|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
1 |
0.972
|
Fly |
|
|
pronuclear migration
|
GO:0035046 |
1 |
0.922
|
|
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
2 |
0.919
|
|
|
|
oocyte construction
|
GO:0007308 |
5 |
0.782
|
Fly |
|
|
brain development
|
GO:0007420 |
293 |
0.742
|
Human Zebrafish Mouse |
|
|
head development
|
GO:0060322 |
303 |
0.678
|
Human Zebrafish Mouse |
|
|
specification of axis polarity
|
GO:0065001 |
4 |
0.653
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.629
|
Human Zebrafish Mouse |
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.599
|
Human Mouse |
|
|
cognition
|
GO:0050890 |
1 |
0.591
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.566
|
Fly |
|
|
fertilization
|
GO:0009566 |
3 |
0.545
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.539
|
Fly |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.524
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
4 |
0.516
|
|
|
|
single fertilization
|
GO:0007338 |
3 |
0.515
|
|
|
|
oocyte development
|
GO:0048599 |
14 |
0.508
|
Fly |
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.490
|
|
|
|
signal transduction
|
GO:0007165 |
455 |
0.462
|
Fly |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.444
|
Human Mouse Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.393
|
Fly |
|
|
aging
|
GO:0007568 |
2 |
0.392
|
Fly |
|
|
asymmetric protein localization
|
GO:0008105 |
6 |
0.391
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
2 |
0.388
|
Fly |
|
|
midbrain development
|
GO:0030901 |
28 |
0.383
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
4 |
0.381
|
Fly |
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.367
|
Fly |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.360
|
Human Mouse |
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.355
|
Fly |
|
|
larval development
|
GO:0002164 |
2 |
0.346
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.346
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.340
|
|
|
|
protein stabilization
|
GO:0050821 |
2 |
0.330
|
|
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.328
|
|
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.325
|
Fly |
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.324
|
Human Mouse |
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.321
|
Fly |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
29 |
0.318
|
Fly |
|
|
regionalization
|
GO:0003002 |
274 |
0.315
|
Fly |
|
|
axis specification
|
GO:0009798 |
43 |
0.312
|
Fly |
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.305
|
Human Mouse Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
4 |
0.296
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.294
|
Fly |
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.291
|
Fly |
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.291
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
20 |
0.289
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.285
|
Fly |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
3 |
0.281
|
|
|
|
oocyte axis specification
|
GO:0007309 |
5 |
0.281
|
Fly |
|
|
nuclear migration
|
GO:0007097 |
3 |
0.273
|
|
|
|
heart development
|
GO:0007507 |
313 |
0.266
|
Zebrafish |
|
|
response to chemical
|
GO:0042221 |
320 |
0.265
|
Fly |
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.261
|
|
|
|
microtubule based process
|
GO:0007017 |
60 |
0.258
|
Fly |
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.253
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
3 |
0.247
|
|
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.246
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
25 |
0.235
|
Fly |
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.234
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.231
|
Mouse Fly |
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.225
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
4 |
0.220
|
|
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.212
|
Fly |
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.212
|
Fly |
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.211
|
Human Mouse |
|
|
nuclear transport
|
GO:0051169 |
4 |
0.208
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.206
|
Fly |
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.206
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
87 |
0.196
|
|
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.196
|
|
|
|
sexual reproduction
|
GO:0019953 |
36 |
0.195
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
4 |
0.195
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.193
|
|
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.191
|
Fly |
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.189
|
Human Mouse Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.182
|
Fly |
|
|
nucleobase containing compound biosynthetic process
|
GO:0034654 |
205 |
0.181
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
7 |
0.178
|
|
|
|
nucleus localization
|
GO:0051647 |
8 |
0.176
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.171
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.170
|
|
|
|
neurological system process
|
GO:0050877 |
62 |
0.169
|
|
|
|
oocyte differentiation
|
GO:0009994 |
14 |
0.169
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
180 |
0.166
|
Fly |
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
3 |
0.165
|
Fly |
|
|
gamete generation
|
GO:0007276 |
33 |
0.162
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
152 |
0.162
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.161
|
Fly |
|
|
system process
|
GO:0003008 |
185 |
0.151
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
76 |
0.151
|
Human Mouse |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.146
|
Fly |
|
|
multicellular organism reproduction
|
GO:0032504 |
35 |
0.145
|
Fly |
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.141
|
Human Mouse Fly |
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
5 |
0.139
|
Fly |
|
|
gastrulation
|
GO:0007369 |
208 |
0.139
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.137
|
|
|
|
protein localization
|
GO:0008104 |
40 |
0.136
|
Mouse |
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.136
