Danio rerio

31 known processes

tspo

translocator protein

(Aliases: zgc:103456)

tspo biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
primitive erythrocyte differentiation GO:0060319 5 0.534
erythrocyte homeostasis GO:0034101 55 0.513
cellular aromatic compound metabolic process GO:0006725 295 0.401
organic cyclic compound metabolic process GO:1901360 301 0.360
aromatic compound biosynthetic process GO:0019438 217 0.271
nitrogen compound metabolic process GO:0006807 319 0.245
homeostasis of number of cells GO:0048872 62 0.225
heterocycle metabolic process GO:0046483 290 0.205
gas transport GO:0015669 3 0.184
regulation of metabolic process GO:0019222 359 0.174
nucleobase containing compound biosynthetic process GO:0034654 205 0.170
aging GO:0007568 2 0.165
cellular modified amino acid metabolic process GO:0006575 3 0.158
cellular biosynthetic process GO:0044249 286 0.158
regulation of macromolecule metabolic process GO:0060255 317 0.147
positive regulation of biological process GO:0048518 253 0.134
cellular macromolecule metabolic process GO:0044260 391 0.130
heterocycle biosynthetic process GO:0018130 215 0.120
regulation of gene expression GO:0010468 265 0.118
transcription dna templated GO:0006351 181 0.117
immune system process GO:0002376 241 0.116
regulation of cellular metabolic process GO:0031323 320 0.110
single organism localization GO:1902578 225 0.107
cellular nitrogen compound biosynthetic process GO:0044271 218 0.105
response to drug GO:0042493 3 0.102
cellular nitrogen compound metabolic process GO:0034641 290 0.098
myeloid cell homeostasis GO:0002262 56 0.096
hematopoietic or lymphoid organ development GO:0048534 191 0.094
nucleic acid templated transcription GO:0097659 181 0.085
nucleobase containing compound metabolic process GO:0006139 274 0.078
response to metal ion GO:0010038 34 0.076
nucleic acid metabolic process GO:0090304 244 0.076
regulation of biological quality GO:0065008 263 0.075
organic substance biosynthetic process GO:1901576 289 0.075
organic cyclic compound biosynthetic process GO:1901362 223 0.074
oxoacid metabolic process GO:0043436 31 0.074
erythrocyte differentiation GO:0030218 54 0.073
rna biosynthetic process GO:0032774 181 0.073
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.070
homeostatic process GO:0042592 142 0.070
signal transduction GO:0007165 455 0.069
positive regulation of transport GO:0051050 2 0.068
regulation of macromolecule biosynthetic process GO:0010556 225 0.066
rna metabolic process GO:0016070 219 0.065
cellular amide metabolic process GO:0043603 4 0.064
regulation of cellular biosynthetic process GO:0031326 245 0.064
primitive hemopoiesis GO:0060215 27 0.062
determination of left right symmetry GO:0007368 179 0.061
gene expression GO:0010467 252 0.060
embryonic hemopoiesis GO:0035162 53 0.058
oxidation reduction process GO:0055114 41 0.056
response to chemical GO:0042221 320 0.056
larval development GO:0002164 2 0.053
response to amphetamine GO:0001975 1 0.053
erythrocyte maturation GO:0043249 8 0.053
cellular localization GO:0051641 97 0.052
macromolecule biosynthetic process GO:0009059 227 0.051
regulation of blood vessel size GO:0050880 2 0.050
embryonic organ development GO:0048568 381 0.050
regulation of blood pressure GO:0008217 1 0.049
response to stress GO:0006950 263 0.049
immune system development GO:0002520 191 0.048
response to xenobiotic stimulus GO:0009410 45 0.046
regulation of protein targeting GO:1903533 2 0.046
death GO:0016265 121 0.046
regulation of protein localization to nucleus GO:1900180 2 0.045
porphyrin containing compound biosynthetic process GO:0006779 8 0.044
lipid storage GO:0019915 1 0.044
nucleotide biosynthetic process GO:0009165 21 0.044
peptide transport GO:0015833 1 0.043
organic acid metabolic process GO:0006082 31 0.042
vasculature development GO:0001944 278 0.042
regulation of nucleocytoplasmic transport GO:0046822 2 0.041
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.041
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.040
positive regulation of secretion GO:0051047 1 0.039
positive regulation of cellular process GO:0048522 201 0.038
regulation of primary metabolic process GO:0080090 311 0.038
maintenance of location GO:0051235 4 0.037
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.037
negative regulation of protein transport GO:0051224 3 0.037
regulation of rna metabolic process GO:0051252 224 0.035
cellular response to external stimulus GO:0071496 2 0.035
single organism nuclear import GO:1902593 3 0.034
transport GO:0006810 220 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.034
establishment of localization in cell GO:0051649 77 0.034
regulation of tube size GO:0035150 2 0.033
positive regulation of rna metabolic process GO:0051254 59 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
positive regulation of secretion by cell GO:1903532 1 0.032
multicellular organismal homeostasis GO:0048871 29 0.031
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.031
nucleoside phosphate biosynthetic process GO:1901293 21 0.031
head development GO:0060322 303 0.031
protein localization to nucleus GO:0034504 3 0.031
