Danio rerio

33 known processes

lpar1

lysophosphatidic acid receptor 1

(Aliases: MGC113901,si:dz46m7.1,edg2,zgc:92157,si:dz22b13.1)

lpar1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive system development GO:0055123 289 0.845
divalent inorganic cation homeostasis GO:0072507 22 0.819
Rat
digestive tract development GO:0048565 265 0.804
tube morphogenesis GO:0035239 349 0.758
embryonic organ development GO:0048568 381 0.597
signal transduction GO:0007165 455 0.572
negative regulation of ras protein signal transduction GO:0046580 1 0.503
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.495
gastrulation GO:0007369 208 0.489
ameboidal type cell migration GO:0001667 143 0.486
determination of left right symmetry GO:0007368 179 0.484
morphogenesis of an epithelium GO:0002009 333 0.463
locomotion GO:0040011 313 0.455
Rat
regulation of biological quality GO:0065008 263 0.449
Rat
blood vessel development GO:0001568 246 0.422
regulation of response to stimulus GO:0048583 269 0.403
Human Zebrafish Mouse Rat
blood vessel morphogenesis GO:0048514 216 0.314
eye development GO:0001654 277 0.308
determination of bilateral symmetry GO:0009855 204 0.302
homeostatic process GO:0042592 142 0.301
Rat
localization of cell GO:0051674 244 0.289
Rat
establishment of localization GO:0051234 244 0.280
calcium ion homeostasis GO:0055074 19 0.270
Rat
cellular component assembly GO:0022607 170 0.260
Mouse
cellular extravasation GO:0045123 1 0.251
cellular component movement GO:0006928 335 0.247
Rat
sprouting angiogenesis GO:0002040 53 0.229
vasculature development GO:0001944 278 0.223
response to vitamin GO:0033273 3 0.210
digestive tract morphogenesis GO:0048546 231 0.209
sensory organ development GO:0007423 393 0.201
maintenance of location GO:0051235 4 0.198
morphogenesis of an epithelial sheet GO:0002011 49 0.197
pericardium morphogenesis GO:0003344 1 0.188
cell migration involved in gastrulation GO:0042074 79 0.185
heart development GO:0007507 313 0.183
nucleic acid metabolic process GO:0090304 244 0.171
multicellular organismal metabolic process GO:0044236 2 0.169
response to corticosteroid GO:0031960 1 0.167
embryonic organ morphogenesis GO:0048562 274 0.163
regionalization GO:0003002 274 0.162
specification of symmetry GO:0009799 204 0.160
system process GO:0003008 185 0.150
Rat
cell migration GO:0016477 237 0.149
Rat
blood vessel endothelial cell migration GO:0043534 18 0.146
cellular component morphogenesis GO:0032989 336 0.143
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.134
regulation of gene expression GO:0010468 265 0.128
regulation of signaling GO:0023051 235 0.125
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.122
sensory organ morphogenesis GO:0090596 200 0.120
heterocycle metabolic process GO:0046483 290 0.119
single organism localization GO:1902578 225 0.116
notochord development GO:0030903 54 0.111
neuron projection extension GO:1990138 45 0.111
cellular divalent inorganic cation homeostasis GO:0072503 13 0.109
Rat
regulation of cell communication GO:0010646 232 0.107
Human Mouse
gene expression GO:0010467 252 0.105
determination of heart left right asymmetry GO:0061371 117 0.104
epiboly GO:0090504 41 0.104
monoamine transport GO:0015844 1 0.102
generation of neurons GO:0048699 385 0.101
Zebrafish Rat
nitrogen compound metabolic process GO:0006807 319 0.101
cellular component biogenesis GO:0044085 178 0.098
Mouse
neuron neuron synaptic transmission GO:0007270 1 0.097
cell morphogenesis GO:0000902 289 0.095
Zebrafish
death GO:0016265 121 0.093
Rat
single organism transport GO:0044765 206 0.093
response to ketone GO:1901654 1 0.093
sensory perception of smell GO:0007608 2 0.092
mitotic cell cycle process GO:1903047 48 0.089
nucleobase containing compound metabolic process GO:0006139 274 0.088
organic cyclic compound metabolic process GO:1901360 301 0.087
regulation of multicellular organismal process GO:0051239 277 0.085
Rat
central nervous system development GO:0007417 387 0.084
