Danio rerio

0 known processes

atl2

atlastin GTPase 2

(Aliases: wu:fc06e01,arl6ip2,fc06e01,wu:fv60d03)

atl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 4 0.102
phagocytosis GO:0006909 3 0.078
larval development GO:0002164 2 0.075
ubiquitin dependent protein catabolic process GO:0006511 3 0.067
nitrogen compound metabolic process GO:0006807 319 0.066
positive regulation of cellular catabolic process GO:0031331 3 0.062
cytokinesis GO:0000910 3 0.061
organelle fusion GO:0048284 3 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.056
guanosine containing compound catabolic process GO:1901069 2 0.056
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.056
positive regulation of catabolic process GO:0009896 4 0.055
cellular nitrogen compound metabolic process GO:0034641 290 0.054
carboxylic acid catabolic process GO:0046395 3 0.053
guanosine containing compound metabolic process GO:1901068 4 0.049
modification dependent protein catabolic process GO:0019941 3 0.048
aging GO:0007568 2 0.046
glucose import GO:0046323 2 0.044
proteasomal protein catabolic process GO:0010498 2 0.044
single organism metabolic process GO:0044710 217 0.042
gtp catabolic process GO:0006184 2 0.042
cellular component assembly GO:0022607 170 0.041
apoptotic process GO:0006915 116 0.041
gtp metabolic process GO:0046039 4 0.039
regulation of cellular metabolic process GO:0031323 320 0.038
small molecule catabolic process GO:0044282 3 0.038
transport GO:0006810 220 0.037
membrane fusion GO:0061025 2 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.036
atp catabolic process GO:0006200 4 0.034
lipid catabolic process GO:0016042 4 0.034
organic acid catabolic process GO:0016054 3 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
single organism membrane fusion GO:0044801 2 0.033
regulation of gene expression GO:0010468 265 0.033
protein stabilization GO:0050821 2 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
cellular macromolecule metabolic process GO:0044260 391 0.032
cell surface receptor signaling pathway GO:0007166 325 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
heterocycle metabolic process GO:0046483 290 0.031
regulation of nucleotide catabolic process GO:0030811 2 0.030
death GO:0016265 121 0.030
small molecule metabolic process GO:0044281 77 0.030
response to chemical GO:0042221 320 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.029
positive regulation of transport GO:0051050 2 0.028
regulation of apoptotic process GO:0042981 98 0.028
regulation of binding GO:0051098 3 0.028
nucleic acid metabolic process GO:0090304 244 0.027
programmed cell death GO:0012501 119 0.027
single organism localization GO:1902578 225 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
multicellular organism growth GO:0035264 4 0.026
cellular component biogenesis GO:0044085 178 0.026
digestive system development GO:0055123 289 0.025
regulation of protein transport GO:0051223 3 0.025
rna biosynthetic process GO:0032774 181 0.025
autophagy GO:0006914 4 0.025
embryonic organ development GO:0048568 381 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
single organism transport GO:0044765 206 0.024
response to stress GO:0006950 263 0.024
fatty acid catabolic process GO:0009062 1 0.024
rna metabolic process GO:0016070 219 0.024
protein targeting to nucleus GO:0044744 3 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
protein polyubiquitination GO:0000209 4 0.024
oxoacid metabolic process GO:0043436 31 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.024
cell part morphogenesis GO:0032990 246 0.024
protein metabolic process GO:0019538 183 0.024
organic acid metabolic process GO:0006082 31 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
regulation of gtp catabolic process GO:0033124 2 0.023
leukocyte proliferation GO:0070661 1 0.023
response to nutrient GO:0007584 3 0.022
transcription dna templated GO:0006351 181 0.022
cytoskeleton dependent cytokinesis GO:0061640 3 0.022
protein localization to nucleus GO:0034504 3 0.022
neuron differentiation GO:0030182 353 0.022
single organism organelle organization GO:1902589 199 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
brain development GO:0007420 293 0.022
regulation of programmed cell death GO:0043067 101 0.021
organic substance biosynthetic process GO:1901576 289 0.021
membrane lipid biosynthetic process GO:0046467 2 0.021
cellular response to external stimulus GO:0071496 2 0.021
heart development GO:0007507 313 0.021
positive regulation of gtpase activity GO:0043547 1 0.021
endosomal transport GO:0016197 2 0.021
stem cell proliferation GO:0072089 4 0.021
phosphorus metabolic process GO:0006793 109 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
cellular protein modification process GO:0006464 100 0.021
protein localization to plasma membrane GO:0072659 1 0.021
monocarboxylic acid catabolic process GO:0072329 3 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
negative regulation of secretion GO:0051048 2 0.021
biosynthetic process GO:0009058 294 0.021
response to external stimulus GO:0009605 264 0.021
meiotic nuclear division GO:0007126 4 0.020
protein modification process GO:0036211 100 0.020
head development GO:0060322 303 0.020
female sex differentiation GO:0046660 4 0.020
positive regulation of gtp catabolic process GO:0033126 1 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
meiotic cell cycle process GO:1903046 3 0.020
regulation of protein catabolic process GO:0042176 1 0.020
cellular lipid catabolic process GO:0044242 3 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
regulation of gtpase activity GO:0043087 2 0.020
positive regulation of map kinase activity GO:0043406 3 0.020
regulation of hormone secretion GO:0046883 2 0.020
