Danio rerio

17 known processes

pkz

protein kinase containing Z-DNA binding domains

(Aliases: MGC136657,zgc:136657,MGC158143)

pkz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism cellular process GO:0044764 2 0.474
Human Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.255
Human Mouse
response to other organism GO:0051707 97 0.234
Human
interspecies interaction between organisms GO:0044419 4 0.208
Human Mouse
response to biotic stimulus GO:0009607 97 0.198
Human
response to virus GO:0009615 21 0.192
Human
immune system process GO:0002376 241 0.169
Mouse
negative regulation of cellular process GO:0048523 283 0.165
Human Mouse
regulation of metabolic process GO:0019222 359 0.165
Human Mouse
response to external biotic stimulus GO:0043207 97 0.159
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.139
Human Mouse
regulation of gene expression GO:0010468 265 0.133
Human
nuclear transport GO:0051169 4 0.132
negative regulation of biological process GO:0048519 304 0.132
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.131
Human
positive regulation of biological process GO:0048518 253 0.130
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.125
Mouse
response to external stimulus GO:0009605 264 0.122
Human
female sex differentiation GO:0046660 4 0.114
viral process GO:0016032 1 0.107
Human Mouse
multi organism process GO:0051704 134 0.104
Human Mouse
sensory organ development GO:0007423 393 0.103
cellular aromatic compound metabolic process GO:0006725 295 0.099
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.098
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.091
Mouse
rna biosynthetic process GO:0032774 181 0.088
Human
regulation of stem cell proliferation GO:0072091 2 0.085
Mouse
regulation of transcription dna templated GO:0006355 213 0.084
Human
positive regulation of cytokine production GO:0001819 2 0.081
Mouse
heterocycle biosynthetic process GO:0018130 215 0.080
Human
regulation of nucleocytoplasmic transport GO:0046822 2 0.079
stem cell proliferation GO:0072089 4 0.075
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.075
regulation of signaling GO:0023051 235 0.073
Human Mouse
heterocycle metabolic process GO:0046483 290 0.070
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.069
Human
gene expression GO:0010467 252 0.069
Human Mouse
regulation of cytoplasmic transport GO:1903649 4 0.069
signal transduction GO:0007165 455 0.068
Human Mouse
response to organic substance GO:0010033 153 0.068
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.067
Human
negative regulation of gene expression GO:0010629 65 0.066
Human
regulation of glucose import GO:0046324 1 0.061
regulation of rna biosynthetic process GO:2001141 213 0.061
Human
nik nf kappab signaling GO:0038061 1 0.061
Mouse
regulation of reproductive process GO:2000241 4 0.060
cell projection organization GO:0030030 284 0.060
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.060
Mouse
regulation of cell communication GO:0010646 232 0.059
Human Mouse
response to stress GO:0006950 263 0.058
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.057
zymogen activation GO:0031638 3 0.056
interaction with host GO:0051701 4 0.056
cellular macromolecule biosynthetic process GO:0034645 224 0.055
Human Mouse
immune system development GO:0002520 191 0.054
Mouse
regulation of signal transduction GO:0009966 225 0.054
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.054
Human
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.054
nucleobase containing compound biosynthetic process GO:0034654 205 0.053
Human
regulation of nitrogen compound metabolic process GO:0051171 251 0.053
Human
response to chemical GO:0042221 320 0.052
Human Mouse
regulation of rna metabolic process GO:0051252 224 0.051
Human
establishment of localization GO:0051234 244 0.050
determination of bilateral symmetry GO:0009855 204 0.050
i kappab kinase nf kappab signaling GO:0007249 4 0.049
defense response GO:0006952 47 0.048
regulation of cellular metabolic process GO:0031323 320 0.047
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.047
Human Mouse
chordate embryonic development GO:0043009 271 0.047
regulation of cellular biosynthetic process GO:0031326 245 0.045
Human
regulation of immune system process GO:0002682 34 0.045
Mouse
regulation of circadian rhythm GO:0042752 4 0.045
cellular localization GO:0051641 97 0.045
regulation of response to stimulus GO:0048583 269 0.044
Human Mouse
development of primary female sexual characteristics GO:0046545 4 0.043
positive regulation of transport GO:0051050 2 0.043
female gonad development GO:0008585 4 0.043
regulation of biological quality GO:0065008 263 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.042
organic substance biosynthetic process GO:1901576 289 0.042
Human Mouse
