Danio rerio

0 known processes

fhl2b

four and a half LIM domains 2b

(Aliases: zgc:103466)

fhl2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 353 0.131
cellular component movement GO:0006928 335 0.131
cell part morphogenesis GO:0032990 246 0.097
immune system process GO:0002376 241 0.095
determination of left right symmetry GO:0007368 179 0.095
embryonic organ morphogenesis GO:0048562 274 0.085
locomotion GO:0040011 313 0.084
central nervous system development GO:0007417 387 0.081
larval development GO:0002164 2 0.080
chemosensory behavior GO:0007635 1 0.078
nitrogen compound metabolic process GO:0006807 319 0.076
response to external stimulus GO:0009605 264 0.075
lipid storage GO:0019915 1 0.074
localization of cell GO:0051674 244 0.073
determination of heart left right asymmetry GO:0061371 117 0.066
cell projection organization GO:0030030 284 0.065
cellular component morphogenesis GO:0032989 336 0.064
digestive system development GO:0055123 289 0.064
maintenance of location GO:0051235 4 0.063
cell projection morphogenesis GO:0048858 244 0.062
neuron development GO:0048666 262 0.058
tube morphogenesis GO:0035239 349 0.056
positive regulation of transport GO:0051050 2 0.055
phagocytosis GO:0006909 3 0.054
meiotic nuclear division GO:0007126 4 0.053
regulation of synapse organization GO:0050807 3 0.053
cell morphogenesis GO:0000902 289 0.052
regulation of nitrogen compound metabolic process GO:0051171 251 0.052
determination of bilateral symmetry GO:0009855 204 0.051
heart looping GO:0001947 94 0.050
spermatid development GO:0007286 2 0.050
regulation of cell activation GO:0050865 1 0.049
organic acid metabolic process GO:0006082 31 0.049
digestive tract morphogenesis GO:0048546 231 0.048
nucleobase containing compound metabolic process GO:0006139 274 0.047
guanosine containing compound metabolic process GO:1901068 4 0.047
small molecule metabolic process GO:0044281 77 0.047
response to chemical GO:0042221 320 0.046
mononuclear cell proliferation GO:0032943 1 0.046
organic cyclic compound metabolic process GO:1901360 301 0.046
positive regulation of cell activation GO:0050867 1 0.045
organic cyclic compound biosynthetic process GO:1901362 223 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.044
organelle organization GO:0006996 227 0.043
specification of symmetry GO:0009799 204 0.043
digestive tract development GO:0048565 265 0.043
catechol containing compound metabolic process GO:0009712 2 0.043
oocyte anterior posterior axis specification GO:0007314 4 0.042
cellular macromolecule metabolic process GO:0044260 391 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.042
cell migration GO:0016477 237 0.041
regulation of biological quality GO:0065008 263 0.041
neuron projection morphogenesis GO:0048812 161 0.040
negative regulation of cellular process GO:0048523 283 0.039
striated muscle cell development GO:0055002 108 0.039
heart morphogenesis GO:0003007 156 0.039
regulation of gene expression GO:0010468 265 0.038
regulation of meiotic cell cycle GO:0051445 1 0.038
single organism transport GO:0044765 206 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
cellular biosynthetic process GO:0044249 286 0.037
generation of neurons GO:0048699 385 0.037
transport GO:0006810 220 0.037
regulation of macromolecule metabolic process GO:0060255 317 0.037
regulation of metabolic process GO:0019222 359 0.037
cellular component assembly GO:0022607 170 0.037
embryonic heart tube morphogenesis GO:0003143 108 0.037
cellular amine metabolic process GO:0044106 2 0.036
membrane invagination GO:0010324 1 0.036
regulation of synapse assembly GO:0051963 3 0.036
actin polymerization or depolymerization GO:0008154 2 0.036
immune system development GO:0002520 191 0.036
eye development GO:0001654 277 0.036
sequestering of calcium ion GO:0051208 3 0.035
aging GO:0007568 2 0.035
spermatid differentiation GO:0048515 2 0.035
heterocycle metabolic process GO:0046483 290 0.035
morphogenesis of an epithelium GO:0002009 333 0.034
establishment of localization GO:0051234 244 0.034
heart development GO:0007507 313 0.034
gland development GO:0048732 143 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
gene expression GO:0010467 252 0.034
nuclear import GO:0051170 3 0.034
anterior posterior pattern specification GO:0009952 152 0.033
cellular amino acid metabolic process GO:0006520 7 0.033
response to glucocorticoid GO:0051384 1 0.033
cellular component biogenesis GO:0044085 178 0.032
regulation of sequestering of calcium ion GO:0051282 4 0.032
regulation of cytokine production GO:0001817 3 0.032
regulation of neuronal synaptic plasticity GO:0048168 1 0.032
regulation of cell communication GO:0010646 232 0.032
Zebrafish
phagocytosis engulfment GO:0006911 1 0.032
regulation of multicellular organismal process GO:0051239 277 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.031