cellular biosynthetic process GO:0044249 286 0.081
epithelial tube morphogenesis GO:0060562 148 0.079
transmission of nerve impulse GO:0019226 19 0.079
Rat
developmental cell growth GO:0048588 52 0.077
brain development GO:0007420 293 0.075
neuronal action potential GO:0019228 18 0.074
Rat
aging GO:0007568 2 0.074
chordate embryonic development GO:0043009 271 0.073
eye morphogenesis GO:0048592 144 0.073
chemical homeostasis GO:0048878 49 0.073
Rat
transport GO:0006810 220 0.072
multicellular organism growth GO:0035264 4 0.072
regulation of dna replication GO:0006275 3 0.072
response to abiotic stimulus GO:0009628 122 0.071
Rat
mitotic cell cycle GO:0000278 64 0.070
negative regulation of biological process GO:0048519 304 0.069
Rat
cellular macromolecule metabolic process GO:0044260 391 0.069
Mouse
chemotaxis GO:0006935 104 0.068
Rat
developmental growth GO:0048589 166 0.068
germ line stem cell maintenance GO:0030718 2 0.067
amine metabolic process GO:0009308 2 0.067
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.067
Zebrafish
cellular calcium ion homeostasis GO:0006874 13 0.066
Rat
transcription dna templated GO:0006351 181 0.062
macromolecule localization GO:0033036 54 0.062
positive regulation of locomotion GO:0040017 14 0.062
Rat
growth GO:0040007 174 0.061
head development GO:0060322 303 0.061
hemopoiesis GO:0030097 183 0.060
negative regulation of rho protein signal transduction GO:0035024 1 0.060
regulation of collagen metabolic process GO:0010712 2 0.059
organic acid metabolic process GO:0006082 31 0.058
response to radiation GO:0009314 51 0.058
positive regulation of cytokine production GO:0001819 2 0.056
tissue regeneration GO:0042246 74 0.056
response to external stimulus GO:0009605 264 0.055
Rat
somatic muscle development GO:0007525 4 0.054
nucleocytoplasmic transport GO:0006913 4 0.054
phagocytosis GO:0006909 3 0.053
cation homeostasis GO:0055080 33 0.053
Rat
larval heart development GO:0007508 2 0.053
camera type eye development GO:0043010 222 0.052
regulation of cell proliferation GO:0042127 37 0.052
programmed cell death GO:0012501 119 0.052
Rat
embryonic heart tube development GO:0035050 133 0.052
neuron differentiation GO:0030182 353 0.052
Zebrafish Rat
positive regulation of cellular process GO:0048522 201 0.050
Human Mouse Rat
intracellular receptor signaling pathway GO:0030522 30 0.050
regulation of cellular metabolic process GO:0031323 320 0.049
Mouse
cell motility GO:0048870 244 0.049
Rat
regulation of apoptotic process GO:0042981 98 0.048
Rat
regulation of cell death GO:0010941 103 0.047
Rat
establishment of localization in cell GO:0051649 77 0.047
regulation of primary metabolic process GO:0080090 311 0.047
Mouse
multicellular organismal macromolecule metabolic process GO:0044259 2 0.047
cell death GO:0008219 121 0.046
Rat
response to light stimulus GO:0009416 46 0.044
response to nutrient GO:0007584 3 0.044
gastrulation with mouth forming second GO:0001702 44 0.044
cellular response to radiation GO:0071478 4 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
embryonic heart tube morphogenesis GO:0003143 108 0.042
neuron projection guidance GO:0097485 86 0.041
positive regulation of cellular amine metabolic process GO:0033240 0 0.041
response to chemical GO:0042221 320 0.040
Rat
fin regeneration GO:0031101 51 0.040
carboxylic acid metabolic process GO:0019752 22 0.039
protein localization to nucleus GO:0034504 3 0.039
g1 s transition of mitotic cell cycle GO:0000082 1 0.038
appendage development GO:0048736 80 0.038
defense response GO:0006952 47 0.038
stem cell maintenance GO:0019827 4 0.038
axon ensheathment GO:0008366 18 0.038
Rat
organelle organization GO:0006996 227 0.037
formation of primary germ layer GO:0001704 62 0.037
response to glucocorticoid GO:0051384 1 0.037
regulation of protein catabolic process GO:0042176 1 0.037
regulation of transcription dna templated GO:0006355 213 0.037
liver development GO:0001889 96 0.036
skeletal system development GO:0001501 181 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.035