cellular response to stress GO:0033554 62 0.042
Mouse
regulation of cytokine production GO:0001817 3 0.042
Mouse
nucleic acid templated transcription GO:0097659 181 0.041
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.041
defense response to other organism GO:0098542 33 0.041
cell morphogenesis GO:0000902 289 0.041
biosynthetic process GO:0009058 294 0.041
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.040
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
Human
transcription dna templated GO:0006351 181 0.039
Human
regulation of stem cell differentiation GO:2000736 4 0.039
Mouse
protein metabolic process GO:0019538 183 0.038
embryonic organ development GO:0048568 381 0.038
response to organic cyclic compound GO:0014070 51 0.037
protein localization to nucleus GO:0034504 3 0.037
hormone secretion GO:0046879 2 0.036
organic cyclic compound biosynthetic process GO:1901362 223 0.036
Human
regulation of protein complex assembly GO:0043254 3 0.036
Mouse
response to exogenous dsrna GO:0043330 6 0.036
cellular response to topologically incorrect protein GO:0035967 2 0.035
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.035
Human
morphogenesis of an epithelium GO:0002009 333 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
Human
glucose import GO:0046323 2 0.033
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.033
positive regulation of response to stimulus GO:0048584 80 0.033
Human Mouse
rna metabolic process GO:0016070 219 0.033
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.032
innate immune response GO:0045087 13 0.032
neuron development GO:0048666 262 0.031
cellular component movement GO:0006928 335 0.031
larval development GO:0002164 2 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
response to dsrna GO:0043331 7 0.031
cellular component morphogenesis GO:0032989 336 0.031
head development GO:0060322 303 0.030
er nucleus signaling pathway GO:0006984 2 0.030
Mouse
aging GO:0007568 2 0.030
meiotic nuclear division GO:0007126 4 0.030
inner ear development GO:0048839 126 0.030
response to glucocorticoid GO:0051384 1 0.030
protein import GO:0017038 3 0.030
positive regulation of catabolic process GO:0009896 4 0.029
regulation of primary metabolic process GO:0080090 311 0.029
Human
negative regulation of protein localization to nucleus GO:1900181 2 0.029
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.029
neuromast development GO:0048884 46 0.029
positive regulation of cell killing GO:0031343 2 0.028
positive regulation of gene expression GO:0010628 71 0.028
blood vessel morphogenesis GO:0048514 216 0.028
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.028
regulation of glucose transport GO:0010827 1 0.028
cellular response to dsrna GO:0071359 1 0.028
response to corticosteroid GO:0031960 1 0.028
cellular component assembly GO:0022607 170 0.028
Mouse
androgen metabolic process GO:0008209 2 0.028
energy reserve metabolic process GO:0006112 2 0.027
positive regulation of cell adhesion GO:0045785 1 0.027
homeostatic process GO:0042592 142 0.027
extrinsic apoptotic signaling pathway GO:0097191 3 0.027
negative regulation of catabolic process GO:0009895 3 0.027
protein acetylation GO:0006473 2 0.027
regulation of localization GO:0032879 104 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
angiogenesis GO:0001525 158 0.027
regulation of cell killing GO:0031341 2 0.027
aromatic compound biosynthetic process GO:0019438 217 0.026
Human
regulation of protein localization to nucleus GO:1900180 2 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
cell part morphogenesis GO:0032990 246 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
regulation of protein targeting GO:1903533 2 0.025
sensory system development GO:0048880 76 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
cell cycle GO:0007049 93 0.025
reactive oxygen species biosynthetic process GO:1903409 1 0.025
endoplasmic reticulum unfolded protein response GO:0030968 2 0.025
Mouse
b cell mediated immunity GO:0019724 3 0.025
regulation of response to nutrient levels GO:0032107 1 0.025
negative regulation of cellular catabolic process GO:0031330 3 0.025
lateral line system development GO:0048925 76 0.025
cellular protein metabolic process GO:0044267 129 0.024
complement activation GO:0006956 3 0.024
type i interferon production GO:0032606 2 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.024
negative regulation of metabolic process GO:0009892 86 0.024
Human
regulation of dendrite development GO:0050773 3 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
cellular biosynthetic process GO:0044249 286 0.024
Human Mouse
cellular response to unfolded protein GO:0034620 2 0.024
Mouse
regionalization GO:0003002 274 0.023
hormone transport GO:0009914 2 0.023
post embryonic morphogenesis GO:0009886 4 0.023
