Danio rerio

15 known processes

hrh2

histamine receptor H2

hrh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glucose import GO:0046323 2 0.118
vasculature development GO:0001944 278 0.107
regulation of reactive oxygen species metabolic process GO:2000377 2 0.075
cognition GO:0050890 1 0.067
liver development GO:0001889 96 0.064
transmembrane transport GO:0055085 120 0.062
g protein coupled receptor signaling pathway GO:0007186 74 0.059
regulation of synaptic plasticity GO:0048167 1 0.057
cellular biosynthetic process GO:0044249 286 0.050
single organism transport GO:0044765 206 0.048
larval development GO:0002164 2 0.048
reactive oxygen species metabolic process GO:0072593 6 0.047
autophagy GO:0006914 4 0.045
transport GO:0006810 220 0.043
cell surface receptor signaling pathway GO:0007166 325 0.041
regulation of tube size GO:0035150 2 0.040
cellular response to external stimulus GO:0071496 2 0.039
carbohydrate transport GO:0008643 13 0.039
regulation of blood vessel size GO:0050880 2 0.038
reactive nitrogen species metabolic process GO:2001057 0 0.035
neuron neuron synaptic transmission GO:0007270 1 0.034
positive regulation of blood circulation GO:1903524 2 0.031
positive regulation of transport GO:0051050 2 0.030
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
system process GO:0003008 185 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
signal transduction GO:0007165 455 0.028
cellular response to lipopolysaccharide GO:0071222 3 0.028
positive regulation of cytokine production GO:0001819 2 0.027
establishment of localization GO:0051234 244 0.027
cellular response to nutrient levels GO:0031669 2 0.026
cellular amine metabolic process GO:0044106 2 0.026
nitric oxide biosynthetic process GO:0006809 2 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
cellular response to starvation GO:0009267 1 0.025
organelle fusion GO:0048284 3 0.025
aging GO:0007568 2 0.025
blood circulation GO:0008015 87 0.025
cellular amino acid metabolic process GO:0006520 7 0.024
regulation of cytokine production GO:0001817 3 0.024
positive regulation of secretion by cell GO:1903532 1 0.024
cellular response to biotic stimulus GO:0071216 3 0.024
stem cell proliferation GO:0072089 4 0.024
cellular component biogenesis GO:0044085 178 0.024
positive regulation of cell cycle GO:0045787 3 0.023
circulatory system process GO:0003013 87 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
gland development GO:0048732 143 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
cellular protein catabolic process GO:0044257 4 0.022
epithelial cell differentiation GO:0030855 116 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
meiotic cell cycle process GO:1903046 3 0.021
single fertilization GO:0007338 3 0.021
multicellular organism growth GO:0035264 4 0.021
cytokinesis GO:0000910 3 0.021
nitric oxide metabolic process GO:0046209 2 0.021
i kappab kinase nf kappab signaling GO:0007249 4 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
organic substance biosynthetic process GO:1901576 289 0.021
single organism localization GO:1902578 225 0.021
negative regulation of biological process GO:0048519 304 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
chemosensory behavior GO:0007635 1 0.020
regulation of apoptotic process GO:0042981 98 0.020
response to hexose GO:0009746 3 0.020
reactive oxygen species biosynthetic process GO:1903409 1 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.020
regulation of protein transport GO:0051223 3 0.020
fertilization GO:0009566 3 0.020
cerebellum vasculature development GO:0061300 1 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
hepaticobiliary system development GO:0061008 98 0.019
negative regulation of cellular process GO:0048523 283 0.019
response to glucose GO:0009749 3 0.019
regulation of binding GO:0051098 3 0.019
sensory organ development GO:0007423 393 0.019
single organism metabolic process GO:0044710 217 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of signal transduction GO:0009966 225 0.019
regulation of biological quality GO:0065008 263 0.019
regulation of protein complex assembly GO:0043254 3 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
negative regulation of catabolic process GO:0009895 3 0.018
cell death GO:0008219 121 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
response to chemical GO:0042221 320 0.018
cellular component morphogenesis GO:0032989 336 0.018
chordate embryonic development GO:0043009 271 0.018
response to monosaccharide GO:0034284 3 0.018
