Danio rerio

0 known processes

glud1a

glutamate dehydrogenase 1a

(Aliases: wu:fc66a10,cb622,wu:fc33g09,zgc:77186,glud1)

glud1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to external stimulus GO:0009605 264 0.843
alpha amino acid metabolic process GO:1901605 3 0.578
Human Mouse Fly
response to biotic stimulus GO:0009607 97 0.449
response to chemical GO:0042221 320 0.421
response to other organism GO:0051707 97 0.360
locomotion GO:0040011 313 0.335
multi organism process GO:0051704 134 0.310
response to stress GO:0006950 263 0.297
axonogenesis GO:0007409 152 0.272
generation of neurons GO:0048699 385 0.236
single organism metabolic process GO:0044710 217 0.200
Human Mouse Fly
response to external biotic stimulus GO:0043207 97 0.193
embryo development ending in birth or egg hatching GO:0009792 271 0.172
cell part morphogenesis GO:0032990 246 0.166
hemopoiesis GO:0030097 183 0.158
immune system development GO:0002520 191 0.151
regulation of metabolic process GO:0019222 359 0.151
neuron projection morphogenesis GO:0048812 161 0.149
response to nutrient GO:0007584 3 0.144
organic acid metabolic process GO:0006082 31 0.137
Human Mouse Fly
cellular component movement GO:0006928 335 0.128
regionalization GO:0003002 274 0.121
regulation of biological quality GO:0065008 263 0.120
Human Mouse
cell projection organization GO:0030030 284 0.119
cell morphogenesis involved in differentiation GO:0000904 195 0.117
immune system process GO:0002376 241 0.115
localization of cell GO:0051674 244 0.114
single organism transport GO:0044765 206 0.114
Human Mouse
glucose homeostasis GO:0042593 1 0.101
regulation of gene expression GO:0010468 265 0.098
cellular amide metabolic process GO:0043603 4 0.097
outflow tract morphogenesis GO:0003151 1 0.095
cellular response to organic substance GO:0071310 105 0.093
heart development GO:0007507 313 0.093
system process GO:0003008 185 0.091
organonitrogen compound metabolic process GO:1901564 74 0.091
Human Mouse Fly
negative regulation of biological process GO:0048519 304 0.090
aging GO:0007568 2 0.087
cellular amino acid metabolic process GO:0006520 7 0.087
Human Mouse Fly
response to monosaccharide GO:0034284 3 0.087
cell projection morphogenesis GO:0048858 244 0.085
establishment of localization GO:0051234 244 0.082
Human Mouse
cellular response to lipid GO:0071396 39 0.082
response to organic substance GO:0010033 153 0.082
response to endogenous stimulus GO:0009719 83 0.080
oxoacid metabolic process GO:0043436 31 0.077
Human Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.077
neuron projection guidance GO:0097485 86 0.077
response to abiotic stimulus GO:0009628 122 0.075
protein metabolic process GO:0019538 183 0.072
response to carbohydrate GO:0009743 3 0.072
regulation of signaling GO:0023051 235 0.072
Human Mouse
cellular response to chemical stimulus GO:0070887 157 0.071
central nervous system development GO:0007417 387 0.069
Human
single organism organelle organization GO:1902589 199 0.068
response to nutrient levels GO:0031667 10 0.068
organic cyclic compound metabolic process GO:1901360 301 0.068
Fly
cell morphogenesis GO:0000902 289 0.067
carbohydrate homeostasis GO:0033500 1 0.067
cellular response to biotic stimulus GO:0071216 3 0.064
establishment of localization in cell GO:0051649 77 0.063
Human Mouse
cellular component morphogenesis GO:0032989 336 0.063
regulation of nervous system development GO:0051960 90 0.063
lipid storage GO:0019915 1 0.062
positive regulation of cell differentiation GO:0045597 30 0.060
axon development GO:0061564 166 0.060
mesenchymal cell differentiation GO:0048762 87 0.059
carboxylic acid metabolic process GO:0019752 22 0.058
Human Mouse Fly
stem cell division GO:0017145 1 0.057
cell motility GO:0048870 244 0.056
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 6 0.056
proteolysis GO:0006508 38 0.055
extrinsic apoptotic signaling pathway GO:0097191 3 0.055
regulation of hormone secretion GO:0046883 2 0.055
Human Mouse
stem cell development GO:0048864 82 0.054
growth GO:0040007 174 0.054
Worm
meiotic nuclear division GO:0007126 4 0.054
gene expression GO:0010467 252 0.053
circulatory system process GO:0003013 87 0.053
hematopoietic or lymphoid organ development GO:0048534 191 0.052
cellular protein catabolic process GO:0044257 4 0.050
mesenchyme development GO:0060485 127 0.050
cell proliferation GO:0008283 80 0.049
intestinal cholesterol absorption GO:0030299 2 0.049
negative regulation of stem cell differentiation GO:2000737 2 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
epithelial cell differentiation GO:0030855 116 0.047
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.047
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.047
nitrogen compound metabolic process GO:0006807 319 0.046
