Danio rerio

55 known processes

sept6

septin 6

(Aliases: wu:fc54b04,wu:fl76c07,fc54b04,wu:fb70g05,Sep2,zgc:66071)

sept6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 85 0.852
cell projection organization GO:0030030 284 0.749
cell morphogenesis GO:0000902 289 0.530
cellular component assembly GO:0022607 170 0.518
neuron differentiation GO:0030182 353 0.346
regulation of multicellular organismal development GO:2000026 223 0.335
immune system development GO:0002520 191 0.315
convergent extension GO:0060026 118 0.313
neuron development GO:0048666 262 0.244
regulation of developmental process GO:0050793 247 0.211
developmental growth GO:0048589 166 0.195
regulation of protein depolymerization GO:1901879 1 0.173
cellular component biogenesis GO:0044085 178 0.165
regulation of exocytosis GO:0017157 1 0.162
cell substrate adhesion GO:0031589 4 0.157
positive regulation of cell cycle GO:0045787 3 0.157
regulation of multicellular organismal process GO:0051239 277 0.153
synaptic growth at neuromuscular junction GO:0051124 2 0.147
cell matrix adhesion GO:0007160 4 0.145
urogenital system development GO:0001655 97 0.143
regulation of signal transduction GO:0009966 225 0.137
positive regulation of cellular component biogenesis GO:0044089 3 0.136
kidney development GO:0001822 92 0.134
gastrulation GO:0007369 208 0.122
regulation of wnt signaling pathway GO:0030111 53 0.116
wnt signaling pathway GO:0016055 80 0.116
regulation of anatomical structure morphogenesis GO:0022603 130 0.113
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.108
stem cell division GO:0017145 1 0.099
organonitrogen compound biosynthetic process GO:1901566 47 0.097
embryonic organ development GO:0048568 381 0.095
digestive tract morphogenesis GO:0048546 231 0.094
signal transduction GO:0007165 455 0.090
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.089
actin filament polymerization GO:0030041 2 0.089
regulation of cellular component organization GO:0051128 86 0.089
blood vessel morphogenesis GO:0048514 216 0.088
positive regulation of cellular process GO:0048522 201 0.082
positive regulation of glucose import GO:0046326 1 0.079
multi organism process GO:0051704 134 0.077
cognition GO:0050890 1 0.077
cellular component morphogenesis GO:0032989 336 0.076
synaptic vesicle localization GO:0097479 1 0.076
renal system development GO:0072001 94 0.076
immune system process GO:0002376 241 0.073
organelle organization GO:0006996 227 0.070
regulation of establishment of protein localization GO:0070201 4 0.068
cell surface receptor signaling pathway GO:0007166 325 0.067
cellular carbohydrate metabolic process GO:0044262 4 0.066
regulation of cell adhesion GO:0030155 15 0.065
gtp catabolic process GO:0006184 2 0.065
regulation of gtp catabolic process GO:0033124 2 0.064
negative regulation of multicellular organismal process GO:0051241 69 0.064
regulation of protein transport GO:0051223 3 0.063
pronephros development GO:0048793 69 0.063
purine nucleotide metabolic process GO:0006163 27 0.063
development of primary female sexual characteristics GO:0046545 4 0.062
generation of neurons GO:0048699 385 0.061
response to stress GO:0006950 263 0.061
hemopoiesis GO:0030097 183 0.060
localization of cell GO:0051674 244 0.060
positive regulation of biological process GO:0048518 253 0.059
developmental growth involved in morphogenesis GO:0060560 86 0.057
regulation of cell communication GO:0010646 232 0.057
gamete generation GO:0007276 33 0.057
positive regulation of transport GO:0051050 2 0.057
multicellular organism growth GO:0035264 4 0.057
blood vessel development GO:0001568 246 0.056
sensory organ development GO:0007423 393 0.056
regulation of signaling GO:0023051 235 0.055
cellular component movement GO:0006928 335 0.055
actin polymerization or depolymerization GO:0008154 2 0.054
neuronal action potential GO:0019228 18 0.054
inner ear development GO:0048839 126 0.054
nuclear export GO:0051168 1 0.053
heart jogging GO:0003146 40 0.053
pronephros morphogenesis GO:0072114 14 0.053
regulation of erk1 and erk2 cascade GO:0070372 4 0.052
pronephric glomerulus development GO:0039021 13 0.051
positive regulation of exocytosis GO:0045921 1 0.049
nephron tubule morphogenesis GO:0072078 1 0.049
regulation of intracellular protein transport GO:0033157 3 0.048
regulation of binding GO:0051098 3 0.047
positive regulation of oocyte development GO:0060282 1 0.047
cell substrate junction assembly GO:0007044 2 0.047
positive regulation of reproductive process GO:2000243 2 0.045
cell adhesion GO:0007155 40 0.045
glomerular basement membrane development GO:0032836 5 0.044
regulation of protein targeting GO:1903533 2 0.044
