Danio rerio

0 known processes

nit2

nitrilase family, member 2

(Aliases: zgc:109720)

nit2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.086
positive regulation of transport GO:0051050 2 0.049
cellular nitrogen compound metabolic process GO:0034641 290 0.045
aging GO:0007568 2 0.042
regulation of multicellular organism growth GO:0040014 4 0.037
maintenance of location GO:0051235 4 0.036
single organism metabolic process GO:0044710 217 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
multicellular organism growth GO:0035264 4 0.033
nucleobase containing compound metabolic process GO:0006139 274 0.032
nitrogen compound metabolic process GO:0006807 319 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.030
cell projection organization GO:0030030 284 0.029
membrane fusion GO:0061025 2 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
regulation of metabolic process GO:0019222 359 0.028
signal transduction GO:0007165 455 0.028
regulation of reproductive process GO:2000241 4 0.028
regulation of protein transport GO:0051223 3 0.027
regulation of establishment of protein localization GO:0070201 4 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
cellular component morphogenesis GO:0032989 336 0.026
cellular biosynthetic process GO:0044249 286 0.025
biosynthetic process GO:0009058 294 0.025
lipid storage GO:0019915 1 0.025
protein localization to nucleus GO:0034504 3 0.025
protein localization to plasma membrane GO:0072659 1 0.025
organic acid metabolic process GO:0006082 31 0.025
nuclear transport GO:0051169 4 0.025
adult behavior GO:0030534 2 0.025
positive regulation of catabolic process GO:0009896 4 0.024
single organism membrane fusion GO:0044801 2 0.024
protein import into nucleus GO:0006606 3 0.024
meiotic cell cycle process GO:1903046 3 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
meiotic nuclear division GO:0007126 4 0.024
gtp catabolic process GO:0006184 2 0.023
positive regulation of cell cycle GO:0045787 3 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
organic substance biosynthetic process GO:1901576 289 0.023
regulation of metal ion transport GO:0010959 4 0.023
gtp metabolic process GO:0046039 4 0.023
stem cell proliferation GO:0072089 4 0.023
autophagy GO:0006914 4 0.023
cellular ketone metabolic process GO:0042180 11 0.022
rna localization GO:0006403 4 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
response to drug GO:0042493 3 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
transport GO:0006810 220 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
system process GO:0003008 185 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
actin polymerization or depolymerization GO:0008154 2 0.022
regulation of cytokine production GO:0001817 3 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
heterocycle biosynthetic process GO:0018130 215 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
neurotransmitter transport GO:0006836 2 0.021
regulation of synapse assembly GO:0051963 3 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
rna biosynthetic process GO:0032774 181 0.021
heterocycle metabolic process GO:0046483 290 0.021
cellular response to nutrient levels GO:0031669 2 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
regulation of protein targeting GO:1903533 2 0.021
single organism nuclear import GO:1902593 3 0.021
small molecule metabolic process GO:0044281 77 0.021
protein complex disassembly GO:0043241 1 0.021
cellular component disassembly GO:0022411 1 0.021
single organism localization GO:1902578 225 0.021
nucleic acid metabolic process GO:0090304 244 0.020
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.020
oxoacid metabolic process GO:0043436 31 0.020
organelle fusion GO:0048284 3 0.020
cellular component movement GO:0006928 335 0.020
rna metabolic process GO:0016070 219 0.020
protein import GO:0017038 3 0.020
gene expression GO:0010467 252 0.020
cellular response to biotic stimulus GO:0071216 3 0.020
cellular protein catabolic process GO:0044257 4 0.020
macromolecular complex disassembly GO:0032984 1 0.020
pole plasm assembly GO:0007315 4 0.020
chemosensory behavior GO:0007635 1 0.019
nuclear import GO:0051170 3 0.019
cell part morphogenesis GO:0032990 246 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
regulation of protein complex assembly GO:0043254 3 0.019
regulation of synapse organization GO:0050807 3 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
cytoplasm organization GO:0007028 4 0.019
synaptic vesicle localization GO:0097479 1 0.019
synaptic vesicle transport GO:0048489 1 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
neuron differentiation GO:0030182 353 0.019
regulation of biosynthetic process GO:0009889 250 0.019
phagocytosis GO:0006909 3 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
morphogenesis of an epithelium GO:0002009 333 0.019
response to chemical GO:0042221 320 0.018
regionalization GO:0003002 274 0.018
endosomal transport GO:0016197 2 0.018
lipid catabolic process GO:0016042 4 0.018
regulation of biological quality GO:0065008 263 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
regulation of sodium ion transport GO:0002028 2 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
protein targeting to nucleus GO:0044744 3 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
cognition GO:0050890 1 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
establishment of localization GO:0051234 244 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
mitochondrion organization GO:0007005 4 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
