Danio rerio

0 known processes

rasgef1ba

RasGEF domain family, member 1Ba

(Aliases: wu:fi18a09,rasgef1b,zgc:66487)

rasgef1ba biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
head development GO:0060322 303 0.876
brain development GO:0007420 293 0.645
central nervous system development GO:0007417 387 0.622
regulation of developmental process GO:0050793 247 0.506
regulation of multicellular organismal development GO:2000026 223 0.471
regulation of response to stimulus GO:0048583 269 0.425
signal transduction GO:0007165 455 0.356
regulation of macromolecule biosynthetic process GO:0010556 225 0.320
regulation of embryonic development GO:0045995 47 0.317
regulation of primary metabolic process GO:0080090 311 0.298
cell surface receptor signaling pathway GO:0007166 325 0.296
chordate embryonic development GO:0043009 271 0.286
organic cyclic compound biosynthetic process GO:1901362 223 0.278
regulation of cell communication GO:0010646 232 0.266
cellular biosynthetic process GO:0044249 286 0.253
regulation of rna metabolic process GO:0051252 224 0.248
gene expression GO:0010467 252 0.246
digestive system development GO:0055123 289 0.238
regulation of multicellular organismal process GO:0051239 277 0.229
adult behavior GO:0030534 2 0.229
regulation of synapse assembly GO:0051963 3 0.221
regionalization GO:0003002 274 0.215
aromatic compound biosynthetic process GO:0019438 217 0.212
regulation of cell differentiation GO:0045595 142 0.209
enzyme linked receptor protein signaling pathway GO:0007167 106 0.202
multicellular organism growth GO:0035264 4 0.195
rna biosynthetic process GO:0032774 181 0.186
regulation of biological quality GO:0065008 263 0.185
regulation of gene expression GO:0010468 265 0.183
regulation of signaling GO:0023051 235 0.179
organic acid metabolic process GO:0006082 31 0.178
cognition GO:0050890 1 0.177
regulation of cellular metabolic process GO:0031323 320 0.175
segmentation GO:0035282 97 0.164
negative regulation of biological process GO:0048519 304 0.163
meiosis i GO:0007127 1 0.149
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.148
regulation of dendrite morphogenesis GO:0048814 3 0.146
nucleobase containing compound biosynthetic process GO:0034654 205 0.146
negative regulation of cellular process GO:0048523 283 0.145
regulation of oligodendrocyte differentiation GO:0048713 1 0.138
neuron differentiation GO:0030182 353 0.137
regulation of cardiac muscle tissue development GO:0055024 1 0.135
nucleic acid metabolic process GO:0090304 244 0.134
muscle cell differentiation GO:0042692 139 0.134
regulation of nervous system development GO:0051960 90 0.132
cell proliferation GO:0008283 80 0.126
keratinocyte differentiation GO:0030216 0 0.126
negative regulation of signaling GO:0023057 96 0.122
stem cell maintenance GO:0019827 4 0.121
regulation of cell development GO:0060284 100 0.121
regulation of nitrogen compound metabolic process GO:0051171 251 0.120
regulation of multicellular organism growth GO:0040014 4 0.119
regulation of neuron projection development GO:0010975 40 0.118
mitotic cell cycle embryonic GO:0045448 2 0.118
cellular response to organic substance GO:0071310 105 0.115
nitrogen compound metabolic process GO:0006807 319 0.114
negative regulation of cell communication GO:0010648 96 0.109
regulation of neurogenesis GO:0050767 87 0.109
synaptic growth at neuromuscular junction GO:0051124 2 0.107
regulation of signal transduction GO:0009966 225 0.104
regulation of macromolecule metabolic process GO:0060255 317 0.102
cellular nitrogen compound biosynthetic process GO:0044271 218 0.102
regulation of nucleic acid templated transcription GO:1903506 213 0.099
growth GO:0040007 174 0.095
regulation of stem cell proliferation GO:0072091 2 0.095
positive regulation of nervous system development GO:0051962 25 0.095
transcription dna templated GO:0006351 181 0.091
cellular protein catabolic process GO:0044257 4 0.088
lipid storage GO:0019915 1 0.085
embryonic organ morphogenesis GO:0048562 274 0.085
cellular component morphogenesis GO:0032989 336 0.083
organelle organization GO:0006996 227 0.083
positive regulation of catabolic process GO:0009896 4 0.075
cellular component movement GO:0006928 335 0.074
nucleobase containing compound metabolic process GO:0006139 274 0.074
nucleic acid templated transcription GO:0097659 181 0.073
tube morphogenesis GO:0035239 349 0.072
regulation of neuron differentiation GO:0045664 56 0.069
regulation of rna biosynthetic process GO:2001141 213 0.069
gastrulation GO:0007369 208 0.069
