Danio rerio

66 known processes

mitfa

microphthalmia-associated transcription factor a

(Aliases: z3A.1,nacre)

mitfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigmentation GO:0043473 85 1.000
pigment cell differentiation GO:0050931 38 1.000
developmental pigmentation GO:0048066 48 0.999
regulation of retina development in camera type eye GO:1902866 2 0.986
melanocyte differentiation GO:0030318 26 0.983
regulation of neural retina development GO:0061074 2 0.982
neuroepithelial cell differentiation GO:0060563 26 0.975
aromatic amino acid family metabolic process GO:0009072 1 0.962
xanthophore differentiation GO:0050936 3 0.961
melanin biosynthetic process GO:0042438 1 0.953
regulation of developmental pigmentation GO:0048070 6 0.948
positive regulation of macrophage chemotaxis GO:0010759 1 0.938
neural crest cell development GO:0014032 62 0.917
phenol containing compound biosynthetic process GO:0046189 4 0.909
tyrosine metabolic process GO:0006570 1 0.882
stem cell differentiation GO:0048863 117 0.867
dopamine biosynthetic process GO:0042416 2 0.858
catecholamine biosynthetic process GO:0042423 2 0.858
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.813
localization of cell GO:0051674 244 0.778
secondary metabolite biosynthetic process GO:0044550 1 0.762
neural crest cell migration GO:0001755 42 0.759
heart development GO:0007507 313 0.745
pigment granule organization GO:0048753 4 0.744
microglia differentiation GO:0014004 1 0.741
melanosome organization GO:0032438 4 0.733
mesenchymal cell development GO:0014031 78 0.721
regulation of developmental process GO:0050793 247 0.707
Mouse
regulation of macrophage chemotaxis GO:0010758 1 0.699
mesenchymal cell differentiation GO:0048762 87 0.666
osteoclast development GO:0036035 1 0.665
tissue remodeling GO:0048771 4 0.638
Mouse
pigment metabolic process GO:0042440 12 0.631
neural crest cell differentiation GO:0014033 72 0.630
dopamine metabolic process GO:0042417 2 0.625
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.614
regulation of mononuclear cell migration GO:0071675 1 0.591
catechol containing compound metabolic process GO:0009712 2 0.582
catechol containing compound biosynthetic process GO:0009713 2 0.547
melanin metabolic process GO:0006582 2 0.534
embryonic organ morphogenesis GO:0048562 274 0.532
retina development in camera type eye GO:0060041 146 0.528
epithelial cell differentiation GO:0030855 116 0.511
gland development GO:0048732 143 0.503
positive regulation of cell proliferation GO:0008284 15 0.459
secondary metabolic process GO:0019748 3 0.452
cellular component movement GO:0006928 335 0.445
catecholamine metabolic process GO:0006584 2 0.431
pigment biosynthetic process GO:0046148 9 0.423
organic cyclic compound biosynthetic process GO:1901362 223 0.421
auditory receptor cell fate commitment GO:0009912 4 0.416
cellular pigmentation GO:0033059 30 0.408
regulation of multicellular organismal development GO:2000026 223 0.386
Mouse
striated muscle tissue development GO:0014706 110 0.385
mononuclear cell migration GO:0071674 1 0.376
negative regulation of cellular process GO:0048523 283 0.372
Human Mouse
mesenchyme development GO:0060485 127 0.366
positive regulation of retina development in camera type eye GO:1902868 1 0.361
leukocyte differentiation GO:0002521 25 0.360
Mouse
sensory organ morphogenesis GO:0090596 200 0.344
anterior lateral line system development GO:0048898 9 0.340
alpha amino acid metabolic process GO:1901605 3 0.339
single organism metabolic process GO:0044710 217 0.331
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.323
Human Mouse Worm
negative regulation of programmed cell death GO:0043069 58 0.322
Mouse
embryonic heart tube development GO:0035050 133 0.319
positive regulation of neural retina development GO:0061075 1 0.307
muscle organ development GO:0007517 101 0.305
cellular amino acid metabolic process GO:0006520 7 0.304
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.303
glycolipid metabolic process GO:0006664 8 0.290
aromatic compound biosynthetic process GO:0019438 217 0.289
venous blood vessel development GO:0060841 9 0.277
biosynthetic process GO:0009058 294 0.269
organic substance biosynthetic process GO:1901576 289 0.266
intracellular signal transduction GO:0035556 85 0.265
regulation of macromolecule metabolic process GO:0060255 317 0.265
