Danio rerio

0 known processes

dopey1

dopey family member 1

(Aliases: im:6911215,im:7148241)

dopey1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.242
nitrogen compound metabolic process GO:0006807 319 0.179
regulation of mrna splicing via spliceosome GO:0048024 3 0.124
brain development GO:0007420 293 0.120
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.115
cellular macromolecule metabolic process GO:0044260 391 0.109
guanosine containing compound catabolic process GO:1901069 2 0.108
guanosine containing compound metabolic process GO:1901068 4 0.101
neuron differentiation GO:0030182 353 0.101
phagocytosis GO:0006909 3 0.097
regulation of synapse organization GO:0050807 3 0.097
embryonic organ development GO:0048568 381 0.090
startle response GO:0001964 4 0.088
morphogenesis of an epithelium GO:0002009 333 0.086
axonal fasciculation GO:0007413 11 0.085
cell motility GO:0048870 244 0.085
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.084
regulation of cell communication GO:0010646 232 0.078
organic cyclic compound metabolic process GO:1901360 301 0.076
cell migration involved in vasculogenesis GO:0035441 1 0.075
gland development GO:0048732 143 0.073
response to chemical GO:0042221 320 0.072
regulation of signal transduction GO:0009966 225 0.072
sensory organ development GO:0007423 393 0.071
negative regulation of leukocyte migration GO:0002686 3 0.071
cell projection morphogenesis GO:0048858 244 0.071
negative regulation of protein phosphorylation GO:0001933 4 0.068
gtp catabolic process GO:0006184 2 0.068
negative regulation of cell communication GO:0010648 96 0.065
generation of neurons GO:0048699 385 0.064
gtp metabolic process GO:0046039 4 0.063
regulation of rna metabolic process GO:0051252 224 0.062
regulation of signaling GO:0023051 235 0.061
regulation of multicellular organismal process GO:0051239 277 0.058
dendrite guidance GO:0070983 0 0.056
embryo development ending in birth or egg hatching GO:0009792 271 0.054
cognition GO:0050890 1 0.053
cell part morphogenesis GO:0032990 246 0.053
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.052
cellular protein catabolic process GO:0044257 4 0.051
glial cell migration GO:0008347 3 0.051
camera type eye development GO:0043010 222 0.051
ubiquitin dependent protein catabolic process GO:0006511 3 0.051
thymus development GO:0048538 10 0.050
vasculature development GO:0001944 278 0.049
cellular component movement GO:0006928 335 0.047
positive regulation of cellular component biogenesis GO:0044089 3 0.047
regulation of nervous system development GO:0051960 90 0.045
negative regulation of response to cytokine stimulus GO:0060761 2 0.045
cellular aromatic compound metabolic process GO:0006725 295 0.044
negative chemotaxis GO:0050919 1 0.044
neural crest cell development GO:0014032 62 0.043
cell projection organization GO:0030030 284 0.043
eye development GO:0001654 277 0.041
nephron epithelium morphogenesis GO:0072088 1 0.040
tube morphogenesis GO:0035239 349 0.039
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.039
adult behavior GO:0030534 2 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
renal system development GO:0072001 94 0.039
negative regulation of signaling GO:0023057 96 0.039
regulation of cellular biosynthetic process GO:0031326 245 0.038
regulation of multicellular organismal development GO:2000026 223 0.038
chordate embryonic development GO:0043009 271 0.037
positive regulation of gtp catabolic process GO:0033126 1 0.037
negative regulation of signal transduction GO:0009968 94 0.037
biosynthetic process GO:0009058 294 0.036
negative regulation of response to stimulus GO:0048585 104 0.036
forebrain cell migration GO:0021885 1 0.036
protein secretion GO:0009306 1 0.036
neuron development GO:0048666 262 0.035
actin polymerization or depolymerization GO:0008154 2 0.035
urogenital system development GO:0001655 97 0.035
larval development GO:0002164 2 0.035
cell surface receptor signaling pathway GO:0007166 325 0.034
aromatic compound biosynthetic process GO:0019438 217 0.034
embryonic skeletal system development GO:0048706 97 0.033
regulation of purine nucleotide catabolic process GO:0033121 2 0.033
positive regulation of cell cycle GO:0045787 3 0.033
intracellular estrogen receptor signaling pathway GO:0030520 3 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
establishment of localization GO:0051234 244 0.031
neuron projection guidance GO:0097485 86 0.031
system process GO:0003008 185 0.031
hematopoietic or lymphoid organ development GO:0048534 191 0.031
