Danio rerio

0 known processes

gnat1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

(Aliases: wu:fk56e06)

gnat1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of light stimulus GO:0009583 12 0.941
Zebrafish Mouse
phototransduction visible light GO:0007603 2 0.873
light absorption GO:0016037 2 0.850
absorption of visible light GO:0016038 2 0.820
g protein coupled receptor signaling pathway GO:0007186 74 0.676
Yeast Mouse Fly
cellular response to radiation GO:0071478 4 0.621
detection of external stimulus GO:0009581 24 0.582
Zebrafish Mouse
detection of stimulus GO:0051606 29 0.579
Zebrafish Mouse
rhodopsin mediated signaling pathway GO:0016056 1 0.572
eye development GO:0001654 277 0.528
Mouse
negative regulation of cell cell adhesion mediated by cadherin GO:2000048 2 0.512
Zebrafish
sensory organ development GO:0007423 393 0.511
Mouse
detection of abiotic stimulus GO:0009582 24 0.478
Zebrafish Mouse
retina development in camera type eye GO:0060041 146 0.457
Mouse
response to light stimulus GO:0009416 46 0.438
Zebrafish Mouse
response to abiotic stimulus GO:0009628 122 0.424
Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.421
Mouse
vitamin a metabolic process GO:0006776 1 0.407
detection of visible light GO:0009584 12 0.392
Zebrafish Mouse
photoperiodism GO:0009648 11 0.385
cellular nitrogen compound metabolic process GO:0034641 290 0.362
Yeast Mouse
phototransduction GO:0007602 2 0.331
Mouse
regulation of sequestering of calcium ion GO:0051282 4 0.321
signal transduction GO:0007165 455 0.317
Yeast Zebrafish Mouse Fly
light induced release of internally sequestered calcium ion GO:0008377 1 0.297
cellular response to light stimulus GO:0071482 4 0.266
photoreceptor cell development GO:0042461 40 0.244
Mouse
photoreceptor cell differentiation GO:0046530 55 0.238
Mouse
positive regulation of map kinase activity GO:0043406 3 0.172
nitrogen compound metabolic process GO:0006807 319 0.171
Yeast Mouse
cgmp metabolic process GO:0046068 7 0.170
response to radiation GO:0009314 51 0.161
Zebrafish Mouse
homeostatic process GO:0042592 142 0.147
camera type eye development GO:0043010 222 0.140
Mouse
regulation of cellular metabolic process GO:0031323 320 0.127
Yeast
heterocycle metabolic process GO:0046483 290 0.126
Yeast Mouse
negative regulation of sequestering of calcium ion GO:0051283 4 0.125
circadian sleep wake cycle GO:0042745 2 0.119
sequestering of calcium ion GO:0051208 3 0.111
small molecule metabolic process GO:0044281 77 0.110
Yeast Mouse
ribose phosphate metabolic process GO:0019693 27 0.105
Yeast Mouse
gastrulation GO:0007369 208 0.104
Zebrafish
cortical cytoskeleton organization GO:0030865 1 0.103
Fly
retina morphogenesis in camera type eye GO:0060042 79 0.098
camera type eye morphogenesis GO:0048593 108 0.098
cell fate commitment GO:0045165 99 0.096
Fly
cell growth GO:0016049 57 0.090
Zebrafish
negative regulation of biological process GO:0048519 304 0.089
Zebrafish
regulation of biological quality GO:0065008 263 0.086
Fly
maintenance of location GO:0051235 4 0.085
generation of neurons GO:0048699 385 0.083
Mouse Fly
sensory perception of light stimulus GO:0050953 19 0.081
Zebrafish Mouse
neuron development GO:0048666 262 0.080
Mouse
eye morphogenesis GO:0048592 144 0.078
Mouse
dopamine metabolic process GO:0042417 2 0.076
axon ensheathment in central nervous system GO:0032291 2 0.075
Fly
cellular biosynthetic process GO:0044249 286 0.072
visual perception GO:0007601 17 0.071
Zebrafish Mouse
aging GO:0007568 2 0.069
sequestering of metal ion GO:0051238 3 0.068
phosphorus metabolic process GO:0006793 109 0.067
Yeast Mouse
regulation of signaling GO:0023051 235 0.067
Yeast
regulation of primary metabolic process GO:0080090 311 0.064
Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.063
Worm
regulation of protein binding GO:0043393 3 0.063