|
Human Mouse |
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.133
|
Fly |
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.131
|
|
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.131
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.129
|
Zebrafish |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.129
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
143 |
0.128
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
15 |
0.128
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
45 |
0.128
|
|
|
|
stem cell maintenance
|
GO:0019827 |
4 |
0.128
|
|
|
|
reproduction
|
GO:0000003 |
40 |
0.127
|
Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
1 |
0.126
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.125
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.124
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
56 |
0.123
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.122
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
36 |
0.122
|
Fly |
|
|
hatching
|
GO:0035188 |
4 |
0.122
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.122
|
Human Mouse |
|
|
organelle localization
|
GO:0051640 |
49 |
0.121
|
|
|
|
localization of cell
|
GO:0051674 |
244 |
0.121
|
Mouse Fly |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.121
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
3 |
0.120
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.119
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.119
|
|
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.118
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
7 |
0.117
|
Fly |
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.115
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.115
|
Human Mouse Fly |
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.115
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
284 |
0.114
|
Fly |
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.114
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
4 |
0.110
|
|
|
|
membrane invagination
|
GO:0010324 |
1 |
0.110
|
Zebrafish |
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
10 |
0.110
|
|
|
|
establishment of localization
|
GO:0051234 |
244 |
0.109
|
Human Zebrafish Mouse |
|
|
cellular component biogenesis
|
GO:0044085 |
178 |
0.109
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
4 |
0.108
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.107
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.102
|
|
|
|
cellular component movement
|
GO:0006928 |
335 |
0.102
|
Mouse Fly |
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.102
|
Fly |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.101
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.099
|
|
|
|
spindle localization
|
GO:0051653 |
12 |
0.098
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
101 |
0.098
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
8 |
0.097
|
Fly |
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.097
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.097
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.096
|
Human Mouse |
|
|
macromolecule localization
|
GO:0033036 |
54 |
0.094
|
Mouse |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.093
|
Fly |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.090
|
|
|
|
cytoskeleton organization
|
GO:0007010 |
96 |
0.090
|
Fly |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.090
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.089
|
|
|
|
cellular localization
|
GO:0051641 |
97 |
0.089
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
2 |
0.088
|
|
|
|
behavior
|
GO:0007610 |
74 |
0.088
|
|
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.087
|
Fly |
|
|
sulfur compound metabolic process
|
GO:0006790 |
13 |
0.087
|
|
|
|
translational initiation
|
GO:0006413 |
3 |
0.087
|
|
|
|
developmental maturation
|
GO:0021700 |
34 |
0.086
|
Fly |
|
|
taxis
|
GO:0042330 |
109 |
0.086
|
Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.085
|
Fly |
|
|
rna localization
|
GO:0006403 |
4 |
0.085
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
2 |
0.085
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
1 |
0.085
|
Fly |
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.084
|
Fly |
|
|
protein polyubiquitination
|
GO:0000209 |
4 |
0.084
|
|
|
|
pole plasm assembly
|
GO:0007315 |
4 |
0.084
|
|
|
|
regulation of localization
|
GO:0032879 |
104 |
0.084
|
Human |
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.083
|
|
|
|
regulation of cell death
|
GO:0010941 |
103 |
0.083
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
3 |
0.081
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.081
|
Fly |
|
|
cell death
|
GO:0008219 |
121 |
0.080
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.079
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.077
|
Fly |
|
|
muscle cell development
|
GO:0055001 |
115 |
0.076
|
|
|
|
female gamete generation
|
GO:0007292 |
14 |
0.076
|
Fly |
|
|
spermatid differentiation
|
GO:0048515 |
2 |
0.075
|
|
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.075
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
25 |
0.074
|
Mouse |
|
|
axon guidance
|
GO:0007411 |
86 |
0.074
|
Fly |
|
|
phosphorylation
|
GO:0016310 |
69 |
0.074
|
Fly |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.073
|
Fly |
|
|
negative regulation of gene expression
|
GO:0010629 |
65 |
0.072
|
|
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.072
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.071
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.071
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.071
|
Mouse Fly |
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.070
|
Human Mouse |
|
|
embryonic pattern specification
|
GO:0009880 |
44 |
0.070
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.070
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
12 |
0.070
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.070
|
Fly |
|
|
establishment of spindle orientation
|
GO:0051294 |
10 |
0.068
|
|
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.067
|
Human |
|
|
germ cell development
