Danio rerio

147 known processes

tbx5a

T-box 5a

(Aliases: zf-tbx5,tbx5.1,zTbx5,tbx5)

tbx5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 1.000
atrial ventricular junction remodeling GO:0003294 2 0.999
cardiac chamber formation GO:0003207 4 0.999
Mouse
cardiac ventricle formation GO:0003211 1 0.994
Mouse
heart valve formation GO:0003188 4 0.994
glomerulus vasculature development GO:0072012 2 0.990
embryonic heart tube morphogenesis GO:0003143 108 0.989
cell proliferation involved in heart morphogenesis GO:0061323 2 0.989
Zebrafish Mouse
cardiac conduction system development GO:0003161 1 0.981
Mouse
heart valve development GO:0003170 14 0.981
heart field specification GO:0003128 1 0.979
heart looping GO:0001947 94 0.976
embryonic heart tube development GO:0035050 133 0.968
homeostasis of number of cells GO:0048872 62 0.968
Zebrafish
regulation of metabolic process GO:0019222 359 0.961
heart valve morphogenesis GO:0003179 8 0.960
cardiac muscle tissue development GO:0048738 48 0.958
atrioventricular valve formation GO:0003190 3 0.958
heart morphogenesis GO:0003007 156 0.957
muscle cell fate determination GO:0007521 1 0.956
heart jogging GO:0003146 40 0.951
cardiogenic plate morphogenesis GO:0003142 1 0.947
muscle structure development GO:0061061 196 0.945
heart formation GO:0060914 13 0.945
Zebrafish Mouse
intermediate mesoderm development GO:0048389 2 0.940
Zebrafish
gene expression GO:0010467 252 0.939
mesoderm formation GO:0001707 43 0.925
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.921
embryonic organ morphogenesis GO:0048562 274 0.921
cardiac atrium morphogenesis GO:0003209 2 0.919
Mouse
artery morphogenesis GO:0048844 14 0.917
embryonic skeletal system morphogenesis GO:0048704 93 0.916
digestive tract development GO:0048565 265 0.890
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.882
Zebrafish
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.880
myeloid cell homeostasis GO:0002262 56 0.874
Zebrafish
embryonic organ development GO:0048568 381 0.873
cardiac cell fate commitment GO:0060911 1 0.873
endocardium morphogenesis GO:0003160 4 0.862
ameboidal type cell migration GO:0001667 143 0.862
Zebrafish
artery development GO:0060840 22 0.847
atrioventricular valve morphogenesis GO:0003181 6 0.847
proepicardium development GO:0003342 4 0.842
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.842
Zebrafish Mouse
pericardium development GO:0060039 1 0.840
eye development GO:0001654 277 0.833
positive regulation of gastrulation GO:2000543 2 0.831
cell morphogenesis involved in differentiation GO:0000904 195 0.825
Zebrafish
immune system development GO:0002520 191 0.821
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.818
Zebrafish
regulation of heart morphogenesis GO:2000826 17 0.818
Zebrafish Mouse
outflow tract morphogenesis GO:0003151 1 0.814
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.802
Zebrafish
cardiac muscle cell differentiation GO:0055007 30 0.798
bmp signaling pathway involved in heart jogging GO:0003303 14 0.791
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.791
regulation of primary metabolic process GO:0080090 311 0.790
positive regulation of metabolic process GO:0009893 108 0.782
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.781
Zebrafish
camera type eye development GO:0043010 222 0.781
positive regulation of muscle organ development GO:0048636 1 0.781
Mouse
primitive hemopoiesis GO:0060215 27 0.774
embryonic hemopoiesis GO:0035162 53 0.751
Zebrafish
kidney vasculature development GO:0061440 2 0.750
erythrocyte differentiation GO:0030218 54 0.743
Zebrafish
striated muscle cell development GO:0055002 108 0.739
hematopoietic stem cell differentiation GO:0060218 20 0.737
Zebrafish
specification of organ identity GO:0010092 2 0.731
cellular macromolecule biosynthetic process GO:0034645 224 0.715
mesendoderm development GO:0048382 10 0.708
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.706
