Danio rerio

0 known processes

gpt2

glutamic pyruvate transaminase (alanine aminotransferase) 2

(Aliases: im:7150662,MGC165657,zgc:165657,sb:cb580)

gpt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule biosynthetic process GO:0034645 224 0.098
tube morphogenesis GO:0035239 349 0.086
negative regulation of cell communication GO:0010648 96 0.062
organic cyclic compound metabolic process GO:1901360 301 0.061
neuron projection morphogenesis GO:0048812 161 0.060
signal transduction GO:0007165 455 0.058
cellular response to external stimulus GO:0071496 2 0.058
cellular nitrogen compound metabolic process GO:0034641 290 0.057
cytokinesis GO:0000910 3 0.054
rna modification GO:0009451 2 0.053
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.052
positive regulation of transport GO:0051050 2 0.050
neuron development GO:0048666 262 0.048
cell surface receptor signaling pathway GO:0007166 325 0.048
meiotic nuclear division GO:0007126 4 0.047
cell morphogenesis involved in differentiation GO:0000904 195 0.047
nitrogen compound metabolic process GO:0006807 319 0.046
organelle organization GO:0006996 227 0.046
regulation of signaling GO:0023051 235 0.045
regulation of signal transduction GO:0009966 225 0.045
heterocycle metabolic process GO:0046483 290 0.045
regulation of cell communication GO:0010646 232 0.045
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.045
negative regulation of response to stimulus GO:0048585 104 0.044
protein metabolic process GO:0019538 183 0.043
phagocytosis GO:0006909 3 0.042
regulation of establishment of protein localization GO:0070201 4 0.042
single organism localization GO:1902578 225 0.042
cellular macromolecule metabolic process GO:0044260 391 0.041
cellular component morphogenesis GO:0032989 336 0.041
regulation of response to stimulus GO:0048583 269 0.040
maintenance of location GO:0051235 4 0.039
negative regulation of signaling GO:0023057 96 0.039
death GO:0016265 121 0.038
response to ketone GO:1901654 1 0.038
regulation of cellular metabolic process GO:0031323 320 0.038
negative regulation of signal transduction GO:0009968 94 0.038
rna metabolic process GO:0016070 219 0.037
gtp metabolic process GO:0046039 4 0.036
regulation of cell projection assembly GO:0060491 4 0.034
gastrulation GO:0007369 208 0.034
nucleic acid metabolic process GO:0090304 244 0.034
regulation of gene expression GO:0010468 265 0.033
negative regulation of cellular process GO:0048523 283 0.033
fatty acid biosynthetic process GO:0006633 4 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.031
cell morphogenesis GO:0000902 289 0.031
regulation of protein transport GO:0051223 3 0.031
single organism metabolic process GO:0044710 217 0.031
macromolecule biosynthetic process GO:0009059 227 0.030
gtp catabolic process GO:0006184 2 0.030
cell part morphogenesis GO:0032990 246 0.030
single organism membrane fusion GO:0044801 2 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
cellular aromatic compound metabolic process GO:0006725 295 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
organic substance biosynthetic process GO:1901576 289 0.029
microtubule based process GO:0007017 60 0.029
axonogenesis GO:0007409 152 0.029
very long chain fatty acid metabolic process GO:0000038 4 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
cell death GO:0008219 121 0.028
cellular protein metabolic process GO:0044267 129 0.027
regulation of metabolic process GO:0019222 359 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
Worm
regulation of primary metabolic process GO:0080090 311 0.027
modification dependent protein catabolic process GO:0019941 3 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
positive regulation of translation GO:0045727 1 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
regulation of filopodium assembly GO:0051489 2 0.026
protein n linked glycosylation GO:0006487 1 0.026
mitochondrion organization GO:0007005 4 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.025
axon development GO:0061564 166 0.025
cell projection morphogenesis GO:0048858 244 0.025
negative regulation of ras protein signal transduction GO:0046580 1 0.025
transcription dna templated GO:0006351 181 0.025
regulation of response to nutrient levels GO:0032107 1 0.025
stem cell division GO:0017145 1 0.025
eye development GO:0001654 277 0.024
cellular protein catabolic process GO:0044257 4 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
meiosis i GO:0007127 1 0.024
cell motility GO:0048870 244 0.024
cellular biosynthetic process GO:0044249 286 0.024
cellular component disassembly GO:0022411 1 0.024
cell fate commitment GO:0045165 99 0.024
protein modification process GO:0036211 100 0.023
response to nutrient GO:0007584 3 0.023
cytoskeleton organization GO:0007010 96 0.023
response to stress GO:0006950 263 0.023
biosynthetic process GO:0009058 294 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
positive regulation of catabolic process GO:0009896 4 0.023
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
sensory organ development GO:0007423 393 0.022
regulation of cell substrate adhesion GO:0010810 1 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
oocyte maturation GO:0001556 4 0.022