regulation of synapse organization GO:0050807 3 0.069
meiotic nuclear division GO:0007126 4 0.068
locomotion GO:0040011 313 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.066
transcription from rna polymerase ii promoter GO:0006366 80 0.066
morphogenesis of an epithelium GO:0002009 333 0.063
generation of neurons GO:0048699 385 0.060
regulation of mitotic cell cycle embryonic GO:0009794 2 0.059
cellular nitrogen compound metabolic process GO:0034641 290 0.058
regulation of metabolic process GO:0019222 359 0.057
meiotic cell cycle process GO:1903046 3 0.057
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.055
alpha amino acid metabolic process GO:1901605 3 0.055
mesenchyme development GO:0060485 127 0.054
endocardial cushion formation GO:0003272 2 0.054
cell fate specification GO:0001708 68 0.053
negative regulation of cellular metabolic process GO:0031324 77 0.053
negative regulation of biosynthetic process GO:0009890 55 0.053
heterocycle metabolic process GO:0046483 290 0.052
response to nitrogen compound GO:1901698 19 0.051
negative regulation of cell differentiation GO:0045596 46 0.050
digestive tract morphogenesis GO:0048546 231 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.049
organic substance biosynthetic process GO:1901576 289 0.049
locomotory behavior GO:0007626 34 0.048
proteasomal protein catabolic process GO:0010498 2 0.048
negative regulation of synapse assembly GO:0051964 2 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.045
regulation of glial cell differentiation GO:0045685 4 0.045
cell part morphogenesis GO:0032990 246 0.045
skeletal system development GO:0001501 181 0.044
multi organism reproductive process GO:0044703 36 0.044
positive regulation of biological process GO:0048518 253 0.044
cell projection morphogenesis GO:0048858 244 0.042
cell projection organization GO:0030030 284 0.042
negative regulation of rna biosynthetic process GO:1902679 45 0.041
rna metabolic process GO:0016070 219 0.041
biosynthetic process GO:0009058 294 0.040
cell fate commitment GO:0045165 99 0.038
ubiquitin dependent protein catabolic process GO:0006511 3 0.038
neural tube development GO:0021915 62 0.037
regulation of neural precursor cell proliferation GO:2000177 3 0.037
cell migration to the midline involved in heart development GO:0003318 12 0.037
death GO:0016265 121 0.037
negative regulation of cellular biosynthetic process GO:0031327 55 0.037
negative regulation of developmental process GO:0051093 65 0.036
forebrain development GO:0030900 96 0.036
localization of cell GO:0051674 244 0.036
heterocycle biosynthetic process GO:0018130 215 0.035
monovalent inorganic cation transport GO:0015672 42 0.035
cellular macromolecule biosynthetic process GO:0034645 224 0.035
regulation of cellular biosynthetic process GO:0031326 245 0.035
homologous chromosome segregation GO:0045143 1 0.035
cellular response to radiation GO:0071478 4 0.034
developmental growth GO:0048589 166 0.034
embryonic organ development GO:0048568 381 0.034
intracellular receptor signaling pathway GO:0030522 30 0.034
positive regulation of neurogenesis GO:0050769 24 0.034
mitochondrion organization GO:0007005 4 0.034
regulation of developmental growth GO:0048638 38 0.034
embryo development ending in birth or egg hatching GO:0009792 271 0.033
maintenance of location GO:0051235 4 0.033
cell cell signaling GO:0007267 52 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.033
negative regulation of signal transduction GO:0009968 94 0.032
peptide metabolic process GO:0006518 1 0.032
modification dependent macromolecule catabolic process GO:0043632 3 0.032
paraxial mesoderm development GO:0048339 8 0.031
apoptotic process GO:0006915 116 0.031
protein metabolic process GO:0019538 183 0.031
cell migration GO:0016477 237 0.031
neuroblast proliferation GO:0007405 2 0.031
ameboidal type cell migration GO:0001667 143 0.030
neuron neuron synaptic transmission GO:0007270 1 0.030
nucleic acid transport GO:0050657 2 0.030
regulation of biosynthetic process GO:0009889 250 0.030
regulation of dendrite development GO:0050773 3 0.030
eye development GO:0001654 277 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
cell death GO:0008219 121 0.029
regulation of protein metabolic process GO:0051246 56 0.029
system process GO:0003008 185 0.029
somite development GO:0061053 96 0.029
regulation of protein binding GO:0043393 3 0.029
neural crest cell differentiation GO:0014033 72 0.028
mitotic cell cycle GO:0000278 64 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