phenol containing compound metabolic process GO:0018958 5 0.260
heart contraction GO:0060047 71 0.258
macrophage chemotaxis GO:0048246 3 0.250
stem cell development GO:0048864 82 0.246
atrial ventricular junction remodeling GO:0003294 2 0.243
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.242
positive regulation of macromolecule metabolic process GO:0010604 93 0.231
Human Mouse Worm
generation of neurons GO:0048699 385 0.229
chordate embryonic development GO:0043009 271 0.227
regulation of primary metabolic process GO:0080090 311 0.227
negative regulation of biological process GO:0048519 304 0.227
Human Mouse
embryonic viscerocranium morphogenesis GO:0048703 52 0.225
sensory organ development GO:0007423 393 0.211
Mouse
posterior lateral line nerve glial cell development GO:0048941 5 0.202
eye development GO:0001654 277 0.199
Mouse
regulation of multicellular organismal process GO:0051239 277 0.199
Mouse
cell morphogenesis GO:0000902 289 0.198
morphogenesis of an epithelium GO:0002009 333 0.198
nephron tubule morphogenesis GO:0072078 1 0.196
auditory receptor cell fate determination GO:0042668 2 0.195
sensory perception of mechanical stimulus GO:0050954 16 0.193
cellular lipid metabolic process GO:0044255 36 0.188
cell morphogenesis involved in differentiation GO:0000904 195 0.188
immune system development GO:0002520 191 0.188
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.185
skeletal muscle organ development GO:0060538 78 0.184
cellular protein modification process GO:0006464 100 0.181
death GO:0016265 121 0.180
Mouse
skeletal muscle tissue development GO:0007519 67 0.179
transport GO:0006810 220 0.172
muscle structure development GO:0061061 196 0.171
carboxylic acid metabolic process GO:0019752 22 0.170
neural retina development GO:0003407 49 0.164
cell motility GO:0048870 244 0.164
tube morphogenesis GO:0035239 349 0.160
neurological system process GO:0050877 62 0.158
embryonic organ development GO:0048568 381 0.157
heart process GO:0003015 71 0.157
myeloid cell differentiation GO:0030099 86 0.155
Mouse
cell proliferation GO:0008283 80 0.155
Mouse
cellular amine metabolic process GO:0044106 2 0.154
signal transduction GO:0007165 455 0.145
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.143
cardiac chamber development GO:0003205 19 0.143
eye pigmentation GO:0048069 4 0.141
muscle tissue development GO:0060537 110 0.141
regulation of cell differentiation GO:0045595 142 0.141
Mouse
circulatory system process GO:0003013 87 0.140
regulation of cell proliferation GO:0042127 37 0.138
Mouse
limb bud formation GO:0060174 2 0.136
cellular component morphogenesis GO:0032989 336 0.134
posterior lateral line nerve development GO:0048918 8 0.133
central nervous system development GO:0007417 387 0.132
positive regulation of metabolic process GO:0009893 108 0.131
Human Mouse Worm
anterior lateral line nerve glial cell differentiation GO:0048913 3 0.130
antimicrobial humoral response GO:0019730 2 0.127
myelination of posterior lateral line nerve axons GO:0048932 5 0.126
osteoclast differentiation GO:0030316 1 0.125
Mouse
epithelial to mesenchymal transition GO:0001837 21 0.123
embryonic limb morphogenesis GO:0030326 2 0.122
fin development GO:0033333 77 0.120
camera type eye morphogenesis GO:0048593 108 0.119
embryonic skeletal system morphogenesis GO:0048704 93 0.118
anterior lateral line nerve glial cell development GO:0048939 3 0.118
b cell differentiation GO:0030183 1 0.117
sensory perception of sound GO:0007605 9 0.116
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.113
negative regulation of apoptotic process GO:0043066 55 0.113
Mouse
regulation of cell morphogenesis GO:0022604 42 0.112
bone remodeling GO:0046849 2 0.111
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.111
determination of intestine left right asymmetry GO:0071908 2 0.108
positive regulation of rna biosynthetic process GO:1902680 57 0.106
Human Mouse Worm
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.105
oligodendrocyte cell fate specification GO:0021778 4 0.102
organism emergence from protective structure GO:0071684 4 0.102
proepicardium development GO:0003342 4 0.100
regulation of apoptotic process GO:0042981 98 0.097
Mouse
camera type eye photoreceptor cell differentiation GO:0060219 19 0.097
anterior lateral line nerve development GO:0048909 4 0.097
glucose import GO:0046323 2 0.094