peptidyl serine phosphorylation GO:0018105 1 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
digestive tract morphogenesis GO:0048546 231 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
neuron differentiation GO:0030182 353 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
cell projection organization GO:0030030 284 0.022
guanosine containing compound catabolic process GO:1901069 2 0.021
larval development GO:0002164 2 0.021
Worm
regulation of localization GO:0032879 104 0.021
negative regulation of kinase activity GO:0033673 4 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
androgen metabolic process GO:0008209 2 0.020
cellular component biogenesis GO:0044085 178 0.020
cellular protein modification process GO:0006464 100 0.020
oxoacid metabolic process GO:0043436 31 0.020
membrane lipid biosynthetic process GO:0046467 2 0.020
meiotic cell cycle process GO:1903046 3 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
protein complex subunit organization GO:0071822 46 0.020
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
embryonic organ development GO:0048568 381 0.019
myeloid cell differentiation GO:0030099 86 0.019
regulation of transcription dna templated GO:0006355 213 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
cortical actin cytoskeleton organization GO:0030866 1 0.018
negative regulation of mapk cascade GO:0043409 4 0.018
single organism organelle organization GO:1902589 199 0.018
lipid storage GO:0019915 1 0.018
regulation of response to extracellular stimulus GO:0032104 1 0.018
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of cellular component organization GO:0051128 86 0.018
rna biosynthetic process GO:0032774 181 0.018
generation of neurons GO:0048699 385 0.018
chemosensory behavior GO:0007635 1 0.018
protein localization to plasma membrane GO:0072659 1 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
blood vessel development GO:0001568 246 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.017
regulation of mrna processing GO:0050684 3 0.017
regulation of cell matrix adhesion GO:0001952 1 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
regulation of cell shape GO:0008360 1 0.017
cell matrix adhesion GO:0007160 4 0.017
regulation of cell death GO:0010941 103 0.017
phosphorus metabolic process GO:0006793 109 0.017
programmed cell death GO:0012501 119 0.017
response to external stimulus GO:0009605 264 0.017
aging GO:0007568 2 0.017
positive regulation of cell cycle GO:0045787 3 0.017
proteolysis GO:0006508 38 0.017
embryonic organ morphogenesis GO:0048562 274 0.016
cytokinetic process GO:0032506 2 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
multicellular organism growth GO:0035264 4 0.016
response to uv GO:0009411 3 0.016
nuclear transport GO:0051169 4 0.016
cellular component assembly GO:0022607 170 0.016
regulation of cytoskeleton organization GO:0051493 11 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
regulation of developmental process GO:0050793 247 0.016
protein secretion GO:0009306 1 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
positive regulation of biological process GO:0048518 253 0.016
macromolecular complex subunit organization GO:0043933 74 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
cellular amine metabolic process GO:0044106 2 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
cell substrate adhesion GO:0031589 4 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
taxis GO:0042330 109 0.016
response to drug GO:0042493 3 0.016
long chain fatty acid biosynthetic process GO:0042759 1 0.016
regulation of protein polymerization GO:0032271 2 0.015
positive regulation of secretion GO:0051047 1 0.015
membrane invagination GO:0010324 1 0.015
regulation of biological quality GO:0065008 263 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
regulation of programmed cell death GO:0043067 101 0.015
dna templated transcription elongation GO:0006354 3 0.015
organelle fusion GO:0048284 3 0.015
regulation of biosynthetic process GO:0009889 250 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
establishment of localization GO:0051234 244 0.015
transport GO:0006810 220 0.015
protein polymerization GO:0051258 4 0.015
motor neuron axon guidance GO:0008045 23 0.015
angiogenesis GO:0001525 158 0.015
protein dephosphorylation GO:0006470 3 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
centrosome organization GO:0051297 1 0.015
golgi vesicle transport GO:0048193 3 0.015
amine metabolic process GO:0009308 2 0.015
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.015
regulation of dna templated transcription elongation GO:0032784 3 0.015
positive regulation of molecular function GO:0044093 33 0.015
protein import into nucleus GO:0006606 3 0.015
actin cytoskeleton organization GO:0030036 63 0.015
negative regulation of biological process GO:0048519 304 0.015
cellular response to nutrient levels GO:0031669 2 0.015
chromosome organization involved in meiosis GO:0070192 1 0.014
positive regulation of cellular process GO:0048522 201 0.014
organic acid metabolic process GO:0006082 31 0.014
female meiotic division GO:0007143 2 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.014