synaptic vesicle transport GO:0048489 1 0.030
positive regulation of leukocyte differentiation GO:1902107 1 0.030
single organism metabolic process GO:0044710 217 0.030
negative regulation of synapse assembly GO:0051964 2 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
organic substance biosynthetic process GO:1901576 289 0.030
cognition GO:0050890 1 0.030
intracellular mrna localization GO:0008298 1 0.030
regulation of cellular metabolic process GO:0031323 320 0.030
embryonic organ development GO:0048568 381 0.029
regulation of signaling GO:0023051 235 0.029
Zebrafish
regulation of protein complex assembly GO:0043254 3 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
taxis GO:0042330 109 0.029
small molecule catabolic process GO:0044282 3 0.029
synaptic vesicle localization GO:0097479 1 0.028
single organism localization GO:1902578 225 0.028
protein targeting to nucleus GO:0044744 3 0.028
gtp catabolic process GO:0006184 2 0.028
carboxylic acid metabolic process GO:0019752 22 0.028
positive regulation of biological process GO:0048518 253 0.028
cytokinesis GO:0000910 3 0.028
head development GO:0060322 303 0.027
muscle cell differentiation GO:0042692 139 0.027
alpha amino acid metabolic process GO:1901605 3 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.027
lymphocyte proliferation GO:0046651 1 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
secondary metabolic process GO:0019748 3 0.026
nucleic acid metabolic process GO:0090304 244 0.026
leukocyte proliferation GO:0070661 1 0.026
neuron projection guidance GO:0097485 86 0.026
stem cell maintenance GO:0019827 4 0.026
hematopoietic or lymphoid organ development GO:0048534 191 0.026
adult behavior GO:0030534 2 0.025
mitochondrion organization GO:0007005 4 0.025
multi organism process GO:0051704 134 0.025
cell motility GO:0048870 244 0.025
organelle assembly GO:0070925 110 0.025
brain development GO:0007420 293 0.025
response to drug GO:0042493 3 0.025
cytoskeleton organization GO:0007010 96 0.025
glial cell migration GO:0008347 3 0.025
endosomal transport GO:0016197 2 0.025
melanin metabolic process GO:0006582 2 0.025
carboxylic acid catabolic process GO:0046395 3 0.025
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
amine metabolic process GO:0009308 2 0.024
regulation of primary metabolic process GO:0080090 311 0.024
gtp metabolic process GO:0046039 4 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.023
protein import GO:0017038 3 0.023
axon development GO:0061564 166 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
regulation of multicellular organismal development GO:2000026 223 0.022
embryonic heart tube development GO:0035050 133 0.022
maternal determination of anterior posterior axis embryo GO:0008358 4 0.022
oxoacid metabolic process GO:0043436 31 0.022
muscle structure development GO:0061061 196 0.022
pole plasm assembly GO:0007315 4 0.022
catecholamine metabolic process GO:0006584 2 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
cilium morphogenesis GO:0060271 85 0.021
regulation of cell shape GO:0008360 1 0.021
epithelial tube morphogenesis GO:0060562 148 0.021
response to stress GO:0006950 263 0.021
biosynthetic process GO:0009058 294 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
regulation of reproductive process GO:2000241 4 0.020
regulation of response to stimulus GO:0048583 269 0.020
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.020
rna localization GO:0006403 4 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
positive regulation of cellular process GO:0048522 201 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
ameboidal type cell migration GO:0001667 143 0.020
tissue remodeling GO:0048771 4 0.020
response to biotic stimulus GO:0009607 97 0.019
regulation of protein polymerization GO:0032271 2 0.019
leukocyte mediated cytotoxicity GO:0001909 1 0.019
cilium organization GO:0044782 71 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
negative regulation of protein complex assembly GO:0031333 1 0.019
cellular ketone metabolic process GO:0042180 11 0.019
protein secretion GO:0009306 1 0.019
negative regulation of sequestering of calcium ion GO:0051283 4 0.019
positive regulation of catabolic process GO:0009896 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
retina development in camera type eye GO:0060041 146 0.019
b cell activation GO:0042113 2 0.019
neuron projection development GO:0031175 180 0.019
apical junction assembly GO:0043297 1 0.019
lateral inhibition GO:0046331 1 0.018
single organism organelle organization GO:1902589 199 0.018
cytoplasm organization GO:0007028 4 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
nuclear transport GO:0051169 4 0.018
camera type eye development GO:0043010 222 0.018
pigmentation GO:0043473 85 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
