Danio rerio

7 known processes

ccne

cyclin E

(Aliases: cyce,wu:fa18e07,ccne1,fa18e07)

ccne biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic dna integrity checkpoint GO:0044774 4 0.641
larval development GO:0002164 2 0.516
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.498
Fly
modification dependent protein catabolic process GO:0019941 3 0.472
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.410
Mouse Worm Fly
cellular protein catabolic process GO:0044257 4 0.382
Fly
cytokinesis GO:0000910 3 0.367
organic cyclic compound metabolic process GO:1901360 301 0.318
Mouse Worm Fly
nuclear division GO:0000280 23 0.267
Worm Fly
signal transduction GO:0007165 455 0.247
Mouse Fly
maintenance of location GO:0051235 4 0.229
single organism reproductive process GO:0044702 40 0.204
Worm Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.200
Fly
g2 m transition of mitotic cell cycle GO:0000086 4 0.197
positive regulation of cellular process GO:0048522 201 0.188
Worm Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.186
Fly
macromolecule biosynthetic process GO:0009059 227 0.181
Mouse Worm Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.158
Mouse Worm Fly
chromosome segregation GO:0007059 12 0.154
Fly
biosynthetic process GO:0009058 294 0.151
Mouse Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.142
digestive tract development GO:0048565 265 0.140
regulation of dna replication GO:0006275 3 0.138
Fly
regulation of metabolic process GO:0019222 359 0.138
Mouse Worm Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.126
Fly
digestive system development GO:0055123 289 0.126
regulation of nitrogen compound metabolic process GO:0051171 251 0.125
Fly
mitotic cell cycle GO:0000278 64 0.119
Worm Fly
positive regulation of biological process GO:0048518 253 0.113
Worm Fly
negative regulation of mitotic cell cycle GO:0045930 11 0.110
Worm Fly
spindle assembly involved in meiosis GO:0090306 1 0.107
ubiquitin dependent protein catabolic process GO:0006511 3 0.104
Fly
cell cycle g1 s phase transition GO:0044843 1 0.102
Worm Fly
regulation of mitotic cell cycle phase transition GO:1901990 8 0.100
Fly
stem cell development GO:0048864 82 0.095
Fly
meiotic cell cycle process GO:1903046 3 0.094
establishment of protein localization to organelle GO:0072594 4 0.091
mitotic dna damage checkpoint GO:0044773 4 0.091
regulation of gene expression GO:0010468 265 0.088
Worm Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.087
cell cycle g2 m phase transition GO:0044839 4 0.083
regulation of mitosis GO:0007088 9 0.083
Worm Fly
mitotic cell cycle process GO:1903047 48 0.082
Worm Fly
cellular biosynthetic process GO:0044249 286 0.080
Mouse Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.080
Mouse Worm Fly
nucleic acid metabolic process GO:0090304 244 0.079
Mouse Worm Fly
positive regulation of transport GO:0051050 2 0.079
locomotion GO:0040011 313 0.075
cell proliferation GO:0008283 80 0.075
Worm Fly
ear development GO:0043583 127 0.075
regulation of response to stimulus GO:0048583 269 0.073
regulation of signaling GO:0023051 235 0.071
transport GO:0006810 220 0.070
small molecule metabolic process GO:0044281 77 0.069
sister chromatid segregation GO:0000819 6 0.068
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.067
Mouse Worm Fly
oocyte maturation GO:0001556 4 0.067
cell cycle process GO:0022402 53 0.065
Worm Fly
cytoskeleton organization GO:0007010 96 0.064
heterocycle metabolic process GO:0046483 290 0.064
Mouse Worm Fly
growth GO:0040007 174 0.064
nucleobase containing compound biosynthetic process GO:0034654 205 0.063
Fly
mitotic nuclear division GO:0007067 18 0.063
Worm Fly
meiotic nuclear division GO:0007126 4 0.061
cellular aromatic compound metabolic process GO:0006725 295 0.061
Mouse Worm Fly
cellular macromolecule metabolic process GO:0044260 391 0.061
Human Mouse Worm Fly
mitotic cell cycle phase transition GO:0044772 9 0.061
Worm Fly
protein metabolic process GO:0019538 183 0.061
Human Mouse Worm Fly
spindle assembly GO:0051225 2 0.058
regulation of protein import into nucleus GO:0042306 2 0.057
female meiotic division GO:0007143 2 0.057
positive regulation of metabolic process GO:0009893 108 0.056
regulation of chromosome segregation GO:0051983 1 0.056
Fly
regulation of cell cycle GO:0051726 52 0.056
Mouse Worm Fly
