Danio rerio

76 known processes

sox21a

SRY-box containing gene 21a

(Aliases: sox21,sox30,sox25,SRY-box)

sox21a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 213 0.855
glycoprotein biosynthetic process GO:0009101 21 0.855
regulation of metabolic process GO:0019222 359 0.842
organic substance biosynthetic process GO:1901576 289 0.836
nucleobase containing compound biosynthetic process GO:0034654 205 0.776
cellular macromolecule biosynthetic process GO:0034645 224 0.773
nucleic acid metabolic process GO:0090304 244 0.760
cellular biosynthetic process GO:0044249 286 0.711
cell part morphogenesis GO:0032990 246 0.682
biosynthetic process GO:0009058 294 0.672
regulation of cellular metabolic process GO:0031323 320 0.661
cellular macromolecule metabolic process GO:0044260 391 0.645
cellular aromatic compound metabolic process GO:0006725 295 0.643
regulation of gene expression GO:0010468 265 0.618
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.617
nitrogen compound metabolic process GO:0006807 319 0.617
cell morphogenesis involved in differentiation GO:0000904 195 0.616
sensory system development GO:0048880 76 0.615
glycoprotein metabolic process GO:0009100 23 0.578
regulation of rna biosynthetic process GO:2001141 213 0.550
regulation of biosynthetic process GO:0009889 250 0.529
nucleobase containing compound metabolic process GO:0006139 274 0.505
macromolecule biosynthetic process GO:0009059 227 0.502
endodermal cell fate determination GO:0007493 2 0.488
regulation of macromolecule metabolic process GO:0060255 317 0.468
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.465
response to chemical GO:0042221 320 0.450
heterocycle biosynthetic process GO:0018130 215 0.442
regulation of macromolecule biosynthetic process GO:0010556 225 0.427
heterocycle metabolic process GO:0046483 290 0.415
neuron development GO:0048666 262 0.404
embryonic organ development GO:0048568 381 0.399
single organism localization GO:1902578 225 0.396
aromatic compound biosynthetic process GO:0019438 217 0.370
cellular component movement GO:0006928 335 0.368
organic cyclic compound biosynthetic process GO:1901362 223 0.364
larval development GO:0002164 2 0.358
cell projection morphogenesis GO:0048858 244 0.348
organic cyclic compound metabolic process GO:1901360 301 0.333
regionalization GO:0003002 274 0.332
nephron morphogenesis GO:0072028 2 0.329
cellular nitrogen compound metabolic process GO:0034641 290 0.324
axonogenesis GO:0007409 152 0.321
regulation of rna metabolic process GO:0051252 224 0.320
digestive tract morphogenesis GO:0048546 231 0.318
positive regulation of metabolic process GO:0009893 108 0.310
heart looping GO:0001947 94 0.309
brain development GO:0007420 293 0.302
transcription dna templated GO:0006351 181 0.295
gene expression GO:0010467 252 0.294
regulation of primary metabolic process GO:0080090 311 0.288
sensory organ morphogenesis GO:0090596 200 0.280
digestive system development GO:0055123 289 0.276
negative regulation of gene expression GO:0010629 65 0.274
neuroblast differentiation GO:0014016 1 0.263
regulation of nitrogen compound metabolic process GO:0051171 251 0.257
negative regulation of cellular process GO:0048523 283 0.256
determination of heart left right asymmetry GO:0061371 117 0.252
epithelial cell differentiation GO:0030855 116 0.249
ion transmembrane transport GO:0034220 91 0.247
regulation of cellular biosynthetic process GO:0031326 245 0.242
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.241
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.238
sensory organ development GO:0007423 393 0.237
Zebrafish
glycolipid biosynthetic process GO:0009247 1 0.225
ear morphogenesis GO:0042471 64 0.221
neuron projection morphogenesis GO:0048812 161 0.219
immune system process GO:0002376 241 0.204
negative regulation of macromolecule metabolic process GO:0010605 76 0.203
establishment of localization GO:0051234 244 0.200
nucleic acid templated transcription GO:0097659 181 0.189
dorsal ventral pattern formation GO:0009953 125 0.188
regulation of transcription dna templated GO:0006355 213 0.186
posterior lateral line system development GO:0048915 46 0.185
central nervous system development GO:0007417 387 0.181
nephron tubule morphogenesis GO:0072078 1 0.176
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.172