meiotic chromosome segregation GO:0045132 3 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
chemotaxis GO:0006935 104 0.014
neuron projection development GO:0031175 180 0.014
protein localization to nucleus GO:0034504 3 0.014
regulation of inflammatory response GO:0050727 2 0.014
membrane fusion GO:0061025 2 0.014
germ line stem cell maintenance GO:0030718 2 0.014
system process GO:0003008 185 0.014
positive regulation of protein polymerization GO:0032273 2 0.014
eye morphogenesis GO:0048592 144 0.014
gland development GO:0048732 143 0.014
regulation of cytokine production GO:0001817 3 0.014
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.014
negative regulation of endopeptidase activity GO:0010951 10 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
rna 3 end processing GO:0031123 2 0.013
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.013
myeloid cell homeostasis GO:0002262 56 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
melanin metabolic process GO:0006582 2 0.013
apoptotic process GO:0006915 116 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
negative regulation of defense response GO:0031348 2 0.013
small molecule metabolic process GO:0044281 77 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
protein complex disassembly GO:0043241 1 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
camera type eye development GO:0043010 222 0.013
alternative mrna splicing via spliceosome GO:0000380 1 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
cellular response to oxygen levels GO:0071453 1 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
stem cell proliferation GO:0072089 4 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of binding GO:0051098 3 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
wnt signaling pathway GO:0016055 80 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
cortical cytoskeleton organization GO:0030865 1 0.012
phagocytosis engulfment GO:0006911 1 0.012
gene expression GO:0010467 252 0.012
digestive system development GO:0055123 289 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
secondary metabolic process GO:0019748 3 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
spermatid development GO:0007286 2 0.012
cellular response to starvation GO:0009267 1 0.012
lipid catabolic process GO:0016042 4 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
protein acetylation GO:0006473 2 0.012
response to chemical GO:0042221 320 0.012
adherens junction organization GO:0034332 4 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
single organism transport GO:0044765 206 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
microtubule organizing center organization GO:0031023 1 0.012
compound eye development GO:0048749 2 0.012
cell substrate junction assembly GO:0007044 2 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
response to glucose GO:0009749 3 0.012
cellular ketone metabolic process GO:0042180 11 0.012
single organism nuclear import GO:1902593 3 0.012
glucose import GO:0046323 2 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
autophagy GO:0006914 4 0.012
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
single organism biosynthetic process GO:0044711 71 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.011
heart morphogenesis GO:0003007 156 0.011
stem cell maintenance GO:0019827 4 0.011
positive regulation of metabolic process GO:0009893 108 0.011
nucleic acid templated transcription GO:0097659 181 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
regulation of apoptotic process GO:0042981 98 0.011
cell proliferation GO:0008283 80 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
cell cycle GO:0007049 93 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
axon guidance GO:0007411 86 0.011
neuron projection guidance GO:0097485 86 0.011
mrna stabilization GO:0048255 4 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
nuclear import GO:0051170 3 0.011
regulation of protein targeting GO:1903533 2 0.011
macromolecule modification GO:0043412 111 0.011
nucleobase containing compound transport GO:0015931 2 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
leukocyte proliferation GO:0070661 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
muscle structure development GO:0061061 196 0.010
positive regulation of immune effector process GO:0002699 3 0.010
chordate embryonic development GO:0043009 271 0.010
macromolecular complex disassembly GO:0032984 1 0.010
fertilization GO:0009566 3 0.010
actin filament polymerization GO:0030041 2 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
regulation of protein metabolic process GO:0051246 56 0.010
female sex differentiation GO:0046660 4 0.010
canonical wnt signaling pathway GO:0060070 48 0.010
spermatid differentiation GO:0048515 2 0.010
establishment of rna localization GO:0051236 3 0.010
regulation of nitrogen compound metabolic process GO:0051171 251 0.010
positive regulation of cell division GO:0051781 2 0.010
mitochondrial transport GO:0006839 2 0.010
positive regulation of cell activation GO:0050867 1 0.010
digestive tract development GO:0048565 265 0.010

gpt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010