|
|
signal transduction
|
GO:0007165 |
455 |
0.797
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
29 |
0.786
|
|
|
|
response to uv
|
GO:0009411 |
3 |
0.724
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.659
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
29 |
0.648
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.632
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.589
|
Human |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.511
|
Human |
|
|
death
|
GO:0016265 |
121 |
0.483
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.479
|
|
|
|
cell death
|
GO:0008219 |
121 |
0.464
|
|
|
|
response to organic substance
|
GO:0010033 |
153 |
0.459
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.457
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.435
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.397
|
|
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.393
|
|
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.385
|
Human |
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.376
|
|
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.365
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.347
|
Mouse |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.339
|
|
|
|
response to chemical
|
GO:0042221 |
320 |
0.313
|
|
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.299
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.295
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.291
|
Mouse |
|
|
cellular response to light stimulus
|
GO:0071482 |
4 |
0.263
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
28 |
0.258
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.256
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
20 |
0.255
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.251
|
Human |
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.239
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.239
|
|
|
|
response to light stimulus
|
GO:0009416 |
46 |
0.237
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.237
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.236
|
Mouse |
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.235
|
Human |
|
|
cellular response to radiation
|
GO:0071478 |
4 |
0.234
|
|
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.232
|
Mouse |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.228
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.225
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.224
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.222
|
Mouse |
|
|
response to inorganic substance
|
GO:0010035 |
38 |
0.221
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.206
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.205
|
Mouse |
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.200
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.191
|
Mouse |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
7 |
0.190
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.183
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
39 |
0.182
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.180
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
1 |
0.175
|
Mouse |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.173
|
|
|
|
response to methylmercury
|
GO:0051597 |
11 |
0.173
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.171
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.169
|
Mouse |
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.169
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.165
|
|
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.163
|
|
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.162
|
Mouse |
|
|
tissue remodeling
|
GO:0048771 |
4 |
0.161
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
10 |
0.160
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.157
|
Mouse |
|
|
single organism localization
|
GO:1902578 |
225 |
0.156
|
Mouse |
|
|
p38mapk cascade
|
GO:0038066 |
1 |
0.153
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.147
|
Mouse |
|
|
growth
|
GO:0040007 |
174 |
0.145
|
Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.144
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.141
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
10 |
0.140
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.139
|
Human |
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.139
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.129
|
|
|
|
response to metal ion
|
GO:0010038 |
34 |
0.128
|
|
|
|
regulation of system process
|
GO:0044057 |
40 |
0.127
|
|
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.126
|
|
|
|
response to cadmium ion
|
GO:0046686 |
14 |
0.126
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.125
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
2 |
0.125
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.119
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
2 |
0.118
|
Mouse |
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.118
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.118
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
29 |
0.118
|
|
|
|
larval development
|
GO:0002164 |
2 |
0.117
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.113
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
4 |
0.112
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.109
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.109
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
23 |
0.109
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.109
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.107
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.106
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.106
|
|
|
|
aging
|
GO:0007568 |
2 |
0.106
|
|
|
|
camera type eye development
|
GO:0043010 |
222 |
0.104
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.104
|
Mouse |
|
|
response to alkaloid
|
GO:0043279 |
2 |
0.104
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.103
|
|
|
|
female sex differentiation
|
GO:0046660 |
4 |
0.102
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.101
|
|
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.101
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.101
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.101
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.100
|
|
|
|
ovulation cycle
|
GO:0042698 |
2 |
0.098
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.098
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.097
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.096
|
|
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.095
|
Mouse |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.093
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.092
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.091
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.091
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.091
|
|
|
|
response to hormone
|
GO:0009725 |
48 |
0.090
|
|
|
|
urogenital system development
|
GO:0001655 |
97 |
0.089
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.089
|
Mouse |
|
|
cellular component movement
|
GO:0006928 |
335 |
0.089
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.088
|
|
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.087
|
|
|
|
regulation of autophagy
|
GO:0010506 |
3 |
0.087
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.086
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
