Danio rerio

18 known processes

plxnb2a

plexin b2a

(Aliases: plxnB2,fk37b01,si:dkey-261e22.2,wu:fk37b01,im:7054697)

plxnb2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.903
Mouse
negative regulation of cellular process GO:0048523 283 0.747
ribose phosphate metabolic process GO:0019693 27 0.726
Mouse
response to external stimulus GO:0009605 264 0.708
Zebrafish
regulation of multicellular organismal development GO:2000026 223 0.674
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.670
Mouse
axon guidance GO:0007411 86 0.666
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.652
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.610
Mouse
regulation of metabolic process GO:0019222 359 0.581
Mouse
nitrogen compound metabolic process GO:0006807 319 0.518
Mouse
taxis GO:0042330 109 0.496
Zebrafish
guanosine containing compound metabolic process GO:1901068 4 0.481
Mouse
regulation of signal transduction GO:0009966 225 0.454
Mouse
ameboidal type cell migration GO:0001667 143 0.451
embryo development ending in birth or egg hatching GO:0009792 271 0.443
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.443
regulation of signaling GO:0023051 235 0.429
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.422
Zebrafish Mouse
aromatic compound biosynthetic process GO:0019438 217 0.417
chordate embryonic development GO:0043009 271 0.411
Zebrafish Mouse
ribonucleotide metabolic process GO:0009259 27 0.410
Mouse
response to light stimulus GO:0009416 46 0.408
cellular biosynthetic process GO:0044249 286 0.408
regulation of axonogenesis GO:0050770 32 0.404
Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.399
regulation of biological quality GO:0065008 263 0.396
Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.395
Mouse
developmental process involved in reproduction GO:0003006 27 0.395
regulation of gtp catabolic process GO:0033124 2 0.388
Mouse
cell projection morphogenesis GO:0048858 244 0.387
Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.384
Mouse
gene expression GO:0010467 252 0.384
cellular component morphogenesis GO:0032989 336 0.384
Zebrafish Mouse
regulation of hydrolase activity GO:0051336 28 0.382
Mouse
regulation of cell differentiation GO:0045595 142 0.379
Zebrafish Mouse
head development GO:0060322 303 0.378
Mouse
regulation of oocyte development GO:0060281 3 0.371
negative regulation of biological process GO:0048519 304 0.361
cellular nitrogen compound metabolic process GO:0034641 290 0.356
Mouse
programmed cell death GO:0012501 119 0.350
regulation of nucleoside metabolic process GO:0009118 2 0.342
Mouse
heterocycle metabolic process GO:0046483 290 0.337
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.336
purine ribonucleotide metabolic process GO:0009150 27 0.331
Mouse
organic substance biosynthetic process GO:1901576 289 0.329
protein metabolic process GO:0019538 183 0.326
Mouse
blood vessel morphogenesis GO:0048514 216 0.321
regulation of primary metabolic process GO:0080090 311 0.317
Mouse
apoptotic process GO:0006915 116 0.317
organic cyclic compound metabolic process GO:1901360 301 0.316
Mouse
guanosine containing compound catabolic process GO:1901069 2 0.316
Mouse
neurological system process GO:0050877 62 0.310
regulation of cell communication GO:0010646 232 0.309
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.308
Mouse
cell migration involved in gastrulation GO:0042074 79 0.304
nucleotide metabolic process GO:0009117 28 0.296
Mouse
regulation of cell size GO:0008361 29 0.290
Zebrafish
regulation of developmental process GO:0050793 247 0.289
Zebrafish Mouse
positive regulation of cellular process GO:0048522 201 0.287
Mouse
regulation of apoptotic process GO:0042981 98 0.276
regulation of growth GO:0040008 42 0.273
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.271
Mouse
regulation of transcription dna templated GO:0006355 213 0.270