heterocycle biosynthetic process GO:0018130 215 0.706
morphogenesis of an epithelial fold GO:0060571 1 0.704
Zebrafish
sensory organ development GO:0007423 393 0.696
morphogenesis of an epithelium GO:0002009 333 0.686
tube morphogenesis GO:0035239 349 0.684
regulation of cellular biosynthetic process GO:0031326 245 0.676
pectoral fin development GO:0033339 50 0.673
atrioventricular valve development GO:0003171 11 0.670
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.663
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.652
neuron fate determination GO:0048664 2 0.647
renal system vasculature development GO:0061437 2 0.643
cardiac atrium development GO:0003230 4 0.633
Mouse
endocardium development GO:0003157 9 0.632
organelle organization GO:0006996 227 0.630
embryonic limb morphogenesis GO:0030326 2 0.620
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.615
stem cell differentiation GO:0048863 117 0.613
Human Zebrafish
regulation of rna metabolic process GO:0051252 224 0.610
embryonic skeletal joint development GO:0072498 3 0.604
positive regulation of striated muscle tissue development GO:0045844 1 0.603
Mouse
germ line stem cell division GO:0042078 1 0.590
limb morphogenesis GO:0035108 7 0.586
muscle cell development GO:0055001 115 0.586
endocardium formation GO:0060214 1 0.584
regulation of bone mineralization GO:0030500 2 0.583
regulation of gene expression GO:0010468 265 0.575
glial cell migration GO:0008347 3 0.565
positive regulation of endothelial cell differentiation GO:0045603 2 0.564
cell cycle GO:0007049 93 0.564
nephron tubule epithelial cell differentiation GO:0072160 1 0.559
transcription from rna polymerase ii promoter GO:0006366 80 0.549
Human Zebrafish Mouse
regulation of transcription dna templated GO:0006355 213 0.547
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.544
Zebrafish
auditory receptor cell fate commitment GO:0009912 4 0.535
embryonic neurocranium morphogenesis GO:0048702 15 0.535
cell migration involved in heart development GO:0060973 22 0.533
regulation of cellular metabolic process GO:0031323 320 0.532
nucleobase containing compound metabolic process GO:0006139 274 0.531
homeostatic process GO:0042592 142 0.531
Zebrafish
limb bud formation GO:0060174 2 0.518
regulation of cardiac muscle tissue development GO:0055024 1 0.515
Human Mouse
spinal cord radial glial cell differentiation GO:0021531 2 0.508
hematopoietic progenitor cell differentiation GO:0002244 23 0.502
Zebrafish
embryonic heart tube formation GO:0003144 1 0.502
muscle cell differentiation GO:0042692 139 0.502
cellular nitrogen compound biosynthetic process GO:0044271 218 0.501
regulation of cell differentiation GO:0045595 142 0.496
Human
myeloid cell differentiation GO:0030099 86 0.493
Zebrafish
cellular component morphogenesis GO:0032989 336 0.492
Zebrafish
organelle assembly GO:0070925 110 0.484
distal tubule development GO:0072017 1 0.483
erythrocyte homeostasis GO:0034101 55 0.483
Zebrafish
neural crest cell development GO:0014032 62 0.469
Zebrafish
appendage development GO:0048736 80 0.461
regulation of skeletal muscle fiber development GO:0048742 2 0.455
mesoderm development GO:0007498 88 0.455
Zebrafish
cartilage morphogenesis GO:0060536 13 0.450
Zebrafish
single organism organelle organization GO:1902589 199 0.450
mesoderm morphogenesis GO:0048332 51 0.446
Zebrafish
developmental growth involved in morphogenesis GO:0060560 86 0.442
Zebrafish
organ formation GO:0048645 17 0.441
Zebrafish Mouse
locomotion GO:0040011 313 0.434
Human Zebrafish
embryonic camera type eye formation GO:0060900 10 0.423
eye morphogenesis GO:0048592 144 0.413
larval development GO:0002164 2 0.411
septum transversum development GO:0003343 4 0.407
immune system process GO:0002376 241 0.402
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.399
striated muscle tissue development GO:0014706 110 0.396
regulation of stem cell differentiation GO:2000736 4 0.392
Human
epithalamus development GO:0021538 10 0.382
