Danio rerio

0 known processes

itih2

inter-alpha (globulin) inhibitor H2

(Aliases: wu:fb34d10,wu:fb96f01,id:ibd5015,zgc:56119)

itih2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to organic substance GO:0010033 153 0.264
lipoprotein catabolic process GO:0042159 1 0.260
cellular macromolecule metabolic process GO:0044260 391 0.253
cellular component movement GO:0006928 335 0.247
protein metabolic process GO:0019538 183 0.229
cell motility GO:0048870 244 0.207
homeostatic process GO:0042592 142 0.174
regulation of macromolecule metabolic process GO:0060255 317 0.172
response to nutrient GO:0007584 3 0.154
localization of cell GO:0051674 244 0.151
response to glucose GO:0009749 3 0.150
response to chemical GO:0042221 320 0.130
cellular response to hormone stimulus GO:0032870 39 0.125
response to carbohydrate GO:0009743 3 0.117
single organism transport GO:0044765 206 0.115
regulation of metabolic process GO:0019222 359 0.114
fertilization GO:0009566 3 0.109
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.108
negative regulation of signal transduction GO:0009968 94 0.104
negative regulation of cellular process GO:0048523 283 0.103
anion homeostasis GO:0055081 9 0.103
locomotion GO:0040011 313 0.099
regulation of signaling GO:0023051 235 0.095
lipid homeostasis GO:0055088 3 0.091
cellular response to chemical stimulus GO:0070887 157 0.089
regulation of gene expression GO:0010468 265 0.086
intestinal cholesterol absorption GO:0030299 2 0.084
negative regulation of response to stimulus GO:0048585 104 0.082
cell surface receptor signaling pathway GO:0007166 325 0.081
hemostasis GO:0007599 13 0.081
regulation of wound healing GO:0061041 2 0.079
cellular response to organic substance GO:0071310 105 0.078
regulation of cellular metabolic process GO:0031323 320 0.078
negative regulation of biological process GO:0048519 304 0.078
regulation of biological quality GO:0065008 263 0.076
antimicrobial humoral response GO:0019730 2 0.076
transport GO:0006810 220 0.074
epidermal cell fate specification GO:0009957 4 0.074
single organism localization GO:1902578 225 0.072
organic substance biosynthetic process GO:1901576 289 0.071
phosphate containing compound metabolic process GO:0006796 108 0.071
gene expression GO:0010467 252 0.067
establishment of localization GO:0051234 244 0.066
cellular response to estrogen stimulus GO:0071391 24 0.066
immune system process GO:0002376 241 0.065
system process GO:0003008 185 0.065
regulation of macromolecule biosynthetic process GO:0010556 225 0.063
regulation of cell substrate adhesion GO:0010810 1 0.063
organic cyclic compound biosynthetic process GO:1901362 223 0.063
regulation of biosynthetic process GO:0009889 250 0.063
negative regulation of endopeptidase activity GO:0010951 10 0.061
response to hexose GO:0009746 3 0.061
regulation of cell communication GO:0010646 232 0.060
response to other organism GO:0051707 97 0.060
regulation of inflammatory response GO:0050727 2 0.060
regulation of hemostasis GO:1900046 1 0.059
regulation of primary metabolic process GO:0080090 311 0.059
organic cyclic compound metabolic process GO:1901360 301 0.057
activation of jun kinase activity GO:0007257 2 0.057
cellular response to steroid hormone stimulus GO:0071383 31 0.057
cell migration GO:0016477 237 0.056
response to monosaccharide GO:0034284 3 0.055
response to organic cyclic compound GO:0014070 51 0.054
epithelial cell differentiation GO:0030855 116 0.054
regulation of signal transduction GO:0009966 225 0.053
cellular response to lipid GO:0071396 39 0.053
maintenance of location GO:0051235 4 0.052
response to stress GO:0006950 263 0.052
positive regulation of cellular process GO:0048522 201 0.051
single organism metabolic process GO:0044710 217 0.049
generation of neurons GO:0048699 385 0.048
transcription dna templated GO:0006351 181 0.048
signal transduction GO:0007165 455 0.047
macromolecule biosynthetic process GO:0009059 227 0.047
response to external biotic stimulus GO:0043207 97 0.046
erk1 and erk2 cascade GO:0070371 4 0.046
biosynthetic process GO:0009058 294 0.046
cellular biosynthetic process GO:0044249 286 0.046
regulation of bone remodeling GO:0046850 2 0.045
response to hormone GO:0009725 48 0.045
cerebellar granular layer formation GO:0021684 3 0.044
regulation of response to stress GO:0080134 36 0.044
regulation of response to stimulus GO:0048583 269 0.042
protein activation cascade GO:0072376 6 0.042
defense response to fungus GO:0050832 2 0.041
intestinal absorption GO:0050892 2 0.041
response to external stimulus GO:0009605 264 0.041