central nervous system development GO:0007417 387 0.262
Mouse
response to chemical GO:0042221 320 0.261
Zebrafish
cellular component movement GO:0006928 335 0.260
Zebrafish Mouse
cell death GO:0008219 121 0.259
cell projection organization GO:0030030 284 0.258
Zebrafish Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.258
stem cell maintenance GO:0019827 4 0.257
regulation of cell shape GO:0008360 1 0.255
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.244
cellular macromolecule metabolic process GO:0044260 391 0.240
Mouse
embryonic skeletal joint morphogenesis GO:0060272 3 0.236
Zebrafish
regulation of response to stimulus GO:0048583 269 0.234
Mouse
regulation of biosynthetic process GO:0009889 250 0.230
generation of neurons GO:0048699 385 0.228
Zebrafish Mouse
regulation of synapse organization GO:0050807 3 0.228
tube morphogenesis GO:0035239 349 0.224
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.223
positive regulation of cellular component biogenesis GO:0044089 3 0.222
neuron projection development GO:0031175 180 0.222
Zebrafish Mouse
signal transduction GO:0007165 455 0.215
Mouse
multicellular organism growth GO:0035264 4 0.209
negative regulation of synapse assembly GO:0051964 2 0.203
cell growth GO:0016049 57 0.203
Zebrafish
cellular carbohydrate metabolic process GO:0044262 4 0.195
larval development GO:0002164 2 0.192
cellular component biogenesis GO:0044085 178 0.191
neuron projection guidance GO:0097485 86 0.191
Zebrafish
dorsal convergence GO:0060030 14 0.190
negative regulation of chemotaxis GO:0050922 4 0.189
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.184
Zebrafish Mouse
small molecule metabolic process GO:0044281 77 0.184
Mouse
regulation of anatomical structure size GO:0090066 33 0.184
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.184
regulation of protein polymerization GO:0032271 2 0.180
regulation of cellular biosynthetic process GO:0031326 245 0.180
biosynthetic process GO:0009058 294 0.175
axonal defasciculation GO:0007414 2 0.173
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.170
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.169
response to abiotic stimulus GO:0009628 122 0.169
regulation of purine nucleotide metabolic process GO:1900542 17 0.165
Mouse
axonogenesis GO:0007409 152 0.165
Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.162
regulation of multicellular organism growth GO:0040014 4 0.161
catabolic process GO:0009056 32 0.155
Mouse
establishment of localization GO:0051234 244 0.153
positive regulation of nucleic acid templated transcription GO:1903508 57 0.152
organonitrogen compound metabolic process GO:1901564 74 0.151
Mouse
regulation of carbohydrate metabolic process GO:0006109 4 0.150
regulation of catalytic activity GO:0050790 55 0.150
Mouse
synaptic growth at neuromuscular junction GO:0051124 2 0.149
regulation of programmed cell death GO:0043067 101 0.149
phosphorus metabolic process GO:0006793 109 0.147
Mouse
digestive tract mesoderm development GO:0007502 1 0.144
regulation of developmental growth GO:0048638 38 0.143
Zebrafish
death GO:0016265 121 0.142
organic cyclic compound biosynthetic process GO:1901362 223 0.142
locomotion GO:0040011 313 0.142
Zebrafish Mouse
negative regulation of metabolic process GO:0009892 86 0.141
cellular macromolecule biosynthetic process GO:0034645 224 0.140
blood vessel development GO:0001568 246 0.138
regulation of neuron differentiation GO:0045664 56 0.137
Zebrafish Mouse
chemotaxis GO:0006935 104 0.136
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.136
transcription dna templated GO:0006351 181 0.134
stem cell differentiation GO:0048863 117 0.134
ribonucleoside metabolic process GO:0009119 11 0.134
Mouse
regulation of gene expression GO:0010468 265 0.133
positive regulation of cellular catabolic process GO:0031331 3 0.131
regulation of cell death GO:0010941 103 0.128