Zebrafish
atrial cardiac myofibril assembly GO:0055004 2 0.381
photoreceptor cell differentiation GO:0046530 55 0.378
Zebrafish
digestive tract morphogenesis GO:0048546 231 0.375
Zebrafish
inner ear receptor cell fate commitment GO:0060120 4 0.372
hemopoiesis GO:0030097 183 0.370
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.367
nephron epithelium morphogenesis GO:0072088 1 0.366
negative regulation of transcription dna templated GO:0045892 45 0.359
Zebrafish
neuron development GO:0048666 262 0.355
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.353
regulation of multicellular organismal process GO:0051239 277 0.352
Human Zebrafish Mouse
cardiac ventricle morphogenesis GO:0003208 7 0.346
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.345
embryonic cranial skeleton morphogenesis GO:0048701 90 0.344
photoreceptor cell development GO:0042461 40 0.342
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.341
cell motility GO:0048870 244 0.337
Human Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.336
skeletal system morphogenesis GO:0048705 102 0.334
mesodermal cell differentiation GO:0048333 21 0.332
cell fate commitment GO:0045165 99 0.323
Zebrafish
skeletal muscle organ development GO:0060538 78 0.319
negative regulation of multicellular organismal process GO:0051241 69 0.319
Human
convergent extension GO:0060026 118 0.319
Zebrafish
embryonic skeletal joint morphogenesis GO:0060272 3 0.315
olfactory bulb development GO:0021772 4 0.307
nucleobase containing compound biosynthetic process GO:0034654 205 0.306
ventricular cardiac muscle tissue development GO:0003229 3 0.299
Mouse
somatic stem cell maintenance GO:0035019 1 0.297
positive regulation of cell fate specification GO:0042660 1 0.295
striated muscle cell differentiation GO:0051146 129 0.295
neuroblast fate commitment GO:0014017 1 0.291
cardiac ventricle development GO:0003231 9 0.290
Mouse
atrial cardiac muscle cell development GO:0055014 4 0.284
pharyngeal muscle development GO:0043282 4 0.279
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.278
cardiac muscle tissue morphogenesis GO:0055008 7 0.277
aromatic compound biosynthetic process GO:0019438 217 0.277
heart process GO:0003015 71 0.274
Zebrafish
auditory receptor cell fate determination GO:0042668 2 0.274
specification of organ position GO:0010159 3 0.274
Zebrafish
cellular macromolecule metabolic process GO:0044260 391 0.268
regulation of skeletal muscle cell differentiation GO:2001014 1 0.266
epidermis development GO:0008544 48 0.264
sensory organ morphogenesis GO:0090596 200 0.255
positive regulation of muscle tissue development GO:1901863 1 0.255
Mouse
skeletal system development GO:0001501 181 0.254
Zebrafish
endocardial cushion morphogenesis GO:0003203 3 0.248
cellular component biogenesis GO:0044085 178 0.247
embryonic appendage morphogenesis GO:0035113 30 0.245
response to fluid shear stress GO:0034405 2 0.242
spinal cord development GO:0021510 46 0.237
Zebrafish
response to external stimulus GO:0009605 264 0.226
signal transduction GO:0007165 455 0.225
Zebrafish
regulation of cardiac muscle cell differentiation GO:2000725 1 0.224
determination of intestine left right asymmetry GO:0071908 2 0.224
transmembrane transport GO:0055085 120 0.218
embryonic eye morphogenesis GO:0048048 30 0.218
neuromast hair cell development GO:0035675 6 0.217
atrial cardiac muscle cell differentiation GO:0055011 5 0.215
fin development GO:0033333 77 0.211
endothelium development GO:0003158 25 0.210
tissue regeneration GO:0042246 74 0.210
rna metabolic process GO:0016070 219 0.209
retina development in camera type eye GO:0060041 146 0.208
multi organism process GO:0051704 134 0.207
nephron tubule morphogenesis GO:0072078 1 0.206
regulation of sarcomere organization GO:0060297 2 0.203
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.203
transport GO:0006810 220 0.203
mitotic dna integrity checkpoint GO:0044774 4 0.202
regulation of filopodium assembly GO:0051489 2 0.201