regulation of cell communication GO:0010646 232 0.055
meiosis i GO:0007127 1 0.054
negative regulation of cellular process GO:0048523 283 0.053
Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.052
Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.052
tube morphogenesis GO:0035239 349 0.052
aromatic compound biosynthetic process GO:0019438 217 0.051
Fly
multi organism process GO:0051704 134 0.051
Worm Fly
response to chemical GO:0042221 320 0.051
negative regulation of cell cycle phase transition GO:1901988 5 0.050
Fly
regulation of cellular metabolic process GO:0031323 320 0.048
Mouse Worm Fly
developmental process involved in reproduction GO:0003006 27 0.047
Worm Fly
positive regulation of cellular metabolic process GO:0031325 94 0.047
organonitrogen compound metabolic process GO:1901564 74 0.046
regulation of primary metabolic process GO:0080090 311 0.046
Mouse Worm Fly
regulation of developmental process GO:0050793 247 0.044
Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.044
aging GO:0007568 2 0.044
negative regulation of biological process GO:0048519 304 0.044
Worm Fly
single organism organelle organization GO:1902589 199 0.043
Worm Fly
oxoacid metabolic process GO:0043436 31 0.042
single organism metabolic process GO:0044710 217 0.042
Worm Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.041
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.041
Fly
organic acid metabolic process GO:0006082 31 0.041
organelle organization GO:0006996 227 0.041
Worm Fly
proteasomal protein catabolic process GO:0010498 2 0.040
Fly
heterocycle biosynthetic process GO:0018130 215 0.040
Fly
response to external stimulus GO:0009605 264 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
Worm
carboxylic acid metabolic process GO:0019752 22 0.039
cleavage furrow formation GO:0036089 2 0.039
meiotic spindle organization GO:0000212 1 0.039
nuclear import GO:0051170 3 0.039
neuron development GO:0048666 262 0.039
regulation of cytoplasmic transport GO:1903649 4 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
organic substance biosynthetic process GO:1901576 289 0.038
Mouse Worm Fly
organelle fission GO:0048285 23 0.037
Worm Fly
heart development GO:0007507 313 0.037
regulation of rna metabolic process GO:0051252 224 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.036
Fly
regulation of meiotic cell cycle GO:0051445 1 0.036
Worm
single organism transport GO:0044765 206 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.036
Mouse Worm Fly
organelle assembly GO:0070925 110 0.035
mitotic g2 m transition checkpoint GO:0044818 3 0.035
regulation of biological quality GO:0065008 263 0.034
Fly
immune system process GO:0002376 241 0.034
germ line stem cell division GO:0042078 1 0.033
regulation of protein localization to nucleus GO:1900180 2 0.033
cellular component biogenesis GO:0044085 178 0.032
development of primary female sexual characteristics GO:0046545 4 0.032
male meiosis GO:0007140 2 0.032
response to organic substance GO:0010033 153 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
Fly
cell growth GO:0016049 57 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.032
cell cycle phase transition GO:0044770 9 0.031
Worm Fly
negative regulation of dna replication GO:0008156 2 0.031
response to uv GO:0009411 3 0.031
cytoskeleton dependent cytokinesis GO:0061640 3 0.031
cell migration involved in gastrulation GO:0042074 79 0.031
gliogenesis GO:0042063 45 0.030
protein polymerization GO:0051258 4 0.030
rna metabolic process GO:0016070 219 0.030
chromosome organization involved in meiosis GO:0070192 1 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.029
mitotic g2 dna damage checkpoint GO:0007095 3 0.029
g2 dna damage checkpoint GO:0031572 3 0.029
regulation of signal transduction GO:0009966 225 0.029
histone phosphorylation GO:0016572 2 0.029
germ cell development GO:0007281 22 0.029
Worm Fly
establishment of localization GO:0051234 244 0.028
convergent extension GO:0060026 118 0.028
meiotic chromosome segregation GO:0045132 3 0.028
regulation of transcription dna templated GO:0006355 213 0.028
regulation of synapse organization GO:0050807 3 0.028
regulation of organelle assembly GO:1902115 4 0.028
spindle assembly involved in mitosis GO:0090307 1 0.027
response to oxygen containing compound GO:1901700 55 0.027
mitotic cell cycle embryonic GO:0045448 2 0.026