neuron differentiation GO:0030182 353 0.093
regulation of transcription dna templated GO:0006355 213 0.093
single organism transport GO:0044765 206 0.093
negative regulation of cell death GO:0060548 60 0.093
Mouse
segment polarity determination GO:0007367 1 0.092
blood vessel endothelial cell migration GO:0043534 18 0.092
cellular component maintenance GO:0043954 3 0.092
nucleic acid metabolic process GO:0090304 244 0.091
thyroid gland development GO:0030878 12 0.091
pharyngeal muscle development GO:0043282 4 0.090
photoreceptor cell fate specification GO:0043704 1 0.090
retinal pigment epithelium development GO:0003406 8 0.089
positive regulation of myeloid cell differentiation GO:0045639 2 0.088
regulation of anatomical structure morphogenesis GO:0022603 130 0.087
exocrine system development GO:0035272 28 0.087
urogenital system development GO:0001655 97 0.086
lamellipodium assembly GO:0030032 1 0.086
myelination of anterior lateral line nerve axons GO:0048914 3 0.085
glial cell differentiation GO:0010001 42 0.085
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.085
immune system process GO:0002376 241 0.085
Mouse
response to external stimulus GO:0009605 264 0.084
Worm
regulation of establishment of protein localization GO:0070201 4 0.084
neuron fate commitment GO:0048663 26 0.082
positive regulation of leukocyte differentiation GO:1902107 1 0.082
response to biotic stimulus GO:0009607 97 0.081
Worm
schwann cell development GO:0014044 9 0.080
transcription dna templated GO:0006351 181 0.080
homeostasis of number of cells GO:0048872 62 0.079
phosphatidylinositol mediated signaling GO:0048015 2 0.078
nitrogen compound metabolic process GO:0006807 319 0.078
positive regulation of rna metabolic process GO:0051254 59 0.078
Human Mouse Worm
positive regulation of immune effector process GO:0002699 3 0.076
cardiogenic plate morphogenesis GO:0003142 1 0.076
spinal cord development GO:0021510 46 0.075
cell proliferation in forebrain GO:0021846 3 0.075
positive regulation of neural precursor cell proliferation GO:2000179 1 0.074
developmental programmed cell death GO:0010623 4 0.074
regulation of cell shape GO:0008360 1 0.074
camera type eye development GO:0043010 222 0.074
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.072
cell differentiation in spinal cord GO:0021515 40 0.072
myelination of lateral line nerve axons GO:0048897 5 0.071
neuronal action potential GO:0019228 18 0.071
b cell activation GO:0042113 2 0.071
cellular macromolecule metabolic process GO:0044260 391 0.071
lymphangiogenesis GO:0001946 25 0.070
epithelial tube morphogenesis GO:0060562 148 0.068
regulation of cellular amine metabolic process GO:0033238 0 0.068
regulation of signaling GO:0023051 235 0.067
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.067
cell fate commitment GO:0045165 99 0.066
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.065
Mouse
axon development GO:0061564 166 0.065
melanocyte migration GO:0097324 4 0.064
organic acid metabolic process GO:0006082 31 0.064
t cell differentiation GO:0030217 6 0.064
jak stat cascade GO:0007259 5 0.063
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.063
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.063
embryonic heart tube formation GO:0003144 1 0.063
immune response GO:0006955 28 0.063
regulation of stem cell proliferation GO:0072091 2 0.063
regulation of myeloid cell differentiation GO:0045637 8 0.063
Mouse
mitotic cell cycle phase transition GO:0044772 9 0.063
regulation of localization GO:0032879 104 0.062
positive regulation of jak stat cascade GO:0046427 2 0.061
larval development GO:0002164 2 0.061
lateral line nerve glial cell morphogenesis involved in differentiation GO:0048938 5 0.060
glial cell migration GO:0008347 3 0.059
stem cell proliferation GO:0072089 4 0.058
programmed cell death GO:0012501 119 0.058
Mouse
cellular ketone metabolic process GO:0042180 11 0.058
determination of heart left right asymmetry GO:0061371 117 0.057
iridophore differentiation GO:0050935 9 0.057
hemopoiesis GO:0030097 183 0.057
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.057
endocardium development GO:0003157 9 0.057
photoreceptor cell fate commitment GO:0046552 1 0.056
response to stress GO:0006950 263 0.055
Worm
embryonic heart tube morphogenesis GO:0003143 108 0.055
cellular aromatic compound metabolic process GO:0006725 295 0.054