regulation of cell death GO:0010941 103 0.020
positive regulation of biological process GO:0048518 253 0.019
positive regulation of stress activated mapk cascade GO:0032874 3 0.019
nuclear transport GO:0051169 4 0.019
cell morphogenesis GO:0000902 289 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
regulation of primary metabolic process GO:0080090 311 0.019
positive regulation of secretion GO:0051047 1 0.019
hormone secretion GO:0046879 2 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
somatic muscle development GO:0007525 4 0.019
macromolecule modification GO:0043412 111 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
response to drug GO:0042493 3 0.019
spindle assembly GO:0051225 2 0.019
negative regulation of signal transduction GO:0009968 94 0.019
regulation of rna metabolic process GO:0051252 224 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
generation of neurons GO:0048699 385 0.018
response to carbohydrate GO:0009743 3 0.018
response to hexose GO:0009746 3 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
cellular biosynthetic process GO:0044249 286 0.018
negative regulation of nuclear division GO:0051784 3 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
nucleic acid templated transcription GO:0097659 181 0.018
compound eye development GO:0048749 2 0.018
sphingolipid biosynthetic process GO:0030148 2 0.018
positive regulation of metabolic process GO:0009893 108 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
liver development GO:0001889 96 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
negative regulation of intracellular transport GO:0032387 3 0.018
regulation of synapse organization GO:0050807 3 0.017
cell projection morphogenesis GO:0048858 244 0.017
regulation of cell activation GO:0050865 1 0.017
establishment of localization GO:0051234 244 0.017
cell death GO:0008219 121 0.017
regulation of biosynthetic process GO:0009889 250 0.017
maintenance of location GO:0051235 4 0.017
response to glucose GO:0009749 3 0.017
regulation of synapse assembly GO:0051963 3 0.017
adult behavior GO:0030534 2 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.016
regulation of transcription dna templated GO:0006355 213 0.016
peptide transport GO:0015833 1 0.016
lipid oxidation GO:0034440 1 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
ovulation cycle GO:0042698 2 0.016
response to glucocorticoid GO:0051384 1 0.016
membrane organization GO:0061024 21 0.016
central nervous system development GO:0007417 387 0.016
cellular response to nutrient levels GO:0031669 2 0.016
tube morphogenesis GO:0035239 349 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
gland development GO:0048732 143 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
organic substance catabolic process GO:1901575 28 0.016
negative regulation of response to stimulus GO:0048585 104 0.015
lipid storage GO:0019915 1 0.015
cellular localization GO:0051641 97 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
response to corticosteroid GO:0031960 1 0.015
regulation of metabolic process GO:0019222 359 0.015
regulation of response to stimulus GO:0048583 269 0.015
carbohydrate homeostasis GO:0033500 1 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
mitotic cytokinesis GO:0000281 3 0.015
determination of bilateral symmetry GO:0009855 204 0.015
tube closure GO:0060606 1 0.015
protein import GO:0017038 3 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
cellular component morphogenesis GO:0032989 336 0.015
signal transduction GO:0007165 455 0.015
regulation of protein complex assembly GO:0043254 3 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
cell substrate adhesion GO:0031589 4 0.015
cellular response to oxygen levels GO:0071453 1 0.015
nitric oxide metabolic process GO:0046209 2 0.015
cell projection organization GO:0030030 284 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
spermatid differentiation GO:0048515 2 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
single organism nuclear import GO:1902593 3 0.014
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
cellular protein metabolic process GO:0044267 129 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
meiotic chromosome segregation GO:0045132 3 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
negative regulation of defense response GO:0031348 2 0.014
regulation of cytokine production GO:0001817 3 0.014
locomotion GO:0040011 313 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
cellular response to hypoxia GO:0071456 1 0.014
negative regulation of signaling GO:0023057 96 0.014
negative regulation of kinase activity GO:0033673 4 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
regulation of cytokine mediated signaling pathway GO:0001959 3 0.014
protein secretion GO:0009306 1 0.014
mononuclear cell proliferation GO:0032943 1 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
cellular component disassembly GO:0022411 1 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
hormone transport GO:0009914 2 0.014
myeloid cell differentiation GO:0030099 86 0.014
cellular catabolic process GO:0044248 27 0.014
mitochondrion organization GO:0007005 4 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
regulation of protein binding GO:0043393 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
determination of left right symmetry GO:0007368 179 0.013
adherens junction organization GO:0034332 4 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
protein dephosphorylation GO:0006470 3 0.013
single fertilization GO:0007338 3 0.013
macroautophagy GO:0016236 1 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
hepaticobiliary system development GO:0061008 98 0.013
cellular amine metabolic process GO:0044106 2 0.013
response to hypoxia GO:0001666 25 0.013