cell migration GO:0016477 237 0.030
heart development GO:0007507 313 0.030
nucleic acid metabolic process GO:0090304 244 0.030
regulation of metabolic process GO:0019222 359 0.030
heterocycle metabolic process GO:0046483 290 0.030
mechanosensory behavior GO:0007638 2 0.030
negative regulation of protein transport GO:0051224 3 0.030
neuron recognition GO:0008038 18 0.029
negative regulation of developmental process GO:0051093 65 0.029
membrane invagination GO:0010324 1 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
negative regulation of biological process GO:0048519 304 0.028
embryonic heart tube development GO:0035050 133 0.028
larval heart development GO:0007508 2 0.028
regulation of organelle organization GO:0033043 29 0.028
response to external stimulus GO:0009605 264 0.028
cellular response to chemical stimulus GO:0070887 157 0.028
regeneration GO:0031099 91 0.028
cytokinesis GO:0000910 3 0.027
regulation of synapse assembly GO:0051963 3 0.027
positive regulation of cellular catabolic process GO:0031331 3 0.027
axon midline choice point recognition GO:0016199 4 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
axonogenesis GO:0007409 152 0.027
small gtpase mediated signal transduction GO:0007264 8 0.027
regulation of synaptic plasticity GO:0048167 1 0.026
regulation of intracellular signal transduction GO:1902531 57 0.026
developmental pigmentation GO:0048066 48 0.026
negative regulation of cellular component organization GO:0051129 16 0.026
response to stress GO:0006950 263 0.026
cellular component morphogenesis GO:0032989 336 0.026
regulation of developmental process GO:0050793 247 0.026
retina development in camera type eye GO:0060041 146 0.026
head development GO:0060322 303 0.026
positive regulation of cellular process GO:0048522 201 0.025
kidney development GO:0001822 92 0.025
blood vessel development GO:0001568 246 0.025
branching morphogenesis of an epithelial tube GO:0048754 15 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
regulation of systemic arterial blood pressure GO:0003073 1 0.025
phagocytosis engulfment GO:0006911 1 0.025
regulation of cytokine mediated signaling pathway GO:0001959 3 0.025
developmental growth GO:0048589 166 0.024
intracellular signal transduction GO:0035556 85 0.024
blood vessel morphogenesis GO:0048514 216 0.024
ras protein signal transduction GO:0007265 7 0.024
epithelial cell development GO:0002064 42 0.024
regulation of blood circulation GO:1903522 32 0.024
pancreas development GO:0031016 84 0.024
hormone secretion GO:0046879 2 0.024
embryonic skeletal system morphogenesis GO:0048704 93 0.023
regulation of leukocyte migration GO:0002685 8 0.023
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.023
positive regulation of catabolic process GO:0009896 4 0.023
peripheral nervous system neuron differentiation GO:0048934 28 0.023
positive regulation of nucleotide catabolic process GO:0030813 1 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
transcription dna templated GO:0006351 181 0.022
regulation of response to stimulus GO:0048583 269 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
organ formation GO:0048645 17 0.022
cardiocyte differentiation GO:0035051 44 0.022
rna metabolic process GO:0016070 219 0.022
negative regulation of chromosome organization GO:2001251 1 0.022
wound healing GO:0042060 90 0.022
fin development GO:0033333 77 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
neurotransmitter secretion GO:0007269 2 0.020
skeletal system development GO:0001501 181 0.020
anatomical structure arrangement GO:0048532 2 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
nephron morphogenesis GO:0072028 2 0.020
pigmentation GO:0043473 85 0.020
microtubule organizing center organization GO:0031023 1 0.020
axon development GO:0061564 166 0.020
centrosome organization GO:0051297 1 0.020
positive regulation of gtpase activity GO:0043547 1 0.019
pronephros development GO:0048793 69 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
single organism localization GO:1902578 225 0.019
cellular response to external stimulus GO:0071496 2 0.019
regulation of heart contraction GO:0008016 32 0.019
stem cell differentiation GO:0048863 117 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
regulation of neuron differentiation GO:0045664 56 0.019
growth GO:0040007 174 0.019
regulation of mrna processing GO:0050684 3 0.019
regulation of rho protein signal transduction GO:0035023 2 0.019
cellular biosynthetic process GO:0044249 286 0.019
rna transport GO:0050658 2 0.019
electron transport chain GO:0022900 2 0.019