cellular response to endogenous stimulus GO:0071495 68 0.041
regulation of sterol transport GO:0032371 3 0.040
blood vessel development GO:0001568 246 0.040
multi organism process GO:0051704 134 0.039
negative regulation of signaling GO:0023057 96 0.038
regulation of cytokine production GO:0001817 3 0.037
toll like receptor signaling pathway GO:0002224 4 0.037
neuron differentiation GO:0030182 353 0.037
brain development GO:0007420 293 0.037
response to steroid hormone GO:0048545 35 0.037
cell substrate adhesion GO:0031589 4 0.037
proteolysis GO:0006508 38 0.037
regulation of catalytic activity GO:0050790 55 0.037
cellular protein metabolic process GO:0044267 129 0.036
cerebellar cortex development GO:0021695 5 0.036
regulation of multicellular organismal process GO:0051239 277 0.036
negative regulation of peptidase activity GO:0010466 10 0.036
phosphorus metabolic process GO:0006793 109 0.036
regulation of hormone secretion GO:0046883 2 0.035
negative regulation of defense response GO:0031348 2 0.035
cell matrix adhesion GO:0007160 4 0.034
positive regulation of biological process GO:0048518 253 0.034
cellular protein catabolic process GO:0044257 4 0.034
vasculature development GO:0001944 278 0.034
aromatic compound biosynthetic process GO:0019438 217 0.033
regulation of blood coagulation GO:0030193 1 0.033
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.033
blood coagulation GO:0007596 12 0.033
female sex differentiation GO:0046660 4 0.033
cell adhesion GO:0007155 40 0.032
response to lipid GO:0033993 60 0.032
phosphorylation GO:0016310 69 0.031
positive regulation of innate immune response GO:0045089 8 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
wound healing GO:0042060 90 0.030
regulation of blood vessel size GO:0050880 2 0.030
rna biosynthetic process GO:0032774 181 0.030
negative regulation of map kinase activity GO:0043407 2 0.030
defense response to other organism GO:0098542 33 0.030
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.029
positive regulation of rna metabolic process GO:0051254 59 0.029
response to estrogen GO:0043627 27 0.029
regulation of jun kinase activity GO:0043506 3 0.028
circulatory system process GO:0003013 87 0.028
cellular response to organic cyclic compound GO:0071407 38 0.028
carbohydrate homeostasis GO:0033500 1 0.028
cellular component disassembly GO:0022411 1 0.028
activation of immune response GO:0002253 9 0.028
regulation of transcription dna templated GO:0006355 213 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
central nervous system development GO:0007417 387 0.028
negative regulation of wound healing GO:0061045 1 0.027
humoral immune response GO:0006959 5 0.027
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.027
regulation of protein metabolic process GO:0051246 56 0.027
cellular lipid catabolic process GO:0044242 3 0.027
intracellular signal transduction GO:0035556 85 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
organic substance transport GO:0071702 58 0.026
negative regulation of sequestering of calcium ion GO:0051283 4 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
rna metabolic process GO:0016070 219 0.026
positive regulation of response to stimulus GO:0048584 80 0.026
convergent extension involved in gastrulation GO:0060027 71 0.025
cytosolic calcium ion transport GO:0060401 3 0.025
negative regulation of protein maturation GO:1903318 10 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
negative regulation of cell communication GO:0010648 96 0.024
sexual reproduction GO:0019953 36 0.024
regulation of response to biotic stimulus GO:0002831 2 0.024
regulation of intracellular signal transduction GO:1902531 57 0.024
negative regulation of protein processing GO:0010955 10 0.024
blood vessel morphogenesis GO:0048514 216 0.024
blood coagulation fibrin clot formation GO:0072378 3 0.023
skeletal system morphogenesis GO:0048705 102 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
chemical homeostasis GO:0048878 49 0.023
positive regulation of metabolic process GO:0009893 108 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
negative regulation of response to external stimulus GO:0032102 9 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
regulation of response to external stimulus GO:0032101 31 0.022
regulation of protein transport GO:0051223 3 0.022
lipid catabolic process GO:0016042 4 0.022
cellular response to molecule of bacterial origin GO:0071219 3 0.022
negative regulation of cytoplasmic transport GO:1903650 2 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