mesenchyme development GO:0060485 127 0.199
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.198
muscle cell fate commitment GO:0042693 9 0.191
mesenchymal cell proliferation GO:0010463 1 0.190
positive regulation of mesoderm development GO:2000382 1 0.189
neural crest cell migration GO:0001755 42 0.189
Zebrafish
somitogenesis GO:0001756 87 0.188
Zebrafish
regulation of cell projection organization GO:0031344 44 0.181
nucleic acid metabolic process GO:0090304 244 0.180
negative regulation of muscle organ development GO:0048635 5 0.178
Human
negative regulation of cellular biosynthetic process GO:0031327 55 0.177
Zebrafish
regulation of binding GO:0051098 3 0.176
nephron morphogenesis GO:0072028 2 0.175
determination of heart left right asymmetry GO:0061371 117 0.174
cranial suture morphogenesis GO:0060363 1 0.173
organic cyclic compound biosynthetic process GO:1901362 223 0.171
embryonic digestive tract development GO:0048566 4 0.170
maintenance of location GO:0051235 4 0.169
mesodermal cell fate commitment GO:0001710 14 0.169
regulation of nucleic acid templated transcription GO:1903506 213 0.168
renal system vasculature morphogenesis GO:0061438 1 0.167
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.166
negative regulation of muscle cell differentiation GO:0051148 1 0.164
rna biosynthetic process GO:0032774 181 0.163
endocardial cushion formation GO:0003272 2 0.155
generation of neurons GO:0048699 385 0.155
Zebrafish
biosynthetic process GO:0009058 294 0.154
olfactory lobe development GO:0021988 4 0.154
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.154
Zebrafish
regulation of organ growth GO:0046620 3 0.151
Human Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.149
positive regulation of developmental process GO:0051094 50 0.148
Human Mouse
axis elongation GO:0003401 31 0.147
Zebrafish
aorta development GO:0035904 4 0.145
bone morphogenesis GO:0060349 11 0.145
microglia differentiation GO:0014004 1 0.144
maintenance of blood brain barrier GO:0035633 1 0.143
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.140
craniofacial suture morphogenesis GO:0097094 2 0.138
embryonic skeletal system development GO:0048706 97 0.137
determination of bilateral symmetry GO:0009855 204 0.137
ventricular cardiac muscle cell differentiation GO:0055012 6 0.136
positive regulation of mesodermal cell fate specification GO:0048337 1 0.136
muscle tissue development GO:0060537 110 0.135
negative regulation of nervous system development GO:0051961 22 0.135
optic nerve development GO:0021554 15 0.135
regulation of rna biosynthetic process GO:2001141 213 0.134
embryonic camera type eye morphogenesis GO:0048596 19 0.133
cellular response to antibiotic GO:0071236 1 0.132
morphogenesis of an epithelial sheet GO:0002011 49 0.132
regulation of cell development GO:0060284 100 0.131
gastrulation GO:0007369 208 0.130
Zebrafish
regulation of biological quality GO:0065008 263 0.128
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.128
spinal cord motor neuron differentiation GO:0021522 26 0.127
Zebrafish
specification of symmetry GO:0009799 204 0.126
myofibril assembly GO:0030239 48 0.124
actin cytoskeleton organization GO:0030036 63 0.123
camera type eye morphogenesis GO:0048593 108 0.122
mesenchymal cell differentiation GO:0048762 87 0.120
Zebrafish
negative regulation of chemotaxis GO:0050922 4 0.120
negative regulation of cell fate commitment GO:0010454 13 0.120
regulation of macromolecule biosynthetic process GO:0010556 225 0.118
regulation of nitrogen compound metabolic process GO:0051171 251 0.117
behavior GO:0007610 74 0.114
posterior lateral line system development GO:0048915 46 0.114
positive regulation of biosynthetic process GO:0009891 68 0.114
cardiac cell development GO:0055006 21 0.113
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.112
positive regulation of apoptotic process GO:0043065 29 0.112
embryo development ending in birth or egg hatching GO:0009792 271 0.112
