Danio rerio

0 known processes

ube2d1

ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)

(Aliases: zgc:73096,wu:fc16h06)

ube2d1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 3 0.613
Human Yeast
signal transduction GO:0007165 455 0.524
ubiquitin dependent protein catabolic process GO:0006511 3 0.463
Human Yeast
regulation of protein ubiquitination GO:0031396 3 0.433
Human
cellular protein catabolic process GO:0044257 4 0.425
Human Yeast
modification dependent protein catabolic process GO:0019941 3 0.356
Human Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.318
regulation of metabolic process GO:0019222 359 0.272
Human
organelle fusion GO:0048284 3 0.260
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.255
Human
positive regulation of exocytosis GO:0045921 1 0.245
cellular macromolecule metabolic process GO:0044260 391 0.201
Human Yeast Mouse Rat
regulation of signal transduction GO:0009966 225 0.191
negative regulation of biological process GO:0048519 304 0.191
negative regulation of cellular process GO:0048523 283 0.190
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.179
spermatid differentiation GO:0048515 2 0.155
negative regulation of signal transduction GO:0009968 94 0.154
positive regulation of transport GO:0051050 2 0.143
aromatic compound biosynthetic process GO:0019438 217 0.135
establishment of localization GO:0051234 244 0.127
regulation of cellular metabolic process GO:0031323 320 0.126
Human
regulation of rna biosynthetic process GO:2001141 213 0.125
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.122
Human Yeast
positive regulation of cellular process GO:0048522 201 0.118
Human
single organism localization GO:1902578 225 0.117
larval development GO:0002164 2 0.116
gene expression GO:0010467 252 0.114
cellular response to extracellular stimulus GO:0031668 2 0.112
establishment of localization in cell GO:0051649 77 0.107
regulation of meiotic cell cycle GO:0051445 1 0.107
organic cyclic compound metabolic process GO:1901360 301 0.106
skeletal muscle organ development GO:0060538 78 0.104
aging GO:0007568 2 0.100
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.099
nucleobase containing compound biosynthetic process GO:0034654 205 0.099
compound eye development GO:0048749 2 0.098
regulation of signaling GO:0023051 235 0.098
positive regulation of cellular catabolic process GO:0031331 3 0.096
regulation of purine nucleotide catabolic process GO:0033121 2 0.095
single organism transport GO:0044765 206 0.094
transcription dna templated GO:0006351 181 0.092
endosomal transport GO:0016197 2 0.091
nuclear transport GO:0051169 4 0.088
positive regulation of nucleoside metabolic process GO:0045979 1 0.087
regulation of macromolecule biosynthetic process GO:0010556 225 0.087
regulation of cell communication GO:0010646 232 0.087
cytoskeleton organization GO:0007010 96 0.086
maintenance of location GO:0051235 4 0.084
cellular biosynthetic process GO:0044249 286 0.082
spermatid development GO:0007286 2 0.082
regulation of binding GO:0051098 3 0.080
nucleic acid templated transcription GO:0097659 181 0.080
regulation of nucleotide catabolic process GO:0030811 2 0.080
protein polyubiquitination GO:0000209 4 0.080
Human Yeast Mouse
cell surface receptor signaling pathway GO:0007166 325 0.080
regulation of cellular protein metabolic process GO:0032268 52 0.080
Human
chordate embryonic development GO:0043009 271 0.080
rna metabolic process GO:0016070 219 0.079
cellular response to stress GO:0033554 62 0.078
Yeast
apoptotic process GO:0006915 116 0.076
regulation of protein complex assembly GO:0043254 3 0.076
negative regulation of cell communication GO:0010648 96 0.075
macromolecule catabolic process GO:0009057 15 0.074
Human Yeast
cellular response to starvation GO:0009267 1 0.073
positive regulation of catabolic process GO:0009896 4 0.073
sensory organ development GO:0007423 393 0.069
cellular response to external stimulus GO:0071496 2 0.069
cellular protein metabolic process GO:0044267 129 0.068
Human Yeast Mouse Rat
positive regulation of macromolecule metabolic process GO:0010604 93 0.068
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.068
interspecies interaction between organisms GO:0044419 4 0.068
positive regulation of cellular metabolic process GO:0031325 94 0.067
Human
heterocycle biosynthetic process GO:0018130 215 0.063
negative regulation of response to stimulus GO:0048585 104 0.063
positive regulation of biological process GO:0048518 253 0.062
Human
regulation of nucleic acid templated transcription GO:1903506 213 0.062
single organism membrane fusion GO:0044801 2 0.060
negative regulation of cellular metabolic process GO:0031324 77 0.059
negative regulation of signaling GO:0023057 96 0.059
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.059
regulation of protein metabolic process GO:0051246 56 0.058
Human
regulation of biosynthetic process GO:0009889 250 0.058
growth GO:0040007 174 0.056
establishment of protein localization to organelle GO:0072594 4 0.055
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.055