|
GO:0007281 |
22 |
0.067
|
Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
18 |
0.067
|
Fly |
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.066
|
Fly |
|
|
cell fate specification
|
GO:0001708 |
68 |
0.065
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
35 |
0.065
|
Fly |
|
|
phagocytosis engulfment
|
GO:0006911 |
1 |
0.065
|
Zebrafish |
|
|
response to temperature stimulus
|
GO:0009266 |
15 |
0.065
|
|
|
|
single organism reproductive process
|
GO:0044702 |
40 |
0.065
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
60 |
0.065
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.065
|
Human Mouse |
|
|
single organism transport
|
GO:0044765 |
206 |
0.064
|
Human Zebrafish Mouse |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.064
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.062
|
|
|
|
compound eye development
|
GO:0048749 |
2 |
0.062
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.061
|
Human Mouse |
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.061
|
|
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.060
|
|
|
|
rna stabilization
|
GO:0043489 |
4 |
0.060
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.060
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.060
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
3 |
0.060
|
|
|
|
reproductive process
|
GO:0022414 |
40 |
0.060
|
Fly |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
58 |
0.059
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.058
|
Human Mouse Fly |
|
|
dna catabolic process
|
GO:0006308 |
1 |
0.058
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.058
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.058
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.058
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
40 |
0.057
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.056
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
77 |
0.055
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.055
|
Fly |
|
|
multi organism process
|
GO:0051704 |
134 |
0.055
|
Fly |
|
|
3 utr mediated mrna stabilization
|
GO:0070935 |
3 |
0.055
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.055
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
16 |
0.054
|
|
|
|
mapk cascade
|
GO:0000165 |
18 |
0.054
|
Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.054
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
3 |
0.054
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
1 |
0.053
|
|
|
|
angiogenesis
|
GO:0001525 |
158 |
0.053
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
1 |
0.052
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
110 |
0.052
|
|
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.051
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
1 |
0.051
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
55 |
0.051
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
3 |
0.051
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.051
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
4 |
0.050
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
52 |
0.050
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.050
|
|
|
|
segmentation
|
GO:0035282 |
97 |
0.050
|
|
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.049
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.049
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
4 |
0.049
|
Human |
|
|
entrainment of circadian clock
|
GO:0009649 |
2 |
0.049
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.049
|
Human Mouse Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
44 |
0.049
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.048
|
Mouse Fly |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
4 |
0.048
|
|
|
|
oogenesis
|
GO:0048477 |
14 |
0.048
|
Fly |
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.048
|
|
|
|
microtubule based movement
|
GO:0007018 |
33 |
0.047
|
|
|
|
nuclear division
|
GO:0000280 |
23 |
0.047
|
Fly |
|
|
regulation of translational initiation
|
GO:0006446 |
1 |
0.047
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
27 |
0.047
|
Fly |
|
|
growth
|
GO:0040007 |
174 |
0.046
|
Fly |
|
|
spermatid development
|
GO:0007286 |
2 |
0.046
|
|
|
|
dephosphorylation
|
GO:0016311 |
11 |
0.046
|
Human Mouse |
|
|
regulation of catalytic activity
|
GO:0050790 |
55 |
0.046
|
|
|
|
single organism cellular localization
|
GO:1902580 |
46 |
0.045
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.045
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.045
|
|
|
|
cell growth
|
GO:0016049 |
57 |
0.045
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.045
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
4 |
0.045
|
|
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.044
|
Fly |
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.044
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.044
|
|
|
|
nuclear export
|
GO:0051168 |
1 |
0.044
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
3 |
0.044
|
|
|
|
homeostatic process
|
GO:0042592 |
142 |
0.044
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
24 |
0.042
|
|
|
|
regulation of mitotic cell cycle embryonic
|
GO:0009794 |
2 |
0.042
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
5 |
0.042
|
Fly |
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.041
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
25 |
0.041
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.041
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
107 |
0.041
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.041
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.041
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.041
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
3 |
0.041
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
16 |
0.041
|
Human Mouse |
|
|
stem cell development
|
GO:0048864 |
82 |
0.041
|
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.040
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.040
|
Fly |
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.039
|
|
|
|
cell maturation
|
GO:0048469 |
23 |
0.039
|
Fly |
|
|
chromosome segregation
|
GO:0007059 |
12 |
0.039
|
|