Zebrafish
endodermal cell fate commitment GO:0001711 18 0.111
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.111
Zebrafish
regulation of biomineral tissue development GO:0070167 2 0.109
positive regulation of skeletal muscle tissue development GO:0048643 1 0.109
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.108
Zebrafish
stem cell maintenance GO:0019827 4 0.107
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.106
formation of primary germ layer GO:0001704 62 0.104
Zebrafish
regulation of muscle tissue development GO:1901861 6 0.104
Human Mouse
cardiac muscle cell development GO:0055013 20 0.103
pectoral fin morphogenesis GO:0035138 29 0.103
cellular response to fluid shear stress GO:0071498 1 0.103
regulation of glutamate receptor signaling pathway GO:1900449 1 0.102
negative regulation of axon guidance GO:1902668 1 0.102
somatic motor neuron differentiation GO:0021523 5 0.099
Zebrafish
single organism metabolic process GO:0044710 217 0.098
endothelial cell morphogenesis GO:0001886 1 0.098
stem cell development GO:0048864 82 0.098
Zebrafish
regulation of myotube differentiation GO:0010830 2 0.096
system process GO:0003008 185 0.096
Zebrafish
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.095
protein metabolic process GO:0019538 183 0.094
vasculogenesis GO:0001570 41 0.091
Zebrafish
habenula development GO:0021986 9 0.090
reproductive structure development GO:0048608 5 0.089
negative regulation of rna biosynthetic process GO:1902679 45 0.085
Zebrafish
ear development GO:0043583 127 0.085
Zebrafish
negative regulation of gene expression GO:0010629 65 0.084
Zebrafish
rhombomere morphogenesis GO:0021593 17 0.084
bone mineralization GO:0030282 9 0.083
cellular component assembly GO:0022607 170 0.083
digestive system development GO:0055123 289 0.082
Zebrafish
regulation of endothelial cell differentiation GO:0045601 3 0.081
embryonic pattern specification GO:0009880 44 0.081
kidney vasculature morphogenesis GO:0061439 1 0.079
muscle organ morphogenesis GO:0048644 8 0.079
macromolecule biosynthetic process GO:0009059 227 0.078
gastrulation with mouth forming second GO:0001702 44 0.077
Zebrafish
regulation of developmental process GO:0050793 247 0.077
Human Zebrafish Mouse
positive regulation of cellular process GO:0048522 201 0.077
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.077
Zebrafish
epithelial tube morphogenesis GO:0060562 148 0.077
actomyosin structure organization GO:0031032 53 0.077
anterior posterior pattern specification GO:0009952 152 0.074
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.074
Zebrafish
positive regulation of heart contraction GO:0045823 2 0.073
endodermal cell differentiation GO:0035987 19 0.072
Zebrafish
proximal distal pattern formation GO:0009954 1 0.072
endothelial cell fate commitment GO:0060839 3 0.071
blood vessel endothelial cell differentiation GO:0060837 2 0.070
negative regulation of mesodermal cell fate specification GO:0042662 3 0.070
post anal tail morphogenesis GO:0036342 19 0.069
Zebrafish
cell cell signaling GO:0007267 52 0.069
Human
positive regulation of nucleic acid templated transcription GO:1903508 57 0.069
regeneration GO:0031099 91 0.068
actin filament based process GO:0030029 64 0.068
tissue remodeling GO:0048771 4 0.068
cell differentiation involved in kidney development GO:0061005 13 0.068
female sex differentiation GO:0046660 4 0.067
catechol containing compound biosynthetic process GO:0009713 2 0.067
mesodermal cell fate specification GO:0007501 12 0.066
notochord development GO:0030903 54 0.066
Zebrafish
renal tubule development GO:0061326 5 0.065
kidney epithelium development GO:0072073 23 0.064
Zebrafish
striated muscle cell proliferation GO:0014855 7 0.064
Human Mouse
heart rudiment development GO:0003313 8 0.064
embryonic camera type eye development GO:0031076 29 0.064
connective tissue development GO:0061448 99 0.064
Zebrafish
g1 s transition of mitotic cell cycle GO:0000082 1 0.063