growth GO:0040007 174 0.022
positive regulation of biosynthetic process GO:0009891 68 0.021
aging GO:0007568 2 0.021
nucleic acid metabolic process GO:0090304 244 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
response to endogenous stimulus GO:0009719 83 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
apoptotic process GO:0006915 116 0.021
regulation of endopeptidase activity GO:0052548 23 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
positive regulation of secretion GO:0051047 1 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
response to wounding GO:0009611 116 0.021
autophagy GO:0006914 4 0.021
cell death in response to oxidative stress GO:0036473 2 0.021
positive regulation of blood circulation GO:1903524 2 0.020
heterocycle metabolic process GO:0046483 290 0.020
regulation of localization GO:0032879 104 0.020
iron ion transport GO:0006826 4 0.020
hatching gland development GO:0048785 3 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
regulation of fatty acid metabolic process GO:0019217 1 0.020
regulation of cellular component movement GO:0051270 55 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
lipid metabolic process GO:0006629 52 0.020
cellular amine metabolic process GO:0044106 2 0.020
skeletal system development GO:0001501 181 0.020
carbohydrate biosynthetic process GO:0016051 1 0.019
glucose homeostasis GO:0042593 1 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
b cell activation GO:0042113 2 0.019
meiotic nuclear division GO:0007126 4 0.019
defense response GO:0006952 47 0.019
negative regulation of gene expression GO:0010629 65 0.019
programmed cell death GO:0012501 119 0.019
negative regulation of cell adhesion GO:0007162 6 0.019
regulation of developmental process GO:0050793 247 0.019
cell death GO:0008219 121 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
morphogenesis of an epithelium GO:0002009 333 0.018
positive regulation of transport GO:0051050 2 0.018
cellular lipid metabolic process GO:0044255 36 0.018
death GO:0016265 121 0.018
digestive system development GO:0055123 289 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
positive regulation of exocytosis GO:0045921 1 0.018
glucocorticoid metabolic process GO:0008211 2 0.018
nucleic acid templated transcription GO:0097659 181 0.018
cellular protein modification process GO:0006464 100 0.018
biological adhesion GO:0022610 40 0.018
protein polymerization GO:0051258 4 0.018
sequestering of metal ion GO:0051238 3 0.018
female meiotic division GO:0007143 2 0.018
cerebellar granular layer morphogenesis GO:0021683 3 0.018
sensory organ development GO:0007423 393 0.017
response to vitamin GO:0033273 3 0.017
peptide transport GO:0015833 1 0.017
cell proliferation GO:0008283 80 0.017
cation homeostasis GO:0055080 33 0.017
interspecies interaction between organisms GO:0044419 4 0.017
regulation of defense response GO:0031347 14 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.016
negative regulation of proteolysis GO:0045861 10 0.016
fatty acid oxidation GO:0019395 1 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
myelin assembly GO:0032288 1 0.016
immune response GO:0006955 28 0.016
ear development GO:0043583 127 0.016
lipoprotein metabolic process GO:0042157 4 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
regulation of blood pressure GO:0008217 1 0.016
negative regulation of metabolic process GO:0009892 86 0.016
macromolecule modification GO:0043412 111 0.016
regulation of tissue remodeling GO:0034103 2 0.016
response to biotic stimulus GO:0009607 97 0.015
b cell differentiation GO:0030183 1 0.015
antibacterial humoral response GO:0019731 2 0.015
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.015
inner ear development GO:0048839 126 0.015
endothelial cell migration GO:0043542 19 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.015
neural crest cell differentiation GO:0014033 72 0.015
axon ensheathment in central nervous system GO:0032291 2 0.015
blood circulation GO:0008015 87 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
peptidyl threonine modification GO:0018210 1 0.015
extracellular structure organization GO:0043062 27 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
positive regulation of cell substrate adhesion GO:0010811 1 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
single organism biosynthetic process GO:0044711 71 0.014
neural plate regionalization GO:0060897 10 0.014
tissue remodeling GO:0048771 4 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
central nervous system neuron differentiation GO:0021953 74 0.014
