Danio rerio

66 known processes

LOC100006275

novel protein similar to vertebrate porcupine homolog

LOC100006275 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection morphogenesis GO:0048858 244 0.108
cell surface receptor signaling pathway GO:0007166 325 0.083
cell part morphogenesis GO:0032990 246 0.078
negative regulation of biological process GO:0048519 304 0.064
synaptic growth at neuromuscular junction GO:0051124 2 0.064
generation of neurons GO:0048699 385 0.061
regulation of response to stimulus GO:0048583 269 0.060
neuron development GO:0048666 262 0.057
regulation of signaling GO:0023051 235 0.056
cell morphogenesis GO:0000902 289 0.051
neuron projection morphogenesis GO:0048812 161 0.049
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.048
regulation of reproductive process GO:2000241 4 0.048
cell projection organization GO:0030030 284 0.047
cognition GO:0050890 1 0.045
larval development GO:0002164 2 0.044
neuron projection development GO:0031175 180 0.043
cellular component morphogenesis GO:0032989 336 0.042
neuron differentiation GO:0030182 353 0.041
regulation of multicellular organismal process GO:0051239 277 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
regulation of synapse organization GO:0050807 3 0.040
locomotion GO:0040011 313 0.039
cellular component movement GO:0006928 335 0.038
specification of symmetry GO:0009799 204 0.038
aging GO:0007568 2 0.038
digestive system development GO:0055123 289 0.038
morphogenesis of an epithelium GO:0002009 333 0.037
regulation of cell communication GO:0010646 232 0.037
determination of bilateral symmetry GO:0009855 204 0.036
regulation of signal transduction GO:0009966 225 0.033
regulation of nervous system development GO:0051960 90 0.033
multi organism process GO:0051704 134 0.032
signal transduction GO:0007165 455 0.032
cellular nitrogen compound metabolic process GO:0034641 290 0.032
digestive tract morphogenesis GO:0048546 231 0.032
response to wounding GO:0009611 116 0.032
heart development GO:0007507 313 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.031
gastrulation GO:0007369 208 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
response to carbohydrate GO:0009743 3 0.030
regulation of cell projection assembly GO:0060491 4 0.030
regulation of synapse assembly GO:0051963 3 0.030
growth GO:0040007 174 0.030
positive regulation of transport GO:0051050 2 0.029
leukocyte proliferation GO:0070661 1 0.029
cellular response to external stimulus GO:0071496 2 0.029
retina development in camera type eye GO:0060041 146 0.029
cell morphogenesis involved in differentiation GO:0000904 195 0.028
regulation of reactive oxygen species metabolic process GO:2000377 2 0.027
regulation of cell activation GO:0050865 1 0.027
regulation of cellular metabolic process GO:0031323 320 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
response to external stimulus GO:0009605 264 0.027
tube morphogenesis GO:0035239 349 0.026
fertilization GO:0009566 3 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.024
enzyme linked receptor protein signaling pathway GO:0007167 106 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
immune system process GO:0002376 241 0.024
heterocycle metabolic process GO:0046483 290 0.023
chemotaxis GO:0006935 104 0.023
single organism organelle organization GO:1902589 199 0.023
negative regulation of protein transport GO:0051224 3 0.023
regulation of developmental process GO:0050793 247 0.023
guanosine containing compound metabolic process GO:1901068 4 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
muscle structure development GO:0061061 196 0.022
eye development GO:0001654 277 0.022
positive regulation of cellular process GO:0048522 201 0.022
cell motility GO:0048870 244 0.022
negative regulation of cellular process GO:0048523 283 0.022
meiotic nuclear division GO:0007126 4 0.022
axon guidance GO:0007411 86 0.022
cellular amine metabolic process GO:0044106 2 0.022
central nervous system development GO:0007417 387 0.021
phosphorus metabolic process GO:0006793 109 0.021
axonogenesis GO:0007409 152 0.021
peptidyl threonine phosphorylation GO:0018107 1 0.021
protein metabolic process GO:0019538 183 0.021
stem cell maintenance GO:0019827 4 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
axon development GO:0061564 166 0.021
chordate embryonic development GO:0043009 271 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of protein complex assembly GO:0043254 3 0.021
developmental growth GO:0048589 166 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
negative regulation of cell communication GO:0010648 96 0.020
organelle organization GO:0006996 227 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
peptide metabolic process GO:0006518 1 0.020
nuclear import GO:0051170 3 0.020
