Danio rerio

0 known processes

tacc3

transforming, acidic coiled-coil containing protein 3

(Aliases: MGC192381,cb500,wu:fd20f10,zgc:111850,sb:cb500)

tacc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasomal protein catabolic process GO:0010498 2 0.512
regulation of chromosome segregation GO:0051983 1 0.394
cellular protein catabolic process GO:0044257 4 0.388
mitotic sister chromatid segregation GO:0000070 6 0.322
embryo development ending in birth or egg hatching GO:0009792 271 0.316
negative regulation of mitosis GO:0045839 3 0.285
negative regulation of nuclear division GO:0051784 3 0.281
cytoskeleton dependent cytokinesis GO:0061640 3 0.256
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.236
modification dependent macromolecule catabolic process GO:0043632 3 0.229
modification dependent protein catabolic process GO:0019941 3 0.224
meiotic cell cycle process GO:1903046 3 0.223
mitotic metaphase plate congression GO:0007080 1 0.199
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.192
regulation of protein catabolic process GO:0042176 1 0.192
spindle assembly involved in mitosis GO:0090307 1 0.182
negative regulation of cellular catabolic process GO:0031330 3 0.176
single organism nuclear import GO:1902593 3 0.175
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.170
organelle fission GO:0048285 23 0.163
mitotic nuclear division GO:0007067 18 0.161
negative regulation of catabolic process GO:0009895 3 0.160
sister chromatid segregation GO:0000819 6 0.153
ubiquitin dependent protein catabolic process GO:0006511 3 0.149
positive regulation of chromosome organization GO:2001252 1 0.147
regulation of proteolysis GO:0030162 24 0.145
negative regulation of cell division GO:0051782 4 0.145
meiosis i GO:0007127 1 0.140
negative regulation of protein phosphorylation GO:0001933 4 0.112
single organism transport GO:0044765 206 0.111
Mouse
single organism organelle organization GO:1902589 199 0.105
Mouse
negative regulation of chromosome organization GO:2001251 1 0.104
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.104
spindle assembly GO:0051225 2 0.104
fertilization GO:0009566 3 0.100
phagocytosis GO:0006909 3 0.096
gene expression GO:0010467 252 0.095
microtubule cytoskeleton organization GO:0000226 33 0.091
Mouse
single organism localization GO:1902578 225 0.090
Mouse
single fertilization GO:0007338 3 0.089
establishment of protein localization to organelle GO:0072594 4 0.089
Mouse
positive regulation of cell cycle GO:0045787 3 0.088
cell cycle GO:0007049 93 0.088
Mouse
apoptotic process GO:0006915 116 0.088
maintenance of location GO:0051235 4 0.086
Mouse
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.085
meiotic nuclear division GO:0007126 4 0.085
protein targeting to nucleus GO:0044744 3 0.084
Mouse
cytokinesis GO:0000910 3 0.082
locomotion GO:0040011 313 0.081
centrosome duplication GO:0051298 1 0.079
regulation of cellular protein catabolic process GO:1903362 1 0.079
protein complex disassembly GO:0043241 1 0.079
negative regulation of protein processing GO:0010955 10 0.078
organelle organization GO:0006996 227 0.077
Mouse
cellular component movement GO:0006928 335 0.075
microtubule organizing center organization GO:0031023 1 0.074
regulation of protein transport GO:0051223 3 0.073
Mouse
negative regulation of proteolysis GO:0045861 10 0.072
cellular component assembly GO:0022607 170 0.069
protein import into nucleus GO:0006606 3 0.067
Mouse
meiosis ii GO:0007135 1 0.065
mitotic cell cycle GO:0000278 64 0.064
organelle localization GO:0051640 49 0.064
Mouse
positive regulation of cell division GO:0051781 2 0.064
nucleobase containing compound metabolic process GO:0006139 274 0.064
single organism metabolic process GO:0044710 217 0.064
regulation of protein processing GO:0070613 10 0.063
nuclear transport GO:0051169 4 0.061
Mouse
larval development GO:0002164 2 0.061
organic cyclic compound metabolic process GO:1901360 301 0.061
positive regulation of catabolic process GO:0009896 4 0.060
regulation of multicellular organism growth GO:0040014 4 0.060
organelle assembly GO:0070925 110 0.060
microtubule depolymerization GO:0007019 1 0.060
multicellular organism growth GO:0035264 4 0.058
centrosome organization GO:0051297 1 0.057
female meiosis chromosome segregation GO:0016321 1 0.057
centrosome cycle GO:0007098 1 0.056
oocyte maturation GO:0001556 4 0.055
male meiosis GO:0007140 2 0.052
transport GO:0006810 220 0.051
Mouse
positive regulation of transport GO:0051050 2 0.051
positive regulation of chromosome segregation GO:0051984 1 0.050
protein localization to nucleus GO:0034504 3 0.050
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.050
generation of neurons GO:0048699 385 0.050
regulation of synapse organization GO:0050807 3 0.049
microtubule polymerization or depolymerization GO:0031109 3 0.048
protein import GO:0017038 3 0.048
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.046
nuclear division GO:0000280 23 0.046
regulation of apoptotic process GO:0042981 98 0.046
regulation of protein ubiquitination GO:0031396 3 0.046
nuclear import GO:0051170 3 0.045
Mouse
regulation of establishment of protein localization GO:0070201 4 0.043
Mouse