Human Mouse Fly
regulation of stem cell differentiation GO:2000736 4 0.046
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.046
cellular response to organic cyclic compound GO:0071407 38 0.046
cellular response to external stimulus GO:0071496 2 0.045
organelle organization GO:0006996 227 0.045
cation homeostasis GO:0055080 33 0.044
response to hexose GO:0009746 3 0.043
transport GO:0006810 220 0.042
Human Mouse
digestive system development GO:0055123 289 0.042
regulation of dendrite development GO:0050773 3 0.042
cytoskeleton dependent cytokinesis GO:0061640 3 0.042
taxis GO:0042330 109 0.041
neuron differentiation GO:0030182 353 0.041
wound healing GO:0042060 90 0.041
digestive tract morphogenesis GO:0048546 231 0.040
cellular modified amino acid metabolic process GO:0006575 3 0.040
cellular amino acid biosynthetic process GO:0008652 2 0.040
Human
response to inorganic substance GO:0010035 38 0.040
response to alkaloid GO:0043279 2 0.039
regulation of inflammatory response GO:0050727 2 0.038
digestive tract development GO:0048565 265 0.038
maternal determination of anterior posterior axis embryo GO:0008358 4 0.038
positive regulation of nervous system development GO:0051962 25 0.038
enzyme linked receptor protein signaling pathway GO:0007167 106 0.037
sensory perception of chemical stimulus GO:0007606 3 0.037
peptide transport GO:0015833 1 0.037
Human Mouse
dicarboxylic acid metabolic process GO:0043648 1 0.037
Human Fly
cytoskeleton organization GO:0007010 96 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
positive regulation of biological process GO:0048518 253 0.035
Human Mouse
membrane organization GO:0061024 21 0.035
gastrulation with mouth forming second GO:0001702 44 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
stem cell maintenance GO:0019827 4 0.035
ear development GO:0043583 127 0.034
negative regulation of myeloid cell differentiation GO:0045638 1 0.034
pancreas development GO:0031016 84 0.034
blood circulation GO:0008015 87 0.034
homeostatic process GO:0042592 142 0.034
defense response GO:0006952 47 0.033
response to bacterium GO:0009617 58 0.033
cell growth GO:0016049 57 0.033
neurological system process GO:0050877 62 0.033
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.033
regulation of cellular component organization GO:0051128 86 0.033
negative regulation of mapk cascade GO:0043409 4 0.033
cellular response to nutrient levels GO:0031669 2 0.032
chemotaxis GO:0006935 104 0.032
regulation of signal transduction GO:0009966 225 0.032
developmental growth GO:0048589 166 0.031
positive regulation of cell development GO:0010720 25 0.031
single organism cell adhesion GO:0098602 29 0.031
larval development GO:0002164 2 0.031
positive regulation of cell cycle GO:0045787 3 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.030
hormone transport GO:0009914 2 0.030
Human Mouse
primary neural tube formation GO:0014020 1 0.030
hepaticobiliary system development GO:0061008 98 0.030
phagocytosis GO:0006909 3 0.030
cellular response to endogenous stimulus GO:0071495 68 0.030
regulation of cytokine production GO:0001817 3 0.029
small molecule metabolic process GO:0044281 77 0.029
Human Mouse Fly
response to corticosteroid GO:0031960 1 0.029
response to virus GO:0009615 21 0.028
response to growth factor GO:0070848 39 0.028
negative regulation of cellular process GO:0048523 283 0.028
gland development GO:0048732 143 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
cellular component assembly GO:0022607 170 0.027
single organism localization GO:1902578 225 0.027
Human Mouse
transition metal ion transport GO:0000041 6 0.027
response to alcohol GO:0097305 14 0.027
signal transduction GO:0007165 455 0.027
cytokinesis GO:0000910 3 0.027
positive regulation of leukocyte differentiation GO:1902107 1 0.027
regulation of metal ion transport GO:0010959 4 0.026
peptide metabolic process GO:0006518 1 0.026
cilium morphogenesis GO:0060271 85 0.026
cellular response to estrogen stimulus GO:0071391 24 0.026
regulation of neuron differentiation GO:0045664 56 0.026
negative regulation of response to stimulus GO:0048585 104 0.026
regulation of localization GO:0032879 104 0.026
Human Mouse
plasma membrane repair GO:0001778 2 0.025
regulation of cell differentiation GO:0045595 142 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.025
tube morphogenesis GO:0035239 349 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
chordate embryonic development GO:0043009 271 0.025
cellular response to steroid hormone stimulus GO:0071383 31 0.025
negative regulation of cytokine production GO:0001818 1 0.024
dorsal ventral pattern formation GO:0009953 125 0.024
regulation of response to stimulus GO:0048583 269 0.024