nucleoside phosphate biosynthetic process GO:1901293 21 0.062
enzyme linked receptor protein signaling pathway GO:0007167 106 0.061
gene expression GO:0010467 252 0.061
cellular nitrogen compound biosynthetic process GO:0044271 218 0.061
cortical actin cytoskeleton organization GO:0030866 1 0.060
Fly
cellular macromolecule metabolic process GO:0044260 391 0.060
cell surface receptor signaling pathway GO:0007166 325 0.059
Yeast Mouse Fly
ribonucleotide metabolic process GO:0009259 27 0.058
Yeast Mouse
response to external stimulus GO:0009605 264 0.057
Zebrafish Mouse
rho protein signal transduction GO:0007266 5 0.056
Zebrafish
response to drug GO:0042493 3 0.056
cyclic nucleotide biosynthetic process GO:0009190 18 0.056
organic substance biosynthetic process GO:1901576 289 0.055
activation of mapk activity GO:0000187 3 0.055
eye photoreceptor cell differentiation GO:0001754 45 0.054
Mouse
response to chemical GO:0042221 320 0.051
Yeast
sensory system development GO:0048880 76 0.050
organonitrogen compound metabolic process GO:1901564 74 0.050
Yeast Mouse
cellular amino acid metabolic process GO:0006520 7 0.047
regulation of macromolecule metabolic process GO:0060255 317 0.047
regulation of metabolic process GO:0019222 359 0.046
Yeast
response to light intensity GO:0009642 1 0.045
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.045
Yeast
cation homeostasis GO:0055080 33 0.045
posterior lateral line system development GO:0048915 46 0.045
amine metabolic process GO:0009308 2 0.045
cellular amine metabolic process GO:0044106 2 0.045
regulation of signal transduction GO:0009966 225 0.045
Yeast
catechol containing compound metabolic process GO:0009712 2 0.044
establishment of blood brain barrier GO:0060856 2 0.043
Fly
ear development GO:0043583 127 0.043
ion homeostasis GO:0050801 41 0.042
metal ion homeostasis GO:0055065 26 0.042
digestive tract development GO:0048565 265 0.041
Zebrafish
sensory perception of chemical stimulus GO:0007606 3 0.041
Mouse
regulation of cell communication GO:0010646 232 0.040
Yeast
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.040
regulation of nucleotide metabolic process GO:0006140 17 0.039
Yeast
heterocycle biosynthetic process GO:0018130 215 0.039
regulation of phosphorus metabolic process GO:0051174 43 0.039
Yeast
positive regulation of cellular process GO:0048522 201 0.039
regulation of nucleoside metabolic process GO:0009118 2 0.039
Yeast
negative regulation of cellular process GO:0048523 283 0.039
Zebrafish
inorganic ion transmembrane transport GO:0098660 57 0.038
neural retina development GO:0003407 49 0.038
stem cell division GO:0017145 1 0.038
Fly
receptor recycling GO:0001881 4 0.036
regulation of receptor recycling GO:0001919 3 0.036
regulation of biosynthetic process GO:0009889 250 0.036
cyclic nucleotide metabolic process GO:0009187 18 0.035
carboxylic acid metabolic process GO:0019752 22 0.035
single organism metabolic process GO:0044710 217 0.035
Yeast Mouse
response to uv GO:0009411 3 0.034
regulation of circadian sleep wake cycle GO:0042749 1 0.034
positive regulation of signal transduction GO:0009967 56 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.032
response to food GO:0032094 1 0.032
regulation of catalytic activity GO:0050790 55 0.032
Yeast
cellular aromatic compound metabolic process GO:0006725 295 0.032
Yeast Mouse
guanosine containing compound catabolic process GO:1901069 2 0.032
Yeast Mouse
cellular component movement GO:0006928 335 0.031
Yeast Zebrafish
anterior posterior pattern specification GO:0009952 152 0.031
cell migration involved in gastrulation GO:0042074 79 0.031
Zebrafish
biosynthetic process GO:0009058 294 0.030
organelle organization GO:0006996 227 0.029
Yeast Zebrafish Worm Fly
positive regulation of biological process GO:0048518 253 0.029
single organism biosynthetic process GO:0044711 71 0.029
