Danio rerio

0 known processes

fhl2a

four and a half LIM domains 2a

(Aliases: zgc:92428)

fhl2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component morphogenesis GO:0032989 336 0.130
Worm
neuron differentiation GO:0030182 353 0.125
catechol containing compound metabolic process GO:0009712 2 0.106
cellular component assembly GO:0022607 170 0.104
Worm
determination of bilateral symmetry GO:0009855 204 0.100
positive regulation of transport GO:0051050 2 0.097
organic acid catabolic process GO:0016054 3 0.094
determination of left right symmetry GO:0007368 179 0.092
pigmentation GO:0043473 85 0.090
specification of symmetry GO:0009799 204 0.083
guanosine containing compound metabolic process GO:1901068 4 0.080
determination of heart left right asymmetry GO:0061371 117 0.079
cell migration GO:0016477 237 0.079
locomotion GO:0040011 313 0.069
nuclear transport GO:0051169 4 0.068
neuron projection morphogenesis GO:0048812 161 0.067
cell morphogenesis GO:0000902 289 0.066
cell part morphogenesis GO:0032990 246 0.066
alpha amino acid metabolic process GO:1901605 3 0.064
generation of neurons GO:0048699 385 0.064
regulation of cell shape GO:0008360 1 0.062
digestive system development GO:0055123 289 0.062
embryonic organ morphogenesis GO:0048562 274 0.059
neuron projection development GO:0031175 180 0.058
cell projection morphogenesis GO:0048858 244 0.057
cell motility GO:0048870 244 0.057
response to fluid shear stress GO:0034405 2 0.057
small molecule metabolic process GO:0044281 77 0.055
cell substrate adhesion GO:0031589 4 0.055
segmentation GO:0035282 97 0.054
catechol containing compound biosynthetic process GO:0009713 2 0.054
lipid storage GO:0019915 1 0.053
localization of cell GO:0051674 244 0.051
maintenance of location GO:0051235 4 0.050
catecholamine metabolic process GO:0006584 2 0.046
signal transduction GO:0007165 455 0.045
regulation of protein complex assembly GO:0043254 3 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.044
neuron development GO:0048666 262 0.042
actin polymerization or depolymerization GO:0008154 2 0.042
heart looping GO:0001947 94 0.041
organonitrogen compound metabolic process GO:1901564 74 0.041
cellular component movement GO:0006928 335 0.041
response to endogenous stimulus GO:0009719 83 0.041
Human
cell projection organization GO:0030030 284 0.040
regulation of protein binding GO:0043393 3 0.040
regulation of gtp catabolic process GO:0033124 2 0.040
phenol containing compound biosynthetic process GO:0046189 4 0.038
central nervous system development GO:0007417 387 0.038
response to external stimulus GO:0009605 264 0.038
positive regulation of biological process GO:0048518 253 0.038
heart development GO:0007507 313 0.037
Mouse
protein targeting to nucleus GO:0044744 3 0.037
single organism metabolic process GO:0044710 217 0.037
transport GO:0006810 220 0.036
gtp metabolic process GO:0046039 4 0.036
xenobiotic metabolic process GO:0006805 4 0.036
small molecule catabolic process GO:0044282 3 0.036
digestive tract development GO:0048565 265 0.035
aging GO:0007568 2 0.035
regulation of nucleotide catabolic process GO:0030811 2 0.035
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.035
carboxylic acid catabolic process GO:0046395 3 0.035
regulation of binding GO:0051098 3 0.034
regulation of purine nucleotide catabolic process GO:0033121 2 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.033
Human Mouse
cellular component biogenesis GO:0044085 178 0.033
Worm
chemotaxis GO:0006935 104 0.033
regulation of multicellular organismal development GO:2000026 223 0.032
dopamine metabolic process GO:0042417 2 0.032
axon development GO:0061564 166 0.032
chemosensory behavior GO:0007635 1 0.031
guanosine containing compound catabolic process GO:1901069 2 0.031
single organism nuclear import GO:1902593 3 0.031
regulation of reproductive process GO:2000241 4 0.031
positive regulation of cell activation GO:0050867 1 0.030
indole containing compound metabolic process GO:0042430 2 0.030
regulation of synapse organization GO:0050807 3 0.030
