Danio rerio

0 known processes

cdc34a

cell division cycle 34 homolog (S. cerevisiae) a

(Aliases: MGC55452,zgc:55452,Ube2r2)

cdc34a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transport GO:0051050 2 0.098
immune system process GO:0002376 241 0.096
regulation of filopodium assembly GO:0051489 2 0.088
meiotic nuclear division GO:0007126 4 0.083
single organism localization GO:1902578 225 0.075
organelle organization GO:0006996 227 0.073
embryo development ending in birth or egg hatching GO:0009792 271 0.069
meiotic cell cycle process GO:1903046 3 0.064
positive regulation of cellular catabolic process GO:0031331 3 0.063
larval development GO:0002164 2 0.059
programmed cell death GO:0012501 119 0.056
signal transduction GO:0007165 455 0.055
Human
aging GO:0007568 2 0.055
organelle fusion GO:0048284 3 0.053
cellular component assembly GO:0022607 170 0.053
maintenance of location GO:0051235 4 0.052
locomotion GO:0040011 313 0.052
modification dependent protein catabolic process GO:0019941 3 0.052
Human
cellular response to chemical stimulus GO:0070887 157 0.052
apoptotic process GO:0006915 116 0.052
transport GO:0006810 220 0.051
regulation of cell death GO:0010941 103 0.051
heterocycle metabolic process GO:0046483 290 0.050
protein polyubiquitination GO:0000209 4 0.049
Human
membrane fusion GO:0061025 2 0.048
single organism transport GO:0044765 206 0.047
response to bacterium GO:0009617 58 0.047
regulation of protein transport GO:0051223 3 0.044
cellular component movement GO:0006928 335 0.043
tube morphogenesis GO:0035239 349 0.042
regulation of biological quality GO:0065008 263 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.042
cortical actin cytoskeleton organization GO:0030866 1 0.042
lipid storage GO:0019915 1 0.041
regulation of cell projection assembly GO:0060491 4 0.040
regulation of programmed cell death GO:0043067 101 0.040
protein k48 linked ubiquitination GO:0070936 1 0.040
Human
xenobiotic metabolic process GO:0006805 4 0.040
morphogenesis of an epithelium GO:0002009 333 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
protein polymerization GO:0051258 4 0.039
germ line stem cell maintenance GO:0030718 2 0.038
cell migration GO:0016477 237 0.038
positive regulation of apoptotic signaling pathway GO:2001235 1 0.037
gtp catabolic process GO:0006184 2 0.037
immune system development GO:0002520 191 0.037
establishment of protein localization to organelle GO:0072594 4 0.036
guanosine containing compound catabolic process GO:1901069 2 0.036
protein import into nucleus GO:0006606 3 0.036
gtp metabolic process GO:0046039 4 0.035
protein complex localization GO:0031503 1 0.035
single organism organelle organization GO:1902589 199 0.034
embryonic organ development GO:0048568 381 0.033
response to other organism GO:0051707 97 0.033
single organism nuclear import GO:1902593 3 0.033
cell death GO:0008219 121 0.033
regulation of cellular metabolic process GO:0031323 320 0.033
guanosine containing compound metabolic process GO:1901068 4 0.032
meiosis i GO:0007127 1 0.032
cytokinesis GO:0000910 3 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
nuclear import GO:0051170 3 0.032
cell cycle g1 s phase transition GO:0044843 1 0.032
nucleocytoplasmic transport GO:0006913 4 0.031
eye development GO:0001654 277 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
protein targeting to nucleus GO:0044744 3 0.031
vasculature development GO:0001944 278 0.031
response to biotic stimulus GO:0009607 97 0.031
hemopoiesis GO:0030097 183 0.031
gland development GO:0048732 143 0.031
central nervous system development GO:0007417 387 0.031
cell motility GO:0048870 244 0.030
cortical cytoskeleton organization GO:0030865 1 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
stem cell maintenance GO:0019827 4 0.030
protein localization to nucleus GO:0034504 3 0.030
positive regulation of glucose transport GO:0010828 1 0.030
growth GO:0040007 174 0.029
establishment of localization GO:0051234 244 0.029
negative regulation of biological process GO:0048519 304 0.029
Human
exocytosis GO:0006887 1 0.029
nuclear transport GO:0051169 4 0.029
regulation of apoptotic process GO:0042981 98 0.029
regulation of wound healing GO:0061041 2 0.029
death GO:0016265 121 0.028
regulation of intracellular protein transport GO:0033157 3 0.028
endosomal transport GO:0016197 2 0.028
single organism membrane fusion GO:0044801 2 0.027
response to external stimulus GO:0009605 264 0.027
stem cell proliferation GO:0072089 4 0.027
cellular component biogenesis GO:0044085 178 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.026
stem cell division GO:0017145 1 0.026
regulation of biosynthetic process GO:0009889 250 0.026
nuclear migration GO:0007097 3 0.026
nitrogen compound metabolic process GO:0006807 319 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
regulation of synapse assembly GO:0051963 3 0.025
mitochondrion organization GO:0007005 4 0.025
regulation of cell communication GO:0010646 232 0.025
Human
g1 s transition of mitotic cell cycle GO:0000082 1 0.025
heart development GO:0007507 313 0.024
glial cell migration GO:0008347 3 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
homeostatic process GO:0042592 142 0.023
organic substance biosynthetic process GO:1901576 289 0.023
positive regulation of cell cycle GO:0045787 3 0.023
regulation of cytokine production GO:0001817 3 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
developmental growth GO:0048589 166 0.023
retina development in camera type eye GO:0060041 146 0.022
response to chemical GO:0042221 320 0.022
positive regulation of catabolic process GO:0009896 4 0.022
peptide transport GO:0015833 1 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
Human
muscle structure development GO:0061061 196 0.021