gtp catabolic process GO:0006184 2 0.018
membrane fusion GO:0061025 2 0.018
compound eye development GO:0048749 2 0.017
response to external biotic stimulus GO:0043207 97 0.017
regulation of metal ion transport GO:0010959 4 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
amine metabolic process GO:0009308 2 0.017
mitochondrion organization GO:0007005 4 0.017
blood vessel development GO:0001568 246 0.017
head development GO:0060322 303 0.017
adult behavior GO:0030534 2 0.017
synaptic transmission GO:0007268 35 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
cell part morphogenesis GO:0032990 246 0.017
response to carbohydrate GO:0009743 3 0.017
cellular ketone metabolic process GO:0042180 11 0.017
striated muscle cell differentiation GO:0051146 129 0.017
maintenance of location GO:0051235 4 0.017
response to biotic stimulus GO:0009607 97 0.017
regulation of inflammatory response GO:0050727 2 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
regulation of synapse assembly GO:0051963 3 0.016
biosynthetic process GO:0009058 294 0.016
immune system process GO:0002376 241 0.016
hemopoiesis GO:0030097 183 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
negative regulation of metabolic process GO:0009892 86 0.016
glucose homeostasis GO:0042593 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
neurotransmitter transport GO:0006836 2 0.016
regulation of synapse organization GO:0050807 3 0.016
nuclear import GO:0051170 3 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
response to other organism GO:0051707 97 0.016
regulation of cell communication GO:0010646 232 0.016
positive regulation of secretion GO:0051047 1 0.016
meiotic nuclear division GO:0007126 4 0.016
regulation of protein catabolic process GO:0042176 1 0.015
heart process GO:0003015 71 0.015
retina development in camera type eye GO:0060041 146 0.015
response to external stimulus GO:0009605 264 0.015
cellular component disassembly GO:0022411 1 0.015
positive regulation of cell activation GO:0050867 1 0.015
exocytosis GO:0006887 1 0.015
single organism membrane fusion GO:0044801 2 0.015
programmed cell death GO:0012501 119 0.015
rna localization GO:0006403 4 0.015
positive regulation of catabolic process GO:0009896 4 0.015
ion transmembrane transport GO:0034220 91 0.015
eye development GO:0001654 277 0.015
cellular component assembly GO:0022607 170 0.015
positive regulation of wound healing GO:0090303 1 0.015
protein localization to nucleus GO:0034504 3 0.015
neurotransmitter secretion GO:0007269 2 0.015
phagocytosis GO:0006909 3 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
protein secretion GO:0009306 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.014
nuclear transport GO:0051169 4 0.014
response to abiotic stimulus GO:0009628 122 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
peptidyl serine modification GO:0018209 2 0.014
anion transport GO:0006820 38 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
embryonic organ development GO:0048568 381 0.014
striated muscle cell development GO:0055002 108 0.014
gtp metabolic process GO:0046039 4 0.014
protein heterooligomerization GO:0051291 1 0.014
oxoacid metabolic process GO:0043436 31 0.014
organic acid catabolic process GO:0016054 3 0.014
membrane invagination GO:0010324 1 0.014
adherens junction organization GO:0034332 4 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
stem cell maintenance GO:0019827 4 0.014
energy reserve metabolic process GO:0006112 2 0.014
single organism nuclear import GO:1902593 3 0.014
stem cell division GO:0017145 1 0.014
negative regulation of apoptotic process GO:0043066 55 0.014
cell morphogenesis GO:0000902 289 0.014
response to radiation GO:0009314 51 0.014
protein targeting to nucleus GO:0044744 3 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
cytoplasm organization GO:0007028 4 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
neuroblast proliferation GO:0007405 2 0.014
developmental programmed cell death GO:0010623 4 0.014
regulation of system process GO:0044057 40 0.014
muscle structure development GO:0061061 196 0.014
translational initiation GO:0006413 3 0.014
positive regulation of immune effector process GO:0002699 3 0.014
death GO:0016265 121 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
regulation of blood pressure GO:0008217 1 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
protein acetylation GO:0006473 2 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
nuclear migration GO:0007097 3 0.013