extrinsic apoptotic signaling pathway GO:0097191 3 0.128
regulation of rna metabolic process GO:0051252 224 0.128
tube closure GO:0060606 1 0.127
Mouse
gtp catabolic process GO:0006184 2 0.127
Mouse
transmission of nerve impulse GO:0019226 19 0.127
embryonic skeletal system morphogenesis GO:0048704 93 0.127
Zebrafish
neuron differentiation GO:0030182 353 0.126
Zebrafish Mouse
positive regulation of cell projection organization GO:0031346 9 0.126
Mouse
macromolecular complex assembly GO:0065003 35 0.124
primary neural tube formation GO:0014020 1 0.124
Mouse
convergent extension involved in gastrulation GO:0060027 71 0.123
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.122
regulation of rho protein signal transduction GO:0035023 2 0.119
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.119
Zebrafish Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.118
regulation of nervous system development GO:0051960 90 0.118
Zebrafish Mouse
growth GO:0040007 174 0.116
Zebrafish
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.116
nucleic acid templated transcription GO:0097659 181 0.114
branching morphogenesis of a nerve GO:0048755 4 0.112
Zebrafish
positive regulation of apoptotic process GO:0043065 29 0.111
actin filament polymerization GO:0030041 2 0.111
organic substance catabolic process GO:1901575 28 0.111
Mouse
autophagy GO:0006914 4 0.110
vasculature development GO:0001944 278 0.104
protein polymerization GO:0051258 4 0.104
protein import GO:0017038 3 0.103
regulation of synapse assembly GO:0051963 3 0.103
aromatic compound catabolic process GO:0019439 15 0.102
Mouse
nitric oxide metabolic process GO:0046209 2 0.102
actin polymerization or depolymerization GO:0008154 2 0.102
positive regulation of metabolic process GO:0009893 108 0.100
regulation of gtpase activity GO:0043087 2 0.099
Mouse
cellular catabolic process GO:0044248 27 0.099
Mouse
anterior posterior pattern specification GO:0009952 152 0.099
response to radiation GO:0009314 51 0.099
cellular macromolecular complex assembly GO:0034622 24 0.098
gtp metabolic process GO:0046039 4 0.098
Mouse
cell migration involved in vasculogenesis GO:0035441 1 0.096
modification dependent macromolecule catabolic process GO:0043632 3 0.095
regulation of epithelial cell proliferation GO:0050678 3 0.095
negative regulation of axon guidance GO:1902668 1 0.095
phosphate containing compound metabolic process GO:0006796 108 0.095
Mouse
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.093
gland development GO:0048732 143 0.092
positive regulation of apoptotic signaling pathway GO:2001235 1 0.092
rna biosynthetic process GO:0032774 181 0.091
positive regulation of cellular metabolic process GO:0031325 94 0.091
inner ear morphogenesis GO:0042472 63 0.090
regulation of organ growth GO:0046620 3 0.090
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.089
regulation of peptidase activity GO:0052547 23 0.088
rna metabolic process GO:0016070 219 0.088
embryonic organ development GO:0048568 381 0.088
Zebrafish
protein dephosphorylation GO:0006470 3 0.087
sprouting angiogenesis GO:0002040 53 0.087
neuron projection morphogenesis GO:0048812 161 0.086
Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.086
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.086
purine nucleotide metabolic process GO:0006163 27 0.086
Mouse
energy reserve metabolic process GO:0006112 2 0.086
regulation of rna biosynthetic process GO:2001141 213 0.086
regulation of macromolecule biosynthetic process GO:0010556 225 0.085
peptidyl threonine phosphorylation GO:0018107 1 0.085
organophosphate metabolic process GO:0019637 37 0.084
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.083
positive regulation of catabolic process GO:0009896 4 0.083
positive regulation of gene expression GO:0010628 71 0.081
cellular ketone metabolic process GO:0042180 11 0.081
gastrulation GO:0007369 208 0.080