determination of left right symmetry GO:0007368 179 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
digestive tract development GO:0048565 265 0.020
regulation of gene expression GO:0010468 265 0.020
brain development GO:0007420 293 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
multicellular organismal metabolic process GO:0044236 2 0.020
transcription dna templated GO:0006351 181 0.020
modification dependent protein catabolic process GO:0019941 3 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
regulation of protein transport GO:0051223 3 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
amino acid transport GO:0006865 2 0.019
urogenital system development GO:0001655 97 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
cellular response to organic substance GO:0071310 105 0.019
positive regulation of catabolic process GO:0009896 4 0.019
rna metabolic process GO:0016070 219 0.019
cell migration GO:0016477 237 0.019
cellular ketone metabolic process GO:0042180 11 0.019
protein import GO:0017038 3 0.018
cellular amide metabolic process GO:0043603 4 0.018
cellular component assembly GO:0022607 170 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
protein targeting to nucleus GO:0044744 3 0.018
positive regulation of cell activation GO:0050867 1 0.018
negative regulation of signal transduction GO:0009968 94 0.018
g protein coupled receptor signaling pathway GO:0007186 74 0.018
amine metabolic process GO:0009308 2 0.018
phagocytosis GO:0006909 3 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
negative regulation of signaling GO:0023057 96 0.018
response to organic substance GO:0010033 153 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.017
single organism metabolic process GO:0044710 217 0.017
peptide transport GO:0015833 1 0.017
regulation of cytokine production GO:0001817 3 0.017
protein polymerization GO:0051258 4 0.017
response to glucose GO:0009749 3 0.017
exocytosis GO:0006887 1 0.017
cell death GO:0008219 121 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
gtp catabolic process GO:0006184 2 0.017
response to stress GO:0006950 263 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
peptidyl threonine modification GO:0018210 1 0.017
response to hexose GO:0009746 3 0.017
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
stem cell proliferation GO:0072089 4 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of protein catabolic process GO:0042176 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
positive regulation of cell killing GO:0031343 2 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
regulation of primary metabolic process GO:0080090 311 0.016
cellular component disassembly GO:0022411 1 0.016
carbohydrate homeostasis GO:0033500 1 0.016
regulation of blood pressure GO:0008217 1 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
small molecule catabolic process GO:0044282 3 0.016
endocrine process GO:0050886 2 0.016
regulation of protein polymerization GO:0032271 2 0.016
regulation of microtubule cytoskeleton organization GO:0070507 3 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of tube size GO:0035150 2 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
gtp metabolic process GO:0046039 4 0.016
regulation of metabolic process GO:0019222 359 0.015
maintenance of location GO:0051235 4 0.015
primary neural tube formation GO:0014020 1 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
microtubule based process GO:0007017 60 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
dicarboxylic acid transport GO:0006835 1 0.015
protein secretion GO:0009306 1 0.015
neurotransmitter transport GO:0006836 2 0.015
mitochondrion organization GO:0007005 4 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
positive regulation of immune effector process GO:0002699 3 0.015
positive regulation of biological process GO:0048518 253 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
convergent extension GO:0060026 118 0.015
negative regulation of kinase activity GO:0033673 4 0.015
meiotic cell cycle process GO:1903046 3 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
single organism nuclear import GO:1902593 3 0.015
single fertilization GO:0007338 3 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
nuclear transport GO:0051169 4 0.014
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
regulation of blood vessel size GO:0050880 2 0.014
organic acid metabolic process GO:0006082 31 0.014
regulation of biological quality GO:0065008 263 0.014
multicellular organism growth GO:0035264 4 0.014
superoxide metabolic process GO:0006801 2 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
regulation of binding GO:0051098 3 0.014
glucose homeostasis GO:0042593 1 0.014
response to chemical GO:0042221 320 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