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
carboxylic acid catabolic process GO:0046395 3 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
regulation of wound healing GO:0061041 2 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
regulation of cell projection assembly GO:0060491 4 0.013
intracellular mrna localization GO:0008298 1 0.012
angiogenesis GO:0001525 158 0.012
response to light stimulus GO:0009416 46 0.012
blood vessel morphogenesis GO:0048514 216 0.012
spermatid differentiation GO:0048515 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
lipid storage GO:0019915 1 0.012
protein dephosphorylation GO:0006470 3 0.012
interspecies interaction between organisms GO:0044419 4 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
spermatid development GO:0007286 2 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
regulation of dendrite development GO:0050773 3 0.012
ion transport GO:0006811 114 0.012
phagocytosis engulfment GO:0006911 1 0.012
regulation of gene expression GO:0010468 265 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cell projection morphogenesis GO:0048858 244 0.012
regionalization GO:0003002 274 0.012
regulation of signaling GO:0023051 235 0.012
regulation of calcium ion transport GO:0051924 2 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
apoptotic process GO:0006915 116 0.011
neurological system process GO:0050877 62 0.011
neuron projection development GO:0031175 180 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
centrosome organization GO:0051297 1 0.011
atp catabolic process GO:0006200 4 0.011
response to stress GO:0006950 263 0.011
synaptic vesicle localization GO:0097479 1 0.011
protein import GO:0017038 3 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
negative regulation of defense response GO:0031348 2 0.011
antimicrobial humoral response GO:0019730 2 0.011
protein metabolic process GO:0019538 183 0.011
protein import into nucleus GO:0006606 3 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
regulation of autophagy GO:0010506 3 0.011
female sex differentiation GO:0046660 4 0.011
hormone secretion GO:0046879 2 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
inorganic cation transmembrane transport GO:0098662 50 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
endosomal transport GO:0016197 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
muscle cell differentiation GO:0042692 139 0.011
germ line stem cell maintenance GO:0030718 2 0.011
endocrine process GO:0050886 2 0.011
behavior GO:0007610 74 0.011
single organism biosynthetic process GO:0044711 71 0.011
regulation of dna replication GO:0006275 3 0.011
central nervous system development GO:0007417 387 0.011
protein localization to plasma membrane GO:0072659 1 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
small molecule catabolic process GO:0044282 3 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
positive regulation of cell division GO:0051781 2 0.010
response to amphetamine GO:0001975 1 0.010
negative regulation of reproductive process GO:2000242 3 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
cellular response to organic substance GO:0071310 105 0.010
transcription dna templated GO:0006351 181 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
visual behavior GO:0007632 10 0.010
positive regulation of camp biosynthetic process GO:0030819 2 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
positive regulation of histone modification GO:0031058 1 0.010
b cell activation GO:0042113 2 0.010
regulation of multicellular organismal metabolic process GO:0044246 2 0.010
positive regulation of translation GO:0045727 1 0.010
leukocyte proliferation GO:0070661 1 0.010
multicellular organismal signaling GO:0035637 22 0.010
cell migration GO:0016477 237 0.010
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
tissue remodeling GO:0048771 4 0.010
amino acid transport GO:0006865 2 0.010
regulation of muscle contraction GO:0006937 3 0.010
golgi vesicle transport GO:0048193 3 0.010
multicellular organismal response to stress GO:0033555 2 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
regulation of neurotransmitter secretion GO:0046928 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
epithelial tube morphogenesis GO:0060562 148 0.010

hrh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
nervous system disease DOID:863 0 0.032
musculoskeletal system disease DOID:17 0 0.015
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010
immune system disease DOID:2914 0 0.010