regulation of cell activation GO:0050865 1 0.028
cellular modified amino acid metabolic process GO:0006575 3 0.028
cellular response to extracellular stimulus GO:0031668 2 0.027
water homeostasis GO:0030104 4 0.027
positive regulation of signaling GO:0023056 56 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
cell motility GO:0048870 244 0.026
lipid metabolic process GO:0006629 52 0.026
nuclear import GO:0051170 3 0.026
positive regulation of metabolic process GO:0009893 108 0.025
regulation of transcription dna templated GO:0006355 213 0.025
vasculature development GO:0001944 278 0.025
modification dependent protein catabolic process GO:0019941 3 0.025
regulation of protein catabolic process GO:0042176 1 0.025
anterior posterior pattern specification GO:0009952 152 0.025
telencephalon development GO:0021537 14 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.025
single organism metabolic process GO:0044710 217 0.025
mesenchymal cell differentiation GO:0048762 87 0.024
neurological system process GO:0050877 62 0.024
response to chemical GO:0042221 320 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
tube closure GO:0060606 1 0.024
mesoderm development GO:0007498 88 0.024
response to organic substance GO:0010033 153 0.024
regulation of organ morphogenesis GO:2000027 35 0.024
cellular response to nitrogen compound GO:1901699 6 0.023
regulation of growth GO:0040008 42 0.022
regulation of localization GO:0032879 104 0.022
mesenchyme morphogenesis GO:0072132 5 0.022
striated muscle cell differentiation GO:0051146 129 0.022
negative regulation of cytokine production GO:0001818 1 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
heart development GO:0007507 313 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.022
oxoacid metabolic process GO:0043436 31 0.021
neuron projection morphogenesis GO:0048812 161 0.021
cellular response to hypoxia GO:0071456 1 0.021
neural crest cell fate specification GO:0014036 5 0.020
response to oxygen containing compound GO:1901700 55 0.020
positive regulation of embryonic development GO:0040019 3 0.020
apical junction assembly GO:0043297 1 0.020
cellular component biogenesis GO:0044085 178 0.020
meiotic spindle organization GO:0000212 1 0.020
response to oxidative stress GO:0006979 11 0.020
regulation of receptor mediated endocytosis GO:0048259 4 0.020
macromolecular complex assembly GO:0065003 35 0.020
developmental maturation GO:0021700 34 0.020
positive regulation of leukocyte differentiation GO:1902107 1 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.019
embryonic skeletal system morphogenesis GO:0048704 93 0.019
blood circulation GO:0008015 87 0.019
chemosensory behavior GO:0007635 1 0.019
protein modification process GO:0036211 100 0.019
primary neural tube formation GO:0014020 1 0.019
response to light stimulus GO:0009416 46 0.019
cellular localization GO:0051641 97 0.019
sensory organ morphogenesis GO:0090596 200 0.018
estrogen metabolic process GO:0008210 2 0.018
nuclear transport GO:0051169 4 0.018
sensory perception GO:0007600 39 0.018
cellular response to nutrient levels GO:0031669 2 0.018
regulation of cellular component organization GO:0051128 86 0.018
somitogenesis GO:0001756 87 0.018
cellular response to external stimulus GO:0071496 2 0.018
spindle assembly GO:0051225 2 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
desmosome assembly GO:0002159 2 0.017
positive regulation of cellular process GO:0048522 201 0.017
cellular protein modification process GO:0006464 100 0.017
response to growth factor GO:0070848 39 0.017
regulation of cell projection organization GO:0031344 44 0.017
regulation of heart growth GO:0060420 2 0.017
autophagy GO:0006914 4 0.017
cellular response to oxygen levels GO:0071453 1 0.016
negative regulation of stem cell differentiation GO:2000737 2 0.016
cellular component disassembly GO:0022411 1 0.016
regulation of apoptotic process GO:0042981 98 0.016
regulation of muscle contraction GO:0006937 3 0.016
neuron projection development GO:0031175 180 0.016
fertilization GO:0009566 3 0.016
negative regulation of protein transport GO:0051224 3 0.016
digestive tract development GO:0048565 265 0.016
nucleocytoplasmic transport GO:0006913 4 0.015
positive regulation of neural precursor cell proliferation GO:2000179 1 0.015
ventricular cardiac muscle tissue development GO:0003229 3 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
regulation of dna templated transcription in response to stress GO:0043620 0 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
