016055 80 0.019
cellular response to external stimulus GO:0071496 2 0.019
response to carbohydrate GO:0009743 3 0.019
regulation of transcription dna templated GO:0006355 213 0.019
generation of neurons GO:0048699 385 0.019
response to organic substance GO:0010033 153 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
lymphocyte proliferation GO:0046651 1 0.019
transport GO:0006810 220 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
regulation of protein targeting GO:1903533 2 0.018
peptidyl threonine phosphorylation GO:0018107 1 0.018
negative regulation of catabolic process GO:0009895 3 0.018
locomotor rhythm GO:0045475 3 0.018
protein metabolic process GO:0019538 183 0.018
primary neural tube formation GO:0014020 1 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
female gonad development GO:0008585 4 0.018
tube closure GO:0060606 1 0.018
protein polyubiquitination GO:0000209 4 0.018
response to topologically incorrect protein GO:0035966 2 0.018
cellular response to nutrient levels GO:0031669 2 0.018
tube morphogenesis GO:0035239 349 0.017
positive regulation of jnk cascade GO:0046330 3 0.017
alternative mrna splicing via spliceosome GO:0000380 1 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
heart development GO:0007507 313 0.017
cellular component morphogenesis GO:0032989 336 0.017
mitochondrion organization GO:0007005 4 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
adherens junction organization GO:0034332 4 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
cell part morphogenesis GO:0032990 246 0.017
cellular component disassembly GO:0022411 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
cell substrate adhesion GO:0031589 4 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
immune system development GO:0002520 191 0.017
growth GO:0040007 174 0.017
cell projection organization GO:0030030 284 0.017
cell matrix adhesion GO:0007160 4 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
microtubule organizing center organization GO:0031023 1 0.017
response to monosaccharide GO:0034284 3 0.017
lamellipodium assembly GO:0030032 1 0.016
protein secretion GO:0009306 1 0.016
compound eye development GO:0048749 2 0.016
regulation of cell shape GO:0008360 1 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
gtp metabolic process GO:0046039 4 0.016
regulation of protein complex assembly GO:0043254 3 0.016
regulation of cell differentiation GO:0045595 142 0.016
head development GO:0060322 303 0.016
negative regulation of gene expression GO:0010629 65 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
locomotion GO:0040011 313 0.016
hemopoiesis GO:0030097 183 0.016
cellular amide metabolic process GO:0043603 4 0.016
protein localization to plasma membrane GO:0072659 1 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.016
angiogenesis GO:0001525 158 0.016
oxoacid metabolic process GO:0043436 31 0.016
cytokinesis GO:0000910 3 0.016
positive regulation of immune effector process GO:0002699 3 0.016
cellular component movement GO:0006928 335 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.015
determination of bilateral symmetry GO:0009855 204 0.015
regulation of inflammatory response GO:0050727 2 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
peptidyl serine modification GO:0018209 2 0.015
endosomal transport GO:0016197 2 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
tissue remodeling GO:0048771 4 0.015
eye development GO:0001654 277 0.015
cellular component assembly GO:0022607 170 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
regulation of synapse assembly GO:0051963 3 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
response to hexose GO:0009746 3 0.015
cell migration GO:0016477 237 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.014
autophagy GO:0006914 4 0.014
rna localization GO:0006403 4 0.014
digestive tract development GO:0048565 265 0.014
death GO:0016265 121 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
cellular response to organic substance GO:0071310 105 0.014
brain development GO:0007420 293 0.014
response to uv GO:0009411 3 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
embryonic organ development GO:0048568 381 0.014
negative regulation of cytokine production GO:0001818 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
response to glucose GO:0009749 3 0.014
small molecule metabolic process GO:0044281 77 0.014
macromolecule modification GO:0043412 111 0.014
organic acid metabolic process GO:0006082 31 0.014
single organism transport GO:0044765 206 0.014
cellular response to topologically incorrect protein GO:0035967 2 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
positive regulation of notch signaling pathway GO:0045747 3 0.014
secondary metabolic process GO:0019748 3 0.014
cellular protein modification process GO:0006464 100 0.014
regulation of response to biotic stimulus GO:0002831 2 0.014
meiotic cell cycle process GO:1903046 3 0.013
phagocytosis engulfment GO:0006911 1 0.013
anterior posterior pattern specification GO:0009952 152 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
regulation of autophagy GO:0010506 3 0.013
macroautophagy GO:0016236 1 0.013
regulation of wnt signaling pathway GO:0030111 53 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
centrosome organization GO:0051297 1 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
gastrulation GO:0007369 208 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
membrane fusion GO:0061025 2 0.013
neuroblast proliferation GO:0007405 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
glucose homeostasis GO:0042593 1 0.013