positive regulation of transport GO:0051050 2 0.024
Human Mouse
multicellular organism reproduction GO:0032504 35 0.024
maintenance of location GO:0051235 4 0.024
cellular response to lipopolysaccharide GO:0071222 3 0.024
regulation of response to stress GO:0080134 36 0.024
hepatocyte proliferation GO:0072574 2 0.023
negative regulation of epithelial cell proliferation GO:0050680 1 0.023
regulation of epithelial cell proliferation GO:0050678 3 0.023
multicellular organism growth GO:0035264 4 0.023
neuron projection development GO:0031175 180 0.023
macromolecule localization GO:0033036 54 0.023
erk1 and erk2 cascade GO:0070371 4 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.023
Fly
renal system vasculature development GO:0061437 2 0.023
oxidation reduction process GO:0055114 41 0.023
Human Mouse Fly
tissue regeneration GO:0042246 74 0.023
multicellular organismal reproductive process GO:0048609 35 0.022
cellular response to growth factor stimulus GO:0071363 39 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
leukocyte differentiation GO:0002521 25 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
neuron development GO:0048666 262 0.021
reproductive process GO:0022414 40 0.021
intestinal absorption GO:0050892 2 0.021
gliogenesis GO:0042063 45 0.021
positive regulation of translation GO:0045727 1 0.021
cell division GO:0051301 20 0.021
cellular response to xenobiotic stimulus GO:0071466 35 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.021
rna localization GO:0006403 4 0.021
response to wounding GO:0009611 116 0.021
reflex GO:0060004 2 0.020
biosynthetic process GO:0009058 294 0.020
Human
regulation of blood vessel size GO:0050880 2 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
response to amino acid GO:0043200 2 0.020
head development GO:0060322 303 0.020
Human
regulation of macromolecule metabolic process GO:0060255 317 0.020
embryonic heart tube development GO:0035050 133 0.020
establishment of blood brain barrier GO:0060856 2 0.020
regulation of response to external stimulus GO:0032101 31 0.019
protein stabilization GO:0050821 2 0.019
response to radiation GO:0009314 51 0.019
immunoglobulin production GO:0002377 1 0.019
cellular homeostasis GO:0019725 26 0.019
epidermis development GO:0008544 48 0.019
cell cell signaling GO:0007267 52 0.019
Human Mouse
stem cell differentiation GO:0048863 117 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
chemical homeostasis GO:0048878 49 0.018
response to organic cyclic compound GO:0014070 51 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
nuclear import GO:0051170 3 0.018
positive regulation of neurogenesis GO:0050769 24 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
regulation of tube size GO:0035150 2 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
rna metabolic process GO:0016070 219 0.017
pyruvate metabolic process GO:0006090 1 0.017
response to nicotine GO:0035094 2 0.017
germ cell development GO:0007281 22 0.017
regulation of primary metabolic process GO:0080090 311 0.017
heart morphogenesis GO:0003007 156 0.017
protein localization to plasma membrane GO:0072659 1 0.017
swim bladder development GO:0048794 19 0.017
regulation of cell proliferation GO:0042127 37 0.017
response to oxygen containing compound GO:1901700 55 0.016
cation transmembrane transport GO:0098655 65 0.016
vasculature development GO:0001944 278 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
alternative mrna splicing via spliceosome GO:0000380 1 0.016
stem cell proliferation GO:0072089 4 0.016
positive regulation of developmental process GO:0051094 50 0.016
amine metabolic process GO:0009308 2 0.016
rna biosynthetic process GO:0032774 181 0.016
positive regulation of cellular process GO:0048522 201 0.016
Human Mouse
regulation of dendrite morphogenesis GO:0048814 3 0.016
reproduction GO:0000003 40 0.016
Worm
defense response to other organism GO:0098542 33 0.016
cellular aldehyde metabolic process GO:0006081 4 0.016
behavior GO:0007610 74 0.016
tissue homeostasis GO:0001894 25 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
anterior posterior pattern specification GO:0009952 152 0.015
intracellular signal transduction GO:0035556 85 0.015
skeletal system development GO:0001501 181 0.015
single organismal cell cell adhesion GO:0016337 29 0.015
response to food GO:0032094 1 0.015
cell migration GO:0016477 237 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
multicellular organismal water homeostasis GO:0050891 1 0.015
peptidyl serine modification GO:0018209 2 0.015
cell fate commitment GO:0045165 99 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
cartilage development GO:0051216 96 0.015
regulation of protein metabolic process GO:0051246 56 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
