Danio rerio

0 known processes

zgc:110124

zgc:110124

zgc:110124 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.403
generation of neurons GO:0048699 385 0.229
head development GO:0060322 303 0.220
brain development GO:0007420 293 0.196
central nervous system development GO:0007417 387 0.189
adult behavior GO:0030534 2 0.183
Mouse
biosynthetic process GO:0009058 294 0.182
regulation of multicellular organismal process GO:0051239 277 0.171
Mouse
aging GO:0007568 2 0.169
sensory organ development GO:0007423 393 0.166
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.155
neuron differentiation GO:0030182 353 0.131
signal transduction GO:0007165 455 0.130
Mouse
organic substance biosynthetic process GO:1901576 289 0.126
regulation of gene expression GO:0010468 265 0.119
gene expression GO:0010467 252 0.110
nucleobase containing compound biosynthetic process GO:0034654 205 0.109
cellular biosynthetic process GO:0044249 286 0.109
regulation of cellular metabolic process GO:0031323 320 0.106
Mouse
locomotion GO:0040011 313 0.092
organic cyclic compound biosynthetic process GO:1901362 223 0.091
regulation of biological quality GO:0065008 263 0.091
Mouse
response to amphetamine GO:0001975 1 0.083
eye development GO:0001654 277 0.078
cellular aromatic compound metabolic process GO:0006725 295 0.075
cellular nitrogen compound metabolic process GO:0034641 290 0.073
nitrogen compound metabolic process GO:0006807 319 0.071
neuron projection morphogenesis GO:0048812 161 0.069
dopaminergic neuron differentiation GO:0071542 14 0.067
post embryonic organ development GO:0048569 4 0.067
response to chemical GO:0042221 320 0.066
Mouse
chordate embryonic development GO:0043009 271 0.066
heterocycle metabolic process GO:0046483 290 0.063
phagocytosis GO:0006909 3 0.060
growth GO:0040007 174 0.060
heterocycle biosynthetic process GO:0018130 215 0.059
autophagy GO:0006914 4 0.058
central nervous system neuron differentiation GO:0021953 74 0.056
anterior posterior pattern specification GO:0009952 152 0.056
segmentation GO:0035282 97 0.054
regulation of metabolic process GO:0019222 359 0.054
Mouse
cellular component movement GO:0006928 335 0.052
cell morphogenesis GO:0000902 289 0.051
response to carbohydrate GO:0009743 3 0.051
positive regulation of cell cycle GO:0045787 3 0.049
cellular macromolecule metabolic process GO:0044260 391 0.048
Mouse
establishment of protein localization to organelle GO:0072594 4 0.046
lipid catabolic process GO:0016042 4 0.046
protein metabolic process GO:0019538 183 0.046
Mouse
localization of cell GO:0051674 244 0.045
transcription dna templated GO:0006351 181 0.045
rna biosynthetic process GO:0032774 181 0.045
endothelial cell fate commitment GO:0060839 3 0.045
somite development GO:0061053 96 0.044
regulation of cellular biosynthetic process GO:0031326 245 0.044
digestive tract morphogenesis GO:0048546 231 0.044
diencephalon development GO:0021536 58 0.042
regulation of primary metabolic process GO:0080090 311 0.042
Mouse
cell migration GO:0016477 237 0.042
regulation of biosynthetic process GO:0009889 250 0.042
forebrain development GO:0030900 96 0.042
maintenance of location GO:0051235 4 0.041
guanosine containing compound catabolic process GO:1901069 2 0.041
positive regulation of cellular metabolic process GO:0031325 94 0.041
Mouse
regulation of signaling GO:0023051 235 0.041
Mouse
positive regulation of transport GO:0051050 2 0.041
cognition GO:0050890 1 0.040
neuron development GO:0048666 262 0.040
regulation of nitrogen compound metabolic process GO:0051171 251 0.040
cellular response to external stimulus GO:0071496 2 0.040
Mouse
nucleic acid metabolic process GO:0090304 244 0.040
central nervous system neuron axonogenesis GO:0021955 18 0.039
response to glucose GO:0009749 3 0.039
immune system process GO:0002376 241 0.038
limbic system development GO:0021761 16 0.038
regionalization GO:0003002 274 0.038
stem cell differentiation GO:0048863 117 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
macromolecule biosynthetic process GO:0009059 227 0.038
organic cyclic compound metabolic process GO:1901360 301 0.037
sensory perception of chemical stimulus GO:0007606 3 0.037
regulation of macromolecule metabolic process GO:0060255 317 0.037
Mouse
multicellular organism growth GO:0035264 4 0.036
single organism metabolic process GO:0044710 217 0.036
Mouse
response to monosaccharide GO:0034284 3 0.036
transport GO:0006810 220 0.036
protein targeting to nucleus GO:0044744 3 0.036
spinal cord motor neuron differentiation GO:0021522 26 0.036
intracellular signal transduction GO:0035556 85 0.035
Mouse
nucleocytoplasmic transport GO:0006913 4 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.035
mitochondrion organization GO:0007005 4 0.035
regulation of cell differentiation GO:0045595 142 0.035
negative regulation of biological process GO:0048519 304 0.034
Mouse
sensory organ morphogenesis GO:0090596 200 0.034
regulation of cell activation GO:0050865 1 0.033
regulation of glial cell differentiation GO:0045685 4 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