regulation of protein catabolic process GO:0042176 1 0.026
Fly
negative regulation of protein localization to nucleus GO:1900181 2 0.026
developmental cell growth GO:0048588 52 0.026
muscle cell differentiation GO:0042692 139 0.026
nuclear transport GO:0051169 4 0.026
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.026
regulation of biosynthetic process GO:0009889 250 0.026
Fly
positive regulation of gene expression GO:0010628 71 0.025
response to wounding GO:0009611 116 0.025
gene expression GO:0010467 252 0.025
Worm Fly
brain development GO:0007420 293 0.025
homeostatic process GO:0042592 142 0.025
regulation of localization GO:0032879 104 0.024
regulation of organelle organization GO:0033043 29 0.024
Worm Fly
guanosine containing compound catabolic process GO:1901069 2 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.024
Fly
regulation of cell cycle process GO:0010564 20 0.024
Worm Fly
cation transport GO:0006812 81 0.024
response to monosaccharide GO:0034284 3 0.023
cellular ketone metabolic process GO:0042180 11 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
Mouse
positive regulation of catabolic process GO:0009896 4 0.023
reproduction GO:0000003 40 0.022
Worm Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.022
single organism nuclear import GO:1902593 3 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
Fly
negative regulation of cell cycle process GO:0010948 9 0.022
Fly
spindle assembly involved in female meiosis GO:0007056 1 0.022
developmental growth GO:0048589 166 0.022
cell cycle checkpoint GO:0000075 7 0.022
multicellular organismal reproductive process GO:0048609 35 0.022
Worm Fly
regulation of growth GO:0040008 42 0.022
mitotic cytokinesis GO:0000281 3 0.022
death GO:0016265 121 0.022
Fly
rna biosynthetic process GO:0032774 181 0.022
regulation of protein ubiquitination GO:0031396 3 0.021
Fly
developmental growth involved in morphogenesis GO:0060560 86 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
Worm Fly
gastrulation GO:0007369 208 0.021
negative regulation of mitosis GO:0045839 3 0.021
Fly
chromosome localization GO:0050000 2 0.021
cellular protein metabolic process GO:0044267 129 0.021
Human Mouse Worm Fly
centrosome cycle GO:0007098 1 0.021
phosphorus metabolic process GO:0006793 109 0.021
regulation of mitotic cell cycle GO:0007346 25 0.021
Worm Fly
homologous chromosome segregation GO:0045143 1 0.020
response to drug GO:0042493 3 0.020
protein import into nucleus GO:0006606 3 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
gtp catabolic process GO:0006184 2 0.019
negative regulation of intracellular transport GO:0032387 3 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
Fly
protein complex assembly GO:0006461 30 0.019
reproductive process GO:0022414 40 0.019
Worm Fly
central nervous system development GO:0007417 387 0.019
positive regulation of chromosome segregation GO:0051984 1 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
digestive tract morphogenesis GO:0048546 231 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
vesicle mediated transport GO:0016192 22 0.018
convergent extension involved in gastrulation GO:0060027 71 0.018
regulation of molecular function GO:0065009 70 0.018
Mouse Worm Fly
negative regulation of protein phosphorylation GO:0001933 4 0.018
circulatory system process GO:0003013 87 0.018
nucleic acid templated transcription GO:0097659 181 0.018
regulation of multicellular organismal process GO:0051239 277 0.017
Worm
ion transport GO:0006811 114 0.017
cell proliferation involved in heart morphogenesis GO:0061323 2 0.017
reproductive structure development GO:0048608 5 0.017
Worm
positive regulation of cellular component biogenesis GO:0044089 3 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
fertilization GO:0009566 3 0.017
protein targeting to nucleus GO:0044744 3 0.016
pancreas development GO:0031016 84 0.016
response to glucocorticoid GO:0051384 1 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
response to glucose GO:0009749 3 0.016
cell migration GO:0016477 237 0.016
cell motility GO:0048870 244 0.015
positive regulation of cell division GO:0051781 2 0.015
neuron differentiation GO:0030182 353 0.015
Fly
response to corticosteroid GO:0031960 1 0.015
cellular component morphogenesis GO:0032989 336 0.015
Fly