regulation of eye photoreceptor cell development GO:0042478 2 0.015
negative regulation of multicellular organismal process GO:0051241 69 0.015
neural crest cell development GO:0014032 62 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
regulation of cellular response to growth factor stimulus GO:0090287 35 0.015
regulation of programmed cell death GO:0043067 101 0.015
cellular response to stress GO:0033554 62 0.015
regulation of neurological system process GO:0031644 2 0.015
determination of bilateral symmetry GO:0009855 204 0.014
aging GO:0007568 2 0.014
dna biosynthetic process GO:0071897 3 0.014
regulation of cell migration GO:0030334 40 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
negative regulation of tor signaling GO:0032007 2 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
smooth muscle tissue development GO:0048745 1 0.014
cellular response to organic cyclic compound GO:0071407 38 0.014
regulation of organ growth GO:0046620 3 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
cartilage morphogenesis GO:0060536 13 0.014
synaptic vesicle localization GO:0097479 1 0.014
stem cell development GO:0048864 82 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
endocardial cushion morphogenesis GO:0003203 3 0.014
cellular lipid metabolic process GO:0044255 36 0.014
single organism organelle organization GO:1902589 199 0.014
skeletal muscle fiber development GO:0048741 35 0.014
centrosome duplication GO:0051298 1 0.014
negative regulation of gene expression GO:0010629 65 0.014
regulation of system process GO:0044057 40 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
negative regulation of rna metabolic process GO:0051253 48 0.013
positive regulation of glial cell differentiation GO:0045687 1 0.013
positive regulation of gliogenesis GO:0014015 2 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.013
positive regulation of cell development GO:0010720 25 0.013
compound eye development GO:0048749 2 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
reproduction GO:0000003 40 0.013
gliogenesis GO:0042063 45 0.013
specification of symmetry GO:0009799 204 0.013
positive regulation of multi organism process GO:0043902 3 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
neuron development GO:0048666 262 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
modulation by virus of host morphology or physiology GO:0019048 1 0.012
cytoskeleton organization GO:0007010 96 0.012
cellular component assembly GO:0022607 170 0.012
regulation of gliogenesis GO:0014013 6 0.012
positive regulation of cell cycle GO:0045787 3 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
heart looping GO:0001947 94 0.012
determination of left right symmetry GO:0007368 179 0.012
response to nutrient GO:0007584 3 0.012
cartilage development GO:0051216 96 0.012
macromolecule catabolic process GO:0009057 15 0.012
stem cell proliferation GO:0072089 4 0.011
epithelial cell development GO:0002064 42 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
synapse assembly GO:0007416 9 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
foregut morphogenesis GO:0007440 4 0.011
larval behavior GO:0030537 5 0.011
larval development GO:0002164 2 0.011
negative regulation of metabolic process GO:0009892 86 0.011
behavior GO:0007610 74 0.011
positive regulation of gene expression GO:0010628 71 0.011
ear development GO:0043583 127 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
nucleobase containing compound transport GO:0015931 2 0.011
positive regulation of cell division GO:0051781 2 0.011
skeletal system morphogenesis GO:0048705 102 0.010
regulation of binding GO:0051098 3 0.010
hypothalamus cell differentiation GO:0021979 4 0.010
programmed cell death GO:0012501 119 0.010
central nervous system neuron development GO:0021954 29 0.010
positive regulation of chromatin modification GO:1903310 1 0.010
macromolecule localization GO:0033036 54 0.010
regulation of membrane potential GO:0042391 23 0.010
cell maturation GO:0048469 23 0.010
regulation of reproductive process GO:2000241 4 0.010
response to stress GO:0006950 263 0.010

rasgef1ba disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.079
disease of anatomical entity DOID:7 0 0.071
cancer DOID:162 0 0.064
organ system cancer DOID:0050686 0 0.044
cardiovascular system disease DOID:1287 0 0.019
musculoskeletal system disease DOID:17 0 0.014
endocrine gland cancer DOID:170 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
nervous system disease DOID:863 0 0.011