response to topologically incorrect protein GO:0035966 2 0.023
Mouse
regulation of cellular component organization GO:0051128 86 0.023
Mouse
cellular amine metabolic process GO:0044106 2 0.023
regulation of hormone secretion GO:0046883 2 0.023
amino acid transport GO:0006865 2 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
Mouse
response to ketone GO:1901654 1 0.023
hemopoiesis GO:0030097 183 0.022
Mouse
membrane fusion GO:0061025 2 0.022
nitric oxide biosynthetic process GO:0006809 2 0.022
regulation of synapse organization GO:0050807 3 0.022
membrane lipid biosynthetic process GO:0046467 2 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
nuclear import GO:0051170 3 0.022
embryonic skeletal system development GO:0048706 97 0.022
regulation of biosynthetic process GO:0009889 250 0.022
Human
gtp metabolic process GO:0046039 4 0.022
stem cell division GO:0017145 1 0.022
neuron differentiation GO:0030182 353 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
regulation of wound healing GO:0061041 2 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
regulation of binding GO:0051098 3 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
Mouse
organelle organization GO:0006996 227 0.022
positive regulation of immune effector process GO:0002699 3 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.021
cell substrate adhesion GO:0031589 4 0.021
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
synaptic target recognition GO:0008039 1 0.021
hatching GO:0035188 4 0.021
anterior posterior pattern specification GO:0009952 152 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
nitrogen compound metabolic process GO:0006807 319 0.020
Human
urogenital system development GO:0001655 97 0.020
response to drug GO:0042493 3 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
positive regulation of cellular process GO:0048522 201 0.020
Human Mouse
muscle tissue development GO:0060537 110 0.020
transport GO:0006810 220 0.020
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.020
Human
regulation of phospholipase activity GO:0010517 2 0.020
negative regulation of nuclear division GO:0051784 3 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
astrocyte differentiation GO:0048708 1 0.020
dna templated transcription initiation GO:0006352 1 0.020
nitric oxide metabolic process GO:0046209 2 0.020
alpha amino acid metabolic process GO:1901605 3 0.020
regulation of cell cycle GO:0051726 52 0.020
lateral line development GO:0048882 66 0.019
vasculature development GO:0001944 278 0.019
modification by symbiont of host morphology or physiology GO:0044003 4 0.019
stem cell maintenance GO:0019827 4 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
locomotion GO:0040011 313 0.019
retina morphogenesis in camera type eye GO:0060042 79 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
ear development GO:0043583 127 0.019
long chain fatty acid metabolic process GO:0001676 1 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
forebrain development GO:0030900 96 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
Mouse
modification of morphology or physiology of other organism GO:0035821 4 0.018
cell killing GO:0001906 2 0.018
organelle fusion GO:0048284 3 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
gtp catabolic process GO:0006184 2 0.018
sensory organ morphogenesis GO:0090596 200 0.018
muscle structure development GO:0061061 196 0.018
positive regulation of cell substrate adhesion GO:0010811 1 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
Human
generation of neurons GO:0048699 385 0.018
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.018
myeloid cell differentiation GO:0030099 86 0.018
tissue remodeling GO:0048771 4 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
Human
cell aging GO:0007569 2 0.018
modulation by virus of host morphology or physiology GO:0019048 1 0.018
endosomal transport GO:0016197 2 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
Human
single organism nuclear import GO:1902593 3 0.018
regulation of cell activation GO:0050865 1 0.017
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.017
positive regulation of epithelial cell proliferation GO:0050679 1 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
eye morphogenesis GO:0048592 144 0.017
segmentation GO:0035282 97 0.017
cellular response to organic substance GO:0071310 105 0.017
Mouse
peptidyl serine modification GO:0018209 2 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
localization of cell GO:0051674 244 0.017
very long chain fatty acid biosynthetic process GO:0042761 4 0.017
regulation of translational initiation GO:0006446 1 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
organonitrogen compound metabolic process GO:1901564 74 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