hemopoiesis GO:0030097 183 0.030
regulation of molecular function GO:0065009 70 0.030
peptide metabolic process GO:0006518 1 0.030
long chain fatty acid metabolic process GO:0001676 1 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
regulation of multicellular organismal process GO:0051239 277 0.029
regulation of nucleic acid templated transcription GO:1903506 213 0.029
heart development GO:0007507 313 0.029
regulation of synaptic plasticity GO:0048167 1 0.029
regulation of intracellular protein transport GO:0033157 3 0.029
brain development GO:0007420 293 0.028
single organism transport GO:0044765 206 0.028
response to abiotic stimulus GO:0009628 122 0.027
regulation of biosynthetic process GO:0009889 250 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.027
protein complex localization GO:0031503 1 0.027
response to glucocorticoid GO:0051384 1 0.026
regulation of response to stimulus GO:0048583 269 0.026
endocrine process GO:0050886 2 0.026
biosynthetic process GO:0009058 294 0.026
single organism metabolic process GO:0044710 217 0.026
innate immune response GO:0045087 13 0.026
monovalent inorganic cation transport GO:0015672 42 0.025
multicellular organismal metabolic process GO:0044236 2 0.025
positive regulation of cellular biosynthetic process GO:0031328 68 0.025
organonitrogen compound biosynthetic process GO:1901566 47 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
organelle organization GO:0006996 227 0.025
hormone transport GO:0009914 2 0.025
hydrogen peroxide metabolic process GO:0042743 2 0.025
protein import into nucleus GO:0006606 3 0.025
tetrapyrrole biosynthetic process GO:0033014 8 0.025
regulation of protein transport GO:0051223 3 0.025
negative regulation of biological process GO:0048519 304 0.025
interferon beta production GO:0032608 1 0.025
hormone secretion GO:0046879 2 0.025
tetrapyrrole metabolic process GO:0033013 10 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
cofactor metabolic process GO:0051186 15 0.024
centrosome organization GO:0051297 1 0.024
cellular response to chemical stimulus GO:0070887 157 0.024
protein localization to plasma membrane GO:0072659 1 0.024
regulation of transcription dna templated GO:0006355 213 0.023
regulation of apoptotic process GO:0042981 98 0.023
positive regulation of catabolic process GO:0009896 4 0.023
regulation of signaling GO:0023051 235 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.022
negative regulation of epithelial cell proliferation GO:0050680 1 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
cellular response to biotic stimulus GO:0071216 3 0.022
secondary metabolic process GO:0019748 3 0.022
nuclear import GO:0051170 3 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
lipid homeostasis GO:0055088 3 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
neuron neuron synaptic transmission GO:0007270 1 0.022
positive regulation of muscle cell differentiation GO:0051149 1 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
carbon dioxide transport GO:0015670 3 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
multicellular organism growth GO:0035264 4 0.021
nitrogen compound transport GO:0071705 23 0.021
gtp catabolic process GO:0006184 2 0.020
response to bacterium GO:0009617 58 0.020
reactive oxygen species metabolic process GO:0072593 6 0.020
endocrine hormone secretion GO:0060986 2 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
nuclear transport GO:0051169 4 0.020
protein metabolic process GO:0019538 183 0.020
i kappab kinase nf kappab signaling GO:0007249 4 0.020
phosphorus metabolic process GO:0006793 109 0.020
protein import GO:0017038 3 0.019
small molecule metabolic process GO:0044281 77 0.019
blood vessel development GO:0001568 246 0.019
positive regulation of metabolic process GO:0009893 108 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
gtp metabolic process GO:0046039 4 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
carboxylic acid metabolic process GO:0019752 22 0.018
phagocytosis GO:0006909 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
response to transition metal nanoparticle GO:1990267 28 0.018
cellular protein metabolic process GO:0044267 129 0.018
negative regulation of protein complex assembly GO:0031333 1 0.017
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
positive regulation of immune effector process GO:0002699 3 0.017
chemical homeostasis GO:0048878 49 0.017
heme metabolic process GO:0042168 9 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
response to corticosteroid GO:0031960 1 0.017
cell death GO:0008219 121 0.017
regulation of hormone secretion GO:0046883 2 0.016
mitochondrion organization GO:0007005 4 0.016
establishment of localization GO:0051234 244 0.016
alpha amino acid metabolic process GO:1901605 3 0.016
homeostasis of number of cells within a tissue GO:0048873 4 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
heme biosynthetic process GO:0006783 8 0.016
defense response GO:0006952 47 0.016
response to antibiotic GO:0046677 1 0.016
cell proliferation GO:0008283 80 0.016
