Danio rerio

7 known processes

pgk1

phosphoglycerate kinase 1

(Aliases: wu:fj36g06,wu:fd59b07,zgc:56252,zgc:77899)

pgk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myosin filament assembly GO:0031034 6 0.434
pyruvate metabolic process GO:0006090 1 0.312
actomyosin structure organization GO:0031032 53 0.311
organelle assembly GO:0070925 110 0.226
myosin filament organization GO:0031033 6 0.193
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.167
striated muscle myosin thick filament assembly GO:0071688 6 0.165
aging GO:0007568 2 0.147
carbohydrate biosynthetic process GO:0016051 1 0.143
lateral inhibition GO:0046331 1 0.142
larval development GO:0002164 2 0.135
single organism metabolic process GO:0044710 217 0.134
cellular component assembly involved in morphogenesis GO:0010927 107 0.130
embryo development ending in birth or egg hatching GO:0009792 271 0.128
actin filament based process GO:0030029 64 0.126
somatic muscle development GO:0007525 4 0.124
striated muscle cell development GO:0055002 108 0.093
muscle cell differentiation GO:0042692 139 0.090
single organism carbohydrate metabolic process GO:0044723 12 0.085
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.077
organelle fusion GO:0048284 3 0.077
cellular aldehyde metabolic process GO:0006081 4 0.075
myofibril assembly GO:0030239 48 0.074
cellular component morphogenesis GO:0032989 336 0.071
lipid storage GO:0019915 1 0.070
single organism organelle organization GO:1902589 199 0.068
muscle cell development GO:0055001 115 0.068
energy reserve metabolic process GO:0006112 2 0.065
purine ribonucleoside biosynthetic process GO:0046129 2 0.063
single organism biosynthetic process GO:0044711 71 0.058
regulation of multicellular organism growth GO:0040014 4 0.057
cellular macromolecular complex assembly GO:0034622 24 0.056
striated muscle cell differentiation GO:0051146 129 0.056
ribose phosphate biosynthetic process GO:0046390 20 0.056
gtp metabolic process GO:0046039 4 0.053
regulation of binding GO:0051098 3 0.053
neuron projection morphogenesis GO:0048812 161 0.052
small molecule metabolic process GO:0044281 77 0.052
single organism membrane fusion GO:0044801 2 0.051
muscle structure development GO:0061061 196 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.050
organelle organization GO:0006996 227 0.049
cytoskeleton organization GO:0007010 96 0.049
regulation of cell shape GO:0008360 1 0.049
regulation of protein transport GO:0051223 3 0.048
regulation of establishment of protein localization GO:0070201 4 0.048
biosynthetic process GO:0009058 294 0.046
regulation of receptor activity GO:0010469 2 0.046
nucleoside triphosphate biosynthetic process GO:0009142 2 0.045
maintenance of location GO:0051235 4 0.045
cellular protein complex assembly GO:0043623 19 0.044
protein acylation GO:0043543 3 0.044
multicellular organism growth GO:0035264 4 0.044
carbohydrate derivative metabolic process GO:1901135 61 0.043
membrane fusion GO:0061025 2 0.042
internal protein amino acid acetylation GO:0006475 2 0.042
dicarboxylic acid metabolic process GO:0043648 1 0.041
locomotion GO:0040011 313 0.040
transport GO:0006810 220 0.040
guanosine containing compound catabolic process GO:1901069 2 0.040
cellular protein catabolic process GO:0044257 4 0.039
establishment of protein localization to organelle GO:0072594 4 0.039
organic substance biosynthetic process GO:1901576 289 0.039
synaptic growth at neuromuscular junction GO:0051124 2 0.037
proteasomal protein catabolic process GO:0010498 2 0.037
gtp catabolic process GO:0006184 2 0.036
ubiquitin dependent protein catabolic process GO:0006511 3 0.036
macromolecule biosynthetic process GO:0009059 227 0.036
purine nucleoside biosynthetic process GO:0042451 2 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
cellular ketone metabolic process GO:0042180 11 0.035
cellular nitrogen compound biosynthetic process GO:0044271 218 0.035
regulation of cellular ketone metabolic process GO:0010565 7 0.035
cellular response to extracellular stimulus GO:0031668 2 0.035
cellular carbohydrate metabolic process GO:0044262 4 0.035
protein polymerization GO:0051258 4 0.034
monovalent inorganic cation transport GO:0015672 42 0.034
growth GO:0040007 174 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
positive regulation of secretion by cell GO:1903532 1 0.034