response to chemical GO:0042221 320 0.029
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.029
Human Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.029
negative regulation of protein complex assembly GO:0031333 1 0.029
apical junction assembly GO:0043297 1 0.029
regulation of biological quality GO:0065008 263 0.028
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.028
protein complex disassembly GO:0043241 1 0.028
phagocytosis GO:0006909 3 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
protein localization to plasma membrane GO:0072659 1 0.028
gtp catabolic process GO:0006184 2 0.027
response to alkaloid GO:0043279 2 0.027
establishment of protein localization to plasma membrane GO:0090002 1 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
Human Mouse
regulation of stem cell differentiation GO:2000736 4 0.026
negative regulation of heart contraction GO:0045822 2 0.026
regulation of cell development GO:0060284 100 0.026
muscle cell differentiation GO:0042692 139 0.026
Mouse Worm
regulation of cardiac muscle tissue development GO:0055024 1 0.026
positive regulation of cell adhesion GO:0045785 1 0.026
serotonin metabolic process GO:0042428 1 0.026
positive regulation of reproductive process GO:2000243 2 0.025
embryo development ending in birth or egg hatching GO:0009792 271 0.025
embryonic heart tube morphogenesis GO:0003143 108 0.025
striated muscle cell differentiation GO:0051146 129 0.025
Mouse Worm
sequestering of metal ion GO:0051238 3 0.025
organic acid metabolic process GO:0006082 31 0.025
cellular amino acid biosynthetic process GO:0008652 2 0.025
regulation of cell substrate adhesion GO:0010810 1 0.025
immune system process GO:0002376 241 0.025
leukocyte mediated cytotoxicity GO:0001909 1 0.025
water homeostasis GO:0030104 4 0.024
gamete generation GO:0007276 33 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
Human Mouse
digestive tract morphogenesis GO:0048546 231 0.024
lymphocyte proliferation GO:0046651 1 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
regulation of gtpase activity GO:0043087 2 0.024
protein polymerization GO:0051258 4 0.024
organelle organization GO:0006996 227 0.023
Worm
regulation of oocyte development GO:0060281 3 0.023
response to organic substance GO:0010033 153 0.023
Human
catecholamine biosynthetic process GO:0042423 2 0.023
regulation of bone mineralization GO:0030500 2 0.023
embryonic heart tube development GO:0035050 133 0.023
dopamine biosynthetic process GO:0042416 2 0.023
regulation of cell activation GO:0050865 1 0.023
regionalization GO:0003002 274 0.022
regulation of rho protein signal transduction GO:0035023 2 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
Human Mouse
regulation of sequestering of calcium ion GO:0051282 4 0.022
positive regulation of nucleotide catabolic process GO:0030813 1 0.022
chordate embryonic development GO:0043009 271 0.022
mononuclear cell proliferation GO:0032943 1 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
single organism organelle organization GO:1902589 199 0.022
Worm
regulation of response to stimulus GO:0048583 269 0.022
ear development GO:0043583 127 0.022
regulation of neurotransmitter transport GO:0051588 1 0.021
melanin metabolic process GO:0006582 2 0.021
regulation of protein polymerization GO:0032271 2 0.021
single organism transport GO:0044765 206 0.021
membrane fusion GO:0061025 2 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
Human Mouse
establishment of synaptic vesicle localization GO:0097480 1 0.021
regulation of neurotransmitter secretion GO:0046928 1 0.021
multi organism process GO:0051704 134 0.021
regulation of cell projection assembly GO:0060491 4 0.020
synaptic vesicle transport GO:0048489 1 0.020
regulation of cell communication GO:0010646 232 0.020
ameboidal type cell migration GO:0001667 143 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
Human Mouse
negative regulation of biological process GO:0048519 304 0.020
Human Mouse
leukocyte proliferation GO:0070661 1 0.020
regulation of primary metabolic process GO:0080090 311 0.020
Human Mouse
