Danio rerio

0 known processes

slc1a4

solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

(Aliases: si:zc101n13.5,zgc:92817)

slc1a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.087
cellular component movement GO:0006928 335 0.070
chordate embryonic development GO:0043009 271 0.069
maintenance of location GO:0051235 4 0.065
larval development GO:0002164 2 0.065
central nervous system development GO:0007417 387 0.057
regionalization GO:0003002 274 0.055
negative regulation of cellular process GO:0048523 283 0.054
negative regulation of biological process GO:0048519 304 0.053
response to chemical GO:0042221 320 0.050
lipid storage GO:0019915 1 0.049
positive regulation of catabolic process GO:0009896 4 0.049
cell migration GO:0016477 237 0.047
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.046
head development GO:0060322 303 0.045
alpha amino acid metabolic process GO:1901605 3 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.043
axon ensheathment in central nervous system GO:0032291 2 0.043
regulation of biological quality GO:0065008 263 0.041
specification of symmetry GO:0009799 204 0.041
regulation of signaling GO:0023051 235 0.041
establishment of localization GO:0051234 244 0.040
Human Mouse
neuron differentiation GO:0030182 353 0.039
skeletal system development GO:0001501 181 0.039
mesenchyme development GO:0060485 127 0.038
cell part morphogenesis GO:0032990 246 0.037
regulation of signal transduction GO:0009966 225 0.037
peptide transport GO:0015833 1 0.037
multicellular organismal signaling GO:0035637 22 0.036
generation of neurons GO:0048699 385 0.036
positive regulation of cellular catabolic process GO:0031331 3 0.034
positive regulation of transport GO:0051050 2 0.034
single organism metabolic process GO:0044710 217 0.034
signal transduction GO:0007165 455 0.033
anterior posterior pattern specification GO:0009952 152 0.033
cellular amine metabolic process GO:0044106 2 0.033
negative regulation of response to stimulus GO:0048585 104 0.033
organic substance biosynthetic process GO:1901576 289 0.032
aging GO:0007568 2 0.032
cell fate specification GO:0001708 68 0.032
multicellular organism growth GO:0035264 4 0.031
cell morphogenesis GO:0000902 289 0.031
regulation of macromolecule metabolic process GO:0060255 317 0.030
regulation of cell communication GO:0010646 232 0.029
regulation of stem cell differentiation GO:2000736 4 0.028
transport GO:0006810 220 0.028
Human Mouse
negative regulation of gene expression GO:0010629 65 0.028
immune system process GO:0002376 241 0.028
sensory organ development GO:0007423 393 0.028
central nervous system myelination GO:0022010 2 0.028
amine metabolic process GO:0009308 2 0.027
astrocyte differentiation GO:0048708 1 0.027
heart development GO:0007507 313 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
hormone secretion GO:0046879 2 0.027
meiotic nuclear division GO:0007126 4 0.027
cellular amino acid metabolic process GO:0006520 7 0.026
embryonic organ morphogenesis GO:0048562 274 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.026
determination of bilateral symmetry GO:0009855 204 0.026
cellular macromolecule metabolic process GO:0044260 391 0.026
cellular component morphogenesis GO:0032989 336 0.026
cellular response to external stimulus GO:0071496 2 0.026
regulation of hormone secretion GO:0046883 2 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
determination of left right symmetry GO:0007368 179 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
cell substrate adhesion GO:0031589 4 0.024
neuron development GO:0048666 262 0.024
positive regulation of cell cycle GO:0045787 3 0.023
adult behavior GO:0030534 2 0.023
positive regulation of biological process GO:0048518 253 0.023
organic acid metabolic process GO:0006082 31 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
regulation of response to stimulus GO:0048583 269 0.023
protein metabolic process GO:0019538 183 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
sensory perception of pain GO:0019233 1 0.022
growth GO:0040007 174 0.022
mesenchymal cell differentiation GO:0048762 87 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.021
positive regulation of cellular process GO:0048522 201 0.021
locomotion GO:0040011 313 0.021
ear development GO:0043583 127 0.021
inositol lipid mediated signaling GO:0048017 2 0.021
transmission of nerve impulse GO:0019226 19 0.021
cell fate commitment GO:0045165 99 0.021
localization of cell GO:0051674 244 0.021
vasculature development GO:0001944 278 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
response to stress GO:0006950 263 0.021
inner ear development GO:0048839 126 0.021
regulation of synapse organization GO:0050807 3 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
regulation of blood vessel size GO:0050880 2 0.020