gland development GO:0048732 143 0.035
immune system development GO:0002520 191 0.035
actin filament bundle organization GO:0061572 6 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
regulation of macromolecule metabolic process GO:0060255 317 0.034
Mouse
response to vitamin b3 GO:0033552 2 0.034
cellular localization GO:0051641 97 0.034
angiogenesis GO:0001525 158 0.033
regulation of anatomical structure morphogenesis GO:0022603 130 0.033
taxis GO:0042330 109 0.033
Rat
immune system process GO:0002376 241 0.033
cellular amine metabolic process GO:0044106 2 0.032
bmp signaling pathway GO:0030509 52 0.032
kupffer s vesicle development GO:0070121 50 0.032
small gtpase mediated signal transduction GO:0007264 8 0.032
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.032
cell cycle GO:0007049 93 0.031
regulation of signal transduction GO:0009966 225 0.031
Human Mouse
regeneration GO:0031099 91 0.031
cell projection morphogenesis GO:0048858 244 0.031
Zebrafish
axon guidance GO:0007411 86 0.031
muscle structure development GO:0061061 196 0.031
neurological system process GO:0050877 62 0.030
Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
regulation of developmental process GO:0050793 247 0.030
Rat
regulation of metabolic process GO:0019222 359 0.030
Mouse
neuron projection morphogenesis GO:0048812 161 0.030
Zebrafish
collagen metabolic process GO:0032963 2 0.029
establishment of blood brain barrier GO:0060856 2 0.028
multicellular organismal signaling GO:0035637 22 0.028
Rat
post embryonic organ development GO:0048569 4 0.028
cell adhesion mediated by integrin GO:0033627 1 0.028
pericardium development GO:0060039 1 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
nuclear transport GO:0051169 4 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
fin development GO:0033333 77 0.028
cognition GO:0050890 1 0.027
camera type eye morphogenesis GO:0048593 108 0.027
response to wounding GO:0009611 116 0.027
homeostasis of number of cells GO:0048872 62 0.027
heart looping GO:0001947 94 0.026
metal ion homeostasis GO:0055065 26 0.026
Rat
regulation of rna metabolic process GO:0051252 224 0.026
erk1 and erk2 cascade GO:0070371 4 0.026
cell cycle g1 s phase transition GO:0044843 1 0.026
cellular ion homeostasis GO:0006873 17 0.026
Rat
establishment of protein localization to organelle GO:0072594 4 0.026
regulation of rho protein signal transduction GO:0035023 2 0.025
Mouse
positive regulation of synapse assembly GO:0051965 1 0.025
neuron development GO:0048666 262 0.025
Zebrafish Rat
cellular macromolecule biosynthetic process GO:0034645 224 0.025
organelle assembly GO:0070925 110 0.025
response to organic substance GO:0010033 153 0.025
cellular protein metabolic process GO:0044267 129 0.025
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
wound healing GO:0042060 90 0.024
protein phosphorylation GO:0006468 47 0.024
Mouse
axon extension GO:0048675 45 0.024
nuclear import GO:0051170 3 0.024
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
Mouse
mesoderm development GO:0007498 88 0.023
negative regulation of response to stimulus GO:0048585 104 0.023
peptidyl serine phosphorylation GO:0018105 1 0.023
cartilage development GO:0051216 96 0.023
cell growth GO:0016049 57 0.023
protein import GO:0017038 3 0.023
phosphorus metabolic process GO:0006793 109 0.023
Mouse
body morphogenesis GO:0010171 16 0.023
larval development GO:0002164 2 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
positive regulation of biological process GO:0048518 253 0.022
Human Zebrafish Mouse Rat
myeloid cell homeostasis GO:0002262 56 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
stem cell differentiation GO:0048863 117 0.022
rna metabolic process GO:0016070 219 0.022
axonogenesis GO:0007409 152 0.022
Zebrafish
branched chain amino acid metabolic process GO:0009081 1 0.022
regulation of programmed cell death GO:0043067 101 0.022
Rat
protein metabolic process GO:0019538 183 0.022