response to inorganic substance GO:0010035 38 0.015
peptidyl serine modification GO:0018209 2 0.015
regulation of protein complex assembly GO:0043254 3 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
multi organism reproductive process GO:0044703 36 0.015
Worm Fly
gland development GO:0048732 143 0.015
stem cell division GO:0017145 1 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
cellular component movement GO:0006928 335 0.015
embryonic organ development GO:0048568 381 0.015
determination of left right symmetry GO:0007368 179 0.014
positive regulation of rna biosynthetic process GO:1902680 57 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
regulation of protein targeting GO:1903533 2 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
positive regulation of cell cycle GO:0045787 3 0.014
Worm Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cellular component assembly GO:0022607 170 0.014
regulation of catalytic activity GO:0050790 55 0.014
Mouse Worm Fly
intracellular signal transduction GO:0035556 85 0.014
Fly
inner ear development GO:0048839 126 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
Fly
response to hexose GO:0009746 3 0.014
cellular protein complex assembly GO:0043623 19 0.014
female gonad development GO:0008585 4 0.014
organic substance catabolic process GO:1901575 28 0.013
Fly
single organism localization GO:1902578 225 0.013
kupffer s vesicle development GO:0070121 50 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
convergent extension involved in organogenesis GO:0060029 10 0.013
neuron projection development GO:0031175 180 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
cell maturation GO:0048469 23 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
sensory organ development GO:0007423 393 0.013
Fly
regulation of circadian rhythm GO:0042752 4 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
Worm Fly
negative regulation of signaling GO:0023057 96 0.012
leukocyte homeostasis GO:0001776 2 0.012
protein localization to microtubule cytoskeleton GO:0072698 1 0.012
mesenchyme development GO:0060485 127 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
tissue regeneration GO:0042246 74 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
oocyte development GO:0048599 14 0.012
cell cycle GO:0007049 93 0.012
Mouse Worm Fly
microtubule based process GO:0007017 60 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
striated muscle cell differentiation GO:0051146 129 0.012
wound healing GO:0042060 90 0.012
mitotic cell cycle checkpoint GO:0007093 5 0.012
regulation of cell proliferation GO:0042127 37 0.012
Worm Fly
stem cell maintenance GO:0019827 4 0.012
Fly
epithelial tube morphogenesis GO:0060562 148 0.012
metal ion transport GO:0030001 58 0.012
response to metal ion GO:0010038 34 0.011
cellular catabolic process GO:0044248 27 0.011
Fly
dna metabolic process GO:0006259 27 0.011
Mouse Worm Fly
dna integrity checkpoint GO:0031570 6 0.011
microtubule organizing center organization GO:0031023 1 0.011
mitotic sister chromatid segregation GO:0000070 6 0.011
Fly
blood circulation GO:0008015 87 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
Fly
ribonucleotide metabolic process GO:0009259 27 0.011
single fertilization GO:0007338 3 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.011
Fly
nucleocytoplasmic transport GO:0006913 4 0.011
regulation of protein transport GO:0051223 3 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
cofactor metabolic process GO:0051186 15 0.011
regulation of mrna processing GO:0050684 3 0.011
positive regulation of oocyte development GO:0060282 1 0.011
secondary metabolic process GO:0019748 3 0.011
macromolecule modification GO:0043412 111 0.011
Human Mouse Worm Fly
actin filament based process GO:0030029 64 0.011
protein modification process GO:0036211 100 0.010
Human Mouse Worm Fly
glial cell differentiation GO:0010001 42 0.010
intra s dna damage checkpoint GO:0031573 1 0.010
cellular localization GO:0051641 97 0.010
gtp metabolic process GO:0046039 4 0.010
gamete generation GO:0007276 33 0.010
Worm Fly
multicellular organism reproduction GO:0032504 35 0.010
Worm Fly
regulation of nucleotide catabolic process GO:0030811 2 0.010
translational initiation GO:0006413 3 0.010

ccne disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of anatomical entity DOID:7 0 0.013