embryonic organ development GO:0048568 381 0.017
negative regulation of protein localization to nucleus GO:1900181 2 0.017
amine metabolic process GO:0009308 2 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
negative regulation of biological process GO:0048519 304 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
organelle organization GO:0006996 227 0.017
positive regulation of biological process GO:0048518 253 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
regulation of blood pressure GO:0008217 1 0.017
response to hexose GO:0009746 3 0.017
cellular response to starvation GO:0009267 1 0.017
single organism transport GO:0044765 206 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
neuron development GO:0048666 262 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
locomotion GO:0040011 313 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
response to carbohydrate GO:0009743 3 0.017
regulation of primary metabolic process GO:0080090 311 0.017
compound eye development GO:0048749 2 0.017
response to stress GO:0006950 263 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
transcription dna templated GO:0006351 181 0.016
growth GO:0040007 174 0.016
regulation of binding GO:0051098 3 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
cell projection morphogenesis GO:0048858 244 0.016
stem cell maintenance GO:0019827 4 0.016
cytokinesis GO:0000910 3 0.016
spermatid differentiation GO:0048515 2 0.016
cellular amine metabolic process GO:0044106 2 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
tube morphogenesis GO:0035239 349 0.016
single organism organelle organization GO:1902589 199 0.016
exocytosis GO:0006887 1 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
transmembrane transport GO:0055085 120 0.016
regulation of autophagy GO:0010506 3 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
spermatid development GO:0007286 2 0.016
cell morphogenesis GO:0000902 289 0.016
peptide transport GO:0015833 1 0.015
regulation of tube size GO:0035150 2 0.015
regulation of gene expression GO:0010468 265 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
atp catabolic process GO:0006200 4 0.015
nucleic acid templated transcription GO:0097659 181 0.015
regulation of rna metabolic process GO:0051252 224 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
generation of neurons GO:0048699 385 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
sequestering of metal ion GO:0051238 3 0.015
regulation of protein complex disassembly GO:0043244 1 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of gtpase activity GO:0043087 2 0.015
neuroblast proliferation GO:0007405 2 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
developmental growth GO:0048589 166 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
protein polymerization GO:0051258 4 0.015
regulation of blood vessel size GO:0050880 2 0.015
regulation of transporter activity GO:0032409 2 0.015
cellular component assembly GO:0022607 170 0.015
neurotransmitter secretion GO:0007269 2 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
protein metabolic process GO:0019538 183 0.014
small molecule catabolic process GO:0044282 3 0.014
regulation of protein catabolic process GO:0042176 1 0.014
digestive tract morphogenesis GO:0048546 231 0.014
sensory perception of chemical stimulus GO:0007606 3 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
sensory organ development GO:0007423 393 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
digestive tract development GO:0048565 265 0.014
protein acetylation GO:0006473 2 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
response to external stimulus GO:0009605 264 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
intracellular mrna localization GO:0008298 1 0.014
digestive system development GO:0055123 289 0.014
sequestering of calcium ion GO:0051208 3 0.014
cellular lipid catabolic process GO:0044242 3 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
anterior posterior pattern specification GO:0009952 152 0.014
negative regulation of cellular process GO:0048523 283 0.014
carboxylic acid catabolic process GO:0046395 3 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of cell activation GO:0050865 1 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
cellular component biogenesis GO:0044085 178 0.014
regulation of developmental process GO:0050793 247 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
central nervous system development GO:0007417 387 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
neuron neuron synaptic transmission GO:0007270 1 0.013
meiotic chromosome segregation GO:0045132 3 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
regulation of glial cell differentiation GO:0045685 4 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
hormone secretion GO:0046879 2 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
regulation of cell shape GO:0008360 1 0.013
positive regulation of cytokine production GO:0001819 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
heart development GO:0007507 313 0.013
organic acid catabolic process GO:0016054 3 0.013
cell cycle arrest GO:0007050 1 0.013
chordate embryonic development GO:0043009 271 0.013
regulation of signaling GO:0023051 235 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
specification of symmetry GO:0009799 204 0.013
regulation of cell communication GO:0010646 232 0.013
hormone transport GO:0009914 2 0.013
regulation of transcription dna templated GO:0006355 213 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