segmentation GO:0035282 97 0.018
nephron tubule morphogenesis GO:0072078 1 0.018
establishment of protein localization to plasma membrane GO:0090002 1 0.018
negative regulation of cytokine production GO:0001818 1 0.018
determination of left right symmetry GO:0007368 179 0.018
eye morphogenesis GO:0048592 144 0.018
protein metabolic process GO:0019538 183 0.018
cytoskeleton organization GO:0007010 96 0.017
regulation of protein polymerization GO:0032271 2 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
heart contraction GO:0060047 71 0.017
neural crest cell migration GO:0001755 42 0.017
establishment of apical basal cell polarity GO:0035089 2 0.017
protein polymerization GO:0051258 4 0.017
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.017
organic substance biosynthetic process GO:1901576 289 0.017
pigment cell differentiation GO:0050931 38 0.017
developmental growth involved in morphogenesis GO:0060560 86 0.017
nucleobase containing compound transport GO:0015931 2 0.017
negative regulation of histone modification GO:0031057 1 0.017
immune system development GO:0002520 191 0.017
cell recognition GO:0008037 19 0.017
regulation of neurogenesis GO:0050767 87 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
response to xenobiotic stimulus GO:0009410 45 0.017
negative regulation of histone methylation GO:0031061 1 0.016
localization of cell GO:0051674 244 0.016
regulation of blood pressure GO:0008217 1 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
cellular component biogenesis GO:0044085 178 0.016
negative regulation of intracellular transport GO:0032387 3 0.016
single organism organelle organization GO:1902589 199 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
regionalization GO:0003002 274 0.016
regulation of gtpase activity GO:0043087 2 0.016
negative regulation of secretion by cell GO:1903531 2 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
chemotaxis GO:0006935 104 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
skeletal system morphogenesis GO:0048705 102 0.016
negative regulation of protein complex assembly GO:0031333 1 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
positive regulation of nervous system development GO:0051962 25 0.015
atp synthesis coupled electron transport GO:0042773 1 0.015
gene expression GO:0010467 252 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of organelle assembly GO:1902115 4 0.015
regulation of ras gtpase activity GO:0032318 2 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
nucleic acid templated transcription GO:0097659 181 0.015
respiratory electron transport chain GO:0022904 2 0.015
hindbrain development GO:0030902 91 0.015
regulation of inflammatory response GO:0050727 2 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
regulation of inner ear receptor cell differentiation GO:2000980 1 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of embryonic development GO:0045995 47 0.015
determination of bilateral symmetry GO:0009855 204 0.015
regulation of mechanoreceptor differentiation GO:0045631 1 0.015
signal transduction GO:0007165 455 0.015
mrna transport GO:0051028 2 0.015
response to endogenous stimulus GO:0009719 83 0.015
negative regulation of multicellular organismal process GO:0051241 69 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
protein depolymerization GO:0051261 1 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
negative regulation of cellular process GO:0048523 283 0.014
cellular response to starvation GO:0009267 1 0.014
neuron projection development GO:0031175 180 0.014
negative regulation of neurogenesis GO:0050768 20 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
regulation of primary metabolic process GO:0080090 311 0.014
monoamine transport GO:0015844 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
leukocyte migration GO:0050900 15 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
rna localization GO:0006403 4 0.014
renal tubule morphogenesis GO:0061333 1 0.014
locomotor rhythm GO:0045475 3 0.014
melanocyte differentiation GO:0030318 26 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.013
transport GO:0006810 220 0.013
small molecule metabolic process GO:0044281 77 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
cellular amine metabolic process GO:0044106 2 0.013
branchiomotor neuron axon guidance GO:0021785 1 0.013
post embryonic organ development GO:0048569 4 0.013
nucleic acid transport GO:0050657 2 0.013
response to alkaloid GO:0043279 2 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