intracellular signal transduction GO:0035556 85 0.055
regulation of biological quality GO:0065008 263 0.055
intracellular transport GO:0046907 32 0.055
regulation of nucleoside metabolic process GO:0009118 2 0.054
regulation of cellular biosynthetic process GO:0031326 245 0.053
positive regulation of gtp catabolic process GO:0033126 1 0.053
regulation of transcription dna templated GO:0006355 213 0.053
negative regulation of gene expression GO:0010629 65 0.052
negative regulation of protein transport GO:0051224 3 0.051
single organism organelle organization GO:1902589 199 0.051
regulation of cytoplasmic transport GO:1903649 4 0.051
viral process GO:0016032 1 0.051
regulation of macromolecule metabolic process GO:0060255 317 0.050
Human
i kappab kinase nf kappab signaling GO:0007249 4 0.049
nitrogen compound metabolic process GO:0006807 319 0.049
cellular nitrogen compound biosynthetic process GO:0044271 218 0.048
regulation of rna metabolic process GO:0051252 224 0.047
multi organism process GO:0051704 134 0.045
protein metabolic process GO:0019538 183 0.045
Human Yeast Mouse Rat
cellular response to nutrient levels GO:0031669 2 0.045
eye development GO:0001654 277 0.044
positive regulation of secretion by cell GO:1903532 1 0.044
single organism metabolic process GO:0044710 217 0.044
protein localization to nucleus GO:0034504 3 0.043
positive regulation of map kinase activity GO:0043406 3 0.043
death GO:0016265 121 0.043
actin filament based process GO:0030029 64 0.042
heterocycle metabolic process GO:0046483 290 0.042
nucleic acid metabolic process GO:0090304 244 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.042
regulation of protein transport GO:0051223 3 0.042
regulation of rho protein signal transduction GO:0035023 2 0.042
nucleocytoplasmic transport GO:0006913 4 0.041
extrinsic apoptotic signaling pathway GO:0097191 3 0.041
mitochondrion organization GO:0007005 4 0.041
organelle organization GO:0006996 227 0.040
macromolecule biosynthetic process GO:0009059 227 0.040
enzyme linked receptor protein signaling pathway GO:0007167 106 0.040
positive regulation of nucleotide catabolic process GO:0030813 1 0.040
meiotic nuclear division GO:0007126 4 0.040
response to drug GO:0042493 3 0.039
regulation of gene expression GO:0010468 265 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.039
cellular localization GO:0051641 97 0.039
biosynthetic process GO:0009058 294 0.039
lipid storage GO:0019915 1 0.039
embryonic organ development GO:0048568 381 0.039
cell death GO:0008219 121 0.038
nucleobase containing compound metabolic process GO:0006139 274 0.037
cell morphogenesis GO:0000902 289 0.037
cellular protein modification process GO:0006464 100 0.037
Human Yeast Mouse Rat
transport GO:0006810 220 0.036
proteasomal protein catabolic process GO:0010498 2 0.036
positive regulation of cell cycle GO:0045787 3 0.035
protein import into nucleus GO:0006606 3 0.035
positive regulation of secretion GO:0051047 1 0.035
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.034
peptide transport GO:0015833 1 0.034
protein k48 linked ubiquitination GO:0070936 1 0.034
Human
regulation of cell death GO:0010941 103 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
cellular component movement GO:0006928 335 0.033
catabolic process GO:0009056 32 0.033
Human Yeast
regulation of protein targeting GO:1903533 2 0.033
regulation of intracellular signal transduction GO:1902531 57 0.033
single organism nuclear import GO:1902593 3 0.033
regulation of cell activation GO:0050865 1 0.032
positive regulation of signaling GO:0023056 56 0.032
positive regulation of metabolic process GO:0009893 108 0.032
Human
regulation of multicellular organismal process GO:0051239 277 0.031
multi organism cellular process GO:0044764 2 0.031
glial cell migration GO:0008347 3 0.031
organic substance catabolic process GO:1901575 28 0.031
Human Yeast
mesenchymal cell development GO:0014031 78 0.031
meiotic chromosome segregation GO:0045132 3 0.031
regulation of multicellular organismal development GO:2000026 223 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
regulation of intracellular protein transport GO:0033157 3 0.030
morphogenesis of an epithelium GO:0002009 333 0.030
positive regulation of response to stimulus GO:0048584 80 0.030
macromolecule modification GO:0043412 111 0.029
Human Yeast Mouse Rat
chromosome organization involved in meiosis GO:0070192 1 0.029
epidermal cell differentiation GO:0009913 36 0.028
positive regulation of signal transduction GO:0009967 56 0.028
embryonic cranial skeleton morphogenesis GO:0048701 90 0.028
regulation of response to stimulus GO:0048583 269 0.028
regulation of developmental process GO:0050793 247 0.028
cellular response to chemical stimulus GO:0070887 157 0.027
regulation of protein catabolic process GO:0042176 1 0.027
neural crest cell migration GO:0001755 42 0.027
positive regulation of wound healing GO:0090303 1 0.027
regulation of apoptotic process GO:0042981 98 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.027
regulation of circadian rhythm GO:0042752 4 0.026