localization of cell GO:0051674 244 0.079
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 2 0.079
positive regulation of developmental process GO:0051094 50 0.078
Mouse
cellular component assembly GO:0022607 170 0.077
digestive system development GO:0055123 289 0.077
somite development GO:0061053 96 0.075
medulla oblongata development GO:0021550 4 0.075
cell migration GO:0016477 237 0.074
Mouse
response to organic substance GO:0010033 153 0.073
mesoderm development GO:0007498 88 0.072
segmentation GO:0035282 97 0.070
detection of stimulus GO:0051606 29 0.070
cell motility GO:0048870 244 0.070
Mouse
mesenchyme development GO:0060485 127 0.068
regulation of protein catabolic process GO:0042176 1 0.068
nitric oxide biosynthetic process GO:0006809 2 0.068
cellular protein catabolic process GO:0044257 4 0.068
branchiomotor neuron axon guidance GO:0021785 1 0.068
carbohydrate derivative metabolic process GO:1901135 61 0.068
Mouse
positive regulation of protein polymerization GO:0032273 2 0.067
single organism biosynthetic process GO:0044711 71 0.067
regulation of carbohydrate biosynthetic process GO:0043255 1 0.067
purine containing compound metabolic process GO:0072521 29 0.067
Mouse
pyruvate metabolic process GO:0006090 1 0.066
positive regulation of cellular biosynthetic process GO:0031328 68 0.066
ras protein signal transduction GO:0007265 7 0.066
meiotic nuclear division GO:0007126 4 0.066
axon development GO:0061564 166 0.066
Zebrafish Mouse
stem cell development GO:0048864 82 0.065
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.065
positive regulation of multicellular organismal process GO:0051240 52 0.064
Mouse
somitogenesis GO:0001756 87 0.064
regulation of protein complex assembly GO:0043254 3 0.064
regulation of neuron projection development GO:0010975 40 0.064
Zebrafish Mouse
regulation of fatty acid metabolic process GO:0019217 1 0.063
nucleobase containing small molecule metabolic process GO:0055086 32 0.063
Mouse
regulation of cell motility GO:2000145 46 0.063
Mouse
regulation of reproductive process GO:2000241 4 0.062
sensory organ development GO:0007423 393 0.062
regulation of locomotion GO:0040012 55 0.062
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.062
notochord development GO:0030903 54 0.061
protein localization to nucleus GO:0034504 3 0.061
response to stress GO:0006950 263 0.061
detection of abiotic stimulus GO:0009582 24 0.061
aging GO:0007568 2 0.060
regulation of multicellular organismal process GO:0051239 277 0.060
Zebrafish Mouse
reproduction GO:0000003 40 0.060
modification by symbiont of host morphology or physiology GO:0044003 4 0.059
regulation of cysteine type endopeptidase activity GO:2000116 21 0.059
regulation of cell migration GO:0030334 40 0.059
Mouse
motor neuron axon guidance GO:0008045 23 0.058
Zebrafish
digestive tract development GO:0048565 265 0.058
peptidyl serine phosphorylation GO:0018105 1 0.058
positive regulation of inflammatory response GO:0050729 1 0.058
pathway restricted smad protein phosphorylation GO:0060389 1 0.058
system process GO:0003008 185 0.057
enzyme linked receptor protein signaling pathway GO:0007167 106 0.056
positive regulation of cell adhesion GO:0045785 1 0.056
cell part morphogenesis GO:0032990 246 0.056
Zebrafish Mouse
regulation of cellular component size GO:0032535 30 0.054
Zebrafish
cell morphogenesis GO:0000902 289 0.054
Zebrafish Mouse
regulation of neurogenesis GO:0050767 87 0.054
Zebrafish Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.054
cellular response to dna damage stimulus GO:0006974 24 0.054
reproductive process GO:0022414 40 0.054
convergent extension GO:0060026 118 0.054
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.053
regulation of cellular response to growth factor stimulus GO:0090287 35 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.053