cellular response to external stimulus GO:0071496 2 0.018
positive regulation of secretion GO:0051047 1 0.018
segmentation GO:0035282 97 0.018
cortical actin cytoskeleton organization GO:0030866 1 0.018
axon guidance GO:0007411 86 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
response to ketone GO:1901654 1 0.017
somatic muscle development GO:0007525 4 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of binding GO:0051098 3 0.017
sequestering of metal ion GO:0051238 3 0.017
organelle localization GO:0051640 49 0.017
regulation of cell projection assembly GO:0060491 4 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
posterior lateral line system development GO:0048915 46 0.017
positive regulation of metabolic process GO:0009893 108 0.017
vitamin a metabolic process GO:0006776 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
hemopoiesis GO:0030097 183 0.017
bone remodeling GO:0046849 2 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of transcription dna templated GO:0006355 213 0.017
neurotransmitter secretion GO:0007269 2 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
response to wounding GO:0009611 116 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.016
protein import into nucleus GO:0006606 3 0.016
negative regulation of biological process GO:0048519 304 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
multicellular organism growth GO:0035264 4 0.016
positive regulation of immune effector process GO:0002699 3 0.016
rna metabolic process GO:0016070 219 0.016
catechol containing compound biosynthetic process GO:0009713 2 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
regulation of developmental process GO:0050793 247 0.016
cell substrate adhesion GO:0031589 4 0.016
membrane fusion GO:0061025 2 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
protein polymerization GO:0051258 4 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
intracellular signal transduction GO:0035556 85 0.016
Zebrafish
mesenchyme development GO:0060485 127 0.016
signal transduction GO:0007165 455 0.016
Zebrafish
regulation of rna metabolic process GO:0051252 224 0.016
sensory organ morphogenesis GO:0090596 200 0.016
axonogenesis GO:0007409 152 0.015
regulation of signal transduction GO:0009966 225 0.015
Zebrafish
transcription dna templated GO:0006351 181 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
regionalization GO:0003002 274 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
meiotic cell cycle process GO:1903046 3 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
positive regulation of cell cycle GO:0045787 3 0.015
dopamine metabolic process GO:0042417 2 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
actin filament polymerization GO:0030041 2 0.015
cell fate commitment GO:0045165 99 0.015
cortical cytoskeleton organization GO:0030865 1 0.015
actin cytoskeleton organization GO:0030036 63 0.015
organophosphate biosynthetic process GO:0090407 23 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
striated muscle tissue development GO:0014706 110 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
regulation of biosynthetic process GO:0009889 250 0.014
adherens junction organization GO:0034332 4 0.014
atp catabolic process GO:0006200 4 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
fertilization GO:0009566 3 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
b cell differentiation GO:0030183 1 0.014
dopamine biosynthetic process GO:0042416 2 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
response to uv GO:0009411 3 0.014
regulation of neurogenesis GO:0050767 87 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.014
response to nutrient GO:0007584 3 0.014
entrainment of circadian clock by photoperiod GO:0043153 1 0.014
cellular aldehyde metabolic process GO:0006081 4 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
establishment of organelle localization GO:0051656 45 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
response to organic substance GO:0010033 153 0.013
organic acid catabolic process GO:0016054 3 0.013
convergent extension involved in gastrulation GO:0060027 71 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of apoptotic process GO:0042981 98 0.013
regulation of inflammatory response GO:0050727 2 0.013
alcohol biosynthetic process GO:0046165 2 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
circulatory system process GO:0003013 87 0.013
Zebrafish
regulation of skeletal muscle tissue development GO:0048641 4 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
regulation of skeletal muscle fiber development GO:0048742 2 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
lamellipodium organization GO:0097581 1 0.013
regulation of cell development GO:0060284 100 0.013