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.026
negative regulation of cytoplasmic transport GO:1903650 2 0.026
regulation of synaptic plasticity GO:0048167 1 0.026
protein targeting to nucleus GO:0044744 3 0.026
regulation of protein import into nucleus GO:0042306 2 0.026
protein import GO:0017038 3 0.025
rna biosynthetic process GO:0032774 181 0.025
response to chemical GO:0042221 320 0.025
regulation of metal ion transport GO:0010959 4 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
regulation of exocytosis GO:0017157 1 0.025
organic substance biosynthetic process GO:1901576 289 0.025
locomotion GO:0040011 313 0.025
cellular component morphogenesis GO:0032989 336 0.025
regulation of proteolysis GO:0030162 24 0.025
programmed cell death GO:0012501 119 0.024
regulation of hormone secretion GO:0046883 2 0.024
regulation of cell differentiation GO:0045595 142 0.024
cellular response to xenobiotic stimulus GO:0071466 35 0.024
nuclear import GO:0051170 3 0.024
regulation of molecular function GO:0065009 70 0.024
cortical actin cytoskeleton organization GO:0030866 1 0.024
positive regulation of catalytic activity GO:0043085 25 0.024
regulation of cell shape GO:0008360 1 0.023
generation of neurons GO:0048699 385 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
protein secretion GO:0009306 1 0.023
macromolecule localization GO:0033036 54 0.023
carbohydrate biosynthetic process GO:0016051 1 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
digestive system development GO:0055123 289 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
actin cytoskeleton organization GO:0030036 63 0.022
regulation of phosphorus metabolic process GO:0051174 43 0.022
immune system process GO:0002376 241 0.022
gtp metabolic process GO:0046039 4 0.021
negative regulation of apoptotic process GO:0043066 55 0.021
regulation of cytokine production GO:0001817 3 0.021
proteolysis GO:0006508 38 0.021
Human Yeast
regulation of wound healing GO:0061041 2 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
negative regulation of cell death GO:0060548 60 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
hemopoiesis GO:0030097 183 0.020
organic substance transport GO:0071702 58 0.020
macroautophagy GO:0016236 1 0.020
regulation of programmed cell death GO:0043067 101 0.020
cell proliferation GO:0008283 80 0.020
cell projection organization GO:0030030 284 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
exocytosis GO:0006887 1 0.020
muscle organ development GO:0007517 101 0.020
immune system development GO:0002520 191 0.020
response to external stimulus GO:0009605 264 0.020
regulation of localization GO:0032879 104 0.020
system process GO:0003008 185 0.020
regulation of primary metabolic process GO:0080090 311 0.020
Human
positive regulation of immune effector process GO:0002699 3 0.020
neural crest cell development GO:0014032 62 0.019
regulation of muscle contraction GO:0006937 3 0.019
meiosis i GO:0007127 1 0.019
embryonic skeletal system morphogenesis GO:0048704 93 0.019
single organism intracellular transport GO:1902582 25 0.019
regulation of purine nucleotide metabolic process GO:1900542 17 0.019
organelle localization GO:0051640 49 0.019
regulation of cell projection assembly GO:0060491 4 0.019
heart development GO:0007507 313 0.019
regulation of tube size GO:0035150 2 0.019
posttranscriptional regulation of gene expression GO:0010608 14 0.019
phagocytosis GO:0006909 3 0.019
developmental growth GO:0048589 166 0.018
protein catabolic process GO:0030163 7 0.018
Human Yeast
cellular aromatic compound metabolic process GO:0006725 295 0.018
notch signaling pathway GO:0007219 35 0.018
regulation of cellular protein catabolic process GO:1903362 1 0.018
regulation of anatomical structure size GO:0090066 33 0.018
muscle structure development GO:0061061 196 0.018
central nervous system development GO:0007417 387 0.018
single organism cellular localization GO:1902580 46 0.018
head development GO:0060322 303 0.018
positive regulation of proteolysis GO:0045862 10 0.018
cellular response to organic cyclic compound GO:0071407 38 0.018
localization of cell GO:0051674 244 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
microtubule based process GO:0007017 60 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
membrane fusion GO:0061025 2 0.017
regulation of mrna processing GO:0050684 3 0.017
response to wounding GO:0009611 116 0.017
cellular catabolic process GO:0044248 27 0.017
Human Yeast
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
regulation of cellular component size GO:0032535 30 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
positive regulation of protein metabolic process GO:0051247 23 0.016
Human
cellular amine metabolic process GO:0044106 2 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
blood vessel development GO:0001568 246 0.016
multicellular organism growth GO:0035264 4 0.016
synaptic vesicle transport GO:0048489 1 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
regulation of hydrolase activity GO:0051336 28 0.016