regulation of transcription dna templated GO:0006355 213 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
organic substance transport GO:0071702 58 0.013
positive regulation of muscle organ development GO:0048636 1 0.013
regulation of oocyte development GO:0060281 3 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
locomotion GO:0040011 313 0.013
cellular component assembly GO:0022607 170 0.013
digestive system development GO:0055123 289 0.013
centrosome duplication GO:0051298 1 0.013
ear development GO:0043583 127 0.013
inner ear development GO:0048839 126 0.013
cell morphogenesis GO:0000902 289 0.013
positive regulation of immune effector process GO:0002699 3 0.013
protein modification process GO:0036211 100 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
ventricular system development GO:0021591 12 0.013
mesodermal cell differentiation GO:0048333 21 0.013
polarized epithelial cell differentiation GO:0030859 4 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
morphogenesis of a branching epithelium GO:0061138 16 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
camera type eye morphogenesis GO:0048593 108 0.012
heart process GO:0003015 71 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
spliceosomal complex assembly GO:0000245 1 0.012
response to drug GO:0042493 3 0.012
hormone transport GO:0009914 2 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
neural crest cell differentiation GO:0014033 72 0.012
liver development GO:0001889 96 0.012
regulation of protein complex assembly GO:0043254 3 0.012
intracellular transport GO:0046907 32 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
demethylation GO:0070988 4 0.012
amine metabolic process GO:0009308 2 0.012
cell substrate adhesion GO:0031589 4 0.012
cartilage development GO:0051216 96 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
phosphorus metabolic process GO:0006793 109 0.011
regulation of synaptic vesicle transport GO:1902803 1 0.011
rna biosynthetic process GO:0032774 181 0.011
lens fiber cell development GO:0070307 3 0.011
positive regulation of cell division GO:0051781 2 0.011
epithelial cell differentiation GO:0030855 116 0.011
regulation of protein catabolic process GO:0042176 1 0.011
neuron projection morphogenesis GO:0048812 161 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
actin filament polymerization GO:0030041 2 0.011
protein k63 linked ubiquitination GO:0070534 2 0.011
artery development GO:0060840 22 0.011
purine nucleotide metabolic process GO:0006163 27 0.011
regulation of gene expression GO:0010468 265 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
glucocorticoid metabolic process GO:0008211 2 0.011
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.011
regulation of cellular component organization GO:0051128 86 0.011
anterior posterior pattern specification GO:0009952 152 0.011
neuromuscular process GO:0050905 7 0.011
regulation of cytoskeleton organization GO:0051493 11 0.011
response to wounding GO:0009611 116 0.011
regulation of transcription involved in cell fate commitment GO:0060850 1 0.011
positive regulation of gene expression GO:0010628 71 0.011
multicellular organism growth GO:0035264 4 0.011
heart morphogenesis GO:0003007 156 0.011
branching morphogenesis of a nerve GO:0048755 4 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
nerve development GO:0021675 45 0.010
entrainment of circadian clock GO:0009649 2 0.010
myeloid cell differentiation GO:0030099 86 0.010
forebrain development GO:0030900 96 0.010
lateral inhibition GO:0046331 1 0.010
protein localization to plasma membrane GO:0072659 1 0.010
medulla oblongata development GO:0021550 4 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
regulation of system process GO:0044057 40 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
pharyngeal muscle development GO:0043282 4 0.010
cellular response to organic substance GO:0071310 105 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
regulation of cell shape GO:0008360 1 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
regulation of protein metabolic process GO:0051246 56 0.010
response to growth factor GO:0070848 39 0.010
cellular protein metabolic process GO:0044267 129 0.010
macromolecule modification GO:0043412 111 0.010
positive regulation of secretion GO:0051047 1 0.010
establishment of rna localization GO:0051236 3 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
nuclear transport GO:0051169 4 0.010
negative regulation of axon guidance GO:1902668 1 0.010

dopey1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016