15 |
0.086
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.086
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.085
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.085
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.084
|
|
|
|
female gonad development
|
GO:0008585 |
4 |
0.083
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.083
|
Mouse |
|
|
zymogen activation
|
GO:0031638 |
3 |
0.082
|
Human |
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.082
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
32 |
0.082
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.080
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.079
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.078
|
|
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.078
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.077
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
48 |
0.077
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.075
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.075
|
|
|
|
transport
|
GO:0006810 |
220 |
0.073
|
Mouse |
|
|
system process
|
GO:0003008 |
185 |
0.073
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.072
|
|
|
|
sleep
|
GO:0030431 |
1 |
0.070
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.070
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.070
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.070
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.068
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
96 |
0.068
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.068
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.068
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.067
|
|
|
|
heart contraction
|
GO:0060047 |
71 |
0.066
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.066
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.065
|
|
|
|
post embryonic morphogenesis
|
GO:0009886 |
4 |
0.065
|
Mouse |
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.065
|
|
|
|
rhythmic process
|
GO:0048511 |
21 |
0.065
|
|
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.064
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.064
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.064
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
3 |
0.064
|
Human |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.063
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.063
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.062
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.062
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
1 |
0.061
|
|
|
|
single organism behavior
|
GO:0044708 |
24 |
0.061
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.061
|
|
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.061
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.061
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
10 |
0.061
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.060
|
|
|
|
kidney development
|
GO:0001822 |
92 |
0.059
|
Mouse |
|
|
ovulation cycle process
|
GO:0022602 |
2 |
0.059
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
1 |
0.059
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
10 |
0.059
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.059
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
1 |
0.059
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.058
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.058
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.057
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.057
|
Human |
|
|
regulation of binding
|
GO:0051098 |
3 |
0.056
|
|
|
|
response to oxidative stress
|
GO:0006979 |
11 |
0.056
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
10 |
0.056
|
|
|
|
lipid metabolic process
|
GO:0006629 |
52 |
0.056
|
|
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
1 |
0.056
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.055
|
Mouse |
|
|
response to virus
|
GO:0009615 |
21 |
0.055
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.055
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.055
|
|
|
|
head development
|
GO:0060322 |
303 |
0.054
|
|
|
|
response to antibiotic
|
GO:0046677 |
1 |
0.054
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.054
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.054
|
|
|
|
somite development
|
GO:0061053 |
96 |
0.054
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
25 |
0.054
|
|
|
|
regulation of p38mapk cascade
|
GO:1900744 |
1 |
0.053
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.052
|
Human |
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.052
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.052
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
2 |
0.051
|
|
|
|
locomotor rhythm
|
GO:0045475 |
3 |
0.051
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
2 |
0.051
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.051
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.051
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.051
|
Human |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.051
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.050
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
2 |
0.050
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
97 |
0.049
|
Mouse |
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.049
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
2 |
0.049
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.049
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.049
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.049
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.048
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.048
|
|
|
|
regulation of molecular function
|
GO:0065009 |
70 |
0.048
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.047
|
Mouse |
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
8 |
0.047
|
|
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.047
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
2 |
0.047
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.047
|
Human Mouse |
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.047
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.047
|
Human |
|
|
cell projection organization
|
GO:0030030 |
284 |
0.046
|
|
|
|
neural retina development
|
GO:0003407 |
49 |
0.046
|
|
|
|
ovarian follicle development
|
GO:0001541 |
2 |
0.046
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.046
|
Mouse |
|
|
hormone transport
|
GO:0009914 |
2 |
0.046
|
|
|
|
thyroid gland development
|
GO:0030878 |
12 |
0.046
|
|
|
|
regulation of protein binding
|
GO:0043393 |
3 |
0.046
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.046
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
1 |
0.046
|
Mouse |
|
|
heart process
|
GO:0003015 |
71 |
0.046
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.046
|
|
|
|
response to steroid hormone
|
GO:0048545 |
35 |
0.046
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
3 |
0.045
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.045
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.045
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.045
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.045
|
|
|
|
cell cycle arrest
|
GO:0007050 |
1 |
0.045
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.044
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.044