chromosome organization GO:0051276 31 0.043
protein ubiquitination GO:0016567 11 0.043
establishment of localization GO:0051234 244 0.042
Mouse
response to stress GO:0006950 263 0.042
Mouse
negative regulation of protein maturation GO:1903318 10 0.041
regulation of protein localization to nucleus GO:1900180 2 0.041
Mouse
nucleocytoplasmic transport GO:0006913 4 0.039
Mouse
aging GO:0007568 2 0.039
regulation of protein targeting GO:1903533 2 0.038
Mouse
meiotic chromosome segregation GO:0045132 3 0.038
female meiotic division GO:0007143 2 0.038
cell cycle process GO:0022402 53 0.038
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.037
negative regulation of macromolecule metabolic process GO:0010605 76 0.037
cell death GO:0008219 121 0.036
macromolecular complex disassembly GO:0032984 1 0.036
regulation of mitotic cell cycle GO:0007346 25 0.036
cleavage furrow formation GO:0036089 2 0.035
cytokinetic process GO:0032506 2 0.035
regulation of meiotic cell cycle GO:0051445 1 0.034
oxoacid metabolic process GO:0043436 31 0.034
regulation of mitotic cell cycle phase transition GO:1901990 8 0.034
stem cell proliferation GO:0072089 4 0.034
regulation of metabolic process GO:0019222 359 0.033
cellular localization GO:0051641 97 0.033
Mouse
cellular protein metabolic process GO:0044267 129 0.033
regulation of cellular metabolic process GO:0031323 320 0.032
programmed cell death GO:0012501 119 0.032
neuron projection development GO:0031175 180 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.031
peptidyl serine phosphorylation GO:0018105 1 0.031
protein polyubiquitination GO:0000209 4 0.031
regulation of biological quality GO:0065008 263 0.031
Mouse
protein metabolic process GO:0019538 183 0.030
regulation of neural precursor cell proliferation GO:2000177 3 0.030
peptidyl threonine modification GO:0018210 1 0.030
regulation of cell death GO:0010941 103 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.029
Mouse
organic substance biosynthetic process GO:1901576 289 0.029
nuclear envelope organization GO:0006998 2 0.028
regulation of protein import into nucleus GO:0042306 2 0.028
Mouse
neuroblast proliferation GO:0007405 2 0.027
heterocycle metabolic process GO:0046483 290 0.027
regulation of dendrite development GO:0050773 3 0.026
heart development GO:0007507 313 0.026
establishment of organelle localization GO:0051656 45 0.026
macromolecule modification GO:0043412 111 0.026
cellular component biogenesis GO:0044085 178 0.025
regulation of synaptic plasticity GO:0048167 1 0.025
mitotic cytokinesis GO:0000281 3 0.025
biosynthetic process GO:0009058 294 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
regulation of protein depolymerization GO:1901879 1 0.025
regulation of primary metabolic process GO:0080090 311 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
positive regulation of biological process GO:0048518 253 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
nuclear migration GO:0007097 3 0.024
chromosome localization GO:0050000 2 0.024
negative regulation of cellular process GO:0048523 283 0.023
Mouse
astral microtubule organization GO:0030953 1 0.023
Mouse
cellular ketone metabolic process GO:0042180 11 0.023
cell migration GO:0016477 237 0.023
negative regulation of metabolic process GO:0009892 86 0.023
neuron differentiation GO:0030182 353 0.023
protein processing GO:0016485 12 0.023
organic acid metabolic process GO:0006082 31 0.023
cellular protein modification process GO:0006464 100 0.022
dna metabolic process GO:0006259 27 0.022
negative regulation of kinase activity GO:0033673 4 0.022
positive regulation of cytoskeleton organization GO:0051495 3 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
mitotic cell cycle process GO:1903047 48 0.022
microtubule bundle formation GO:0001578 9 0.022
regulation of developmental process GO:0050793 247 0.022
cellular amine metabolic process GO:0044106 2 0.022
female meiosis ii GO:0007147 1 0.021
regulation of microtubule depolymerization GO:0031114 1 0.021
small molecule metabolic process GO:0044281 77 0.021
chromosome segregation GO:0007059 12 0.021
regulation of binding GO:0051098 3 0.021
nitric oxide biosynthetic process GO:0006809 2 0.021
response to drug GO:0042493 3 0.021
amine metabolic process GO:0009308 2 0.020
cell substrate adhesion GO:0031589 4 0.020
vesicle transport along microtubule GO:0047496 1 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
regulation of protein binding GO:0043393 3 0.020
protein depolymerization GO:0051261 1 0.020
mitotic cell cycle embryonic GO:0045448 2 0.019
proteolysis GO:0006508 38 0.019
regulation of protein metabolic process GO:0051246 56 0.019
microtubule based process GO:0007017 60 0.019
Mouse
immune system process GO:0002376 241 0.019
Mouse
regulation of protein maturation GO:1903317 10 0.019
negative regulation of biological process GO:0048519 304 0.019
Mouse
regulation of gene expression GO:0010468 265 0.019
regulation of stem cell proliferation GO:0072091 2 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
regulation of neurogenesis GO:0050767 87 0.018
negative regulation of protein transport GO:0051224 3 0.018
Mouse
nucleic acid metabolic process GO:0090304 244 0.018