calcium ion homeostasis GO:0055074 19 0.028
regulation of circadian rhythm GO:0042752 4 0.028
cellular component morphogenesis GO:0032989 336 0.028
Zebrafish
phagocytosis GO:0006909 3 0.028
protein metabolic process GO:0019538 183 0.028
regulation of gtp catabolic process GO:0033124 2 0.028
Yeast
regulation of cellular amine metabolic process GO:0033238 0 0.027
organic acid metabolic process GO:0006082 31 0.027
epiboly GO:0090504 41 0.027
Zebrafish
negative regulation of signaling GO:0023057 96 0.027
protein modification by small protein removal GO:0070646 1 0.026
ribose phosphate biosynthetic process GO:0046390 20 0.026
purine ribonucleotide metabolic process GO:0009150 27 0.026
Yeast Mouse
mechanosensory lateral line system development GO:0048881 49 0.026
nucleoside phosphate metabolic process GO:0006753 28 0.026
Yeast Mouse
negative regulation of signal transduction GO:0009968 94 0.026
actomyosin structure organization GO:0031032 53 0.026
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.026
regulation of cyclase activity GO:0031279 12 0.026
blood vessel development GO:0001568 246 0.026
Zebrafish
lipid storage GO:0019915 1 0.025
cellular cation homeostasis GO:0030003 17 0.025
negative regulation of defense response GO:0031348 2 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
catechol containing compound biosynthetic process GO:0009713 2 0.024
cell morphogenesis GO:0000902 289 0.024
Zebrafish
catecholamine metabolic process GO:0006584 2 0.024
cellular ketone metabolic process GO:0042180 11 0.024
regulation of guanylate cyclase activity GO:0031282 6 0.024
intracellular estrogen receptor signaling pathway GO:0030520 3 0.024
response to organic substance GO:0010033 153 0.024
Yeast
nucleotide metabolic process GO:0009117 28 0.023
Yeast Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.023
calcium mediated signaling GO:0019722 2 0.023
Fly
regulation of gene expression GO:0010468 265 0.023
protein modification process GO:0036211 100 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
axon extension GO:0048675 45 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
Yeast
transcription from rna polymerase ii promoter GO:0006366 80 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.022
Yeast
regulation of transcription dna templated GO:0006355 213 0.022
positive regulation of signaling GO:0023056 56 0.022
purine containing compound biosynthetic process GO:0072522 20 0.022
neuron differentiation GO:0030182 353 0.022
Mouse
gtp catabolic process GO:0006184 2 0.022
Yeast Mouse
axis specification GO:0009798 43 0.021
Worm
response to amphetamine GO:0001975 1 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
rna biosynthetic process GO:0032774 181 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
Yeast Mouse
circadian regulation of gene expression GO:0032922 8 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
Yeast Mouse
actin filament based process GO:0030029 64 0.021
Zebrafish Fly
regeneration GO:0031099 91 0.020
establishment of endothelial barrier GO:0061028 3 0.020
Fly
detection of light stimulus involved in sensory perception GO:0050962 7 0.020
Zebrafish Mouse
tube morphogenesis GO:0035239 349 0.020
Zebrafish
neurological system process GO:0050877 62 0.020
Zebrafish Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
growth GO:0040007 174 0.020
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.019
negative regulation of retinal cell programmed cell death GO:0046671 2 0.019
positive regulation of transport GO:0051050 2 0.019
purine containing compound metabolic process GO:0072521 29 0.019
Yeast Mouse
photoreceptor cell fate commitment GO:0046552 1 0.019
segmentation GO:0035282 97 0.019
guanosine containing compound metabolic process GO:1901068 4 0.018
Yeast Mouse
alpha amino acid metabolic process GO:1901605 3 0.018
transmission of nerve impulse GO:0019226 19 0.018