digestive tract development GO:0048565 265 0.167
cell surface receptor signaling pathway GO:0007166 325 0.164
positive regulation of transcription dna templated GO:0045893 57 0.163
neuron differentiation GO:0030182 353 0.163
regulation of multicellular organismal process GO:0051239 277 0.162
specification of symmetry GO:0009799 204 0.154
cilium assembly GO:0042384 58 0.153
rna biosynthetic process GO:0032774 181 0.148
positive regulation of rna biosynthetic process GO:1902680 57 0.146
mechanosensory lateral line system development GO:0048881 49 0.144
cell fate specification GO:0001708 68 0.143
locomotion GO:0040011 313 0.137
carbohydrate derivative biosynthetic process GO:1901137 43 0.135
chordate embryonic development GO:0043009 271 0.133
cellular nitrogen compound biosynthetic process GO:0044271 218 0.131
negative regulation of transcription dna templated GO:0045892 45 0.123
ear development GO:0043583 127 0.121
transport GO:0006810 220 0.121
negative regulation of cellular biosynthetic process GO:0031327 55 0.118
positive regulation of macromolecule metabolic process GO:0010604 93 0.117
endocrine pancreas development GO:0031018 27 0.117
generation of neurons GO:0048699 385 0.116
response to external stimulus GO:0009605 264 0.116
embryonic organ morphogenesis GO:0048562 274 0.114
gastrulation GO:0007369 208 0.113
pancreas development GO:0031016 84 0.113
regulation of inner ear receptor cell differentiation GO:2000980 1 0.111
positive regulation of cellular metabolic process GO:0031325 94 0.111
cilium morphogenesis GO:0060271 85 0.111
protein metabolic process GO:0019538 183 0.110
negative regulation of protein localization to nucleus GO:1900181 2 0.109
renal tubule morphogenesis GO:0061333 1 0.107
positive regulation of stem cell proliferation GO:2000648 1 0.106
negative regulation of multicellular organismal process GO:0051241 69 0.104
cell morphogenesis GO:0000902 289 0.103
secondary metabolic process GO:0019748 3 0.103
cellular component morphogenesis GO:0032989 336 0.102
negative regulation of nervous system development GO:0051961 22 0.102
skeletal system development GO:0001501 181 0.101
ceramide biosynthetic process GO:0046513 1 0.097
regulation of cardiac muscle tissue development GO:0055024 1 0.097
phosphorus metabolic process GO:0006793 109 0.096
single organism transport GO:0044765 206 0.096
mesodermal cell fate commitment GO:0001710 14 0.096
lipid storage GO:0019915 1 0.094
lateral line system development GO:0048925 76 0.094
negative regulation of rna metabolic process GO:0051253 48 0.094
nephron epithelium morphogenesis GO:0072088 1 0.092
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.092
embryonic heart tube development GO:0035050 133 0.091
negative regulation of metabolic process GO:0009892 86 0.090
cilium organization GO:0044782 71 0.088
negative regulation of biological process GO:0048519 304 0.087
regulation of cell differentiation GO:0045595 142 0.086
positive regulation of biosynthetic process GO:0009891 68 0.086
signal transduction GO:0007165 455 0.085
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.084
equilibrioception GO:0050957 2 0.083
neuron projection development GO:0031175 180 0.082
inner ear development GO:0048839 126 0.081
determination of bilateral symmetry GO:0009855 204 0.081
muscle cell migration GO:0014812 4 0.080
dna templated transcription initiation GO:0006352 1 0.079
response to abiotic stimulus GO:0009628 122 0.078
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.077
negative regulation of cellular metabolic process GO:0031324 77 0.077
determination of left right symmetry GO:0007368 179 0.075
organic acid metabolic process GO:0006082 31 0.075
adult behavior GO:0030534 2 0.074
striated muscle cell differentiation GO:0051146 129 0.071
aging GO:0007568 2 0.070
morphogenesis of an epithelium GO:0002009 333 0.068
regulation of multicellular organismal development GO:2000026 223 0.068
proximal distal pattern formation GO:0009954 1 0.067
protein localization to nucleus GO:0034504 3 0.067
negative regulation of nucleic acid templated transcription GO:1903507 45 0.066
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.064
eye development GO:0001654 277 0.061
Zebrafish
neuron projection guidance GO:0097485 86 0.060
positive regulation of cellular process GO:0048522 201 0.060