erythrocyte development GO:0048821 24 0.063
retinal cone cell differentiation GO:0042670 12 0.062
Zebrafish
positive regulation of glial cell differentiation GO:0045687 1 0.062
cardiac chamber development GO:0003205 19 0.062
Zebrafish Mouse
regulation of response to stimulus GO:0048583 269 0.061
Zebrafish
axial mesoderm development GO:0048318 10 0.059
Zebrafish
negative regulation of neurogenesis GO:0050768 20 0.059
closure of optic fissure GO:0061386 6 0.059
pharyngeal system development GO:0060037 18 0.058
Zebrafish
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.058
regulation of apoptotic process GO:0042981 98 0.057
apoptotic process involved in development GO:1902742 2 0.057
optic placode formation involved in camera type eye formation GO:0046619 3 0.057
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.057
Zebrafish
regulation of nervous system development GO:0051960 90 0.056
endodermal cell fate specification GO:0001714 17 0.056
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.055
regulation of blood circulation GO:1903522 32 0.055
Zebrafish
endoderm formation GO:0001706 29 0.054
Zebrafish
venous blood vessel morphogenesis GO:0048845 3 0.054
pronephric nephron tubule development GO:0039020 2 0.054
retinal cone cell development GO:0046549 8 0.054
Zebrafish
polarized epithelial cell differentiation GO:0030859 4 0.054
positive regulation of rna biosynthetic process GO:1902680 57 0.054
calcium ion homeostasis GO:0055074 19 0.053
cellular biosynthetic process GO:0044249 286 0.053
blood circulation GO:0008015 87 0.053
Zebrafish
response to external biotic stimulus GO:0043207 97 0.053
regulation of cell fate commitment GO:0010453 22 0.052
neuroepithelial cell differentiation GO:0060563 26 0.052
cellular aldehyde metabolic process GO:0006081 4 0.052
chemical homeostasis GO:0048878 49 0.052
regulation of mitotic cell cycle GO:0007346 25 0.051
cardiac muscle cell fate commitment GO:0060923 1 0.051
anterior posterior axon guidance GO:0033564 5 0.051
nitrogen compound metabolic process GO:0006807 319 0.051
glomerulus morphogenesis GO:0072102 7 0.051
regulation of mesodermal cell fate specification GO:0042661 9 0.051
pathway restricted smad protein phosphorylation GO:0060389 1 0.051
regulation of neurogenesis GO:0050767 87 0.050
tongue morphogenesis GO:0043587 3 0.050
stem cell division GO:0017145 1 0.049
macromolecule localization GO:0033036 54 0.049
endochondral bone morphogenesis GO:0060350 8 0.049
neural crest cell differentiation GO:0014033 72 0.049
Zebrafish
diencephalon development GO:0021536 58 0.049
Zebrafish
pancreatic a cell development GO:0003322 2 0.049
negative regulation of glial cell proliferation GO:0060253 1 0.049
regulation of production of molecular mediator of immune response GO:0002700 1 0.048
meiotic nuclear division GO:0007126 4 0.048
ion homeostasis GO:0050801 41 0.048
nephron development GO:0072006 31 0.048
negative regulation of striated muscle tissue development GO:0045843 2 0.048
Human
response to unfolded protein GO:0006986 2 0.048
regulation of muscle organ development GO:0048634 9 0.048
Human Mouse
negative regulation of biological process GO:0048519 304 0.047
Human Zebrafish
regulation of axon guidance GO:1902667 8 0.047
reproductive process GO:0022414 40 0.047
foregut morphogenesis GO:0007440 4 0.046
rhombomere formation GO:0021594 12 0.046
transcription dna templated GO:0006351 181 0.045
regulation of molecular function GO:0065009 70 0.045
segmentation GO:0035282 97 0.045
Zebrafish
regulation of heart growth GO:0060420 2 0.045
Human Mouse
negative regulation of mitotic cell cycle GO:0045930 11 0.045
cardiocyte differentiation GO:0035051 44 0.045
angioblast cell differentiation GO:0035779 2 0.044
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.044
muscle organ development GO:0007517 101 0.044
Human Zebrafish Mouse
forebrain development GO:0030900 96 0.044
Zebrafish
localization of cell GO:0051674 244 0.043