negative regulation of metabolic process GO:0009892 86 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of notch signaling pathway GO:0008593 16 0.016
mitotic cell cycle process GO:1903047 48 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
mesenchyme development GO:0060485 127 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
eye morphogenesis GO:0048592 144 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
chromosome localization GO:0050000 2 0.015
regulation of transport GO:0051049 45 0.015
brain development GO:0007420 293 0.015
regulation of cellular component organization GO:0051128 86 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
proximal distal pattern formation GO:0009954 1 0.015
meiotic cell cycle process GO:1903046 3 0.015
skeletal muscle tissue development GO:0007519 67 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
positive regulation of multi organism process GO:0043902 3 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
autophagy GO:0006914 4 0.014
response to xenobiotic stimulus GO:0009410 45 0.014
protein localization GO:0008104 40 0.014
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.014
striated muscle cell differentiation GO:0051146 129 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
gastrulation GO:0007369 208 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.013
cell part morphogenesis GO:0032990 246 0.013
axis specification GO:0009798 43 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
gtp catabolic process GO:0006184 2 0.013
protein phosphorylation GO:0006468 47 0.013
atp catabolic process GO:0006200 4 0.013
cellular response to organic substance GO:0071310 105 0.013
hormone secretion GO:0046879 2 0.013
regulation of lipid transport GO:0032368 4 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
response to corticosteroid GO:0031960 1 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
response to uv GO:0009411 3 0.012
regulation of peptidase activity GO:0052547 23 0.012
synaptic vesicle localization GO:0097479 1 0.012
negative regulation of multi organism process GO:0043901 3 0.012
regulation of nucleotide metabolic process GO:0006140 17 0.012
embryonic skeletal system development GO:0048706 97 0.012
response to hexose GO:0009746 3 0.012
small molecule metabolic process GO:0044281 77 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
neuron differentiation GO:0030182 353 0.012
response to stress GO:0006950 263 0.012
Yeast
striated muscle cell development GO:0055002 108 0.012
positive regulation of cell communication GO:0010647 56 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
cell projection morphogenesis GO:0048858 244 0.012
stem cell maintenance GO:0019827 4 0.012
peptidyl serine modification GO:0018209 2 0.012
neurotransmitter secretion GO:0007269 2 0.012
centrosome organization GO:0051297 1 0.011
axon development GO:0061564 166 0.011
regulation of reproductive process GO:2000241 4 0.011
phosphorus metabolic process GO:0006793 109 0.011
organophosphate metabolic process GO:0019637 37 0.011
positive regulation of cytokine production GO:0001819 2 0.011
ameboidal type cell migration GO:0001667 143 0.011
oxoacid metabolic process GO:0043436 31 0.011
positive regulation of cell death GO:0010942 29 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
mitochondrial transport GO:0006839 2 0.011
gamete generation GO:0007276 33 0.011
somatic muscle development GO:0007525 4 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
receptor metabolic process GO:0043112 6 0.011
germ cell development GO:0007281 22 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
positive regulation of hydrolase activity GO:0051345 13 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
dna templated transcription initiation GO:0006352 1 0.011
rhombomere 6 development GO:0021572 4 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
cellular response to light stimulus GO:0071482 4 0.010
appendage development GO:0048736 80 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
response to lipid GO:0033993 60 0.010
heart morphogenesis GO:0003007 156 0.010
regulation of catalytic activity GO:0050790 55 0.010
mitotic cell cycle GO:0000278 64 0.010
developmental pigmentation GO:0048066 48 0.010
tube morphogenesis GO:0035239 349 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
recombinational repair GO:0000725 1 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
double strand break repair via homologous recombination GO:0000724 1 0.010
response to organic cyclic compound GO:0014070 51 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
regulation of calcium ion transport GO:0051924 2 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
protein complex localization GO:0031503 1 0.010
carbohydrate homeostasis GO:0033500 1 0.010
energy reserve metabolic process GO:0006112 2 0.010
tube closure GO:0060606 1 0.010
cellular response to topologically incorrect protein GO:0035967 2 0.010
cellular component disassembly GO:0022411 1 0.010

ube2d1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
musculoskeletal system disease DOID:17 0 0.010