g1 s transition of mitotic cell cycle GO:0000082 1 0.043
stem cell maintenance GO:0019827 4 0.043
negative regulation of protein transport GO:0051224 3 0.043
carbohydrate derivative metabolic process GO:1901135 61 0.042
cilium assembly GO:0042384 58 0.042
negative regulation of biological process GO:0048519 304 0.042
cellular nitrogen compound biosynthetic process GO:0044271 218 0.042
regulation of organ morphogenesis GO:2000027 35 0.041
regulation of establishment of planar polarity GO:0090175 4 0.041
glial cell differentiation GO:0010001 42 0.040
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.040
single organism organelle organization GO:1902589 199 0.039
regulation of multicellular organism growth GO:0040014 4 0.039
regulation of protein binding GO:0043393 3 0.039
regulation of synapse assembly GO:0051963 3 0.038
protein polymerization GO:0051258 4 0.038
digestive tract development GO:0048565 265 0.038
nephron epithelium morphogenesis GO:0072088 1 0.037
guanosine containing compound metabolic process GO:1901068 4 0.037
energy reserve metabolic process GO:0006112 2 0.037
mesenchyme development GO:0060485 127 0.037
chordate embryonic development GO:0043009 271 0.037
regulation of heart growth GO:0060420 2 0.036
single organism metabolic process GO:0044710 217 0.036
cell cycle g1 s phase transition GO:0044843 1 0.035
regulation of purine nucleotide catabolic process GO:0033121 2 0.035
renal tubule morphogenesis GO:0061333 1 0.035
regulation of cell matrix adhesion GO:0001952 1 0.034
extracellular structure organization GO:0043062 27 0.034
growth GO:0040007 174 0.033
cell morphogenesis involved in differentiation GO:0000904 195 0.033
intracellular signal transduction GO:0035556 85 0.033
epithelial tube morphogenesis GO:0060562 148 0.033
cell motility GO:0048870 244 0.032
regulation of axonogenesis GO:0050770 32 0.032
response to biotic stimulus GO:0009607 97 0.032
mucopolysaccharide metabolic process GO:1903510 2 0.032
nephron morphogenesis GO:0072028 2 0.032
synaptic vesicle recycling GO:0036465 1 0.031
regulation of nucleotide catabolic process GO:0030811 2 0.031
connective tissue development GO:0061448 99 0.031
positive regulation of gtp catabolic process GO:0033126 1 0.031
regulation of cell substrate adhesion GO:0010810 1 0.031
positive regulation of response to stimulus GO:0048584 80 0.031
protein localization to plasma membrane GO:0072659 1 0.031
locomotion GO:0040011 313 0.030
axis elongation GO:0003401 31 0.030
single organism reproductive process GO:0044702 40 0.030
regulation of localization GO:0032879 104 0.030
calcium ion dependent exocytosis GO:0017156 1 0.030
lymph vessel morphogenesis GO:0036303 25 0.030
mitotic cell cycle GO:0000278 64 0.029
nucleocytoplasmic transport GO:0006913 4 0.029
regulation of cell death GO:0010941 103 0.029
regulation of response to stimulus GO:0048583 269 0.029
cellular protein metabolic process GO:0044267 129 0.029
microtubule based process GO:0007017 60 0.029
regulation of cell shape GO:0008360 1 0.029
protein metabolic process GO:0019538 183 0.029
regulation of protein ubiquitination GO:0031396 3 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
glycosaminoglycan metabolic process GO:0030203 9 0.028
regulation of canonical wnt signaling pathway GO:0060828 34 0.028
cilium organization GO:0044782 71 0.028
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.028
cell projection morphogenesis GO:0048858 244 0.027
nephron development GO:0072006 31 0.026
regulation of organelle assembly GO:1902115 4 0.026
positive regulation of cytoskeleton organization GO:0051495 3 0.026
germ cell migration GO:0008354 8 0.026
dorsal ventral pattern formation GO:0009953 125 0.026
gtp metabolic process GO:0046039 4 0.026
synaptic vesicle endocytosis GO:0048488 1 0.026
neuroblast proliferation GO:0007405 2 0.026
regulation of neuron differentiation GO:0045664 56 0.026
macromolecular complex subunit organization GO:0043933 74 0.026
cellular protein catabolic process GO:0044257 4 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
g protein coupled receptor signaling pathway GO:0007186 74 0.025
regulation of cell size GO:0008361 29 0.025
segmentation GO:0035282 97 0.025
regulation of nervous system development GO:0051960 90 0.025
primary neural tube formation GO:0014020 1 0.025
regulation of synapse organization GO:0050807 3 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.024
regulation of organelle organization GO:0033043 29 0.024
kidney epithelium development GO:0072073 23 0.024
synaptic vesicle transport GO:0048489 1 0.024
erk1 and erk2 cascade GO:0070371 4 0.024
regulation of protein complex disassembly GO:0043244 1 0.024