protein import into nucleus GO:0006606 3 0.033
cellular component morphogenesis GO:0032989 336 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
muscle structure development GO:0061061 196 0.031
positive regulation of camp biosynthetic process GO:0030819 2 0.031
response to hexose GO:0009746 3 0.031
developmental growth GO:0048589 166 0.031
vasculature development GO:0001944 278 0.030
response to amine GO:0014075 1 0.030
gabaergic neuron differentiation GO:0097154 2 0.030
lipid storage GO:0019915 1 0.030
camera type eye development GO:0043010 222 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.029
cellular amine metabolic process GO:0044106 2 0.029
rna metabolic process GO:0016070 219 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
system process GO:0003008 185 0.029
positive regulation of macromolecule metabolic process GO:0010604 93 0.029
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.028
single organism localization GO:1902578 225 0.028
aromatic compound biosynthetic process GO:0019438 217 0.028
photoreceptor cell differentiation GO:0046530 55 0.028
optomotor response GO:0071632 1 0.028
positive regulation of catabolic process GO:0009896 4 0.028
protein modification process GO:0036211 100 0.028
Mouse
cell motility GO:0048870 244 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
negative regulation of cellular process GO:0048523 283 0.027
embryonic organ development GO:0048568 381 0.027
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
regulation of rna metabolic process GO:0051252 224 0.027
regulation of response to stimulus GO:0048583 269 0.027
Mouse
establishment of localization GO:0051234 244 0.027
protein localization to nucleus GO:0034504 3 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
gtp metabolic process GO:0046039 4 0.027
stem cell maintenance GO:0019827 4 0.026
regulation of inflammatory response GO:0050727 2 0.026
amine metabolic process GO:0009308 2 0.026
positive regulation of leukocyte differentiation GO:1902107 1 0.026
neuron projection development GO:0031175 180 0.026
response to organic substance GO:0010033 153 0.026
regulation of protein localization to nucleus GO:1900180 2 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
glucose homeostasis GO:0042593 1 0.025
cell projection organization GO:0030030 284 0.025
regulation of blood vessel size GO:0050880 2 0.025
single organism transport GO:0044765 206 0.025
negative regulation of metabolic process GO:0009892 86 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
regulation of tube size GO:0035150 2 0.024
axonogenesis GO:0007409 152 0.024
neural crest cell development GO:0014032 62 0.024
epithelial tube morphogenesis GO:0060562 148 0.024
cellular protein catabolic process GO:0044257 4 0.024
regulation of cell death GO:0010941 103 0.024
ventral spinal cord development GO:0021517 35 0.024
neurological system process GO:0050877 62 0.024
small molecule metabolic process GO:0044281 77 0.024
apoptotic process GO:0006915 116 0.023
negative regulation of catabolic process GO:0009895 3 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
Mouse
catechol containing compound metabolic process GO:0009712 2 0.023
multi organism process GO:0051704 134 0.023
programmed cell death GO:0012501 119 0.023
nuclear transport GO:0051169 4 0.023
ear morphogenesis GO:0042471 64 0.023
cell differentiation in spinal cord GO:0021515 40 0.022
connective tissue development GO:0061448 99 0.022
death GO:0016265 121 0.022
inner ear development GO:0048839 126 0.022
regulation of signal transduction GO:0009966 225 0.022
Mouse
cell part morphogenesis GO:0032990 246 0.022
cell projection morphogenesis GO:0048858 244 0.022
regulation of gtp catabolic process GO:0033124 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
neuron neuron synaptic transmission GO:0007270 1 0.021
interspecies interaction between organisms GO:0044419 4 0.021
cellular ketone metabolic process GO:0042180 11 0.021
regulation of protein transport GO:0051223 3 0.021
carbohydrate homeostasis GO:0033500 1 0.021
regulation of transcription dna templated GO:0006355 213 0.021
gtp catabolic process GO:0006184 2 0.021
dopamine biosynthetic process GO:0042416 2 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
response to inorganic substance GO:0010035 38 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
regulation of blood pressure GO:0008217 1 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
neural tube development GO:0021915 62 0.020
lymph vessel morphogenesis GO:0036303 25 0.020
negative regulation of gliogenesis GO:0014014 1 0.020
regulation of metal ion transport GO:0010959 4 0.020
protein processing GO:0016485 12 0.020
heart development GO:0007507 313 0.020
organelle organization GO:0006996 227 0.020
cellular localization GO:0051641 97 0.019
multi organism cellular process GO:0044764 2 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
response to abiotic stimulus GO:0009628 122 0.019
response to uv GO:0009411 3 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