lipid oxidation GO:0034440 1 0.020
regulation of signal transduction GO:0009966 225 0.020
regulation of dendrite development GO:0050773 3 0.019
neurotransmitter transport GO:0006836 2 0.019
nuclear import GO:0051170 3 0.019
positive regulation of cellular process GO:0048522 201 0.019
cilium organization GO:0044782 71 0.019
stem cell differentiation GO:0048863 117 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.019
convergent extension involved in gastrulation GO:0060027 71 0.019
organelle assembly GO:0070925 110 0.019
Worm
tube morphogenesis GO:0035239 349 0.019
negative regulation of sequestering of calcium ion GO:0051283 4 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
Human Mouse
regulation of organelle assembly GO:1902115 4 0.018
cytokinesis GO:0000910 3 0.018
amine metabolic process GO:0009308 2 0.018
mesenchyme development GO:0060485 127 0.018
synaptic vesicle localization GO:0097479 1 0.018
blood circulation GO:0008015 87 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
adult behavior GO:0030534 2 0.018
heart morphogenesis GO:0003007 156 0.018
Mouse
epithelial tube morphogenesis GO:0060562 148 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
larval development GO:0002164 2 0.018
vitamin a biosynthetic process GO:0035238 1 0.017
single fertilization GO:0007338 3 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
heterocycle metabolic process GO:0046483 290 0.017
Human Mouse
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
myeloid cell development GO:0061515 32 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
activation of mapk activity GO:0000187 3 0.017
heart contraction GO:0060047 71 0.017
protein import GO:0017038 3 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
embryonic organ development GO:0048568 381 0.017
negative regulation of striated muscle tissue development GO:0045843 2 0.017
convergent extension GO:0060026 118 0.017
oxoacid metabolic process GO:0043436 31 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
cell killing GO:0001906 2 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
Worm
regulation of transporter activity GO:0032409 2 0.016
regulation of metabolic process GO:0019222 359 0.016
Human Mouse
taxis GO:0042330 109 0.016
cellular biosynthetic process GO:0044249 286 0.015
Human Mouse
regulation of synaptic plasticity GO:0048167 1 0.015
response to drug GO:0042493 3 0.015
atp catabolic process GO:0006200 4 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
cell substrate junction assembly GO:0007044 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
outflow tract morphogenesis GO:0003151 1 0.015
cellular component disassembly GO:0022411 1 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
Human Mouse
regulation of metal ion transport GO:0010959 4 0.015
hard palate development GO:0060022 4 0.015
heart process GO:0003015 71 0.014
fat soluble vitamin metabolic process GO:0006775 4 0.014
response to glucocorticoid GO:0051384 1 0.014
axonogenesis GO:0007409 152 0.014
cardiac cell development GO:0055006 21 0.014
Mouse
cell projection assembly GO:0030031 64 0.014
phosphorus metabolic process GO:0006793 109 0.014
glial cell differentiation GO:0010001 42 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
tight junction assembly GO:0070830 1 0.014
cognition GO:0050890 1 0.014
circulatory system process GO:0003013 87 0.014
positive regulation of cell substrate adhesion GO:0010811 1 0.014
apoptotic process GO:0006915 116 0.014
Human
neurotransmitter secretion GO:0007269 2 0.014
regulation of cell morphogenesis GO:0022604 42 0.013
cilium morphogenesis GO:0060271 85 0.013
protein metabolic process GO:0019538 183 0.013
smad protein complex assembly GO:0007183 1 0.013
organonitrogen compound biosynthetic process GO:1901566 47 0.013
regulation of filopodium assembly GO:0051489 2 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
response to abiotic stimulus GO:0009628 122 0.013
immune system development GO:0002520 191 0.013
embryonic pattern specification GO:0009880 44 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
Human Mouse