regulation of developmental process GO:0050793 247 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
porphyrin containing compound metabolic process GO:0006778 10 0.016
regulation of erythrocyte differentiation GO:0045646 2 0.016
tube morphogenesis GO:0035239 349 0.016
protein targeting to nucleus GO:0044744 3 0.016
single organism biosynthetic process GO:0044711 71 0.015
single organism organelle organization GO:1902589 199 0.015
cytokinesis GO:0000910 3 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
ear development GO:0043583 127 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
iron ion homeostasis GO:0055072 4 0.015
system process GO:0003008 185 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
response to monosaccharide GO:0034284 3 0.015
response to amine GO:0014075 1 0.015
tissue homeostasis GO:0001894 25 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
negative regulation of cell death GO:0060548 60 0.015
sensory perception of pain GO:0019233 1 0.015
regulation of metal ion transport GO:0010959 4 0.015
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
regulation of protein complex assembly GO:0043254 3 0.014
nitric oxide metabolic process GO:0046209 2 0.014
regulation of binding GO:0051098 3 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
regulation of endothelial cell proliferation GO:0001936 1 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
cellular response to radiation GO:0071478 4 0.014
guanosine containing compound catabolic process GO:1901069 2 0.013
response to inorganic substance GO:0010035 38 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
oxidative demethylation GO:0070989 1 0.013
localization of cell GO:0051674 244 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.013
myeloid cell differentiation GO:0030099 86 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
positive regulation of cell cycle GO:0045787 3 0.013
stem cell proliferation GO:0072089 4 0.013
positive regulation of dna templated transcription elongation GO:0032786 1 0.013
regulation of programmed cell death GO:0043067 101 0.013
response to endogenous stimulus GO:0009719 83 0.013
cellular protein catabolic process GO:0044257 4 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
blood vessel morphogenesis GO:0048514 216 0.013
anatomical structure homeostasis GO:0060249 36 0.012
inorganic cation transmembrane transport GO:0098662 50 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
cellular response to xenobiotic stimulus GO:0071466 35 0.012
epithelial cell differentiation GO:0030855 116 0.012
positive regulation of cell communication GO:0010647 56 0.012
mitochondrial transport GO:0006839 2 0.012
regulation of localization GO:0032879 104 0.012
regulation of cell killing GO:0031341 2 0.012
central nervous system development GO:0007417 387 0.012
multicellular organismal macromolecule metabolic process GO:0044259 2 0.012
dna templated transcription elongation GO:0006354 3 0.012
collagen metabolic process GO:0032963 2 0.011
metal ion homeostasis GO:0055065 26 0.011
membrane hyperpolarization GO:0060081 1 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
regulation of cell communication GO:0010646 232 0.011
small molecule catabolic process GO:0044282 3 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
lipid digestion GO:0044241 3 0.011
smooth muscle contraction GO:0006939 2 0.011
regulation of locomotion GO:0040012 55 0.011
regulation of lipid transport GO:0032368 4 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
purine nucleotide biosynthetic process GO:0006164 20 0.011
negative regulation of cellular process GO:0048523 283 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
sodium ion transport GO:0006814 24 0.011
locomotion GO:0040011 313 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
organelle assembly GO:0070925 110 0.011
positive regulation of striated muscle cell differentiation GO:0051155 1 0.011
organophosphate biosynthetic process GO:0090407 23 0.011
endocardial cushion formation GO:0003272 2 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
cellular component disassembly GO:0022411 1 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of membrane potential GO:0042391 23 0.011
cellular response to oxygen levels GO:0071453 1 0.011
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
multi organism process GO:0051704 134 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
macromolecule localization GO:0033036 54 0.010
xenobiotic metabolic process GO:0006805 4 0.010
neurotransmitter transport GO:0006836 2 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
purine ribonucleotide biosynthetic process GO:0009152 20 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
purine containing compound biosynthetic process GO:0072522 20 0.010
protein stabilization GO:0050821 2 0.010
muscle cell development GO:0055001 115 0.010

tspo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.044
disease of cellular proliferation DOID:14566 0 0.044
organ system cancer DOID:0050686 0 0.044
immune system disease DOID:2914 0 0.019
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.017
hematopoietic system disease DOID:74 0 0.013