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
Yeast
phosphorylation GO:0016310 69 0.018
regulation of inflammatory response GO:0050727 2 0.018
detection of stimulus involved in sensory perception GO:0050906 21 0.018
Zebrafish Mouse
embryonic organ development GO:0048568 381 0.018
intracellular signal transduction GO:0035556 85 0.017
Yeast Zebrafish Fly
developmental programmed cell death GO:0010623 4 0.017
camera type eye photoreceptor cell differentiation GO:0060219 19 0.017
response to oxygen containing compound GO:1901700 55 0.017
positive regulation of metabolic process GO:0009893 108 0.017
cellular response to organic substance GO:0071310 105 0.017
Yeast
vitamin a biosynthetic process GO:0035238 1 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
Yeast Mouse
positive regulation of cell communication GO:0010647 56 0.017
response to nicotine GO:0035094 2 0.017
localization of cell GO:0051674 244 0.016
Zebrafish
response to endogenous stimulus GO:0009719 83 0.016
regulation of molecular function GO:0065009 70 0.016
Yeast
cellular response to estrogen stimulus GO:0071391 24 0.016
light adaption GO:0036367 1 0.016
meiotic nuclear division GO:0007126 4 0.016
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.016
inorganic anion transport GO:0015698 25 0.016
regulation of kinase activity GO:0043549 15 0.016
cyclic purine nucleotide metabolic process GO:0052652 18 0.016
regulation of protein metabolic process GO:0051246 56 0.016
response to amine GO:0014075 1 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
protein complex disassembly GO:0043241 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
positive regulation of endothelial cell differentiation GO:0045603 2 0.015
inner ear development GO:0048839 126 0.015
regulation of response to stimulus GO:0048583 269 0.015
Yeast
developmental growth GO:0048589 166 0.015
Zebrafish
cellular response to decreased oxygen levels GO:0036294 1 0.015
organonitrogen compound biosynthetic process GO:1901566 47 0.015
cellular response to abiotic stimulus GO:0071214 4 0.015
Mouse
regulation of reproductive process GO:2000241 4 0.015
cellular calcium ion homeostasis GO:0006874 13 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
developmental cell growth GO:0048588 52 0.015
positive regulation of cell division GO:0051781 2 0.015
lateral line system development GO:0048925 76 0.015
rhombomere 6 development GO:0021572 4 0.015
ear morphogenesis GO:0042471 64 0.015
divalent inorganic cation homeostasis GO:0072507 22 0.015
cell fate specification GO:0001708 68 0.015
skeletal system development GO:0001501 181 0.015
retinal cone cell development GO:0046549 8 0.014
embryonic skeletal joint morphogenesis GO:0060272 3 0.014
regulation of chemotaxis GO:0050920 18 0.014
inorganic anion transmembrane transport GO:0098661 10 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of transferase activity GO:0051338 16 0.014
chemosensory behavior GO:0007635 1 0.014
system process GO:0003008 185 0.014
Zebrafish Mouse Fly
cellular ion homeostasis GO:0006873 17 0.014
pancreas development GO:0031016 84 0.014
regulation of binding GO:0051098 3 0.014
endothelium development GO:0003158 25 0.014
Fly
negative regulation of rna metabolic process GO:0051253 48 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.014
circadian sleep wake cycle process GO:0022410 2 0.014
sleep GO:0030431 1 0.014
inner ear morphogenesis GO:0042472 63 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
Yeast
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
Zebrafish
cellular protein metabolic process GO:0044267 129 0.013
heart development GO:0007507 313 0.013
Zebrafish
regulation of axon extension involved in axon guidance GO:0048841 6 0.013
locomotion GO:0040011 313 0.013
Zebrafish
regulation of response to external stimulus GO:0032101 31 0.013