Mouse
regulation of endocytosis GO:0030100 7 0.022
protein localization GO:0008104 40 0.022
regulation of protein metabolic process GO:0051246 56 0.021
Mouse
ras protein signal transduction GO:0007265 7 0.021
Mouse
intracellular signal transduction GO:0035556 85 0.021
Human Mouse
retina development in camera type eye GO:0060041 146 0.021
biological adhesion GO:0022610 40 0.021
protein targeting to nucleus GO:0044744 3 0.021
oxidative demethylation GO:0070989 1 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
cell adhesion GO:0007155 40 0.021
single organism cell adhesion GO:0098602 29 0.020
negative regulation of dna metabolic process GO:0051053 4 0.020
detection of abiotic stimulus GO:0009582 24 0.020
protein modification process GO:0036211 100 0.020
Mouse
negative regulation of cellular process GO:0048523 283 0.020
Rat
regulation of metal ion transport GO:0010959 4 0.020
regulation of inflammatory response GO:0050727 2 0.020
regulation of cell motility GO:2000145 46 0.020
Rat
apoptotic process GO:0006915 116 0.020
Rat
serotonin transport GO:0006837 1 0.020
positive regulation of cell migration GO:0030335 11 0.020
Rat
positive regulation of multicellular organismal process GO:0051240 52 0.020
Rat
response to lipid GO:0033993 60 0.020
cell projection assembly GO:0030031 64 0.019
Mouse
cell matrix adhesion GO:0007160 4 0.019
cytoskeleton organization GO:0007010 96 0.019
cellular chemical homeostasis GO:0055082 17 0.019
Rat
protein homooligomerization GO:0051260 3 0.019
heart morphogenesis GO:0003007 156 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
response to organic cyclic compound GO:0014070 51 0.018
cellular response to nutrient levels GO:0031669 2 0.018
muscle attachment GO:0016203 9 0.018
modulation by virus of host morphology or physiology GO:0019048 1 0.018
insulin like growth factor receptor signaling pathway GO:0048009 4 0.018
striated muscle tissue development GO:0014706 110 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
positive regulation of transport GO:0051050 2 0.017
appendage morphogenesis GO:0035107 56 0.017
cell cycle process GO:0022402 53 0.017
cell migration in hindbrain GO:0021535 7 0.017
single organism metabolic process GO:0044710 217 0.017
Zebrafish Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.016
amino acid transport GO:0006865 2 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
cellular ketone metabolic process GO:0042180 11 0.016
detection of external stimulus GO:0009581 24 0.016
cellular homeostasis GO:0019725 26 0.016
Rat
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
single organism organelle organization GO:1902589 199 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
regulation of multicellular organismal metabolic process GO:0044246 2 0.016
regulation of cellular component organization GO:0051128 86 0.016
Rat
axon development GO:0061564 166 0.016
Zebrafish
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
actin cytoskeleton organization GO:0030036 63 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
Zebrafish
stress fiber assembly GO:0043149 5 0.016
phosphorylation GO:0016310 69 0.016
Mouse
erythrocyte homeostasis GO:0034101 55 0.016
regulation of glycoprotein biosynthetic process GO:0010559 3 0.015
protein import into nucleus GO:0006606 3 0.015
muscle system process GO:0003012 20 0.015
actomyosin structure organization GO:0031032 53 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
response to estrogen GO:0043627 27 0.015
pyruvate metabolic process GO:0006090 1 0.015
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
fin morphogenesis GO:0033334 53 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
behavior GO:0007610 74 0.015
Zebrafish Rat
cellular metal ion homeostasis GO:0006875 16 0.015
Rat
regulation of cell shape GO:0008360 1 0.015
single organism behavior GO:0044708 24 0.015
cellular transition metal ion homeostasis GO:0046916 3 0.014
ion homeostasis GO:0050801 41 0.014
Rat
positive regulation of catabolic process GO:0009896 4 0.014