protein complex assembly GO:0006461 30 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
cellular macromolecule metabolic process GO:0044260 391 0.032
guanosine containing compound metabolic process GO:1901068 4 0.031
regulation of protein complex assembly GO:0043254 3 0.031
organic acid metabolic process GO:0006082 31 0.031
regionalization GO:0003002 274 0.031
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.031
regulation of ph GO:0006885 3 0.031
oxidation reduction process GO:0055114 41 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.030
neurotransmitter transport GO:0006836 2 0.030
positive regulation of transport GO:0051050 2 0.030
carboxylic acid metabolic process GO:0019752 22 0.030
cellular biosynthetic process GO:0044249 286 0.030
regulation of cytokine production GO:0001817 3 0.029
oocyte anterior posterior axis specification GO:0007314 4 0.029
cellular response to external stimulus GO:0071496 2 0.029
actin cytoskeleton organization GO:0030036 63 0.029
regulation of macromolecule metabolic process GO:0060255 317 0.028
regulation of sodium ion transport GO:0002028 2 0.028
nucleoside monophosphate biosynthetic process GO:0009124 1 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
segmentation GO:0035282 97 0.028
localization of cell GO:0051674 244 0.028
regulation of signal transduction GO:0009966 225 0.028
reactive nitrogen species metabolic process GO:2001057 0 0.027
cellular component assembly GO:0022607 170 0.027
nucleoside biosynthetic process GO:0009163 2 0.027
chordate embryonic development GO:0043009 271 0.027
regulation of biological quality GO:0065008 263 0.027
hepaticobiliary system development GO:0061008 98 0.026
phagocytosis GO:0006909 3 0.025
regulation of protein catabolic process GO:0042176 1 0.025
macromolecular complex assembly GO:0065003 35 0.024
response to nutrient GO:0007584 3 0.024
somitogenesis GO:0001756 87 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
nucleoside monophosphate catabolic process GO:0009125 4 0.024
zymogen activation GO:0031638 3 0.024
protein complex biogenesis GO:0070271 30 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
response to external stimulus GO:0009605 264 0.023
purine nucleotide metabolic process GO:0006163 27 0.023
centrosome cycle GO:0007098 1 0.023
amine metabolic process GO:0009308 2 0.023
alcohol biosynthetic process GO:0046165 2 0.023
system process GO:0003008 185 0.022
microtubule organizing center organization GO:0031023 1 0.022
positive regulation of apoptotic signaling pathway GO:2001235 1 0.022
carbohydrate metabolic process GO:0005975 12 0.022
ribonucleotide biosynthetic process GO:0009260 20 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
regulation of metabolic process GO:0019222 359 0.021
ribonucleoside biosynthetic process GO:0042455 2 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
single fertilization GO:0007338 3 0.021
phosphorus metabolic process GO:0006793 109 0.020
leukocyte proliferation GO:0070661 1 0.020
pole plasm assembly GO:0007315 4 0.020
protein complex subunit organization GO:0071822 46 0.020
transmembrane transport GO:0055085 120 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
positive regulation of cytokine production GO:0001819 2 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
developmental growth GO:0048589 166 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
protein import GO:0017038 3 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
single organism nuclear import GO:1902593 3 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
regulation of oocyte development GO:0060281 3 0.019
regulation of cell death GO:0010941 103 0.019
heterocycle biosynthetic process GO:0018130 215 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
macromolecule modification GO:0043412 111 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
regulation of circadian rhythm GO:0042752 4 0.018
glycosyl compound biosynthetic process GO:1901659 2 0.018
oxoacid metabolic process GO:0043436 31 0.018
centrosome organization GO:0051297 1 0.018
ribonucleotide metabolic process GO:0009259 27 0.018
rna localization GO:0006403 4 0.018
sensory perception of touch GO:0050975 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of dna replication GO:0006275 3 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
regulation of reproductive process GO:2000241 4 0.017