synapse assembly GO:0007416 9 0.024
myeloid cell differentiation GO:0030099 86 0.024
cytokinesis GO:0000910 3 0.023
negative regulation of cell adhesion GO:0007162 6 0.023
cell part morphogenesis GO:0032990 246 0.023
detection of stimulus GO:0051606 29 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.023
establishment of protein localization to plasma membrane GO:0090002 1 0.023
protein import GO:0017038 3 0.023
exocytosis GO:0006887 1 0.022
system process GO:0003008 185 0.022
epiboly GO:0090504 41 0.022
regulation of gtpase activity GO:0043087 2 0.022
negative regulation of intracellular transport GO:0032387 3 0.022
protein modification by small protein conjugation or removal GO:0070647 14 0.022
convergent extension involved in gastrulation GO:0060027 71 0.021
positive regulation of calcium ion dependent exocytosis GO:0045956 1 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
positive regulation of glucose transport GO:0010828 1 0.021
transmission of nerve impulse GO:0019226 19 0.021
neural crest cell migration GO:0001755 42 0.021
neuron projection morphogenesis GO:0048812 161 0.021
glucose homeostasis GO:0042593 1 0.021
cell adhesion mediated by integrin GO:0033627 1 0.021
female gonad development GO:0008585 4 0.020
somatic muscle development GO:0007525 4 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
epithelial cell morphogenesis GO:0003382 2 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
establishment of vesicle localization GO:0051650 24 0.020
membrane invagination GO:0010324 1 0.020
regulation of rho protein signal transduction GO:0035023 2 0.020
regulation of growth GO:0040008 42 0.020
multi organism reproductive process GO:0044703 36 0.020
negative regulation of ras protein signal transduction GO:0046580 1 0.019
bmp signaling pathway GO:0030509 52 0.019
nephric duct development GO:0072176 13 0.019
protein depolymerization GO:0051261 1 0.019
cellular component disassembly GO:0022411 1 0.019
regulation of cell motility GO:2000145 46 0.019
stem cell proliferation GO:0072089 4 0.019
protein targeting to membrane GO:0006612 1 0.019
epithelial cilium movement GO:0003351 15 0.019
negative regulation of cytoplasmic transport GO:1903650 2 0.019
determination of left right symmetry GO:0007368 179 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of cardiac muscle tissue development GO:0055024 1 0.019
gene expression GO:0010467 252 0.019
protein targeting to nucleus GO:0044744 3 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
striated muscle cell differentiation GO:0051146 129 0.018
tube morphogenesis GO:0035239 349 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
convergent extension involved in axis elongation GO:0060028 26 0.018
negative regulation of intracellular protein transport GO:0090317 3 0.018
cell cycle GO:0007049 93 0.018
protein complex disassembly GO:0043241 1 0.018
cell migration GO:0016477 237 0.017
regulation of autophagy GO:0010506 3 0.017
heparan sulfate proteoglycan metabolic process GO:0030201 6 0.017
extracellular matrix organization GO:0030198 27 0.017
regulation of cell development GO:0060284 100 0.017
ovarian follicle development GO:0001541 2 0.017
stem cell development GO:0048864 82 0.017
neuromuscular junction development GO:0007528 9 0.017
cilium movement GO:0003341 26 0.017
nuclear transport GO:0051169 4 0.017
interaction with host GO:0051701 4 0.017
negative regulation of cellular process GO:0048523 283 0.017
positive regulation of cell adhesion GO:0045785 1 0.016
kidney morphogenesis GO:0060993 15 0.016
actin filament organization GO:0007015 15 0.016
regulation of myeloid cell differentiation GO:0045637 8 0.016
microtubule polymerization or depolymerization GO:0031109 3 0.016
positive regulation of catabolic process GO:0009896 4 0.016
cell death GO:0008219 121 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.016
positive regulation of gene expression GO:0010628 71 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
response to wounding GO:0009611 116 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
positive regulation of muscle tissue development GO:1901863 1 0.016
cellular protein modification process GO:0006464 100 0.016
embryonic epithelial tube formation GO:0001838 17 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
biological adhesion GO:0022610 40 0.016
multicellular organismal response to stress GO:0033555 2 0.016
regulation of cytoplasmic transport GO:1903649 4 0.015
canonical wnt signaling pathway GO:0060070 48 0.015
cortical actin cytoskeleton organization GO:0030866 1 0.015
positive regulation of cell communication GO:0010647 56 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