brain development GO:0007420 293 0.016
response to unfolded protein GO:0006986 2 0.016
Mouse
protein homooligomerization GO:0051260 3 0.016
single organism metabolic process GO:0044710 217 0.016
Human Mouse
production of molecular mediator of immune response GO:0002440 2 0.016
pyruvate metabolic process GO:0006090 1 0.016
long chain fatty acid biosynthetic process GO:0042759 1 0.016
single organism localization GO:1902578 225 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.016
spermatid development GO:0007286 2 0.016
regulation of dna replication GO:0006275 3 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
Human
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
protein import into nucleus GO:0006606 3 0.016
negative regulation of reproductive process GO:2000242 3 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
ovulation cycle GO:0042698 2 0.016
microtubule organizing center organization GO:0031023 1 0.016
cellular component disassembly GO:0022411 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.016
regulation of protein catabolic process GO:0042176 1 0.016
positive regulation of secretion GO:0051047 1 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
negative regulation of programmed cell death GO:0043069 58 0.016
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
embryonic viscerocranium morphogenesis GO:0048703 52 0.016
cell death GO:0008219 121 0.016
Mouse
striated muscle tissue development GO:0014706 110 0.016
positive regulation of metabolic process GO:0009893 108 0.016
Human Mouse
superoxide metabolic process GO:0006801 2 0.016
positive regulation of cellular metabolic process GO:0031325 94 0.016
Human Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
cellular component biogenesis GO:0044085 178 0.016
Mouse
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
adult behavior GO:0030534 2 0.016
estrogen metabolic process GO:0008210 2 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
Human
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
rna localization GO:0006403 4 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
carbohydrate homeostasis GO:0033500 1 0.015
membrane invagination GO:0010324 1 0.015
positive regulation of cell division GO:0051781 2 0.015
adherens junction organization GO:0034332 4 0.015
programmed cell death GO:0012501 119 0.015
Mouse
cellular response to starvation GO:0009267 1 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
organism emergence from protective structure GO:0071684 4 0.015
protein secretion GO:0009306 1 0.015
skeletal system morphogenesis GO:0048705 102 0.014
synaptic vesicle localization GO:0097479 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
regulation of molecular function GO:0065009 70 0.014
Human
negative regulation of cell death GO:0060548 60 0.014
Mouse
establishment of synaptic vesicle localization GO:0097480 1 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
Human
phagocytosis engulfment GO:0006911 1 0.014
response to hydrogen peroxide GO:0042542 3 0.014
macroautophagy GO:0016236 1 0.014
translational initiation GO:0006413 3 0.014
gastrulation GO:0007369 208 0.014
cell motility GO:0048870 244 0.014
single organism transport GO:0044765 206 0.014
regulation of protein transport GO:0051223 3 0.014
negative regulation of cytokine production GO:0001818 1 0.014
negative regulation of translation GO:0017148 1 0.014
Human
cell projection morphogenesis GO:0048858 244 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of autophagy GO:0010507 1 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
b cell activation GO:0042113 2 0.014
cellular amide metabolic process GO:0043603 4 0.014
positive regulation of notch signaling pathway GO:0045747 3 0.014
peptide transport GO:0015833 1 0.014
negative regulation of protein complex assembly GO:0031333 1 0.014
ras protein signal transduction GO:0007265 7 0.014
somatic muscle development GO:0007525 4 0.014
positive regulation of leukocyte differentiation GO:1902107 1 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
regulation of response to cytokine stimulus GO:0060759 3 0.014
single organism membrane fusion GO:0044801 2 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
multicellular organismal signaling GO:0035637 22 0.013
antimicrobial humoral response GO:0019730 2 0.013
negative regulation of multi organism process GO:0043901 3 0.013
Human Mouse
peptidyl lysine acetylation GO:0018394 2 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
disruption of cells of other organism GO:0044364 1 0.013
amine metabolic process GO:0009308 2 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
vacuolar transport GO:0007034 2 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
golgi vesicle transport GO:0048193 3 0.013
hard palate development GO:0060022 4 0.013
