Danio rerio

11 known processes

nedd1

neural precursor cell expressed, developmentally down-regulated 1

(Aliases: zgc:63491,fb78g03,wu:fb78g03)

nedd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.138
rna modification GO:0009451 2 0.127
meiotic chromosome segregation GO:0045132 3 0.116
meiotic nuclear division GO:0007126 4 0.111
Fly
nucleic acid metabolic process GO:0090304 244 0.099
embryonic organ development GO:0048568 381 0.097
regulation of multicellular organismal development GO:2000026 223 0.090
synaptic growth at neuromuscular junction GO:0051124 2 0.085
heart development GO:0007507 313 0.071
nucleobase containing compound metabolic process GO:0006139 274 0.064
regulation of cell shape GO:0008360 1 0.062
regulation of synapse organization GO:0050807 3 0.061
lipid storage GO:0019915 1 0.060
generation of neurons GO:0048699 385 0.059
chromosome organization involved in meiosis GO:0070192 1 0.059
biosynthetic process GO:0009058 294 0.058
maintenance of location GO:0051235 4 0.057
meiosis i GO:0007127 1 0.057
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.055
embryonic heart tube development GO:0035050 133 0.050
response to nutrient GO:0007584 3 0.049
cellular biosynthetic process GO:0044249 286 0.049
aging GO:0007568 2 0.048
cellular response to external stimulus GO:0071496 2 0.048
regulation of multicellular organismal process GO:0051239 277 0.047
nuclear division GO:0000280 23 0.046
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.045
rna metabolic process GO:0016070 219 0.045
cell morphogenesis GO:0000902 289 0.045
spindle assembly GO:0051225 2 0.044
Fly
signal transduction GO:0007165 455 0.044
regulation of biological quality GO:0065008 263 0.043
regulation of biosynthetic process GO:0009889 250 0.042
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
response to chemical GO:0042221 320 0.042
establishment of protein localization to organelle GO:0072594 4 0.041
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.040
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.040
transcription dna templated GO:0006351 181 0.040
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.039
regulation of response to stimulus GO:0048583 269 0.039
spindle assembly involved in meiosis GO:0090306 1 0.039
Fly
cellular component movement GO:0006928 335 0.039
cell migration GO:0016477 237 0.039
vasculature development GO:0001944 278 0.038
cell motility GO:0048870 244 0.038
regulation of cellular metabolic process GO:0031323 320 0.037
regulation of synapse assembly GO:0051963 3 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.037
regulation of meiotic cell cycle GO:0051445 1 0.037
regulation of developmental process GO:0050793 247 0.037
negative regulation of protein phosphorylation GO:0001933 4 0.036
regulation of signal transduction GO:0009966 225 0.036
phosphorus metabolic process GO:0006793 109 0.034
synaptic target recognition GO:0008039 1 0.034
regulation of multicellular organism growth GO:0040014 4 0.034
digestive system development GO:0055123 289 0.034
enzyme linked receptor protein signaling pathway GO:0007167 106 0.033
meiotic cell cycle process GO:1903046 3 0.033
Fly
regulation of epithelial cell proliferation GO:0050678 3 0.033
tube morphogenesis GO:0035239 349 0.033
regulation of response to external stimulus GO:0032101 31 0.033
erk1 and erk2 cascade GO:0070371 4 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.032
hematopoietic or lymphoid organ development GO:0048534 191 0.031
negative regulation of protein kinase activity GO:0006469 4 0.031
regulation of reproductive process GO:2000241 4 0.031
specification of axis polarity GO:0065001 4 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
female meiotic division GO:0007143 2 0.029
Fly
cognition GO:0050890 1 0.029
localization of cell GO:0051674 244 0.029
oxoacid metabolic process GO:0043436 31 0.029
rna biosynthetic process GO:0032774 181 0.029
negative regulation of nuclear division GO:0051784 3 0.029
nucleic acid templated transcription GO:0097659 181 0.029
mitotic dna integrity checkpoint GO:0044774 4 0.029
positive regulation of cell cycle GO:0045787 3 0.029
cellular component biogenesis GO:0044085 178 0.028
Fly
organelle organization GO:0006996 227 0.028
Fly
chemotaxis GO:0006935 104 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
regulation of protein targeting GO:1903533 2 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
response to carbohydrate GO:0009743 3 0.027
heterocycle metabolic process GO:0046483 290 0.027
heart process GO:0003015 71 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
regulation of protein binding GO:0043393 3 0.027
regulation of primary metabolic process GO:0080090 311 0.026
proteasomal protein catabolic process GO:0010498 2 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
epithelial tube morphogenesis GO:0060562 148 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
mitotic cell cycle GO:0000278 64 0.025
Fly
b cell activation GO:0042113 2 0.025
negative regulation of multicellular organismal process GO:0051241 69 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
pronuclear migration GO:0035046 1 0.025
negative regulation of kinase activity GO:0033673 4 0.025
g1 s transition of mitotic cell cycle GO:0000082 1 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
phagocytosis GO:0006909 3 0.025
macromolecule biosynthetic process GO:0009059 227 0.024
regulation of mitotic cell cycle embryonic GO:0009794 2 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
mitochondrion organization GO:0007005 4 0.024
blood vessel development GO:0001568 246 0.024
amine metabolic process GO:0009308 2 0.024
digestive tract development GO:0048565 265 0.024