response to monosaccharide GO:0034284 3 0.020
biosynthetic process GO:0009058 294 0.020
response to drug GO:0042493 3 0.020
positive regulation of glial cell differentiation GO:0045687 1 0.020
positive regulation of secretion GO:0051047 1 0.020
action potential GO:0001508 19 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
positive regulation of gtpase activity GO:0043547 1 0.019
transmembrane transport GO:0055085 120 0.019
Human Mouse
response to vitamin GO:0033273 3 0.019
brain development GO:0007420 293 0.019
regulation of cell activation GO:0050865 1 0.019
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
cell motility GO:0048870 244 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
small molecule metabolic process GO:0044281 77 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
carboxylic acid catabolic process GO:0046395 3 0.018
response to external stimulus GO:0009605 264 0.018
oxoacid metabolic process GO:0043436 31 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.018
medulla oblongata development GO:0021550 4 0.018
regulation of cellular component organization GO:0051128 86 0.018
system process GO:0003008 185 0.018
Human
gene expression GO:0010467 252 0.018
regulation of glial cell differentiation GO:0045685 4 0.018
regulation of muscle contraction GO:0006937 3 0.018
cell death GO:0008219 121 0.017
regulation of protein catabolic process GO:0042176 1 0.017
negative regulation of sequestering of calcium ion GO:0051283 4 0.017
neural tube development GO:0021915 62 0.017
intracellular signal transduction GO:0035556 85 0.017
cellular localization GO:0051641 97 0.017
response to organic substance GO:0010033 153 0.017
response to amino acid GO:0043200 2 0.017
positive regulation of jnk cascade GO:0046330 3 0.017
sequestering of metal ion GO:0051238 3 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
response to carbohydrate GO:0009743 3 0.017
camera type eye development GO:0043010 222 0.017
regulation of primary metabolic process GO:0080090 311 0.017
regulation of protein transport GO:0051223 3 0.017
nuclear transport GO:0051169 4 0.017
neuronal action potential GO:0019228 18 0.017
connective tissue development GO:0061448 99 0.017
cell projection organization GO:0030030 284 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
circulatory system process GO:0003013 87 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
negative regulation of metabolic process GO:0009892 86 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
regulation of molecular function GO:0065009 70 0.016
tissue regeneration GO:0042246 74 0.016
regulation of cytokine production GO:0001817 3 0.016
cellular ketone metabolic process GO:0042180 11 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
hormone transport GO:0009914 2 0.016
blood circulation GO:0008015 87 0.016
cytosolic calcium ion transport GO:0060401 3 0.016
phagocytosis GO:0006909 3 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
cellular protein metabolic process GO:0044267 129 0.015
regulation of gtpase activity GO:0043087 2 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
cartilage development GO:0051216 96 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
heart process GO:0003015 71 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
monovalent inorganic cation transport GO:0015672 42 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
response to corticosteroid GO:0031960 1 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
positive regulation of cell activation GO:0050867 1 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
eye morphogenesis GO:0048592 144 0.015
response to hexose GO:0009746 3 0.015
ameboidal type cell migration GO:0001667 143 0.015
protein localization to nucleus GO:0034504 3 0.015
developmental growth GO:0048589 166 0.015
regulation of multicellular organismal metabolic process GO:0044246 2 0.015
skeletal system morphogenesis GO:0048705 102 0.015
axon development GO:0061564 166 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
regulation of inflammatory response GO:0050727 2 0.015
wound healing GO:0042060 90 0.015
response to glucose GO:0009749 3 0.015
transcription dna templated GO:0006351 181 0.015
guanosine containing compound metabolic process GO:1901068 4 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
collagen biosynthetic process GO:0032964 2 0.014
stem cell differentiation GO:0048863 117 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
cell projection morphogenesis GO:0048858 244 0.014
mesenchymal cell development GO:0014031 78 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of binding GO:0051098 3 0.014
organelle organization GO:0006996 227 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
cellular modified amino acid metabolic process GO:0006575 3 0.014
heterocycle metabolic process GO:0046483 290 0.014