response to abiotic stimulus GO:0009628 122 0.013
zymogen activation GO:0031638 3 0.013
homeostatic process GO:0042592 142 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
amine metabolic process GO:0009308 2 0.013
primary neural tube formation GO:0014020 1 0.013
response to organic substance GO:0010033 153 0.013
regulation of mrna processing GO:0050684 3 0.013
mitochondrial transport GO:0006839 2 0.013
positive regulation of cellular process GO:0048522 201 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
immune system development GO:0002520 191 0.013
positive regulation of ras protein signal transduction GO:0046579 1 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
regulation of glucose transport GO:0010827 1 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
nuclear import GO:0051170 3 0.013
regulation of cell communication GO:0010646 232 0.013
secondary metabolic process GO:0019748 3 0.012
regulation of organelle assembly GO:1902115 4 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
developmental programmed cell death GO:0010623 4 0.012
nuclear export GO:0051168 1 0.012
eye development GO:0001654 277 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
stem cell maintenance GO:0019827 4 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
cellular response to starvation GO:0009267 1 0.012
specification of symmetry GO:0009799 204 0.012
stem cell division GO:0017145 1 0.012
axonogenesis GO:0007409 152 0.012
digestive tract development GO:0048565 265 0.012
cellular component movement GO:0006928 335 0.012
response to other organism GO:0051707 97 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
activation of mapk activity GO:0000187 3 0.012
multi organism cellular process GO:0044764 2 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
cognition GO:0050890 1 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
catabolic process GO:0009056 32 0.012
regulation of glucose import GO:0046324 1 0.012
response to monosaccharide GO:0034284 3 0.012
negative regulation of cellular process GO:0048523 283 0.012
protein homooligomerization GO:0051260 3 0.012
centrosome cycle GO:0007098 1 0.012
gastrulation GO:0007369 208 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
negative regulation of biological process GO:0048519 304 0.012
spermatid development GO:0007286 2 0.012
cell aging GO:0007569 2 0.012
convergent extension GO:0060026 118 0.012
phagocytosis engulfment GO:0006911 1 0.012
toll like receptor signaling pathway GO:0002224 4 0.012
fatty acid oxidation GO:0019395 1 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
cellular ketone metabolic process GO:0042180 11 0.011
establishment of localization in cell GO:0051649 77 0.011
negative regulation of protein transport GO:0051224 3 0.011
response to endogenous stimulus GO:0009719 83 0.011
dicarboxylic acid metabolic process GO:0043648 1 0.011
gene expression GO:0010467 252 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
peptidyl serine modification GO:0018209 2 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
immune system process GO:0002376 241 0.011
fertilization GO:0009566 3 0.011
b cell activation GO:0042113 2 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
oxidation reduction process GO:0055114 41 0.011
tissue remodeling GO:0048771 4 0.011
regulation of cellular component organization GO:0051128 86 0.011
positive regulation of jun kinase activity GO:0043507 2 0.011
negative regulation of immune response GO:0050777 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
sensory organ development GO:0007423 393 0.011
regulation of organ growth GO:0046620 3 0.011
meiosis i GO:0007127 1 0.011
lipid metabolic process GO:0006629 52 0.011
sequestering of metal ion GO:0051238 3 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
regulation of protein targeting GO:1903533 2 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
response to external biotic stimulus GO:0043207 97 0.011
cellular respiration GO:0045333 3 0.011
positive regulation of cell cycle GO:0045787 3 0.011
taxis GO:0042330 109 0.011
protein import into nucleus GO:0006606 3 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
ras protein signal transduction GO:0007265 7 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
vasculature development GO:0001944 278 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
nitric oxide biosynthetic process GO:0006809 2 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
proteolysis GO:0006508 38 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
response to biotic stimulus GO:0009607 97 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
synaptic vesicle localization GO:0097479 1 0.010
neuron development GO:0048666 262 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
centrosome organization GO:0051297 1 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
macromolecular complex disassembly GO:0032984 1 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
viral process GO:0016032 1 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
regulation of signaling GO:0023051 235 0.010
interspecies interaction between organisms GO:0044419 4 0.010
digestive tract morphogenesis GO:0048546 231 0.010
negative regulation of cell communication GO:0010648 96 0.010
lateral inhibition GO:0046331 1 0.010
antimicrobial humoral response GO:0019730 2 0.010
positive regulation of jnk cascade GO:0046330 3 0.010

atl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
disease of metabolism DOID:0014667 0 0.034
inherited metabolic disorder DOID:655 0 0.022
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.015
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
muscular disease DOID:0080000 0 0.012
organ system cancer DOID:0050686 0 0.011