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.013
behavior GO:0007610 74 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
ras protein signal transduction GO:0007265 7 0.013
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
Yeast Mouse
gtp metabolic process GO:0046039 4 0.012
Yeast Mouse
chordate embryonic development GO:0043009 271 0.012
regulation of programmed cell death GO:0043067 101 0.012
cell cycle GO:0007049 93 0.012
Worm Fly
cellular protein modification process GO:0006464 100 0.012
synaptic vesicle localization GO:0097479 1 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
positive regulation of phosphorus metabolic process GO:0010562 21 0.012
indole containing compound metabolic process GO:0042430 2 0.012
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.012
purine ribonucleotide biosynthetic process GO:0009152 20 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
cation transmembrane transport GO:0098655 65 0.012
adult behavior GO:0030534 2 0.012
inner ear receptor cell fate commitment GO:0060120 4 0.012
septum transversum development GO:0003343 4 0.012
rhombomere 5 development GO:0021571 4 0.012
negative regulation of metabolic process GO:0009892 86 0.012
positive regulation of cgmp biosynthetic process GO:0030828 6 0.012
response to stress GO:0006950 263 0.012
serotonin metabolic process GO:0042428 1 0.012
immune system process GO:0002376 241 0.012
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.012
cell proliferation GO:0008283 80 0.011
Mouse Fly
morphogenesis of an epithelium GO:0002009 333 0.011
Zebrafish
positive regulation of striated muscle tissue development GO:0045844 1 0.011
rhythmic behavior GO:0007622 5 0.011
head development GO:0060322 303 0.011
establishment of organelle localization GO:0051656 45 0.011
Yeast Worm Fly
optokinetic behavior GO:0007634 9 0.011
nucleic acid templated transcription GO:0097659 181 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
Zebrafish
thermosensory behavior GO:0040040 1 0.011
digestive system development GO:0055123 289 0.011
Zebrafish
proepicardium development GO:0003342 4 0.011
cell motility GO:0048870 244 0.011
Zebrafish
regulation of protein transport GO:0051223 3 0.011
Yeast
transcription dna templated GO:0006351 181 0.011
protein desumoylation GO:0016926 1 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
Yeast
embryonic heart tube morphogenesis GO:0003143 108 0.011
positive regulation of guanylate cyclase activity GO:0031284 6 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
positive regulation of catalytic activity GO:0043085 25 0.011
polarized epithelial cell differentiation GO:0030859 4 0.010
cellular protein complex disassembly GO:0043624 1 0.010
oxidation reduction process GO:0055114 41 0.010
regulation of gtpase activity GO:0043087 2 0.010
Yeast
regulation of intracellular signal transduction GO:1902531 57 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
central nervous system development GO:0007417 387 0.010
Fly
negative regulation of cell communication GO:0010648 96 0.010
neuron fate determination GO:0048664 2 0.010
regulation of transporter activity GO:0032409 2 0.010
ribonucleotide biosynthetic process GO:0009260 20 0.010
neuron projection regeneration GO:0031102 16 0.010
retina layer formation GO:0010842 24 0.010
chemical homeostasis GO:0048878 49 0.010
single organism nuclear import GO:1902593 3 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.010
single organism organelle organization GO:1902589 199 0.010
Zebrafish Worm Fly

gnat1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.616
disease of anatomical entity DOID:7 0 0.616
eye and adnexa disease DOID:1492 0 0.616
nervous system disease DOID:863 0 0.616
eye disease DOID:5614 0 0.616
retinal disease DOID:5679 0 0.467
retinal degeneration DOID:8466 0 0.191
retinitis pigmentosa DOID:10584 0 0.065