negative regulation of defense response GO:0031348 2 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
meiotic cell cycle process GO:1903046 3 0.014
synaptic target recognition GO:0008039 1 0.013
apoptotic process GO:0006915 116 0.013
regulation of reproductive process GO:2000241 4 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
tube morphogenesis GO:0035239 349 0.013
blood vessel development GO:0001568 246 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
gtp catabolic process GO:0006184 2 0.013
sequestering of calcium ion GO:0051208 3 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
positive regulation of blood circulation GO:1903524 2 0.013
protein import GO:0017038 3 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
negative regulation of signaling GO:0023057 96 0.013
cognition GO:0050890 1 0.013
Human
activation of mapk activity GO:0000187 3 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
lateral inhibition GO:0046331 1 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
female sex differentiation GO:0046660 4 0.012
lymphocyte proliferation GO:0046651 1 0.012
single organism nuclear import GO:1902593 3 0.012
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.012
negative regulation of signal transduction GO:0009968 94 0.012
muscle tissue development GO:0060537 110 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
gland development GO:0048732 143 0.012
cellular protein catabolic process GO:0044257 4 0.012
pancreas development GO:0031016 84 0.012
b cell mediated immunity GO:0019724 3 0.012
cardiac muscle tissue development GO:0048738 48 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
centrosome organization GO:0051297 1 0.012
organic acid catabolic process GO:0016054 3 0.012
angiogenesis GO:0001525 158 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
biological adhesion GO:0022610 40 0.012
nuclear import GO:0051170 3 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
gtp metabolic process GO:0046039 4 0.012
mechanosensory behavior GO:0007638 2 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
tissue remodeling GO:0048771 4 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
regulation of cell differentiation GO:0045595 142 0.012
organic substance transport GO:0071702 58 0.012
Human Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
positive regulation of metabolic process GO:0009893 108 0.012
epithelial cell differentiation GO:0030855 116 0.012
axonogenesis GO:0007409 152 0.012
fin regeneration GO:0031101 51 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
small molecule catabolic process GO:0044282 3 0.011
cellular biosynthetic process GO:0044249 286 0.011
regulation of membrane potential GO:0042391 23 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
embryonic skeletal system development GO:0048706 97 0.011
adherens junction organization GO:0034332 4 0.011
multicellular organismal macromolecule metabolic process GO:0044259 2 0.011
regulation of synapse assembly GO:0051963 3 0.011
immune system development GO:0002520 191 0.011
regulation of tube size GO:0035150 2 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
positive regulation of cytokine production GO:0001819 2 0.011
eye development GO:0001654 277 0.011
establishment of localization in cell GO:0051649 77 0.011
digestive system development GO:0055123 289 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
hemopoiesis GO:0030097 183 0.011
cellular response to starvation GO:0009267 1 0.011
embryonic organ development GO:0048568 381 0.011
protein targeting to nucleus GO:0044744 3 0.011
regulation of cell shape GO:0008360 1 0.011
hindbrain development GO:0030902 91 0.011
regeneration GO:0031099 91 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
protein import into nucleus GO:0006606 3 0.011
regulation of cell projection assembly GO:0060491 4 0.011
phosphorylation GO:0016310 69 0.010
stem cell development GO:0048864 82 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
response to alkaloid GO:0043279 2 0.010
canonical wnt signaling pathway GO:0060070 48 0.010
death GO:0016265 121 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
ion transmembrane transport GO:0034220 91 0.010
Human Mouse
regulation of protein binding GO:0043393 3 0.010
heart contraction GO:0060047 71 0.010
neuron projection morphogenesis GO:0048812 161 0.010
regulation of nitrogen compound metabolic process GO:0051171 251 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
digestive tract mesoderm development GO:0007502 1 0.010
negative regulation of ras protein signal transduction GO:0046580 1 0.010

slc1a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.012
cardiovascular system disease DOID:1287 0 0.011
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011
musculoskeletal system disease DOID:17 0 0.010