multicellular organism growth GO:0035264 4 0.013
cellular response to external stimulus GO:0071496 2 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
camera type eye development GO:0043010 222 0.013
collagen metabolic process GO:0032963 2 0.013
leukocyte mediated cytotoxicity GO:0001909 1 0.013
cytoplasm organization GO:0007028 4 0.013
kupffer s vesicle development GO:0070121 50 0.013
regulation of apoptotic process GO:0042981 98 0.013
Mouse
positive regulation of neuron death GO:1901216 1 0.013
sex determination GO:0007530 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
defense response to virus GO:0051607 10 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
response to arsenic containing substance GO:0046685 5 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
synaptic vesicle transport GO:0048489 1 0.013
positive regulation of leukocyte mediated immunity GO:0002705 1 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
regulation of protein binding GO:0043393 3 0.013
cell matrix adhesion GO:0007160 4 0.013
meiotic cell cycle process GO:1903046 3 0.012
fatty acid transport GO:0015908 1 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
Human
regulation of skeletal muscle tissue development GO:0048641 4 0.012
calcium ion import GO:0070509 4 0.012
regulation of transporter activity GO:0032409 2 0.012
neuron projection development GO:0031175 180 0.012
plasminogen activation GO:0031639 3 0.012
regulation of metal ion transport GO:0010959 4 0.012
tyrosine phosphorylation of stat protein GO:0007260 1 0.012
immune effector process GO:0002252 23 0.012
single organism organelle organization GO:1902589 199 0.012
regulation of blood pressure GO:0008217 1 0.012
centrosome organization GO:0051297 1 0.012
secondary metabolic process GO:0019748 3 0.012
neuron projection morphogenesis GO:0048812 161 0.012
protein complex localization GO:0031503 1 0.012
neuroblast proliferation GO:0007405 2 0.012
calcium mediated signaling GO:0019722 2 0.012
camera type eye morphogenesis GO:0048593 108 0.012
protein stabilization GO:0050821 2 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
mechanosensory lateral line system development GO:0048881 49 0.012
negative regulation of nucleic acid templated transcription GO:1903507 45 0.012
atp catabolic process GO:0006200 4 0.012
skeletal muscle organ development GO:0060538 78 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
skeletal system development GO:0001501 181 0.012
peptide metabolic process GO:0006518 1 0.012
cellular protein catabolic process GO:0044257 4 0.012
cellular response to nutrient levels GO:0031669 2 0.012
macromolecular complex disassembly GO:0032984 1 0.012
carbon dioxide transport GO:0015670 3 0.012
positive regulation of cell activation GO:0050867 1 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
establishment of localization in cell GO:0051649 77 0.012
negative regulation of muscle tissue development GO:1901862 2 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
positive regulation of protein kinase b signaling GO:0051897 1 0.012
germ line stem cell division GO:0042078 1 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
cytokinesis GO:0000910 3 0.012
oxoacid metabolic process GO:0043436 31 0.012
protein modification process GO:0036211 100 0.012
response to amine GO:0014075 1 0.012
post golgi vesicle mediated transport GO:0006892 1 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
regulation of cellular component movement GO:0051270 55 0.011
regulation of transport GO:0051049 45 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
ovulation cycle process GO:0022602 2 0.011
regulation of ph GO:0006885 3 0.011
positive regulation of innate immune response GO:0045089 8 0.011
response to amino acid GO:0043200 2 0.011
autophagy GO:0006914 4 0.011
eye development GO:0001654 277 0.011
cellular response to hypoxia GO:0071456 1 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
protein complex disassembly GO:0043241 1 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
regulation of protein metabolic process GO:0051246 56 0.011
Human
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.011
Mouse
regulation of myotube differentiation GO:0010830 2 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
phototransduction GO:0007602 2 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
muscle fiber development GO:0048747 52 0.011
meiosis i GO:0007127 1 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
regulation of type i interferon production GO:0032479 2 0.011
hematopoietic stem cell differentiation GO:0060218 20 0.011
Mouse
regulation of postsynaptic membrane potential GO:0060078 1 0.011
mesenchyme development GO:0060485 127 0.011

pkz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.019
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.012