Human Zebrafish
positive regulation of multicellular organismal process GO:0051240 52 0.043
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.043
monocyte differentiation GO:0030224 2 0.043
photoreceptor cell fate commitment GO:0046552 1 0.042
Zebrafish
negative regulation of nuclear division GO:0051784 3 0.042
determination of digestive tract left right asymmetry GO:0071907 10 0.042
proximal tubule development GO:0072014 3 0.042
regulation of cell fate specification GO:0042659 20 0.041
response to biotic stimulus GO:0009607 97 0.041
positive regulation of biological process GO:0048518 253 0.041
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.041
neuron differentiation GO:0030182 353 0.041
Zebrafish
cell cycle process GO:0022402 53 0.041
pigment cell differentiation GO:0050931 38 0.041
nephron epithelium development GO:0072009 16 0.040
cell migration involved in gastrulation GO:0042074 79 0.040
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.040
Human Zebrafish Mouse
ion transmembrane transport GO:0034220 91 0.040
central nervous system neuron differentiation GO:0021953 74 0.040
Zebrafish
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.040
cardiac muscle cell proliferation GO:0060038 5 0.039
Human Mouse
negative regulation of response to stimulus GO:0048585 104 0.039
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.039
glomerulus vasculature morphogenesis GO:0072103 1 0.039
mechanoreceptor differentiation GO:0042490 37 0.039
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.039
forebrain regionalization GO:0021871 4 0.039
lipid storage GO:0019915 1 0.039
determination of dorsal ventral asymmetry GO:0048262 34 0.038
Zebrafish
negative regulation of mitosis GO:0045839 3 0.038
negative regulation of heart contraction GO:0045822 2 0.038
angiogenesis GO:0001525 158 0.037
Zebrafish
cranial nerve development GO:0021545 42 0.037
endothelial cell differentiation GO:0045446 20 0.037
mitotic cell cycle GO:0000278 64 0.036
developmental induction GO:0031128 10 0.036
regulation of system process GO:0044057 40 0.036
Zebrafish
morphogenesis of embryonic epithelium GO:0016331 30 0.036
regulation of neuron projection development GO:0010975 40 0.035
catecholamine biosynthetic process GO:0042423 2 0.035
regulation of programmed cell death GO:0043067 101 0.035
biomineral tissue development GO:0031214 13 0.035
cellular response to nutrient levels GO:0031669 2 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.035
Zebrafish
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.035
single organism localization GO:1902578 225 0.034
lymphocyte homeostasis GO:0002260 1 0.034
pronephric duct development GO:0039022 13 0.034
Zebrafish
negative regulation of nucleic acid templated transcription GO:1903507 45 0.034
Zebrafish
neural tube patterning GO:0021532 33 0.033
pericardium morphogenesis GO:0003344 1 0.033
brain development GO:0007420 293 0.033
Zebrafish
regulation of organelle assembly GO:1902115 4 0.032
multi organism reproductive process GO:0044703 36 0.032
cell division GO:0051301 20 0.032
mesodermal cell migration GO:0008078 12 0.032
response to wounding GO:0009611 116 0.032
regulation of epidermis development GO:0045682 2 0.032
regulation of tube size GO:0035150 2 0.032
heart rudiment morphogenesis GO:0003314 6 0.031
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.031
regulation of anatomical structure morphogenesis GO:0022603 130 0.031
Zebrafish Mouse
positive regulation of molecular function GO:0044093 33 0.031
reproduction GO:0000003 40 0.031
head morphogenesis GO:0060323 8 0.031
positive regulation of dna templated transcription elongation GO:0032786 1 0.031
canonical wnt signaling pathway GO:0060070 48 0.031
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.030
Zebrafish
optomotor response GO:0071632 1 0.030
negative regulation of macromolecule metabolic process GO:0010605 76 0.030
Zebrafish

tbx5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041