regulation of protein transport GO:0051223 3 0.054
positive regulation of epithelial cell differentiation GO:0030858 2 0.054
oxoacid metabolic process GO:0043436 31 0.054
regulation of signal transduction GO:0009966 225 0.053
positive regulation of cellular amine metabolic process GO:0033240 0 0.053
myeloid cell development GO:0061515 32 0.053
swimming behavior GO:0036269 8 0.052
single organism localization GO:1902578 225 0.052
neuron development GO:0048666 262 0.052
brain development GO:0007420 293 0.051
optic nerve development GO:0021554 15 0.051
regulation of jak stat cascade GO:0046425 3 0.051
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.050
vasculature development GO:0001944 278 0.050
central nervous system neuron differentiation GO:0021953 74 0.050
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.050
embryonic cranial skeleton morphogenesis GO:0048701 90 0.050
positive regulation of nucleic acid templated transcription GO:1903508 57 0.049
Human Mouse Worm
negative regulation of nucleic acid templated transcription GO:1903507 45 0.049
Human
regulation of metabolic process GO:0019222 359 0.049
appendage development GO:0048736 80 0.048
heart morphogenesis GO:0003007 156 0.048
production of molecular mediator of immune response GO:0002440 2 0.048
negative regulation of catabolic process GO:0009895 3 0.048
cellular response to molecule of bacterial origin GO:0071219 3 0.048
hexose transport GO:0008645 6 0.046
establishment of monopolar cell polarity GO:0061162 2 0.046
establishment of protein localization to organelle GO:0072594 4 0.045
neuroblast proliferation GO:0007405 2 0.045
regulation of cell communication GO:0010646 232 0.045
selective angioblast sprouting GO:0035474 5 0.045
cell projection morphogenesis GO:0048858 244 0.045
nephron epithelium morphogenesis GO:0072088 1 0.044
regulation of programmed cell death GO:0043067 101 0.044
Mouse
positive regulation of map kinase activity GO:0043406 3 0.044
regulation of leukocyte differentiation GO:1902105 5 0.044
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
organonitrogen compound metabolic process GO:1901564 74 0.044
g1 s transition of mitotic cell cycle GO:0000082 1 0.044
inositol lipid mediated signaling GO:0048017 2 0.043
positive regulation of myeloid leukocyte differentiation GO:0002763 1 0.043
post embryonic organ morphogenesis GO:0048563 1 0.043
phosphate containing compound metabolic process GO:0006796 108 0.043
regulation of cellular biosynthetic process GO:0031326 245 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.042
regulation of biological quality GO:0065008 263 0.042
Worm
response to chemical GO:0042221 320 0.042
ventral spinal cord interneuron specification GO:0021521 3 0.041
immune effector process GO:0002252 23 0.041
regulation of cytokine production GO:0001817 3 0.041
polarized epithelial cell differentiation GO:0030859 4 0.040
mitochondrion organization GO:0007005 4 0.040
myeloid cell homeostasis GO:0002262 56 0.040
endocardium formation GO:0060214 1 0.040
cellular biosynthetic process GO:0044249 286 0.040
positive regulation of cellular metabolic process GO:0031325 94 0.040
Human Mouse Worm
lymph vessel morphogenesis GO:0036303 25 0.039
cell type specific apoptotic process GO:0097285 22 0.039
regulation of cellular metabolic process GO:0031323 320 0.039
innate immune response GO:0045087 13 0.039
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.038
cell cell junction maintenance GO:0045217 1 0.038
regulation of cardiac muscle contraction GO:0055117 2 0.038
negative regulation of multicellular organismal process GO:0051241 69 0.038
epithelial tube formation GO:0072175 19 0.038
appendage morphogenesis GO:0035107 56 0.038
septum transversum development GO:0003343 4 0.038
positive regulation of biological process GO:0048518 253 0.037
Human Mouse Worm
olfactory placode development GO:0071698 12 0.037
regulation of autophagy GO:0010506 3 0.037
Worm
protein complex subunit organization GO:0071822 46 0.037
Human
vasculogenesis GO:0001570 41 0.037
cell part morphogenesis GO:0032990 246 0.037
regulation of cell cycle phase transition GO:1901987 8 0.037
bmp signaling pathway GO:0030509 52 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
locomotion GO:0040011 313 0.036
biological adhesion GO:0022610 40 0.036
leukocyte proliferation GO:0070661 1 0.036