maternal determination of anterior posterior axis embryo GO:0008358 4 0.052
ubiquitin dependent protein catabolic process GO:0006511 3 0.052
tissue migration GO:0090130 37 0.052
lipid catabolic process GO:0016042 4 0.052
syncytium formation GO:0006949 12 0.051
adherens junction maintenance GO:0034334 2 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.050
cyclic nucleotide biosynthetic process GO:0009190 18 0.050
cellular biogenic amine metabolic process GO:0006576 2 0.050
positive regulation of biological process GO:0048518 253 0.050
Mouse
negative regulation of cell death GO:0060548 60 0.050
regulation of cell morphogenesis GO:0022604 42 0.049
Zebrafish Mouse
single organism localization GO:1902578 225 0.049
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.049
development of primary female sexual characteristics GO:0046545 4 0.049
regulation of glucose transport GO:0010827 1 0.049
regulation of hormone secretion GO:0046883 2 0.048
regulation of oligodendrocyte differentiation GO:0048713 1 0.048
embryonic heart tube development GO:0035050 133 0.047
neuronal action potential GO:0019228 18 0.047
organelle organization GO:0006996 227 0.047
heterocycle catabolic process GO:0046700 15 0.047
Mouse
single organism reproductive process GO:0044702 40 0.047
response to endogenous stimulus GO:0009719 83 0.046
regulation of stem cell differentiation GO:2000736 4 0.046
positive regulation of protein complex assembly GO:0031334 2 0.046
transport GO:0006810 220 0.046
germ line stem cell division GO:0042078 1 0.046
negative regulation of cell communication GO:0010648 96 0.046
epithelium migration GO:0090132 25 0.046
regulation of membrane potential GO:0042391 23 0.046
cellular response to chemical stimulus GO:0070887 157 0.045
reactive oxygen species biosynthetic process GO:1903409 1 0.045
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.045
pronuclear migration GO:0035046 1 0.045
regulation of cell development GO:0060284 100 0.045
Zebrafish Mouse
glucose import GO:0046323 2 0.044
morphogenesis of embryonic epithelium GO:0016331 30 0.043
Mouse
pole plasm assembly GO:0007315 4 0.043
regulation of embryonic development GO:0045995 47 0.043
establishment of protein localization to plasma membrane GO:0090002 1 0.043
regulation of purine nucleotide catabolic process GO:0033121 2 0.043
Mouse
negative regulation of gene expression GO:0010629 65 0.043
nucleobase containing compound catabolic process GO:0034655 15 0.042
Mouse
regulation of skeletal muscle tissue development GO:0048641 4 0.042
response to alkaloid GO:0043279 2 0.042
modification dependent protein catabolic process GO:0019941 3 0.042
chondrocyte development GO:0002063 4 0.042
positive regulation of proteolysis GO:0045862 10 0.042
multicellular organismal signaling GO:0035637 22 0.041
regulation of ras gtpase activity GO:0032318 2 0.041
Mouse
positive regulation of carbohydrate metabolic process GO:0045913 1 0.041
digestive tract morphogenesis GO:0048546 231 0.041
membrane fusion GO:0061025 2 0.041
developmental growth GO:0048589 166 0.041
Zebrafish
positive regulation of oocyte development GO:0060282 1 0.041
carbohydrate biosynthetic process GO:0016051 1 0.041
diencephalon development GO:0021536 58 0.041
germ line stem cell maintenance GO:0030718 2 0.041
bmp signaling pathway GO:0030509 52 0.041
positive regulation of nervous system development GO:0051962 25 0.041
Mouse
amine metabolic process GO:0009308 2 0.040
mechanosensory behavior GO:0007638 2 0.040
maintenance of location GO:0051235 4 0.040
cell substrate adhesion GO:0031589 4 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
positive regulation of gtp catabolic process GO:0033126 1 0.040
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.040
hypothalamus cell differentiation GO:0021979 4 0.040
hormone secretion GO:0046879 2 0.039
positive regulation of epithelial cell migration GO:0010634 2 0.039