ameboidal type cell migration GO:0001667 143 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
regulation of reproductive process GO:2000241 4 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
Human
brain development GO:0007420 293 0.021
regulation of protein targeting GO:1903533 2 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
synaptic vesicle localization GO:0097479 1 0.021
compound eye development GO:0048749 2 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
digestive system development GO:0055123 289 0.021
neuroblast proliferation GO:0007405 2 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
regulation of glucose transport GO:0010827 1 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
response to stress GO:0006950 263 0.020
biosynthetic process GO:0009058 294 0.020
recombinational repair GO:0000725 1 0.020
nucleic acid templated transcription GO:0097659 181 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
muscle cell differentiation GO:0042692 139 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
Human
melanin metabolic process GO:0006582 2 0.020
meiotic chromosome segregation GO:0045132 3 0.020
cellular ketone metabolic process GO:0042180 11 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
protein localization to plasma membrane GO:0072659 1 0.020
regulation of protein complex assembly GO:0043254 3 0.019
regulation of synapse organization GO:0050807 3 0.019
adult behavior GO:0030534 2 0.019
regulation of developmental process GO:0050793 247 0.019
negative regulation of response to stimulus GO:0048585 104 0.019
Human
amine metabolic process GO:0009308 2 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
maintenance of cell polarity GO:0030011 5 0.019
actin cytoskeleton organization GO:0030036 63 0.019
secondary metabolic process GO:0019748 3 0.019
phagocytosis GO:0006909 3 0.019
cytokinetic process GO:0032506 2 0.019
cellular component maintenance GO:0043954 3 0.018
actin filament based process GO:0030029 64 0.018
cellular amine metabolic process GO:0044106 2 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
striated muscle cell differentiation GO:0051146 129 0.018
apoptotic process involved in development GO:1902742 2 0.018
energy reserve metabolic process GO:0006112 2 0.018
positive regulation of biological process GO:0048518 253 0.018
localization of cell GO:0051674 244 0.018
negative regulation of cell communication GO:0010648 96 0.018
Human
establishment of synaptic vesicle localization GO:0097480 1 0.018
negative regulation of mapk cascade GO:0043409 4 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
negative regulation of apoptotic process GO:0043066 55 0.018
glucose import GO:0046323 2 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of protein polymerization GO:0032271 2 0.018
regulation of cell shape GO:0008360 1 0.017
oxoacid metabolic process GO:0043436 31 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
head development GO:0060322 303 0.017
cellular biosynthetic process GO:0044249 286 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
dna biosynthetic process GO:0071897 3 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
camera type eye development GO:0043010 222 0.017
regulation of binding GO:0051098 3 0.017
regulation of signal transduction GO:0009966 225 0.017
Human
regulation of multicellular organism growth GO:0040014 4 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
adherens junction organization GO:0034332 4 0.016
rna metabolic process GO:0016070 219 0.016
regulation of localization GO:0032879 104 0.016
multi organism process GO:0051704 134 0.016
cell projection assembly GO:0030031 64 0.016
regulation of protein catabolic process GO:0042176 1 0.016
synaptic vesicle endocytosis GO:0048488 1 0.016
phosphorus metabolic process GO:0006793 109 0.016
regulation of protein localization to plasma membrane GO:1903076 1 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
tissue regeneration GO:0042246 74 0.016
melanosome transport GO:0032402 19 0.016
defense response GO:0006952 47 0.016
chemosensory behavior GO:0007635 1 0.016
signal transduction in absence of ligand GO:0038034 1 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
eye morphogenesis GO:0048592 144 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
pole plasm assembly GO:0007315 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
protein homooligomerization GO:0051260 3 0.015
gene expression GO:0010467 252 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
digestive tract morphogenesis GO:0048546 231 0.015
response to organic substance GO:0010033 153 0.015
cellular response to nutrient levels GO:0031669 2 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
negative regulation of signal transduction GO:0009968 94 0.015
Human
antimicrobial humoral response GO:0019730 2 0.015
synaptic vesicle transport GO:0048489 1 0.015
adherens junction maintenance GO:0034334 2 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
angiogenesis GO:0001525 158 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
transcription dna templated GO:0006351 181 0.015
cytoplasm organization GO:0007028 4 0.015
positive regulation of cellular process GO:0048522 201 0.015
neutrophil mediated immunity GO:0002446 1 0.014
autophagy GO:0006914 4 0.014
positive regulation of secretion GO:0051047 1 0.014
nucleic acid metabolic process GO:0090304 244 0.014
cell morphogenesis GO:0000902 289 0.014
response to glucose GO:0009749 3 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
cellular response to xenobiotic stimulus GO:0071466 35 0.014
regulation of response to stimulus GO:0048583 269 0.014
Human
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
response to drug GO:0042493 3 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