|
|
mrna stabilization
|
GO:0048255 |
4 |
0.039
|
|
|
|
response to radiation
|
GO:0009314 |
51 |
0.039
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
4 |
0.039
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.038
|
Mouse Fly |
|
|
cellular component assembly
|
GO:0022607 |
170 |
0.038
|
|
|
|
heart process
|
GO:0003015 |
71 |
0.038
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.038
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
4 |
0.038
|
|
|
|
inner ear development
|
GO:0048839 |
126 |
0.038
|
|
|
|
adult behavior
|
GO:0030534 |
2 |
0.037
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
3 |
0.037
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
3 |
0.037
|
Human Mouse |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
1 |
0.037
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
4 |
0.037
|
|
|
|
cell fate determination
|
GO:0001709 |
7 |
0.037
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.037
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.037
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.036
|
|
|
|
death
|
GO:0016265 |
121 |
0.036
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
43 |
0.035
|
Human Mouse Fly |
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.035
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.034
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.034
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
4 |
0.034
|
Fly |
|
|
intracellular transport
|
GO:0046907 |
32 |
0.034
|
Mouse |
|
|
signal transduction in absence of ligand
|
GO:0038034 |
1 |
0.034
|
|
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.033
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
87 |
0.033
|
|
|
|
axon development
|
GO:0061564 |
166 |
0.033
|
Fly |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
93 |
0.033
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.033
|
|
|
|
cell division
|
GO:0051301 |
20 |
0.033
|
Fly |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.033
|
|
|
|
alternative mrna splicing via spliceosome
|
GO:0000380 |
1 |
0.033
|
|
|
|
organic substance transport
|
GO:0071702 |
58 |
0.033
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.032
|
|
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.032
|
Fly |
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.032
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
23 |
0.032
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
24 |
0.031
|
Fly |
|
|
chemotaxis
|
GO:0006935 |
104 |
0.031
|
Fly |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
16 |
0.030
|
|
|
|
response to inorganic substance
|
GO:0010035 |
38 |
0.030
|
|
|
|
protein acetylation
|
GO:0006473 |
2 |
0.030
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
18 |
0.030
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
14 |
0.030
|
|
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.030
|
|
|
|
single organism behavior
|
GO:0044708 |
24 |
0.029
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.029
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
1 |
0.029
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
39 |
0.029
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.029
|
Fly |
|
|
protein acylation
|
GO:0043543 |
3 |
0.029
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
20 |
0.029
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.029
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
25 |
0.029
|
|
|
|
embryonic axis specification
|
GO:0000578 |
12 |
0.029
|
|
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.029
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
3 |
0.029
|
|
|
|
gtp catabolic process
|
GO:0006184 |
2 |
0.028
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.028
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.028
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
50 |
0.028
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
5 |
0.028
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
9 |
0.028
|
|
|
|
membrane organization
|
GO:0061024 |
21 |
0.027
|
Zebrafish |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
3 |
0.027
|
|
|
|
regulation of cell shape
|
GO:0008360 |
1 |
0.027
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.027
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
6 |
0.026
|
Fly |
|
|
regulation of axonogenesis
|
GO:0050770 |
32 |
0.026
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.026
|
|
|
|
digestive system development
|
GO:0055123 |
289 |
0.026
|
|
|
|
regulation of cell motility
|
GO:2000145 |
46 |
0.026
|
|
|
|
regulation of cell migration
|
GO:0030334 |
40 |
0.026
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
3 |
0.026
|
|
|
|
response to drug
|
GO:0042493 |
3 |
0.026
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.026
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
15 |
0.026
|
Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.025
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
2 |
0.025
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.025
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
90 |
0.025
|
|
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.024
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
4 |
0.024
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
1 |
0.024
|
|
|
|
lipid storage
|
GO:0019915 |
1 |
0.024
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
1 |
0.024
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
18 |
0.024
|
Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.024
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.024
|
Human Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
50 |
0.024
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
14 |
0.023
|
Fly |
|
|
neural nucleus development
|
GO:0048857 |
15 |
0.023
|
Human |
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
21 |
0.023
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.023
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.023
|
Fly |
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
3 |
0.023
|
Fly |
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.023
|
|
|
|
cytoplasm organization
|
GO:0007028 |
4 |
0.023