stem cell proliferation GO:0072089 4 0.059
positive regulation of cellular biosynthetic process GO:0031328 68 0.059
chemotaxis GO:0006935 104 0.058
inner ear morphogenesis GO:0042472 63 0.058
neuroblast fate commitment GO:0014017 1 0.058
stem cell fate commitment GO:0048865 1 0.057
positive regulation of epithelial cell differentiation GO:0030858 2 0.057
regulation of developmental process GO:0050793 247 0.056
single organism metabolic process GO:0044710 217 0.056
transcription from rna polymerase ii promoter GO:0006366 80 0.055
neuron fate determination GO:0048664 2 0.054
posterior lateral line neuromast development GO:0048919 20 0.053
otic vesicle morphogenesis GO:0071600 34 0.053
peripheral nervous system development GO:0007422 55 0.053
membrane lipid biosynthetic process GO:0046467 2 0.053
heart morphogenesis GO:0003007 156 0.052
system process GO:0003008 185 0.052
regulation of nucleocytoplasmic transport GO:0046822 2 0.052
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.052
regulation of protein import into nucleus GO:0042306 2 0.052
carbohydrate derivative metabolic process GO:1901135 61 0.052
head development GO:0060322 303 0.051
positive regulation of nucleoside metabolic process GO:0045979 1 0.051
rna metabolic process GO:0016070 219 0.050
positive regulation of nucleic acid templated transcription GO:1903508 57 0.050
protein glycosylation GO:0006486 9 0.049
lateral line development GO:0048882 66 0.049
phosphate containing compound metabolic process GO:0006796 108 0.048
regulation of binding GO:0051098 3 0.048
glucose homeostasis GO:0042593 1 0.047
protein import GO:0017038 3 0.047
hepaticobiliary system development GO:0061008 98 0.046
establishment of protein localization to organelle GO:0072594 4 0.046
diencephalon development GO:0021536 58 0.045
response to drug GO:0042493 3 0.045
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.045
regulation of neuron differentiation GO:0045664 56 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.044
single organism nuclear import GO:1902593 3 0.043
response to stress GO:0006950 263 0.043
oocyte maturation GO:0001556 4 0.043
response to biotic stimulus GO:0009607 97 0.043
protein processing GO:0016485 12 0.043
maintenance of location GO:0051235 4 0.042
neuromast development GO:0048884 46 0.042
multi organism process GO:0051704 134 0.041
regulation of multicellular organism growth GO:0040014 4 0.041
cellular response to extracellular stimulus GO:0031668 2 0.041
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.039
muscle fiber development GO:0048747 52 0.039
olfactory placode formation GO:0030910 1 0.039
positive regulation of transport GO:0051050 2 0.039
positive regulation of nucleotide catabolic process GO:0030813 1 0.039
glial cell differentiation GO:0010001 42 0.038
astrocyte differentiation GO:0048708 1 0.038
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.038
positive regulation of catabolic process GO:0009896 4 0.038
protein import into nucleus GO:0006606 3 0.038
reproduction GO:0000003 40 0.037
cell proliferation in forebrain GO:0021846 3 0.037
muscle organ development GO:0007517 101 0.036
type i interferon production GO:0032606 2 0.036
embryonic heart tube morphogenesis GO:0003143 108 0.036
morphogenesis of a branching epithelium GO:0061138 16 0.036
notch signaling pathway GO:0007219 35 0.036
anterior posterior pattern specification GO:0009952 152 0.036
otic placode formation GO:0043049 23 0.036
regulation of intracellular protein transport GO:0033157 3 0.035
negative regulation of reproductive process GO:2000242 3 0.035
organelle localization GO:0051640 49 0.035
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.035
cellular response to organic substance GO:0071310 105 0.035
regulation of anatomical structure morphogenesis GO:0022603 130 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
branching morphogenesis of an epithelial tube GO:0048754 15 0.034
regulation of protein localization to nucleus GO:1900180 2 0.034
regulation of dna replication GO:0006275 3 0.034
glycosphingolipid biosynthetic process GO:0006688 1 0.034
cellular response to chemical stimulus GO:0070887 157 0.033
ceramide metabolic process GO:0006672 5 0.033
regulation of molecular function GO:0065009 70 0.033
primitive hemopoiesis GO:0060215 27 0.033
nuclear transport GO:0051169 4 0.033