developmental maturation GO:0021700 34 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
renal system development GO:0072001 94 0.018
aorta development GO:0035904 4 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
tissue remodeling GO:0048771 4 0.018
Mouse
regulation of reproductive process GO:2000241 4 0.018
heart process GO:0003015 71 0.018
sensory perception of pain GO:0019233 1 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
response to wounding GO:0009611 116 0.018
response to drug GO:0042493 3 0.018
multi organism reproductive process GO:0044703 36 0.018
phagocytosis engulfment GO:0006911 1 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
ear development GO:0043583 127 0.018
protein import GO:0017038 3 0.018
directional locomotion GO:0033058 1 0.018
regulation of protein complex assembly GO:0043254 3 0.018
cell fate commitment GO:0045165 99 0.018
regulation of molecular function GO:0065009 70 0.018
Mouse
regulation of blood circulation GO:1903522 32 0.017
intracellular transport GO:0046907 32 0.017
positive regulation of cell activation GO:0050867 1 0.017
response to alkaloid GO:0043279 2 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
epithelial cell differentiation GO:0030855 116 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
cell death GO:0008219 121 0.017
response to external stimulus GO:0009605 264 0.017
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
retina development in camera type eye GO:0060041 146 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
muscle cell development GO:0055001 115 0.016
regulation of dna replication GO:0006275 3 0.016
nucleic acid templated transcription GO:0097659 181 0.016
stem cell proliferation GO:0072089 4 0.016
gastrulation GO:0007369 208 0.016
golgi vesicle transport GO:0048193 3 0.016
lateral inhibition GO:0046331 1 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
response to light stimulus GO:0009416 46 0.016
central nervous system neuron development GO:0021954 29 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
response to hydrogen peroxide GO:0042542 3 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
skeletal muscle organ development GO:0060538 78 0.016
neuron projection guidance GO:0097485 86 0.016
regulation of cell communication GO:0010646 232 0.016
Mouse
regulation of developmental process GO:0050793 247 0.016
single organism behavior GO:0044708 24 0.016
Mouse
regulation of oligodendrocyte differentiation GO:0048713 1 0.016
neural crest cell differentiation GO:0014033 72 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.015
digestive system development GO:0055123 289 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
cellular component biogenesis GO:0044085 178 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
regulation of cell shape GO:0008360 1 0.015
cellular response to oxygen levels GO:0071453 1 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
regulation of membrane potential GO:0042391 23 0.015
neural tube patterning GO:0021532 33 0.015
establishment of localization in cell GO:0051649 77 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.015
cellular protein modification process GO:0006464 100 0.015
Mouse
midbrain hindbrain boundary development GO:0030917 23 0.015
cell cycle GO:0007049 93 0.015
regulation of localization GO:0032879 104 0.015
oxoacid metabolic process GO:0043436 31 0.014
regulation of protein targeting GO:1903533 2 0.014
cellular response to nutrient levels GO:0031669 2 0.014
Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.014
startle response GO:0001964 4 0.014
regulation of endopeptidase activity GO:0052548 23 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
catechol containing compound biosynthetic process GO:0009713 2 0.014
eye photoreceptor cell differentiation GO:0001754 45 0.014
digestive tract development GO:0048565 265 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
cell growth GO:0016049 57 0.014
regulation of dendrite development GO:0050773 3 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
astrocyte differentiation GO:0048708 1 0.014
sensory perception GO:0007600 39 0.014
negative regulation of cellular biosynthetic process GO:0031327 55 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
regulation of gtpase activity GO:0043087 2 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
cell substrate adhesion GO:0031589 4 0.014
notch signaling pathway GO:0007219 35 0.013
viral process GO:0016032 1 0.013
response to nutrient GO:0007584 3 0.013
positive regulation of cellular process GO:0048522 201 0.013
Mouse
regulation of lyase activity GO:0051339 12 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
mitochondrial transport GO:0006839 2 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
positive regulation of gene expression GO:0010628 71 0.013
peptide transport GO:0015833 1 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
stem cell division GO:0017145 1 0.013
rna localization GO:0006403 4 0.013
cell maturation GO:0048469 23 0.013