|
|
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.023
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.023
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
4 |
0.022
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.022
|
|
|
|
locomotor rhythm
|
GO:0045475 |
3 |
0.022
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.022
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
2 |
0.022
|
|
|
|
organelle fission
|
GO:0048285 |
23 |
0.022
|
Fly |
|
|
antimicrobial humoral response
|
GO:0019730 |
2 |
0.022
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.022
|
Fly |
|
|
cartilage development
|
GO:0051216 |
96 |
0.022
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
33 |
0.022
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.021
|
|
|
|
forebrain cell migration
|
GO:0021885 |
1 |
0.021
|
|
|
|
meiosis i
|
GO:0007127 |
1 |
0.021
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.021
|
|
|
|
regeneration
|
GO:0031099 |
91 |
0.021
|
|
|
|
oxidation reduction process
|
GO:0055114 |
41 |
0.021
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
5 |
0.021
|
Fly |
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
4 |
0.021
|
Fly |
|
|
response to mechanical stimulus
|
GO:0009612 |
24 |
0.021
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.021
|
|
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
1 |
0.021
|
|
|
|
ear development
|
GO:0043583 |
127 |
0.021
|
|
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.021
|
|
|
|
dna metabolic process
|
GO:0006259 |
27 |
0.021
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.020
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.020
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
42 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
46 |
0.020
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
3 |
0.020
|
|
|
|
protein complex disassembly
|
GO:0043241 |
1 |
0.020
|
|
|
|
transport
|
GO:0006810 |
220 |
0.020
|
Human Zebrafish Mouse |
|
|
meiotic cell cycle
|
GO:0051321 |
5 |
0.020
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.020
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.020
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
3 |
0.020
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.020
|
|
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.020
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.020
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
2 |
0.019
|
Human |
|
|
regulation of cellular component movement
|
GO:0051270 |
55 |
0.019
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
1 |
0.019
|
|
|
|
digestive tract development
|
GO:0048565 |
265 |
0.019
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
4 |
0.019
|
|
|
|
organelle assembly
|
GO:0070925 |
110 |
0.019
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
48 |
0.019
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
22 |
0.019
|
Zebrafish |
|
|
myofibril assembly
|
GO:0030239 |
48 |
0.019
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.019
|
|
|
|
cortical granule exocytosis
|
GO:0060471 |
1 |
0.019
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
20 |
0.019
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.018
|
|
|
|
negative regulation of translation
|
GO:0017148 |
1 |
0.018
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
2 |
0.018
|
|
|
|
cell aging
|
GO:0007569 |
2 |
0.018
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.018
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
5 |
0.018
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.018
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
4 |
0.018
|
|
|
|
startle response
|
GO:0001964 |
4 |
0.018
|
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
2 |
0.018
|
|
|
|
autophagy
|
GO:0006914 |
4 |
0.018
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
2 |
0.018
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
1 |
0.018
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
1 |
0.017
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.017
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
1 |
0.017
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
3 |
0.017
|
|
|
|
response to light stimulus
|
GO:0009416 |
46 |
0.017
|
Fly |
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
2 |
0.017
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.017
|
|
|
|
protein complex subunit organization
|
GO:0071822 |
46 |
0.017
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
2 |
0.017
|
|
|
|
rna splicing
|
GO:0008380 |
16 |
0.017
|
|
|
|
vesicle localization
|
GO:0051648 |
27 |
0.017
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.017
|
|
|
|
cell projection assembly
|
GO:0030031 |
64 |
0.017
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
26 |
0.017
|
Fly |
|
|
neuron migration
|
GO:0001764 |
22 |
0.017
|
Mouse |
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
48 |
0.017
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
80 |
0.017
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
2 |
0.017
|
|
|
|
somitogenesis
|
GO:0001756 |
87 |
0.017
|
|
|
|
blood circulation
|
GO:0008015 |
87 |
0.016
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
53 |
0.016
|
|
|
|
cellular protein localization
|
GO:0034613 |
20 |
0.016
|
Mouse |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
2 |
0.016
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
38 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
11 |
0.016
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.016
|
|
|
|
regulation of alternative mrna splicing via spliceosome
|
GO:0000381 |
1 |
0.016
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
1 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.016
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
3 |
0.016
|
|
|
|
cellular component disassembly
|
GO:0022411 |
1 |
0.016
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
23 |
0.016
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.016
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
63 |
0.016
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
2 |
0.016
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
1 |
0.015
|
|