regulation of carbohydrate metabolic process GO:0006109 4 0.033
hematopoietic or lymphoid organ development GO:0048534 191 0.033
defense response GO:0006952 47 0.032
regulation of catalytic activity GO:0050790 55 0.032
peripheral nervous system neuron differentiation GO:0048934 28 0.032
g2 m transition of mitotic cell cycle GO:0000086 4 0.032
endoderm development GO:0007492 49 0.032
endocrine system development GO:0035270 65 0.032
embryonic skeletal system development GO:0048706 97 0.032
axon guidance GO:0007411 86 0.032
negative regulation of signal transduction GO:0009968 94 0.032
positive regulation of jun kinase activity GO:0043507 2 0.031
tissue regeneration GO:0042246 74 0.031
neuroblast proliferation GO:0007405 2 0.031
muscle tissue development GO:0060537 110 0.031
regulation of cell communication GO:0010646 232 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.030
positive regulation of biological process GO:0048518 253 0.030
regulation of organ growth GO:0046620 3 0.030
neural plate pattern specification GO:0060896 12 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.029
ectodermal placode development GO:0071696 37 0.029
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.029
heart process GO:0003015 71 0.029
cell migration GO:0016477 237 0.029
female sex differentiation GO:0046660 4 0.029
negative regulation of neuron projection regeneration GO:0070571 4 0.028
positive regulation of rna metabolic process GO:0051254 59 0.028
chromosome organization GO:0051276 31 0.028
negative regulation of response to stimulus GO:0048585 104 0.028
cellular response to external stimulus GO:0071496 2 0.028
posterior lateral line neuromast deposition GO:0048922 5 0.028
negative regulation of smoothened signaling pathway GO:0045879 6 0.028
organelle organization GO:0006996 227 0.028
positive regulation of dna metabolic process GO:0051054 1 0.028
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.028
epithelial tube morphogenesis GO:0060562 148 0.028
cellular protein modification process GO:0006464 100 0.028
wound healing GO:0042060 90 0.027
central nervous system neuron differentiation GO:0021953 74 0.027
response to monosaccharide GO:0034284 3 0.027
striated muscle tissue development GO:0014706 110 0.027
renal system development GO:0072001 94 0.027
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.027
cell motility GO:0048870 244 0.027
heart development GO:0007507 313 0.027
growth GO:0040007 174 0.027
b cell activation GO:0042113 2 0.026
regulation of cellular protein metabolic process GO:0032268 52 0.026
negative regulation of protein complex assembly GO:0031333 1 0.026
cellular response to nutrient levels GO:0031669 2 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.026
epidermis morphogenesis GO:0048730 4 0.026
epithelial cell development GO:0002064 42 0.025
central nervous system myelin formation GO:0032289 1 0.025
mesenchyme development GO:0060485 127 0.025
patterning of blood vessels GO:0001569 15 0.025
macromolecule localization GO:0033036 54 0.025
negative regulation of axon regeneration GO:0048681 4 0.024
small molecule metabolic process GO:0044281 77 0.024
endothelial cell differentiation GO:0045446 20 0.024
cellular component biogenesis GO:0044085 178 0.024
regulation of dna metabolic process GO:0051052 11 0.024
regulation of nervous system development GO:0051960 90 0.024
homeostatic process GO:0042592 142 0.024
cell projection organization GO:0030030 284 0.024
developmental programmed cell death GO:0010623 4 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
striated muscle cell development GO:0055002 108 0.023
otolith development GO:0048840 32 0.023
negative regulation of cell development GO:0010721 26 0.023
cerebellar cortex morphogenesis GO:0021696 5 0.023
response to carbohydrate GO:0009743 3 0.023
embryonic skeletal system morphogenesis GO:0048704 93 0.022
posterior lateral line development GO:0048916 38 0.022
negative regulation of biosynthetic process GO:0009890 55 0.022
optic placode formation involved in camera type eye formation GO:0046619 3 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
phosphorylation GO:0016310 69 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.021
protein modification process GO:0036211 100 0.021
endothelium development GO:0003158 25 0.021