amine metabolic process GO:0009308 2 0.036
tube formation GO:0035148 25 0.036
positive regulation of cellular process GO:0048522 201 0.035
Human Mouse Worm
determination of bilateral symmetry GO:0009855 204 0.035
anterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048940 3 0.035
lipid metabolic process GO:0006629 52 0.035
central nervous system neuron development GO:0021954 29 0.035
cell killing GO:0001906 2 0.034
hindbrain morphogenesis GO:0021575 22 0.034
autophagy GO:0006914 4 0.034
Worm
epithalamus development GO:0021538 10 0.034
embryonic skeletal joint morphogenesis GO:0060272 3 0.033
sensory perception GO:0007600 39 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.033
Human
liposaccharide metabolic process GO:1903509 8 0.033
extrinsic apoptotic signaling pathway GO:0097191 3 0.033
fin regeneration GO:0031101 51 0.033
macromolecular complex subunit organization GO:0043933 74 0.033
Human
epithelium migration GO:0090132 25 0.033
negative regulation of signal transduction GO:0009968 94 0.033
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.032
negative regulation of macromolecule metabolic process GO:0010605 76 0.032
Human
regulation of neural precursor cell proliferation GO:2000177 3 0.032
regulation of immune response GO:0050776 14 0.032
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.031
regulation of heart contraction GO:0008016 32 0.031
nephron morphogenesis GO:0072028 2 0.031
negative regulation of biosynthetic process GO:0009890 55 0.031
Human
mesoderm development GO:0007498 88 0.031
glucose transport GO:0015758 6 0.031
system process GO:0003008 185 0.030
actin cytoskeleton organization GO:0030036 63 0.030
cell fate specification GO:0001708 68 0.030
tissue regeneration GO:0042246 74 0.030
organic hydroxy compound biosynthetic process GO:1901617 6 0.030
response to endogenous stimulus GO:0009719 83 0.029
sprouting angiogenesis GO:0002040 53 0.029
nucleic acid templated transcription GO:0097659 181 0.029
trabecula formation GO:0060343 2 0.029
organ regeneration GO:0031100 1 0.029
organic hydroxy compound metabolic process GO:1901615 16 0.029
chemosensory behavior GO:0007635 1 0.029
ear morphogenesis GO:0042471 64 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.028
vesicle organization GO:0016050 6 0.028
apoptotic signaling pathway GO:0097190 23 0.028
response to external biotic stimulus GO:0043207 97 0.028
Worm
negative regulation of metabolic process GO:0009892 86 0.028
Human
small molecule metabolic process GO:0044281 77 0.028
positive regulation of stem cell proliferation GO:2000648 1 0.028
lymphocyte differentiation GO:0030098 9 0.027
melanocyte apoptotic process GO:1902362 2 0.027
regulation of catalytic activity GO:0050790 55 0.027
negative regulation of oocyte development GO:0060283 2 0.027
cellular component biogenesis GO:0044085 178 0.027
Human
peptide metabolic process GO:0006518 1 0.027
pancreatic a cell development GO:0003322 2 0.027
hindbrain development GO:0030902 91 0.027
cell migration involved in heart development GO:0060973 22 0.026
cell cycle g1 s phase transition GO:0044843 1 0.026
g2 dna damage checkpoint GO:0031572 3 0.026
specification of organ identity GO:0010092 2 0.026
macromolecule modification GO:0043412 111 0.026
negative regulation of neural precursor cell proliferation GO:2000178 1 0.026
posterior lateral line nerve glial cell differentiation GO:0048931 5 0.026
schwann cell differentiation GO:0014037 9 0.026
semicircular canal morphogenesis GO:0048752 18 0.026
macroautophagy GO:0016236 1 0.026
cardiac atrium morphogenesis GO:0003209 2 0.025
regulation of endothelial cell differentiation GO:0045601 3 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.025
cellular response to hormone stimulus GO:0032870 39 0.025
cardiac chamber formation GO:0003207 4 0.025
mitotic g2 m transition checkpoint GO:0044818 3 0.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.024
transition metal ion transport GO:0000041 6 0.024
cell projection organization GO:0030030 284 0.024
regulation of bone remodeling GO:0046850 2 0.024
regulation of epithelial to mesenchymal transition GO:0010717 3 0.024
cellular protein metabolic process GO:0044267 129 0.024
positive regulation of notch signaling pathway GO:0045747 3 0.024
positive regulation of immune response GO:0050778 11 0.024
retinal cone cell differentiation GO:0042670 12 0.024