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.044
|
|
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.044
|
Human |
|
|
regulation of hormone secretion
|
GO:0046883 |
2 |
0.044
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.043
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
1 |
0.043
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.043
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.042
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.042
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.042
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
116 |
0.041
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
2 |
0.041
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.041
|
|
|
|
ion transport
|
GO:0006811 |
114 |
0.041
|
|
|
|
regulation of skeletal muscle tissue development
|
GO:0048641 |
4 |
0.040
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.040
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
23 |
0.040
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.040
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.040
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.040
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
2 |
0.040
|
Human |
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
1 |
0.040
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.040
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.039
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
33 |
0.039
|
|
|
|
retinal cell programmed cell death
|
GO:0046666 |
2 |
0.039
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.039
|
|
|
|
renal system development
|
GO:0072001 |
94 |
0.039
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.039
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
23 |
0.038
|
|
|
|
response to glucose
|
GO:0009749 |
3 |
0.038
|
|
|
|
response to ketone
|
GO:1901654 |
1 |
0.038
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.037
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.037
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.037
|
|
|
|
endocrine process
|
GO:0050886 |
2 |
0.037
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.037
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.037
|
Mouse |
|
|
catabolic process
|
GO:0009056 |
32 |
0.036
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
38 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
9 |
0.036
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.036
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.036
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.036
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
1 |
0.036
|
|
|
|
hormone secretion
|
GO:0046879 |
2 |
0.036
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.036
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
35 |
0.035
|
Mouse |
|
|
response to monosaccharide
|
GO:0034284 |
3 |
0.035
|
|
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.035
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.035
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.034
|
|
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.034
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.034
|
|
|
|
membrane fusion
|
GO:0061025 |
2 |
0.034
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
24 |
0.034
|
|
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.033
|
Mouse |
|
|
appendage development
|
GO:0048736 |
80 |
0.033
|
Mouse |
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.033
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.033
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.033
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.033
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
2 |
0.033
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.033
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
2 |
0.033
|
|
|
|
macromolecular complex subunit organization
|
GO:0043933 |
74 |
0.033
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
10 |
0.032
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
1 |
0.032
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.032
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
2 |
0.032
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.032
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
1 |
0.032
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
36 |
0.032
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.032
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
2 |
0.032
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
2 |
0.031
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.031
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.031
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.031
|
|
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.031
|
Human |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.030
|
|
|
|
long chain fatty acid metabolic process
|
GO:0001676 |
1 |
0.030
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.030
|
|
|
|
organelle fusion
|
GO:0048284 |
3 |
0.030
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.030
|
Human Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
97 |
0.030
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
2 |
0.030
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.030
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
4 |
0.029
|
|
|
|
steroid hormone secretion
|
GO:0035929 |
1 |
0.029
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
10 |
0.029
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.029
|
Mouse |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.029
|
|
|
|
regulation of locomotion
|
GO:0040012 |
55 |
0.029
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
22 |
0.029
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.029
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
57 |
0.029
|
|
|
|
post embryonic organ morphogenesis
|
GO:0048563 |
1 |
0.029
|
Mouse |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.029
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
3 |
0.029
|
|
|
|
response to vitamin
|
GO:0033273 |
3 |
0.028
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.028
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.028
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.028
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
9 |
0.028
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.028
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
3 |
0.028
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
31 |
0.028
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
2 |
0.028
|
|
|
|
proteolysis
|
GO:0006508 |
38 |
0.028
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.027
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.027
|
Mouse |
|
|
pigmentation
|
GO:0043473 |
85 |
0.027
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.027
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.027
|
|
|
|
macroautophagy
|
GO:0016236 |
1 |
0.027
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.027
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.027
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.027
|
|
|
|
circadian rhythm
|
GO:0007623 |
19 |
0.027
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.027
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
1 |
0.027
|
|
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.027
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.027
|
|
|
|
neuron death
|
GO:0070997 |