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.017
myotube differentiation GO:0014902 45 0.017
cell part morphogenesis GO:0032990 246 0.017
nuclear import GO:0051170 3 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
protein secretion GO:0009306 1 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
organophosphate biosynthetic process GO:0090407 23 0.017
stem cell maintenance GO:0019827 4 0.017
cell fate commitment GO:0045165 99 0.016
cellular amine metabolic process GO:0044106 2 0.016
cellular component movement GO:0006928 335 0.016
protein dephosphorylation GO:0006470 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
neuron projection development GO:0031175 180 0.016
purine containing compound metabolic process GO:0072521 29 0.016
synaptic vesicle transport GO:0048489 1 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
cellular respiration GO:0045333 3 0.016
nucleic acid templated transcription GO:0097659 181 0.016
cytoplasm organization GO:0007028 4 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
nuclear transport GO:0051169 4 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.015
myoblast fusion GO:0007520 10 0.015
stem cell proliferation GO:0072089 4 0.015
liver development GO:0001889 96 0.015
glutamate receptor signaling pathway GO:0007215 1 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
nephron morphogenesis GO:0072028 2 0.015
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
cellular component disassembly GO:0022411 1 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
regulation of cell communication GO:0010646 232 0.015
cell morphogenesis GO:0000902 289 0.015
response to hypoxia GO:0001666 25 0.015
lipid catabolic process GO:0016042 4 0.015
establishment of localization GO:0051234 244 0.015
response to amphetamine GO:0001975 1 0.015
cortical actin cytoskeleton organization GO:0030866 1 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
tube morphogenesis GO:0035239 349 0.015
transcription dna templated GO:0006351 181 0.015
regulation of intracellular protein transport GO:0033157 3 0.014
cellular protein metabolic process GO:0044267 129 0.014
cell motility GO:0048870 244 0.014
protein homooligomerization GO:0051260 3 0.014
midbrain development GO:0030901 28 0.014
sensory organ development GO:0007423 393 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
response to organic substance GO:0010033 153 0.014
response to oxygen levels GO:0070482 25 0.014
rna transport GO:0050658 2 0.014
protein localization to nucleus GO:0034504 3 0.014
homeostatic process GO:0042592 142 0.014
primary neural tube formation GO:0014020 1 0.014
regulation of cell maturation GO:1903429 1 0.014
regulation of protein targeting GO:1903533 2 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
regulation of cellular ph GO:0030641 1 0.014
negative regulation of catabolic process GO:0009895 3 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.013
epithelial cell differentiation GO:0030855 116 0.013
cell cell signaling GO:0007267 52 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
regulation of metal ion transport GO:0010959 4 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
positive regulation of secretion GO:0051047 1 0.013
blood vessel morphogenesis GO:0048514 216 0.013
regulation of endothelial cell proliferation GO:0001936 1 0.013
cellular protein modification process GO:0006464 100 0.013
negative regulation of protein transport GO:0051224 3 0.013
regulation of response to stimulus GO:0048583 269 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
sleep GO:0030431 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
membrane invagination GO:0010324 1 0.013
electron transport chain GO:0022900 2 0.013
positive regulation of catabolic process GO:0009896 4 0.013
anterior posterior pattern specification GO:0009952 152 0.013
meiotic cell cycle process GO:1903046 3 0.013
central nervous system development GO:0007417 387 0.013
protein complex disassembly GO:0043241 1 0.012
regulation of sodium ion transmembrane transport GO:1902305 1 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
entrainment of circadian clock GO:0009649 2 0.012
monocarboxylic acid biosynthetic process GO:0072330 12 0.012
digestive system development GO:0055123 289 0.012
regulation of developmental process GO:0050793 247 0.012
cardiac atrium development GO:0003230 4 0.012