regulation of heart contraction GO:0008016 32 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
Mouse
kidney development GO:0001822 92 0.013
protein acylation GO:0043543 3 0.013
morphogenesis of an epithelial sheet GO:0002011 49 0.013
g protein coupled receptor signaling pathway GO:0007186 74 0.013
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.013
cell cell signaling GO:0007267 52 0.013
fertilization GO:0009566 3 0.013
nuclear import GO:0051170 3 0.013
multicellular organismal response to stress GO:0033555 2 0.013
multicellular organism reproduction GO:0032504 35 0.013
organelle fusion GO:0048284 3 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
Mouse
negative regulation of kinase activity GO:0033673 4 0.013
single organism nuclear import GO:1902593 3 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
negative regulation of gene expression GO:0010629 65 0.012
response to oxygen levels GO:0070482 25 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
compound eye development GO:0048749 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
Mouse
response to corticosteroid GO:0031960 1 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
phenol containing compound biosynthetic process GO:0046189 4 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
single organism intracellular transport GO:1902582 25 0.012
positive regulation of metabolic process GO:0009893 108 0.012
Mouse
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
cellular component assembly GO:0022607 170 0.012
regulation of neurogenesis GO:0050767 87 0.012
muscle contraction GO:0006936 18 0.012
response to decreased oxygen levels GO:0036293 25 0.012
regulation of binding GO:0051098 3 0.012
glucocorticoid metabolic process GO:0008211 2 0.012
cellular amino acid biosynthetic process GO:0008652 2 0.012
germ line stem cell maintenance GO:0030718 2 0.012
regulation of cytokine production GO:0001817 3 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
axon extension GO:0048675 45 0.012
lipid metabolic process GO:0006629 52 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
homeostatic process GO:0042592 142 0.012
Mouse
autonomic nervous system development GO:0048483 19 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
semicircular canal development GO:0060872 24 0.011
single organism cellular localization GO:1902580 46 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
epidermis development GO:0008544 48 0.011
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.011
small molecule catabolic process GO:0044282 3 0.011
regulation of locomotion GO:0040012 55 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
post embryonic morphogenesis GO:0009886 4 0.011
gland development GO:0048732 143 0.011
sympathetic nervous system development GO:0048485 3 0.011
meiotic cell cycle process GO:1903046 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
positive regulation of catalytic activity GO:0043085 25 0.011
Mouse
lipid homeostasis GO:0055088 3 0.011
camera type eye morphogenesis GO:0048593 108 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
tube morphogenesis GO:0035239 349 0.011
skeletal system development GO:0001501 181 0.011
macromolecule modification GO:0043412 111 0.011
Mouse
regulation of cellular response to oxidative stress GO:1900407 2 0.011
stem cell fate commitment GO:0048865 1 0.011
zymogen activation GO:0031638 3 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
striated muscle tissue development GO:0014706 110 0.011
ion transport GO:0006811 114 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
response to biotic stimulus GO:0009607 97 0.011
neuroblast differentiation GO:0014016 1 0.011
motor neuron axon guidance GO:0008045 23 0.011
cellular lipid catabolic process GO:0044242 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
visual behavior GO:0007632 10 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
negative regulation of cell motility GO:2000146 17 0.011
protein acetylation GO:0006473 2 0.010
cellular response to light stimulus GO:0071482 4 0.010
cytoskeleton dependent intracellular transport GO:0030705 10 0.010
muscle tissue development GO:0060537 110 0.010
circulatory system process GO:0003013 87 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
developmental programmed cell death GO:0010623 4 0.010
taxis GO:0042330 109 0.010
mesenchymal cell development GO:0014031 78 0.010
cellular response to starvation GO:0009267 1 0.010
Mouse
action potential GO:0001508 19 0.010
muscle organ development GO:0007517 101 0.010
cell matrix adhesion GO:0007160 4 0.010
membrane invagination GO:0010324 1 0.010
negative regulation of transcription dna templated GO:0045892 45 0.010
melanin metabolic process GO:0006582 2 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.010
response to endogenous stimulus GO:0009719 83 0.010
sleep GO:0030431 1 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
negative regulation of reproductive process GO:2000242 3 0.010

zgc:110124 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.013