protein modification process GO:0036211 100 0.014
cerebellar granule cell differentiation GO:0021707 3 0.014
pattern recognition receptor signaling pathway GO:0002221 5 0.014
alcohol biosynthetic process GO:0046165 2 0.014
hormone transport GO:0009914 2 0.013
larval development GO:0002164 2 0.013
female gonad development GO:0008585 4 0.013
hormone secretion GO:0046879 2 0.013
stem cell maintenance GO:0019827 4 0.013
fatty acid biosynthetic process GO:0006633 4 0.013
developmental growth GO:0048589 166 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
innate immune response activating signal transduction GO:0002758 5 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
gland development GO:0048732 143 0.013
ameboidal type cell migration GO:0001667 143 0.013
regulation of locomotion GO:0040012 55 0.013
multicellular organismal metabolic process GO:0044236 2 0.013
organelle organization GO:0006996 227 0.013
nitrogen compound metabolic process GO:0006807 319 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
urogenital system development GO:0001655 97 0.013
regulation of multicellular organismal development GO:2000026 223 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
regulation of proteolysis GO:0030162 24 0.012
phagocytosis GO:0006909 3 0.012
macromolecule catabolic process GO:0009057 15 0.012
small molecule metabolic process GO:0044281 77 0.012
positive regulation of jun kinase activity GO:0043507 2 0.012
cell morphogenesis GO:0000902 289 0.012
regulation of tube size GO:0035150 2 0.012
multi organism cellular process GO:0044764 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
fin development GO:0033333 77 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
regeneration GO:0031099 91 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
regulation of cell death GO:0010941 103 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
regulation of cell differentiation GO:0045595 142 0.012
positive regulation of signal transduction GO:0009967 56 0.012
hemoglobin biosynthetic process GO:0042541 8 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
axial mesoderm morphogenesis GO:0048319 8 0.011
regulation of synapse organization GO:0050807 3 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
protein processing GO:0016485 12 0.011
hemopoiesis GO:0030097 183 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
nuclear import GO:0051170 3 0.011
extracellular matrix organization GO:0030198 27 0.011
heart development GO:0007507 313 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
bone remodeling GO:0046849 2 0.011
establishment of localization in cell GO:0051649 77 0.011
response to oxygen containing compound GO:1901700 55 0.011
digestive tract morphogenesis GO:0048546 231 0.011
cellular ketone metabolic process GO:0042180 11 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of rna metabolic process GO:0051252 224 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
neural plate anterior posterior regionalization GO:0021999 8 0.011
regulation of cell motility GO:2000145 46 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
cerebellar granular layer development GO:0021681 3 0.011
protein secretion GO:0009306 1 0.011
adult behavior GO:0030534 2 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
astrocyte differentiation GO:0048708 1 0.011
tube morphogenesis GO:0035239 349 0.010
collagen metabolic process GO:0032963 2 0.010
lipid storage GO:0019915 1 0.010
peripheral nervous system development GO:0007422 55 0.010
regulation of alcohol biosynthetic process GO:1902930 1 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
endosomal transport GO:0016197 2 0.010
lipid oxidation GO:0034440 1 0.010
negative regulation of nuclear division GO:0051784 3 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
cellular component biogenesis GO:0044085 178 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
regulation of cell proliferation GO:0042127 37 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
ectodermal placode development GO:0071696 37 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
mesenchymal cell differentiation GO:0048762 87 0.010
protein catabolic process GO:0030163 7 0.010
positive regulation of immune system process GO:0002684 17 0.010

itih2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.042
disease of anatomical entity DOID:7 0 0.042
hematopoietic system disease DOID:74 0 0.042
disease of metabolism DOID:0014667 0 0.035
inherited metabolic disorder DOID:655 0 0.035
lysosomal storage disease DOID:3211 0 0.011