nucleotide metabolic process GO:0009117 28 0.012
intracellular mrna localization GO:0008298 1 0.012
vacuole organization GO:0007033 9 0.012
entrainment of circadian clock by photoperiod GO:0043153 1 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
purine nucleotide biosynthetic process GO:0006164 20 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
neuron development GO:0048666 262 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
protein localization to plasma membrane GO:0072659 1 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
purine ribonucleotide biosynthetic process GO:0009152 20 0.012
nuclear export GO:0051168 1 0.012
angiogenesis GO:0001525 158 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
response to mechanical stimulus GO:0009612 24 0.012
positive regulation of biological process GO:0048518 253 0.012
response to copper ion GO:0046688 13 0.012
organophosphate metabolic process GO:0019637 37 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.011
macromolecule localization GO:0033036 54 0.011
membrane hyperpolarization GO:0060081 1 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
neurotransmitter secretion GO:0007269 2 0.011
germ line stem cell maintenance GO:0030718 2 0.011
organ regeneration GO:0031100 1 0.011
somite development GO:0061053 96 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
tissue regeneration GO:0042246 74 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
regeneration GO:0031099 91 0.011
protein acetylation GO:0006473 2 0.011
single organism membrane organization GO:0044802 20 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
protein modification by small protein removal GO:0070646 1 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
renal tubule morphogenesis GO:0061333 1 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
response to virus GO:0009615 21 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
syncytium formation GO:0006949 12 0.011
regulation of cell activation GO:0050865 1 0.011
fatty acid oxidation GO:0019395 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
heterocycle metabolic process GO:0046483 290 0.011
neuron differentiation GO:0030182 353 0.011
response to abiotic stimulus GO:0009628 122 0.011
actin filament polymerization GO:0030041 2 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
protein depolymerization GO:0051261 1 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
tissue remodeling GO:0048771 4 0.011
cellular component biogenesis GO:0044085 178 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of organelle organization GO:0033043 29 0.011
small molecule catabolic process GO:0044282 3 0.011
regulation of dna templated transcription in response to stress GO:0043620 0 0.011
nuclear migration GO:0007097 3 0.011
signal transduction GO:0007165 455 0.011
establishment of rna localization GO:0051236 3 0.011
response to chemical GO:0042221 320 0.011
cell cell signaling involved in cell fate commitment GO:0045168 12 0.011
response to corticosteroid GO:0031960 1 0.011
atp catabolic process GO:0006200 4 0.011
regulation of intracellular ph GO:0051453 1 0.011
protein targeting to nucleus GO:0044744 3 0.011
head development GO:0060322 303 0.010
regulation of signaling GO:0023051 235 0.010
synaptic vesicle endocytosis GO:0048488 1 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
cell projection morphogenesis GO:0048858 244 0.010
synaptic vesicle localization GO:0097479 1 0.010
protein import into nucleus GO:0006606 3 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
regulation of cell differentiation GO:0045595 142 0.010
multi organism process GO:0051704 134 0.010
regulation of peptidase activity GO:0052547 23 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
gene expression GO:0010467 252 0.010
adult behavior GO:0030534 2 0.010
glycosyl compound metabolic process GO:1901657 11 0.010
peptide metabolic process GO:0006518 1 0.010
regulation of protein binding GO:0043393 3 0.010
regulation of blood pressure GO:0008217 1 0.010

pgk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.021
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.014
acquired metabolic disease DOID:0060158 0 0.014
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
musculoskeletal system disease DOID:17 0 0.012
cardiovascular system disease DOID:1287 0 0.011