gene expression GO:0010467 252 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
cellular response to nutrient levels GO:0031669 2 0.023
muscle cell migration GO:0014812 4 0.023
regulation of dna replication GO:0006275 3 0.023
response to glucose GO:0009749 3 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.023
regulation of stem cell proliferation GO:0072091 2 0.023
stem cell division GO:0017145 1 0.023
chemosensory behavior GO:0007635 1 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
regulation of anatomical structure morphogenesis GO:0022603 130 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
sprouting angiogenesis GO:0002040 53 0.022
positive regulation of biological process GO:0048518 253 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
regulation of gene expression GO:0010468 265 0.022
response to external stimulus GO:0009605 264 0.022
neuron differentiation GO:0030182 353 0.022
proximal distal pattern formation GO:0009954 1 0.022
organic substance biosynthetic process GO:1901576 289 0.022
locomotion GO:0040011 313 0.021
nuclear transport GO:0051169 4 0.021
histone phosphorylation GO:0016572 2 0.021
positive regulation of cellular metabolic process GO:0031325 94 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
mitotic cell cycle embryonic GO:0045448 2 0.021
peptidyl serine phosphorylation GO:0018105 1 0.021
protein localization to nucleus GO:0034504 3 0.021
negative regulation of protein transport GO:0051224 3 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
regulation of erk1 and erk2 cascade GO:0070372 4 0.021
positive regulation of transcription dna templated GO:0045893 57 0.021
cell projection morphogenesis GO:0048858 244 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
regulation of chemotaxis GO:0050920 18 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
peptidyl threonine modification GO:0018210 1 0.020
response to hexose GO:0009746 3 0.020
cell part morphogenesis GO:0032990 246 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
cell projection organization GO:0030030 284 0.020
regulation of oocyte development GO:0060281 3 0.020
hormone transport GO:0009914 2 0.020
peptidyl serine modification GO:0018209 2 0.020
regulation of apoptotic process GO:0042981 98 0.020
protein targeting to vacuole GO:0006623 1 0.020
reflex GO:0060004 2 0.020
cellular response to light stimulus GO:0071482 4 0.020
multicellular organism growth GO:0035264 4 0.020
protein import into nucleus GO:0006606 3 0.020
protein secretion GO:0009306 1 0.019
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.019
cellular ketone metabolic process GO:0042180 11 0.019
peptide transport GO:0015833 1 0.019
positive regulation of catabolic process GO:0009896 4 0.019
positive regulation of transport GO:0051050 2 0.019
neurological system process GO:0050877 62 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
response to uv GO:0009411 3 0.019
organic acid metabolic process GO:0006082 31 0.019
regulation of response to biotic stimulus GO:0002831 2 0.019
reciprocal dna recombination GO:0035825 1 0.019
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.019
sister chromatid cohesion GO:0007062 2 0.019
cellular response to radiation GO:0071478 4 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
regulation of cell communication GO:0010646 232 0.019
response to monosaccharide GO:0034284 3 0.019
cell aging GO:0007569 2 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
specification of symmetry GO:0009799 204 0.018
regulation of binding GO:0051098 3 0.018
nuclear import GO:0051170 3 0.018
single organism organelle organization GO:1902589 199 0.018
Fly
cell cycle g1 s phase transition GO:0044843 1 0.018
gtp catabolic process GO:0006184 2 0.018
wnt signaling pathway GO:0016055 80 0.018
angiogenesis GO:0001525 158 0.018
regulation of signaling GO:0023051 235 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
neuron projection development GO:0031175 180 0.018
circulatory system process GO:0003013 87 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.018
intracellular signal transduction GO:0035556 85 0.018
convergent extension GO:0060026 118 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
phosphorylation GO:0016310 69 0.017
skeletal muscle organ development GO:0060538 78 0.017
negative regulation of biological process GO:0048519 304 0.017
positive regulation of oocyte development GO:0060282 1 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.017
taxis GO:0042330 109 0.017
regulation of rna metabolic process GO:0051252 224 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
regulation of cell cycle GO:0051726 52 0.017
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
heart morphogenesis GO:0003007 156 0.016
meiotic spindle organization GO:0000212 1 0.016
Fly
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
cellular component morphogenesis GO:0032989 336 0.016
positive regulation of metabolic process GO:0009893 108 0.016
regulation of bmp signaling pathway GO:0030510 39 0.016
cellular amine metabolic process GO:0044106 2 0.016
growth GO:0040007 174 0.016
single organism localization GO:1902578 225 0.016
regulation of protein complex assembly GO:0043254 3 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
positive regulation of secretion GO:0051047 1 0.016
death GO:0016265 121 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
regulation of protein transport GO:0051223 3 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
negative regulation of cell death GO:0060548 60 0.015
mitotic sister chromatid segregation GO:0000070 6 0.015
stem cell maintenance GO:0019827 4 0.015
blood vessel morphogenesis GO:0048514 216 0.015