positive regulation of macromolecule metabolic process GO:0010604 93 0.039
cellular amine metabolic process GO:0044106 2 0.039
epithelial tube formation GO:0072175 19 0.039
Mouse
developmental cell growth GO:0048588 52 0.039
Zebrafish
response to hexose GO:0009746 3 0.039
positive regulation of gtpase activity GO:0043547 1 0.039
negative regulation of programmed cell death GO:0043069 58 0.039
hindbrain development GO:0030902 91 0.038
signal transduction in absence of ligand GO:0038034 1 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.037
cellular component maintenance GO:0043954 3 0.037
protein complex biogenesis GO:0070271 30 0.036
positive regulation of endopeptidase activity GO:0010950 10 0.036
neuroblast proliferation GO:0007405 2 0.036
Mouse
positive regulation of hydrolase activity GO:0051345 13 0.036
positive regulation of programmed cell death GO:0043068 29 0.036
regulation of response to cytokine stimulus GO:0060759 3 0.036
phosphorylation GO:0016310 69 0.036
Mouse
nucleocytoplasmic transport GO:0006913 4 0.035
lipid storage GO:0019915 1 0.035
cellular response to organic substance GO:0071310 105 0.035
negative regulation of cellular biosynthetic process GO:0031327 55 0.035
negative regulation of biosynthetic process GO:0009890 55 0.035
stem cell division GO:0017145 1 0.035
regulation of rho gtpase activity GO:0032319 1 0.035
Mouse
peptidyl serine modification GO:0018209 2 0.035
regulation of cytoplasmic transport GO:1903649 4 0.035
peptidyl threonine modification GO:0018210 1 0.034
regulation of cellular component movement GO:0051270 55 0.034
Mouse
regulation of myelination GO:0031641 1 0.034
modulation by virus of host morphology or physiology GO:0019048 1 0.034
response to carbohydrate GO:0009743 3 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
negative regulation of epithelial cell migration GO:0010633 1 0.034
forebrain development GO:0030900 96 0.034
action potential GO:0001508 19 0.034
muscle tissue development GO:0060537 110 0.034
negative regulation of macromolecule metabolic process GO:0010605 76 0.033
purine nucleoside triphosphate metabolic process GO:0009144 9 0.033
Mouse
lateral inhibition GO:0046331 1 0.033
single organism cell adhesion GO:0098602 29 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
microtubule based process GO:0007017 60 0.033
regulation of glucose import GO:0046324 1 0.033
negative regulation of apoptotic process GO:0043066 55 0.032
toxin metabolic process GO:0009404 1 0.032
positive regulation of nucleoside metabolic process GO:0045979 1 0.032
reactive oxygen species metabolic process GO:0072593 6 0.032
eye development GO:0001654 277 0.032
positive regulation of cell differentiation GO:0045597 30 0.032
Mouse
small gtpase mediated signal transduction GO:0007264 8 0.031
brain development GO:0007420 293 0.031
Mouse
response to other organism GO:0051707 97 0.031
response to wounding GO:0009611 116 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.031
peripheral nervous system neuron differentiation GO:0048934 28 0.031
regulation of localization GO:0032879 104 0.031
Mouse
actin cytoskeleton organization GO:0030036 63 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
detection of external stimulus GO:0009581 24 0.031
mitochondrion organization GO:0007005 4 0.031
cellular response to toxic substance GO:0097237 1 0.031
regulation of chemotaxis GO:0050920 18 0.031
regulation of cell projection organization GO:0031344 44 0.031
Zebrafish Mouse
proteasomal protein catabolic process GO:0010498 2 0.030
regulation of cytokine mediated signaling pathway GO:0001959 3 0.030
rho protein signal transduction GO:0007266 5 0.030
negative regulation of catabolic process GO:0009895 3 0.030
cellular lipid catabolic process GO:0044242 3 0.030
regulation of intracellular signal transduction GO:1902531 57 0.030
Mouse
negative chemotaxis GO:0050919 1 0.030
negative regulation of cell differentiation GO:0045596 46 0.030