cell substrate junction assembly GO:0007044 2 0.015
convergent extension involved in gastrulation GO:0060027 71 0.014
negative regulation of defense response GO:0031348 2 0.014
nuclear export GO:0051168 1 0.014
response to glucose GO:0009749 3 0.014
transmembrane transport GO:0055085 120 0.014
response to glucocorticoid GO:0051384 1 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
protein heterooligomerization GO:0051291 1 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
regulation of growth GO:0040008 42 0.014
organic substance biosynthetic process GO:1901576 289 0.014
Human
negative regulation of signaling GO:0023057 96 0.014
blood vessel development GO:0001568 246 0.014
autophagy GO:0006914 4 0.014
blood vessel morphogenesis GO:0048514 216 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
negative regulation of leukocyte differentiation GO:1902106 1 0.013
organic substance transport GO:0071702 58 0.013
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.013
Fly
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
positive regulation of catabolic process GO:0009896 4 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of binding GO:0051098 3 0.013
regulation of cell development GO:0060284 100 0.013
brain development GO:0007420 293 0.013
Human
regulation of synapse assembly GO:0051963 3 0.013
intracellular mrna localization GO:0008298 1 0.013
cellular amine metabolic process GO:0044106 2 0.013
regeneration GO:0031099 91 0.013
single organism reproductive process GO:0044702 40 0.013
regulation of locomotion GO:0040012 55 0.013
response to lipid GO:0033993 60 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
striated muscle tissue development GO:0014706 110 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
regulation of peptidase activity GO:0052547 23 0.012
renal system process GO:0003014 14 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
regulation of cell activation GO:0050865 1 0.012
myeloid leukocyte differentiation GO:0002573 15 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
female gamete generation GO:0007292 14 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
signal transduction by phosphorylation GO:0023014 18 0.012
heart contraction GO:0060047 71 0.012
regulation of epithelial to mesenchymal transition GO:0010717 3 0.012
regulation of cell motility GO:2000145 46 0.012
regulation of neurogenesis GO:0050767 87 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
optic placode formation involved in camera type eye formation GO:0046619 3 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
fin regeneration GO:0031101 51 0.011
protein targeting to nucleus GO:0044744 3 0.011
response to fungus GO:0009620 25 0.011
response to drug GO:0042493 3 0.011
regulation of organ growth GO:0046620 3 0.011
convergent extension involved in organogenesis GO:0060029 10 0.011
apoptotic process GO:0006915 116 0.011
germ line stem cell maintenance GO:0030718 2 0.011
gastrulation GO:0007369 208 0.011
pole plasm assembly GO:0007315 4 0.011
camera type eye morphogenesis GO:0048593 108 0.011
nephron tubule epithelial cell differentiation GO:0072160 1 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
positive regulation of gliogenesis GO:0014015 2 0.011
metal ion transport GO:0030001 58 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
ion transport GO:0006811 114 0.011
liver development GO:0001889 96 0.011
neurotransmitter transport GO:0006836 2 0.010
negative regulation of kinase activity GO:0033673 4 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
mitotic cell cycle process GO:1903047 48 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
positive regulation of secretion GO:0051047 1 0.010
Human Mouse
lateral inhibition GO:0046331 1 0.010
central nervous system neuron axonogenesis GO:0021955 18 0.010
nucleobase containing compound metabolic process GO:0006139 274 0.010
Fly
water homeostasis GO:0030104 4 0.010
vesicle mediated transport GO:0016192 22 0.010
interaction with host GO:0051701 4 0.010
establishment of cell polarity GO:0030010 18 0.010
actin mediated cell contraction GO:0070252 1 0.010
positive regulation of gene expression GO:0010628 71 0.010
response to extracellular stimulus GO:0009991 10 0.010
innate immune response GO:0045087 13 0.010
positive regulation of multi organism process GO:0043902 3 0.010
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.010

glud1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
disease of metabolism DOID:0014667 0 0.051
Human
inherited metabolic disorder DOID:655 0 0.051
Human
integumentary system disease DOID:16 0 0.022
nervous system disease DOID:863 0 0.014
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
cardiovascular system disease DOID:1287 0 0.011