rna biosynthetic process GO:0032774 181 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
response to corticosteroid GO:0031960 1 0.013
sensory organ development GO:0007423 393 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
positive regulation of cytokine production GO:0001819 2 0.013
multicellular organismal signaling GO:0035637 22 0.013
interspecies interaction between organisms GO:0044419 4 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
cell cell signaling GO:0007267 52 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regulation of protein binding GO:0043393 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
regulation of gtpase activity GO:0043087 2 0.012
nucleic acid templated transcription GO:0097659 181 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
single organism membrane fusion GO:0044801 2 0.012
response to vitamin GO:0033273 3 0.012
chemotaxis GO:0006935 104 0.012
protein localization to nucleus GO:0034504 3 0.012
organonitrogen compound biosynthetic process GO:1901566 47 0.012
regulation of transporter activity GO:0032409 2 0.012
locomotor rhythm GO:0045475 3 0.012
response to lipid GO:0033993 60 0.012
regulation of dendrite development GO:0050773 3 0.012
myotube differentiation GO:0014902 45 0.012
cellular component disassembly GO:0022411 1 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
programmed cell death GO:0012501 119 0.012
peripheral nervous system development GO:0007422 55 0.012
peptide metabolic process GO:0006518 1 0.012
water homeostasis GO:0030104 4 0.012
mesodermal cell migration GO:0008078 12 0.012
heart process GO:0003015 71 0.012
Zebrafish
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.012
negative regulation of defense response GO:0031348 2 0.012
cell proliferation GO:0008283 80 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
protein metabolic process GO:0019538 183 0.012
macromolecular complex disassembly GO:0032984 1 0.012
neuronal action potential GO:0019228 18 0.012
neurotransmitter transport GO:0006836 2 0.012
cellular lipid catabolic process GO:0044242 3 0.011
regulation of filopodium assembly GO:0051489 2 0.011
response to other organism GO:0051707 97 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
response to alkaloid GO:0043279 2 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
cellular localization GO:0051641 97 0.011
regulation of mrna processing GO:0050684 3 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
positive regulation of gliogenesis GO:0014015 2 0.011
cell projection assembly GO:0030031 64 0.011
chordate embryonic development GO:0043009 271 0.011
ventricular cardiac muscle cell development GO:0055015 5 0.011
wound healing GO:0042060 90 0.011
single fertilization GO:0007338 3 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regulation of jak stat cascade GO:0046425 3 0.011
negative regulation of gene expression GO:0010629 65 0.011
fatty acid catabolic process GO:0009062 1 0.011
response to hydrogen peroxide GO:0042542 3 0.011
protein localization to plasma membrane GO:0072659 1 0.011
developmental growth GO:0048589 166 0.011
negative regulation of cytokine production GO:0001818 1 0.011
blood circulation GO:0008015 87 0.011
Zebrafish
cellular response to extracellular stimulus GO:0031668 2 0.011
cellular response to nutrient levels GO:0031669 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
muscle organ development GO:0007517 101 0.011
female meiotic division GO:0007143 2 0.011
transmission of nerve impulse GO:0019226 19 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
positive regulation of inflammatory response GO:0050729 1 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
embryonic skeletal joint development GO:0072498 3 0.011
macromolecule modification GO:0043412 111 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
striated muscle cell differentiation GO:0051146 129 0.011
antimicrobial humoral response GO:0019730 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
myofibril assembly GO:0030239 48 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
lymphocyte activation GO:0046649 10 0.010
embryonic digestive tract development GO:0048566 4 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.010
lymphocyte homeostasis GO:0002260 1 0.010
positive regulation of multi organism process GO:0043902 3 0.010
single organism biosynthetic process GO:0044711 71 0.010
meiotic chromosome segregation GO:0045132 3 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
homeostatic process GO:0042592 142 0.010
somitogenesis GO:0001756 87 0.010
mechanosensory lateral line system development GO:0048881 49 0.010

fhl2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.028
cardiovascular system disease DOID:1287 0 0.018
heart disease DOID:114 0 0.018
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
myopathy DOID:423 0 0.011