protein complex subunit organization GO:0071822 46 0.030
regionalization GO:0003002 274 0.030
nucleoside metabolic process GO:0009116 11 0.030
Mouse
regulation of actin cytoskeleton organization GO:0032956 8 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
Zebrafish
neuron development GO:0048666 262 0.029
Zebrafish Mouse
mesoderm morphogenesis GO:0048332 51 0.029
hepaticobiliary system development GO:0061008 98 0.029
response to glucose GO:0009749 3 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
regulation of phosphorus metabolic process GO:0051174 43 0.028
Mouse
cellular localization GO:0051641 97 0.028
innervation GO:0060384 3 0.028
muscle cell migration GO:0014812 4 0.028
neural tube development GO:0021915 62 0.028
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.028
muscle cell differentiation GO:0042692 139 0.028
camera type eye development GO:0043010 222 0.028
protein homooligomerization GO:0051260 3 0.028
liver development GO:0001889 96 0.028
nuclear transport GO:0051169 4 0.028
multi organism cellular process GO:0044764 2 0.028
response to nutrient GO:0007584 3 0.027
epithelial tube morphogenesis GO:0060562 148 0.027
Mouse
muscle structure development GO:0061061 196 0.027
response to monosaccharide GO:0034284 3 0.027
regulation of inner ear receptor cell differentiation GO:2000980 1 0.027
organic substance transport GO:0071702 58 0.027
regulation of proteolysis GO:0030162 24 0.027
negative regulation of cellular metabolic process GO:0031324 77 0.027
positive regulation of neuron differentiation GO:0045666 12 0.027
Mouse
oocyte differentiation GO:0009994 14 0.027
negative regulation of signaling GO:0023057 96 0.027
cellular response to organic cyclic compound GO:0071407 38 0.027
facial nerve morphogenesis GO:0021610 1 0.027
pharyngeal muscle development GO:0043282 4 0.027
embryonic epithelial tube formation GO:0001838 17 0.026
Mouse
negative regulation of rna metabolic process GO:0051253 48 0.026
epithelial cell morphogenesis GO:0003382 2 0.026
angiogenesis GO:0001525 158 0.026
negative regulation of signal transduction GO:0009968 94 0.026
glial cell migration GO:0008347 3 0.026
cellular nitrogen compound catabolic process GO:0044270 15 0.026
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
axonogenesis involved in innervation GO:0060385 1 0.026
smad protein complex assembly GO:0007183 1 0.025
response to organic cyclic compound GO:0014070 51 0.025
ion homeostasis GO:0050801 41 0.025
regulation of cytoskeleton organization GO:0051493 11 0.025
cytokinesis GO:0000910 3 0.025
response to mechanical stimulus GO:0009612 24 0.025
positive regulation of cytoskeleton organization GO:0051495 3 0.025
epithelial cell differentiation GO:0030855 116 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.024
Zebrafish Mouse
axon ensheathment GO:0008366 18 0.024
posterior lateral line development GO:0048916 38 0.024
hexose transport GO:0008645 6 0.024
nuclear migration GO:0007097 3 0.024
detection of light stimulus GO:0009583 12 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
response to corticosteroid GO:0031960 1 0.024
negative regulation of developmental process GO:0051093 65 0.024
fertilization GO:0009566 3 0.024
photoperiodism GO:0009648 11 0.023
single organism membrane fusion GO:0044801 2 0.023
mesenchymal cell differentiation GO:0048762 87 0.023
meiotic cell cycle process GO:1903046 3 0.023
regulation of inflammatory response GO:0050727 2 0.023
internal protein amino acid acetylation GO:0006475 2 0.023

plxnb2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
cardiovascular system disease DOID:1287 0 0.028
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
heart disease DOID:114 0 0.024
cardiomyopathy DOID:0050700 0 0.024
intrinsic cardiomyopathy DOID:0060036 0 0.024
musculoskeletal system disease DOID:17 0 0.024
muscle tissue disease DOID:66 0 0.024