single organism nuclear import GO:1902593 3 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
response to stress GO:0006950 263 0.015
spindle assembly involved in female meiosis GO:0007056 1 0.015
Fly
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
cytokinesis GO:0000910 3 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
cell substrate adhesion GO:0031589 4 0.015
heart looping GO:0001947 94 0.015
regionalization GO:0003002 274 0.015
protein import GO:0017038 3 0.015
meiosis ii GO:0007135 1 0.015
cellular response to starvation GO:0009267 1 0.015
protein targeting to nucleus GO:0044744 3 0.015
axon development GO:0061564 166 0.015
developmental programmed cell death GO:0010623 4 0.015
regulation of embryonic development GO:0045995 47 0.014
translational initiation GO:0006413 3 0.014
cellular component assembly GO:0022607 170 0.014
Fly
determination of left right symmetry GO:0007368 179 0.014
regulation of metabolic process GO:0019222 359 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
negative chemotaxis GO:0050919 1 0.014
apoptotic process GO:0006915 116 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
neuroblast proliferation GO:0007405 2 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
gastrulation GO:0007369 208 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
regulation of jak stat cascade GO:0046425 3 0.014
regulation of transcription dna templated GO:0006355 213 0.014
synapsis GO:0007129 1 0.014
neuron development GO:0048666 262 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
neurotransmitter transport GO:0006836 2 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
Fly
single fertilization GO:0007338 3 0.013
adult behavior GO:0030534 2 0.013
b cell differentiation GO:0030183 1 0.013
stem cell proliferation GO:0072089 4 0.013
heart contraction GO:0060047 71 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
regulation of oligodendrocyte differentiation GO:0048713 1 0.013
skin development GO:0043588 54 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
male meiosis GO:0007140 2 0.013
single organism metabolic process GO:0044710 217 0.013
establishment of localization GO:0051234 244 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
neuron projection morphogenesis GO:0048812 161 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
cytokinetic process GO:0032506 2 0.013
gtp metabolic process GO:0046039 4 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
histone deacetylation GO:0016575 2 0.013
cell cycle GO:0007049 93 0.013
Fly
establishment of protein localization to vacuole GO:0072666 1 0.012
sensory perception of touch GO:0050975 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
sensory organ morphogenesis GO:0090596 200 0.012
regulation of cellular response to growth factor stimulus GO:0090287 35 0.012
small molecule metabolic process GO:0044281 77 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
membrane invagination GO:0010324 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
immune system process GO:0002376 241 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
protein metabolic process GO:0019538 183 0.012
regulation of cell size GO:0008361 29 0.012
positive regulation of immune effector process GO:0002699 3 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
cell death in response to oxidative stress GO:0036473 2 0.012
bone remodeling GO:0046849 2 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
cellular protein catabolic process GO:0044257 4 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.011
regulation of localization GO:0032879 104 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
somatic muscle development GO:0007525 4 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
positive regulation of multi organism process GO:0043902 3 0.011
secondary metabolic process GO:0019748 3 0.011
retina development in camera type eye GO:0060041 146 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
pore complex assembly GO:0046931 2 0.011
positive regulation of cellular process GO:0048522 201 0.011
cell fate specification GO:0001708 68 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
reciprocal meiotic recombination GO:0007131 1 0.011
atp catabolic process GO:0006200 4 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
bmp signaling pathway GO:0030509 52 0.011
female sex differentiation GO:0046660 4 0.011
negative regulation of chemotaxis GO:0050922 4 0.011
axon extension GO:0048675 45 0.011
protein polymerization GO:0051258 4 0.011
cell fate commitment GO:0045165 99 0.011
protein phosphorylation GO:0006468 47 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
mitochondrial transport GO:0006839 2 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
positive regulation of cytokine production GO:0001819 2 0.011
cellular amide metabolic process GO:0043603 4 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.010
insulin like growth factor receptor signaling pathway GO:0048009 4 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
programmed cell death GO:0012501 119 0.010
response to antibiotic GO:0046677 1 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
kidney development GO:0001822 92 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
regulation of locomotion GO:0040012 55 0.010
negative regulation of defense response GO:0031348 2 0.010
cell cycle g2 m phase transition GO:0044839 4 0.010

nedd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.014
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
nervous system disease DOID:863 0 0.014
eye disease DOID:5614 0 0.014
disease of metabolism DOID:0014667 0 0.011
lysosomal storage disease DOID:3211 0 0.011
inherited metabolic disorder DOID:655 0 0.011