regulation of epithelial to mesenchymal transition GO:0010717 3 0.021
regulation of isoprenoid metabolic process GO:0019747 6 0.020
negative regulation of cytoplasmic transport GO:1903650 2 0.020
regulation of signal transduction GO:0009966 225 0.020
apoptotic signaling pathway GO:0097190 23 0.020
negative regulation of intracellular protein transport GO:0090317 3 0.020
ectodermal placode formation GO:0060788 26 0.020
regulation of cell development GO:0060284 100 0.020
macromolecule modification GO:0043412 111 0.020
sensory neuron axon guidance GO:0097374 3 0.020
regulation of stem cell proliferation GO:0072091 2 0.020
synaptic transmission GO:0007268 35 0.020
forebrain generation of neurons GO:0021872 14 0.020
epidermal cell fate specification GO:0009957 4 0.020
glial cell fate specification GO:0021780 4 0.020
axon development GO:0061564 166 0.019
chemical homeostasis GO:0048878 49 0.019
brain segmentation GO:0035284 6 0.019
negative regulation of intracellular transport GO:0032387 3 0.019
wnt signaling pathway GO:0016055 80 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
regulation of protein metabolic process GO:0051246 56 0.019
metencephalon development GO:0022037 27 0.019
regulation of cell cycle GO:0051726 52 0.019
positive regulation of cell cycle GO:0045787 3 0.019
mechanoreceptor differentiation GO:0042490 37 0.019
single organism carbohydrate metabolic process GO:0044723 12 0.019
determination of pancreatic left right asymmetry GO:0035469 11 0.019
oligodendrocyte differentiation GO:0048709 23 0.018
regulation of protein complex assembly GO:0043254 3 0.018
single organism biosynthetic process GO:0044711 71 0.018
protein targeting to nucleus GO:0044744 3 0.018
hindbrain morphogenesis GO:0021575 22 0.018
locomotory behavior GO:0007626 34 0.018
mesodermal cell differentiation GO:0048333 21 0.018
cytokinesis GO:0000910 3 0.018
otic vesicle development GO:0071599 42 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
dorsal ventral axis specification GO:0009950 14 0.018
gland development GO:0048732 143 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
regulation of protein targeting GO:1903533 2 0.017
camera type eye development GO:0043010 222 0.017
Zebrafish
glycosylation GO:0070085 11 0.017
regulation of cell fate specification GO:0042659 20 0.017
cellular lipid metabolic process GO:0044255 36 0.017
response to external biotic stimulus GO:0043207 97 0.017
response to lipid GO:0033993 60 0.017
appendage morphogenesis GO:0035107 56 0.017
pectoral fin development GO:0033339 50 0.017
regulation of jun kinase activity GO:0043506 3 0.017
pectoral fin morphogenesis GO:0035138 29 0.017
kidney development GO:0001822 92 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
regulation of biological quality GO:0065008 263 0.017
single organism behavior GO:0044708 24 0.016
forebrain anterior posterior pattern specification GO:0021797 3 0.016
single organism organelle organization GO:1902589 199 0.016
regulation of protein binding GO:0043393 3 0.016
regulation of gastrulation GO:0010470 24 0.016
response to bacterium GO:0009617 58 0.016
hemopoiesis GO:0030097 183 0.016
negative regulation of collateral sprouting GO:0048671 2 0.016
negative regulation of mitosis GO:0045839 3 0.016
radial glial cell differentiation GO:0060019 2 0.016
apoptotic process involved in morphogenesis GO:0060561 2 0.016
sphingolipid biosynthetic process GO:0030148 2 0.016
oxoacid metabolic process GO:0043436 31 0.016
innate immune response GO:0045087 13 0.016
endodermal cell fate commitment GO:0001711 18 0.016
negative regulation of signaling GO:0023057 96 0.016
regulation of response to stimulus GO:0048583 269 0.016
regulation of circadian rhythm GO:0042752 4 0.016
positive regulation of notch signaling pathway GO:0045747 3 0.016
lipid metabolic process GO:0006629 52 0.016
otic vesicle formation GO:0030916 27 0.016
muscle cell development GO:0055001 115 0.015
gliogenesis GO:0042063 45 0.015
myotube differentiation GO:0014902 45 0.015
apoptotic process GO:0006915 116 0.015
retinal cell programmed cell death GO:0046666 2 0.015
chromatin organization GO:0006325 22 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
embryonic viscerocranium morphogenesis GO:0048703 52 0.015
insulin like growth factor receptor signaling pathway GO:0048009 4 0.015