regulation of synapse assembly GO:0051963 3 0.013
establishment of endothelial barrier GO:0061028 3 0.013
cell matrix adhesion GO:0007160 4 0.013
cell cycle arrest GO:0007050 1 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
transmembrane transport GO:0055085 120 0.012
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
Human Mouse
regulation of localization GO:0032879 104 0.012
photoreceptor cell fate commitment GO:0046552 1 0.012
multicellular organism reproduction GO:0032504 35 0.012
spermatid development GO:0007286 2 0.012
positive regulation of multi organism process GO:0043902 3 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
muscle structure development GO:0061061 196 0.012
Mouse Worm
regulation of biomineral tissue development GO:0070167 2 0.012
actin filament based process GO:0030029 64 0.012
Worm
single organism localization GO:1902578 225 0.012
phagocytosis engulfment GO:0006911 1 0.012
mechanosensory behavior GO:0007638 2 0.012
protein localization to nucleus GO:0034504 3 0.012
organic substance biosynthetic process GO:1901576 289 0.012
Human Mouse
regulation of developmental process GO:0050793 247 0.012
cellular response to nutrient levels GO:0031669 2 0.012
positive regulation of catabolic process GO:0009896 4 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
stem cell maintenance GO:0019827 4 0.012
medulla oblongata development GO:0021550 4 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
myotube differentiation GO:0014902 45 0.012
response to ketone GO:1901654 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of neuron differentiation GO:0045664 56 0.011
sequestering of calcium ion GO:0051208 3 0.011
regulation of calcium ion transport GO:0051924 2 0.011
otic vesicle development GO:0071599 42 0.011
sensory organ development GO:0007423 393 0.011
monocyte differentiation GO:0030224 2 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
alcohol biosynthetic process GO:0046165 2 0.011
response to nutrient GO:0007584 3 0.011
axon guidance GO:0007411 86 0.011
negative regulation of blood circulation GO:1903523 2 0.011
somatic muscle development GO:0007525 4 0.011
negative regulation of cellular process GO:0048523 283 0.011
Human Mouse
oxidation reduction process GO:0055114 41 0.011
behavior GO:0007610 74 0.011
regulation of erythrocyte differentiation GO:0045646 2 0.011
response to hypoxia GO:0001666 25 0.011
heart jogging GO:0003146 40 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
actin cytoskeleton organization GO:0030036 63 0.011
Worm
positive regulation of secretion GO:0051047 1 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
regulation of molecular function GO:0065009 70 0.011
neuron projection guidance GO:0097485 86 0.011
anterior posterior pattern specification GO:0009952 152 0.011
intracellular signal transduction GO:0035556 85 0.011
death GO:0016265 121 0.011
Human
fatty acid beta oxidation GO:0006635 1 0.011
muscle tissue development GO:0060537 110 0.011
Mouse
ion transmembrane transport GO:0034220 91 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
Human Mouse
b cell activation GO:0042113 2 0.011
germ line stem cell maintenance GO:0030718 2 0.010
regulation of protein localization to plasma membrane GO:1903076 1 0.010
calcium ion import GO:0070509 4 0.010
cellular biogenic amine metabolic process GO:0006576 2 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
blood vessel development GO:0001568 246 0.010
cellular protein metabolic process GO:0044267 129 0.010
response to wounding GO:0009611 116 0.010
inorganic anion transport GO:0015698 25 0.010
cellular response to organic substance GO:0071310 105 0.010
hemopoiesis GO:0030097 183 0.010
purine ribonucleotide metabolic process GO:0009150 27 0.010

fhl2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
cardiovascular system disease DOID:1287 0 0.057
musculoskeletal system disease DOID:17 0 0.024
myopathy DOID:423 0 0.017
muscular disease DOID:0080000 0 0.017
muscle tissue disease DOID:66 0 0.017
heart disease DOID:114 0 0.012
disease of metabolism DOID:0014667 0 0.011