posterior lateral line neuromast development GO:0048919 20 0.024
retinal rod cell development GO:0046548 4 0.023
megakaryocyte development GO:0035855 1 0.023
regulation of erk1 and erk2 cascade GO:0070372 4 0.023
negative regulation of cell cycle phase transition GO:1901988 5 0.023
cellular response to biotic stimulus GO:0071216 3 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.023
Human Mouse Worm
vestibular receptor cell differentiation GO:0060114 3 0.023
adrenal gland development GO:0030325 10 0.023
regulation of mapk cascade GO:0043408 14 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
forebrain regionalization GO:0021871 4 0.022
intrinsic apoptotic signaling pathway GO:0097193 20 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
positive regulation of leukocyte chemotaxis GO:0002690 1 0.022
retina morphogenesis in camera type eye GO:0060042 79 0.022
exocytosis GO:0006887 1 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
response to lipid GO:0033993 60 0.021
regulation of tissue remodeling GO:0034103 2 0.021
neuron projection guidance GO:0097485 86 0.021
motor neuron axon guidance GO:0008045 23 0.021
negative regulation of histone methylation GO:0031061 1 0.021
homeostatic process GO:0042592 142 0.021
regulation of nervous system development GO:0051960 90 0.021
lymphocyte homeostasis GO:0002260 1 0.021
regulation of organ growth GO:0046620 3 0.021
defense response GO:0006952 47 0.021
Worm
lymphocyte proliferation GO:0046651 1 0.021
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.020
regulation of binding GO:0051098 3 0.020
trabecula morphogenesis GO:0061383 2 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
cell migration GO:0016477 237 0.020
neural tube development GO:0021915 62 0.020
erythrocyte homeostasis GO:0034101 55 0.020
insulin like growth factor receptor signaling pathway GO:0048009 4 0.020
periodic partitioning GO:0007365 1 0.020
proximal distal pattern formation GO:0009954 1 0.019
skeletal system development GO:0001501 181 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
positive regulation of endothelial cell differentiation GO:0045603 2 0.019
cognition GO:0050890 1 0.019
artery morphogenesis GO:0048844 14 0.019
regeneration GO:0031099 91 0.019
protein secretion GO:0009306 1 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
stem cell division GO:0017145 1 0.019
cell death GO:0008219 121 0.018
Mouse
establishment of epithelial cell polarity GO:0090162 2 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.018
endocardium morphogenesis GO:0003160 4 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
smooth muscle contraction GO:0006939 2 0.018
regulation of proteolysis GO:0030162 24 0.018
stem cell maintenance GO:0019827 4 0.018
habenula development GO:0021986 9 0.018
nerve development GO:0021675 45 0.018
negative regulation of cell communication GO:0010648 96 0.018
signal transduction in absence of ligand GO:0038034 1 0.018
mononuclear cell proliferation GO:0032943 1 0.018
cell projection assembly GO:0030031 64 0.017
heart looping GO:0001947 94 0.017
regulation of blood circulation GO:1903522 32 0.017
aging GO:0007568 2 0.017
Worm
regulation of rna metabolic process GO:0051252 224 0.017
mitotic dna damage checkpoint GO:0044773 4 0.017
oxidation reduction process GO:0055114 41 0.017
action potential GO:0001508 19 0.017
positive regulation of cell cycle GO:0045787 3 0.017
phosphorylation GO:0016310 69 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.016
response to hormone GO:0009725 48 0.016
compound eye development GO:0048749 2 0.016
epithelial cell morphogenesis GO:0003382 2 0.016
cellular response to organic substance GO:0071310 105 0.016
semicircular canal development GO:0060872 24 0.016
regulation of histone methylation GO:0031060 3 0.016
cellular response to oxygen containing compound GO:1901701 20 0.016
positive regulation of catalytic activity GO:0043085 25 0.016

mitfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.337
disease of anatomical entity DOID:7 0 0.337
hematopoietic system disease DOID:74 0 0.126
cancer DOID:162 0 0.058
disease of cellular proliferation DOID:14566 0 0.058
cell type cancer DOID:0050687 0 0.058
gastrointestinal system cancer DOID:3119 0 0.051
organ system cancer DOID:0050686 0 0.051
musculoskeletal system cancer DOID:0060100 0 0.019
reproductive organ cancer DOID:193 0 0.017