protein stabilization GO:0050821 2 0.013
homeostatic process GO:0042592 142 0.013
negative regulation of protein transport GO:0051224 3 0.013
regulation of ph GO:0006885 3 0.013
tissue remodeling GO:0048771 4 0.013
actin filament polymerization GO:0030041 2 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
golgi vesicle transport GO:0048193 3 0.012
response to glucose GO:0009749 3 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of signal transduction GO:0009966 225 0.012
regulation of dendrite development GO:0050773 3 0.012
regulation of protein depolymerization GO:1901879 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
cilium morphogenesis GO:0060271 85 0.012
neuron projection development GO:0031175 180 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
cell motility GO:0048870 244 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
positive regulation of blood circulation GO:1903524 2 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
protein secretion GO:0009306 1 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
adherens junction organization GO:0034332 4 0.012
immune system process GO:0002376 241 0.012
circulatory system process GO:0003013 87 0.012
mononuclear cell proliferation GO:0032943 1 0.012
regulation of protein polymerization GO:0032271 2 0.012
female meiotic division GO:0007143 2 0.012
head development GO:0060322 303 0.012
interspecies interaction between organisms GO:0044419 4 0.012
carbohydrate homeostasis GO:0033500 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
leukocyte proliferation GO:0070661 1 0.012
post golgi vesicle mediated transport GO:0006892 1 0.012
blood vessel development GO:0001568 246 0.012
establishment of endothelial barrier GO:0061028 3 0.012
regulation of calcium ion transport GO:0051924 2 0.012
membrane invagination GO:0010324 1 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
regulation of localization GO:0032879 104 0.012
protein depolymerization GO:0051261 1 0.012
b cell activation GO:0042113 2 0.012
action potential GO:0001508 19 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
muscle structure development GO:0061061 196 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
lipid homeostasis GO:0055088 3 0.011
gastrulation GO:0007369 208 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
protein acylation GO:0043543 3 0.011
axon development GO:0061564 166 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
dicarboxylic acid transport GO:0006835 1 0.011
cell migration GO:0016477 237 0.011
vasculature development GO:0001944 278 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
amino acid transport GO:0006865 2 0.011
locomotor rhythm GO:0045475 3 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
protein dephosphorylation GO:0006470 3 0.011
regulation of oocyte development GO:0060281 3 0.011
actin filament based movement GO:0030048 1 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
response to hydrogen peroxide GO:0042542 3 0.011
peptide metabolic process GO:0006518 1 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
localization of cell GO:0051674 244 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
intracellular signal transduction GO:0035556 85 0.011
organelle assembly GO:0070925 110 0.011
regulation of cell differentiation GO:0045595 142 0.011
angiogenesis GO:0001525 158 0.011
negative regulation of catabolic process GO:0009895 3 0.011
fertilization GO:0009566 3 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
response to alkaloid GO:0043279 2 0.011
transmission of nerve impulse GO:0019226 19 0.011
neuronal action potential GO:0019228 18 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
regulation of muscle contraction GO:0006937 3 0.011
regulation of response to stimulus GO:0048583 269 0.011
regulation of membrane potential GO:0042391 23 0.011
brain development GO:0007420 293 0.011
vacuolar transport GO:0007034 2 0.011
phagocytosis engulfment GO:0006911 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
regulation of inflammatory response GO:0050727 2 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
neuron projection morphogenesis GO:0048812 161 0.011
protein homooligomerization GO:0051260 3 0.010
monovalent inorganic cation transport GO:0015672 42 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
glucose homeostasis GO:0042593 1 0.010
single fertilization GO:0007338 3 0.010
cellular protein complex disassembly GO:0043624 1 0.010
immune system development GO:0002520 191 0.010
cell substrate adhesion GO:0031589 4 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
regulation of circadian rhythm GO:0042752 4 0.010
cellular response to oxygen levels GO:0071453 1 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
lymphocyte proliferation GO:0046651 1 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
macroautophagy GO:0016236 1 0.010
eye development GO:0001654 277 0.010
response to nutrient GO:0007584 3 0.010
startle response GO:0001964 4 0.010
phosphorus metabolic process GO:0006793 109 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
multi organism process GO:0051704 134 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
axonogenesis GO:0007409 152 0.010
positive regulation of immune effector process GO:0002699 3 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
blood vessel morphogenesis GO:0048514 216 0.010

nit2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.024
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
musculoskeletal system disease DOID:17 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.011