cellular protein catabolic process GO:0044257 4 0.014
Human
negative regulation of nuclear division GO:0051784 3 0.014
negative regulation of cellular process GO:0048523 283 0.014
Human
cellular response to external stimulus GO:0071496 2 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
Human
synaptic vesicle recycling GO:0036465 1 0.014
digestive tract development GO:0048565 265 0.014
developmental programmed cell death GO:0010623 4 0.014
cell projection organization GO:0030030 284 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
skeletal system morphogenesis GO:0048705 102 0.013
negative regulation of reproductive process GO:2000242 3 0.013
cell junction maintenance GO:0034331 2 0.013
cellular component morphogenesis GO:0032989 336 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
atp catabolic process GO:0006200 4 0.013
leukocyte proliferation GO:0070661 1 0.013
stem cell differentiation GO:0048863 117 0.013
sensory organ morphogenesis GO:0090596 200 0.013
cytoskeleton organization GO:0007010 96 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
regulation of primary metabolic process GO:0080090 311 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
negative regulation of cell death GO:0060548 60 0.013
female meiotic division GO:0007143 2 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
response to nutrient GO:0007584 3 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
generation of neurons GO:0048699 385 0.013
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.013
microtubule based process GO:0007017 60 0.013
regulation of metabolic process GO:0019222 359 0.013
response to wounding GO:0009611 116 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
regulation of synaptic plasticity GO:0048167 1 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
centrosome organization GO:0051297 1 0.012
protein secretion GO:0009306 1 0.012
cell cycle GO:0007049 93 0.012
cellular response to starvation GO:0009267 1 0.012
rna biosynthetic process GO:0032774 181 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
protein complex subunit organization GO:0071822 46 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
Human
single organism metabolic process GO:0044710 217 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
multicellular organism growth GO:0035264 4 0.012
establishment of localization in cell GO:0051649 77 0.012
lysosomal transport GO:0007041 2 0.012
wound healing GO:0042060 90 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
actin filament polymerization GO:0030041 2 0.012
b cell activation GO:0042113 2 0.012
trabecula morphogenesis GO:0061383 2 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
Human
centrosome cycle GO:0007098 1 0.012
positive regulation of glucose import GO:0046326 1 0.012
single fertilization GO:0007338 3 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
organic acid metabolic process GO:0006082 31 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.012
fertilization GO:0009566 3 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.011
organelle assembly GO:0070925 110 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
myeloid cell differentiation GO:0030099 86 0.011
response to external biotic stimulus GO:0043207 97 0.011
protein modification process GO:0036211 100 0.011
Human Mouse
regulation of transporter activity GO:0032409 2 0.011
ion transport GO:0006811 114 0.011
gastrulation GO:0007369 208 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
striated muscle cell development GO:0055002 108 0.011
multi organism cellular process GO:0044764 2 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
organic substance transport GO:0071702 58 0.011
mitotic recombination GO:0006312 2 0.011
regulation of synaptic vesicle transport GO:1902803 1 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
pigmentation GO:0043473 85 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
negative regulation of cytokine production GO:0001818 1 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
positive regulation of metabolic process GO:0009893 108 0.011
intracellular signal transduction GO:0035556 85 0.011
Human
hepaticobiliary system development GO:0061008 98 0.011
golgi vesicle transport GO:0048193 3 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
positive regulation of ras protein signal transduction GO:0046579 1 0.011
positive regulation of cell division GO:0051781 2 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
regulation of organ growth GO:0046620 3 0.011
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
cellular extravasation GO:0045123 1 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
positive regulation of immune effector process GO:0002699 3 0.011
renal tubule morphogenesis GO:0061333 1 0.011
membrane invagination GO:0010324 1 0.010
small molecule metabolic process GO:0044281 77 0.010
protein import GO:0017038 3 0.010
camera type eye morphogenesis GO:0048593 108 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
cellular pigmentation GO:0033059 30 0.010
positive regulation of exocytosis GO:0045921 1 0.010
segmentation GO:0035282 97 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
mitotic cell cycle GO:0000278 64 0.010
spermatid development GO:0007286 2 0.010
negative regulation of signaling GO:0023057 96 0.010
Human
cognition GO:0050890 1 0.010
cell aging GO:0007569 2 0.010
neuron development GO:0048666 262 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
regionalization GO:0003002 274 0.010
medulla oblongata development GO:0021550 4 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
chemotaxis GO:0006935 104 0.010

cdc34a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
immune system disease DOID:2914 0 0.011