protein maturation GO:0051604 12 0.018
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.018
negative regulation of intracellular transport GO:0032387 3 0.018
Mouse
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
peptidyl serine modification GO:0018209 2 0.018
multi organism process GO:0051704 134 0.018
angiogenesis GO:0001525 158 0.018
phosphate containing compound metabolic process GO:0006796 108 0.017
negative regulation of protein localization to nucleus GO:1900181 2 0.017
Mouse
regulation of cell communication GO:0010646 232 0.017
blood vessel morphogenesis GO:0048514 216 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
digestive system development GO:0055123 289 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
establishment of localization in cell GO:0051649 77 0.017
Mouse
signal transduction GO:0007165 455 0.017
positive regulation of cellular process GO:0048522 201 0.016
reciprocal dna recombination GO:0035825 1 0.016
negative regulation of neural precursor cell proliferation GO:2000178 1 0.016
protein modification process GO:0036211 100 0.016
cytoskeleton organization GO:0007010 96 0.016
Mouse
negative regulation of cellular protein metabolic process GO:0032269 16 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
cell projection organization GO:0030030 284 0.016
negative regulation of catalytic activity GO:0043086 21 0.016
negative regulation of cellular component organization GO:0051129 16 0.016
regulation of programmed cell death GO:0043067 101 0.016
peptidyl threonine phosphorylation GO:0018107 1 0.016
mitotic g2 m transition checkpoint GO:0044818 3 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
Mouse
protein homooligomerization GO:0051260 3 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
chromosome organization involved in meiosis GO:0070192 1 0.015
cellular component disassembly GO:0022411 1 0.015
regulation of cellular component organization GO:0051128 86 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
neuron development GO:0048666 262 0.015
vasculature development GO:0001944 278 0.015
developmental growth GO:0048589 166 0.015
death GO:0016265 121 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cell cycle g2 m phase transition GO:0044839 4 0.015
meiotic spindle organization GO:0000212 1 0.014
cellular protein complex disassembly GO:0043624 1 0.014
regulation of nervous system development GO:0051960 90 0.014
leukocyte proliferation GO:0070661 1 0.014
blood vessel development GO:0001568 246 0.014
establishment of spindle localization GO:0051293 12 0.014
immune system development GO:0002520 191 0.014
Mouse
regulation of mitosis GO:0007088 9 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
negative regulation of cell cycle process GO:0010948 9 0.014
rna metabolic process GO:0016070 219 0.014
cellular amino acid metabolic process GO:0006520 7 0.013
regulation of microtubule polymerization or depolymerization GO:0031110 3 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
regulation of molecular function GO:0065009 70 0.013
single organism reproductive process GO:0044702 40 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
germ line stem cell maintenance GO:0030718 2 0.013
histone phosphorylation GO:0016572 2 0.013
regulation of catalytic activity GO:0050790 55 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
Mouse
homeostatic process GO:0042592 142 0.012
negative regulation of developmental process GO:0051093 65 0.012
phosphorus metabolic process GO:0006793 109 0.012
organelle fusion GO:0048284 3 0.012
cellular catabolic process GO:0044248 27 0.012
regulation of signaling GO:0023051 235 0.012
adult behavior GO:0030534 2 0.012
negative regulation of cell death GO:0060548 60 0.012
regulation of cell development GO:0060284 100 0.012
cell motility GO:0048870 244 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
regulation of heart growth GO:0060420 2 0.012
phosphorylation GO:0016310 69 0.011
behavior GO:0007610 74 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
protein polymerization GO:0051258 4 0.011
macromolecular complex assembly GO:0065003 35 0.011
homologous chromosome segregation GO:0045143 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
protein localization GO:0008104 40 0.011
Mouse
negative regulation of cell communication GO:0010648 96 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
regulation of cell cycle GO:0051726 52 0.011
Mouse
catabolic process GO:0009056 32 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
Mouse
response to antibiotic GO:0046677 1 0.011
post embryonic organ development GO:0048569 4 0.011
microtubule polymerization GO:0046785 2 0.010
negative regulation of cell cycle phase transition GO:1901988 5 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
striated muscle cell development GO:0055002 108 0.010
organophosphate biosynthetic process GO:0090407 23 0.010
pronuclear migration GO:0035046 1 0.010
regulation of dna replication GO:0006275 3 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
Mouse
somatic muscle development GO:0007525 4 0.010

tacc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.012
organ system cancer DOID:0050686 0 0.010