negative regulation of growth rate GO:0045967 1 0.014
regulation of molecular function GO:0065009 70 0.014
Mouse
rho protein signal transduction GO:0007266 5 0.014
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
reactive oxygen species biosynthetic process GO:1903409 1 0.014
regulation of lipase activity GO:0060191 2 0.014
detection of light stimulus GO:0009583 12 0.014
negative regulation of cell death GO:0060548 60 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
dicarboxylic acid metabolic process GO:0043648 1 0.014
response to estradiol GO:0032355 6 0.014
embryonic hemopoiesis GO:0035162 53 0.014
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.014
defense response to fungus GO:0050832 2 0.014
negative regulation of protein transport GO:0051224 3 0.013
cellular respiration GO:0045333 3 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
regulation of transport GO:0051049 45 0.013
protein complex biogenesis GO:0070271 30 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
epidermis development GO:0008544 48 0.013
tissue remodeling GO:0048771 4 0.013
response to fatty acid GO:0070542 5 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
positive regulation of signaling GO:0023056 56 0.013
Human Mouse
cell part morphogenesis GO:0032990 246 0.013
Zebrafish
protein complex assembly GO:0006461 30 0.013
cell fate commitment GO:0045165 99 0.013
cranial nerve development GO:0021545 42 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.012
regulation of protein localization to plasma membrane GO:1903076 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
striated muscle cell differentiation GO:0051146 129 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
response to stress GO:0006950 263 0.012
oxoacid metabolic process GO:0043436 31 0.012
cell proliferation GO:0008283 80 0.012
hard palate development GO:0060022 4 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
Mouse
neuron projection development GO:0031175 180 0.012
Zebrafish Rat
lipid storage GO:0019915 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
Rat
response to alcohol GO:0097305 14 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
regulation of localization GO:0032879 104 0.012
Rat
protein complex subunit organization GO:0071822 46 0.012
detection of visible light GO:0009584 12 0.012
regulation of protein localization to nucleus GO:1900180 2 0.011
pancreas development GO:0031016 84 0.011
centrosome organization GO:0051297 1 0.011
muscle organ development GO:0007517 101 0.011
cell projection organization GO:0030030 284 0.011
Zebrafish Mouse Rat
negative regulation of feeding behavior GO:2000252 2 0.011
positive regulation of cellular component organization GO:0051130 13 0.011
Rat
neutral amino acid transport GO:0015804 2 0.011
regulation of synapse organization GO:0050807 3 0.011
endoderm formation GO:0001706 29 0.011
regulation of dna recombination GO:0000018 2 0.011
connective tissue development GO:0061448 99 0.011
oxidation reduction process GO:0055114 41 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
protein acetylation GO:0006473 2 0.011
extracellular matrix organization GO:0030198 27 0.011
skeletal muscle organ development GO:0060538 78 0.011
rna 3 end processing GO:0031123 2 0.011
hepaticobiliary system development GO:0061008 98 0.010
cellular modified amino acid metabolic process GO:0006575 3 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
membrane invagination GO:0010324 1 0.010
embryonic appendage morphogenesis GO:0035113 30 0.010
iron ion homeostasis GO:0055072 4 0.010
cation transport GO:0006812 81 0.010
protein secretion GO:0009306 1 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
regulation of cellular protein metabolic process GO:0032268 52 0.010
Mouse

lpar1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.057
inherited metabolic disorder DOID:655 0 0.057
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017
nervous system disease DOID:863 0 0.012