positive regulation of phospholipase c activity GO:0010863 1 0.015
intestinal epithelial structure maintenance GO:0060729 7 0.015
axis specification GO:0009798 43 0.015
forebrain cell migration GO:0021885 1 0.015
canonical wnt signaling pathway GO:0060070 48 0.015
kidney morphogenesis GO:0060993 15 0.015
ventral spinal cord interneuron fate commitment GO:0060579 3 0.015
organic substance transport GO:0071702 58 0.015
regulation of heart growth GO:0060420 2 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
interaction with host GO:0051701 4 0.015
morphogenesis of a branching structure GO:0001763 21 0.014
fin development GO:0033333 77 0.014
protein maturation GO:0051604 12 0.014
dna metabolic process GO:0006259 27 0.014
endoderm formation GO:0001706 29 0.014
negative regulation of nuclear division GO:0051784 3 0.014
regulation of signaling GO:0023051 235 0.014
negative regulation of neural precursor cell proliferation GO:2000178 1 0.014
regulation of autophagy GO:0010506 3 0.014
nuclear import GO:0051170 3 0.014
regulation of transport GO:0051049 45 0.014
appendage development GO:0048736 80 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
developmental maturation GO:0021700 34 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
response to uv GO:0009411 3 0.014
negative regulation of molecular function GO:0044092 23 0.014
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.014
mitochondrion organization GO:0007005 4 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
regulation of endodermal cell differentiation GO:1903224 15 0.014
single organism membrane organization GO:0044802 20 0.014
formation of primary germ layer GO:0001704 62 0.014
skeletal muscle tissue development GO:0007519 67 0.013
regulation of mesenchymal cell proliferation GO:0010464 1 0.013
determination of dorsal ventral asymmetry GO:0048262 34 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
regulation of endodermal cell fate specification GO:0042663 15 0.013
gastrulation with mouth forming second GO:0001702 44 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
iron ion homeostasis GO:0055072 4 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
stem cell differentiation GO:0048863 117 0.013
cellular localization GO:0051641 97 0.013
commissural neuron axon guidance GO:0071679 3 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
embryonic neurocranium morphogenesis GO:0048702 15 0.013
eye morphogenesis GO:0048592 144 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.013
pigment cell differentiation GO:0050931 38 0.013
regulation of mechanoreceptor differentiation GO:0045631 1 0.013
response to organic substance GO:0010033 153 0.012
positive regulation of muscle tissue development GO:1901863 1 0.012
ventral spinal cord interneuron specification GO:0021521 3 0.012
negative regulation of neurogenesis GO:0050768 20 0.012
cellular ketone metabolic process GO:0042180 11 0.012
macroautophagy GO:0016236 1 0.012
fin morphogenesis GO:0033334 53 0.012
lipid biosynthetic process GO:0008610 22 0.012
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.012
regulation of synapse organization GO:0050807 3 0.012
circulatory system process GO:0003013 87 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
mesodermal cell fate specification GO:0007501 12 0.012
embryonic digestive tract morphogenesis GO:0048557 3 0.012
negative regulation of catabolic process GO:0009895 3 0.012
forebrain morphogenesis GO:0048853 6 0.012
cell proliferation in midbrain GO:0033278 4 0.012
regulation of protein transport GO:0051223 3 0.012
oligodendrocyte cell fate specification GO:0021778 4 0.012
central nervous system neuron development GO:0021954 29 0.011
death GO:0016265 121 0.011
tongue morphogenesis GO:0043587 3 0.011

sox21a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.101
disease of cellular proliferation DOID:14566 0 0.101
organ system cancer DOID:0050686 0 0.101
disease of anatomical entity DOID:7 0 0.056
large intestine cancer DOID:5672 0 0.027
colon cancer DOID:219 0 0.027
gastrointestinal system cancer DOID:3119 0 0.027
intestinal cancer DOID:10155 0 0.027
colorectal cancer DOID:9256 0 0.027
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.018
microphthalmia DOID:10629 0 0.018
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
colon carcinoma DOID:1520 0 0.015