small molecule metabolic process GO:0044281 77 0.014
protein localization to nucleus GO:0034504 3 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
response to monosaccharide GO:0034284 3 0.014
oxoacid metabolic process GO:0043436 31 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
centrosome organization GO:0051297 1 0.014
protein import into nucleus GO:0006606 3 0.013
regulation of glial cell differentiation GO:0045685 4 0.013
macromolecule modification GO:0043412 111 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
bmp signaling pathway GO:0030509 52 0.013
female gonad development GO:0008585 4 0.013
mesenchyme development GO:0060485 127 0.013
anterior posterior pattern specification GO:0009952 152 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.013
gene expression GO:0010467 252 0.013
membrane invagination GO:0010324 1 0.013
response to uv GO:0009411 3 0.013
adult behavior GO:0030534 2 0.013
synaptic vesicle transport GO:0048489 1 0.013
multicellular organismal response to stress GO:0033555 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
autophagy GO:0006914 4 0.013
lateral inhibition GO:0046331 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
sensory perception of pain GO:0019233 1 0.013
positive regulation of cytokine production GO:0001819 2 0.012
protein dephosphorylation GO:0006470 3 0.012
taxis GO:0042330 109 0.012
b cell activation GO:0042113 2 0.012
positive regulation of cell cycle GO:0045787 3 0.012
organelle assembly GO:0070925 110 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of protein binding GO:0043393 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
regulation of exocytosis GO:0017157 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
cellular protein catabolic process GO:0044257 4 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
system process GO:0003008 185 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
endosomal transport GO:0016197 2 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
meiotic chromosome segregation GO:0045132 3 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
protein stabilization GO:0050821 2 0.012
regionalization GO:0003002 274 0.012
death GO:0016265 121 0.012
cell killing GO:0001906 2 0.012
regulation of neurological system process GO:0031644 2 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
regulation of gtpase activity GO:0043087 2 0.012
protein complex disassembly GO:0043241 1 0.011
response to endogenous stimulus GO:0009719 83 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
interspecies interaction between organisms GO:0044419 4 0.011
neurotransmitter secretion GO:0007269 2 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
homeostatic process GO:0042592 142 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
cellular biosynthetic process GO:0044249 286 0.011
post embryonic organ development GO:0048569 4 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
regulation of filopodium assembly GO:0051489 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
tissue remodeling GO:0048771 4 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
establishment of localization GO:0051234 244 0.011
regulation of hormone secretion GO:0046883 2 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
defense response GO:0006952 47 0.011
regulation of protein targeting GO:1903533 2 0.011
regulation of endocrine process GO:0044060 2 0.011
response to biotic stimulus GO:0009607 97 0.011
protein modification process GO:0036211 100 0.011
striated muscle cell development GO:0055002 108 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
positive regulation of multi organism process GO:0043902 3 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of response to biotic stimulus GO:0002831 2 0.010
phagocytosis engulfment GO:0006911 1 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
hormone secretion GO:0046879 2 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
response to other organism GO:0051707 97 0.010
motor neuron axon guidance GO:0008045 23 0.010
regulation of metal ion transport GO:0010959 4 0.010
localization of cell GO:0051674 244 0.010
neuron projection guidance GO:0097485 86 0.010
negative regulation of cytokine production GO:0001818 1 0.010
spindle assembly GO:0051225 2 0.010
gland development GO:0048732 143 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
synaptic vesicle localization GO:0097479 1 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
protein acylation GO:0043543 3 0.010

LOC100006275 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
disease of metabolism DOID:0014667 0 0.017
immune system disease DOID:2914 0 0.014
nervous system disease DOID:863 0 0.013
musculoskeletal system disease DOID:17 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011