somatic stem cell maintenance GO:0035019 1 0.015
regulation of immune system process GO:0002682 34 0.015
sulfur compound metabolic process GO:0006790 13 0.015
microtubule based movement GO:0007018 33 0.015
sexual reproduction GO:0019953 36 0.015
cell junction organization GO:0034330 11 0.014
negative regulation of signaling GO:0023057 96 0.014
single fertilization GO:0007338 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
microtubule depolymerization GO:0007019 1 0.014
organelle assembly GO:0070925 110 0.014
aging GO:0007568 2 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
neuron projection development GO:0031175 180 0.014
pronephric nephron development GO:0039019 14 0.014
regulation of purine nucleotide metabolic process GO:1900542 17 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
sensory organ morphogenesis GO:0090596 200 0.014
ovulation cycle process GO:0022602 2 0.014
positive regulation of striated muscle tissue development GO:0045844 1 0.014
phagocytosis engulfment GO:0006911 1 0.013
regulation of oligodendrocyte differentiation GO:0048713 1 0.013
neuron remodeling GO:0016322 1 0.013
blood coagulation GO:0007596 12 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of glucose import GO:0046324 1 0.013
single organism transport GO:0044765 206 0.013
calcium mediated signaling GO:0019722 2 0.013
embryonic skeletal system development GO:0048706 97 0.013
negative regulation of tor signaling GO:0032007 2 0.013
calcium ion import GO:0070509 4 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
macromolecular complex disassembly GO:0032984 1 0.013
negative regulation of cell growth GO:0030308 7 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
reproductive process GO:0022414 40 0.013
detection of external stimulus GO:0009581 24 0.013
regulation of apoptotic process GO:0042981 98 0.013
lymphangiogenesis GO:0001946 25 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
establishment of epithelial cell polarity GO:0090162 2 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
embryonic organ morphogenesis GO:0048562 274 0.012
cardiac cell fate commitment GO:0060911 1 0.012
adrenal gland development GO:0030325 10 0.012
positive regulation of cellular component organization GO:0051130 13 0.012
multicellular organism reproduction GO:0032504 35 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
cellular protein complex disassembly GO:0043624 1 0.012
positive regulation of signal transduction GO:0009967 56 0.012
cell projection assembly GO:0030031 64 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.012
female sex differentiation GO:0046660 4 0.012
synapse organization GO:0050808 21 0.012
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
regulation of calcium mediated signaling GO:0050848 1 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
mitotic cytokinesis GO:0000281 3 0.011
negative regulation of metabolic process GO:0009892 86 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
hard palate development GO:0060022 4 0.011
reflex GO:0060004 2 0.011
maintenance of location GO:0051235 4 0.011
regulation of histone methylation GO:0031060 3 0.011
mitotic cell cycle process GO:1903047 48 0.011
cloaca development GO:0035844 9 0.011
regulation of developmental growth GO:0048638 38 0.011
nucleic acid metabolic process GO:0090304 244 0.011
vasculature development GO:0001944 278 0.011
negative regulation of bmp signaling pathway GO:0030514 13 0.011
regulation of synapse structure and activity GO:0050803 5 0.011
regulation of organ growth GO:0046620 3 0.011
non canonical wnt signaling pathway GO:0035567 13 0.011
spermatid differentiation GO:0048515 2 0.011
lipid storage GO:0019915 1 0.010
chromatin modification GO:0016568 21 0.010
response to organic substance GO:0010033 153 0.010
regulation of cell migration GO:0030334 40 0.010
kupffer s vesicle development GO:0070121 50 0.010
glomerulus development GO:0032835 27 0.010
regulation of calcium ion dependent exocytosis GO:0017158 1 0.010
protein secretion GO:0009306 1 0.010
cellular biosynthetic process GO:0044249 286 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
cyclic nucleotide metabolic process GO:0009187 18 0.010
positive regulation of multi organism process GO:0043902 3 0.010
trabecula morphogenesis GO:0061383 2 0.010

sept6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.158
cancer DOID:162 0 0.035
disease of cellular proliferation DOID:14566 0 0.035
organ system cancer DOID:0050686 0 0.035
nervous system disease DOID:863 0 0.028
retinal disease DOID:5679 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013