positive regulation of metabolic process GO:0009893 108 0.013
nephron tubule morphogenesis GO:0072078 1 0.013
sequestering of metal ion GO:0051238 3 0.013
neuron development GO:0048666 262 0.013
homeostatic process GO:0042592 142 0.013
single organism localization GO:1902578 225 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
single organism membrane fusion GO:0044801 2 0.013
digestive tract morphogenesis GO:0048546 231 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
germ line stem cell maintenance GO:0030718 2 0.013
nuclear export GO:0051168 1 0.013
digestive system development GO:0055123 289 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
spermatid development GO:0007286 2 0.012
developmental growth GO:0048589 166 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
response to wounding GO:0009611 116 0.012
response to other organism GO:0051707 97 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
positive regulation of histone modification GO:0031058 1 0.012
response to nutrient GO:0007584 3 0.012
negative regulation of secretion by cell GO:1903531 2 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
protein modification process GO:0036211 100 0.012
cognition GO:0050890 1 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
membrane invagination GO:0010324 1 0.012
nucleic acid transport GO:0050657 2 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
negative regulation of signaling GO:0023057 96 0.012
segmentation GO:0035282 97 0.012
apoptotic process GO:0006915 116 0.012
macromolecular complex disassembly GO:0032984 1 0.012
camera type eye development GO:0043010 222 0.012
cell motility GO:0048870 244 0.012
negative regulation of secretion GO:0051048 2 0.012
organelle fusion GO:0048284 3 0.012
regulation of synapse organization GO:0050807 3 0.012
peptide transport GO:0015833 1 0.012
peptidyl threonine modification GO:0018210 1 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
double strand break repair GO:0006302 3 0.012
stem cell division GO:0017145 1 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of cellular component organization GO:0051128 86 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
negative regulation of metabolic process GO:0009892 86 0.012
negative regulation of signal transduction GO:0009968 94 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
lipid homeostasis GO:0055088 3 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
negative regulation of defense response GO:0031348 2 0.011
multi organism process GO:0051704 134 0.011
phosphorus metabolic process GO:0006793 109 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
lateral inhibition GO:0046331 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
outflow tract morphogenesis GO:0003151 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of dna replication GO:0006275 3 0.011
hormone secretion GO:0046879 2 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
negative regulation of nuclear division GO:0051784 3 0.011
adult behavior GO:0030534 2 0.011
negative regulation of developmental process GO:0051093 65 0.011
chemosensory behavior GO:0007635 1 0.011
system process GO:0003008 185 0.011
positive regulation of translation GO:0045727 1 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of metal ion transport GO:0010959 4 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
b cell activation GO:0042113 2 0.011
telomere organization GO:0032200 1 0.011
exocytosis GO:0006887 1 0.011
protein complex disassembly GO:0043241 1 0.011
wound healing GO:0042060 90 0.011
retina development in camera type eye GO:0060041 146 0.011
telomere maintenance GO:0000723 1 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
response to biotic stimulus GO:0009607 97 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
synaptic target recognition GO:0008039 1 0.011
rna 3 end processing GO:0031123 2 0.011
programmed cell death GO:0012501 119 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
meiosis i GO:0007127 1 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
membrane lipid biosynthetic process GO:0046467 2 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
golgi vesicle transport GO:0048193 3 0.011
neuron projection morphogenesis GO:0048812 161 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
negative regulation of cell communication GO:0010648 96 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
protein polymerization GO:0051258 4 0.011
determination of left right symmetry GO:0007368 179 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
regulation of localization GO:0032879 104 0.010
dna templated transcription elongation GO:0006354 3 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
chordate embryonic development GO:0043009 271 0.010
liver development GO:0001889 96 0.010
response to unfolded protein GO:0006986 2 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
protein homooligomerization GO:0051260 3 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
hormone transport GO:0009914 2 0.010
response to external biotic stimulus GO:0043207 97 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
urogenital system development GO:0001655 97 0.010
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.010
myeloid cell differentiation GO:0030099 86 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
atp catabolic process GO:0006200 4 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010

si:dkey-42o15.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
musculoskeletal system disease DOID:17 0 0.015
muscular disease DOID:0080000 0 0.011