21 |
0.026
|
Mouse |
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
2 |
0.026
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.026
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.026
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.026
|
|
|
|
pancreas development
|
GO:0031016 |
84 |
0.026
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.026
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
62 |
0.026
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.025
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.025
|
|
|
|
post embryonic organ development
|
GO:0048569 |
4 |
0.025
|
Mouse |
|
|
regulation of heart contraction
|
GO:0008016 |
32 |
0.025
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.025
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.025
|
|
|
|
regulation of heart growth
|
GO:0060420 |
2 |
0.025
|
|
|
|
activation of immune response
|
GO:0002253 |
9 |
0.025
|
|
|
|
response to oxygen levels
|
GO:0070482 |
25 |
0.024
|
|
|
|
cellular catabolic process
|
GO:0044248 |
27 |
0.024
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.024
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.024
|
|
|
|
retinal cone cell differentiation
|
GO:0042670 |
12 |
0.024
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
1 |
0.024
|
|
|
|
mitochondrion morphogenesis
|
GO:0070584 |
2 |
0.024
|
|
|
|
camera type eye photoreceptor cell differentiation
|
GO:0060219 |
19 |
0.024
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
4 |
0.024
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.024
|
|
|
|
regulation of transport
|
GO:0051049 |
45 |
0.024
|
|
|
|
homeostasis of number of cells within a tissue
|
GO:0048873 |
4 |
0.024
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
1 |
0.024
|
Mouse |
|
|
muscle tissue development
|
GO:0060537 |
110 |
0.023
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
2 |
0.023
|
|
|
|
dna catabolic process
|
GO:0006308 |
1 |
0.023
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.023
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
1 |
0.023
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
2 |
0.023
|
|
|
|
response to unfolded protein
|
GO:0006986 |
2 |
0.023
|
|
|
|
macromolecule localization
|
GO:0033036 |
54 |
0.023
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
1 |
0.023
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.023
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
3 |
0.023
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.023
|
|
|
|
regulation of endocrine process
|
GO:0044060 |
2 |
0.023
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
3 |
0.022
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
3 |
0.022
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.022
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
1 |
0.022
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.022
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.022
|
|
|
|
chemical homeostasis
|
GO:0048878 |
49 |
0.022
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
59 |
0.022
|
|
|
|
diencephalon development
|
GO:0021536 |
58 |
0.022
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.022
|
|
|
|
immune system process
|
GO:0002376 |
241 |
0.022
|
Mouse |
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
79 |
0.022
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.022
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
1 |
0.022
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.022
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
1 |
0.022
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.021
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.021
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.021
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
2 |
0.021
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.021
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
2 |
0.021
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
2 |
0.021
|
|
|
|
multi organism cellular process
|
GO:0044764 |
2 |
0.021
|
Mouse |
|
|
connective tissue development
|
GO:0061448 |
99 |
0.021
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
20 |
0.021
|
|
|
|
secondary metabolic process
|
GO:0019748 |
3 |
0.021
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.021
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.020
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.020
|
Mouse |
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
8 |
0.020
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.020
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
45 |
0.020
|
|
|
|
circulatory system process
|
GO:0003013 |
87 |
0.020
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.020
|
Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
1 |
0.020
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.020
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.020
|
|
|
|
response to lipid
|
GO:0033993 |
60 |
0.020
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
2 |
0.020
|
Mouse |
|
|
rhythmic behavior
|
GO:0007622 |
5 |
0.020
|
|
|
|
sex determination
|
GO:0007530 |
1 |
0.020
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
3 |
0.020
|
|
|
|
endocrine system development
|
GO:0035270 |
65 |
0.020
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
3 |
0.020
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
6 |
0.020
|
|
|
|
blood circulation
|
GO:0008015 |
87 |
0.020
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
35 |
0.020
|
Human |
|
|
response to xenobiotic stimulus
|
GO:0009410 |
45 |
0.019
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
46 |
0.019
|
Human |
|
|
response to nitrogen compound
|
GO:1901698 |
19 |
0.019
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
4 |
0.019
|
|
|
|
compound eye development
|
GO:0048749 |
2 |
0.019
|
|
|
|
cell proliferation
|
GO:0008283 |
80 |
0.019
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
2 |
0.019
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.019
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.019
|
|
|
|
defense response
|
GO:0006952 |
47 |
0.019
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
10 |
0.019
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.019
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
20 |
0.019
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.019
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.019
|
|
|
|
cartilage development
|
GO:0051216 |
96 |
0.019
|
|
|
|
regulation of ion transport
|
GO:0043269 |
22 |
0.018
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.018
|
|
|
|
response to nutrient
|
GO:0007584 |
3 |
0.018
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
4 |
0.018
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
10 |
0.018
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
2 |
0.018
|
|
|
|
autophagy
|
GO:0006914 |
4 |
0.018
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
1 |
0.018
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
56 |
0.018
|
Mouse |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
4 |
0.018
|
|
|
|
response to salt stress
|
GO:0009651 |
10 |
0.018
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.018
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.018
|
|
|
|
protein phosphorylation
|
GO:0006468 |
47 |
0.018
|
|
|
|
b cell activation
|
GO:0042113 |
2 |
0.018
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.018
|
Human Mouse |
