Danio rerio

55 known processes

ppp4ca

protein phosphatase 4 (formerly X), catalytic subunit a

(Aliases: zgc:56413,gc:56413,ppp4c,wu:fd05e08,PP4C-A,pp4c)

ppp4ca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.694
gene expression GO:0010467 252 0.591
cellular macromolecule metabolic process GO:0044260 391 0.584
Human Yeast
cellular macromolecule biosynthetic process GO:0034645 224 0.534
cellular aromatic compound metabolic process GO:0006725 295 0.513
Human Yeast
heterocycle metabolic process GO:0046483 290 0.511
Human Yeast
regulation of macromolecule metabolic process GO:0060255 317 0.455
Human Yeast
regulation of rna biosynthetic process GO:2001141 213 0.452
cellular biosynthetic process GO:0044249 286 0.416
regulation of macromolecule biosynthetic process GO:0010556 225 0.409
regulation of gene expression GO:0010468 265 0.394
regulation of cellular metabolic process GO:0031323 320 0.379
Human Yeast
regulation of cellular biosynthetic process GO:0031326 245 0.358
nucleobase containing compound biosynthetic process GO:0034654 205 0.356
macromolecule biosynthetic process GO:0009059 227 0.347
negative regulation of biological process GO:0048519 304 0.339
Yeast
aromatic compound biosynthetic process GO:0019438 217 0.314
regulation of nitrogen compound metabolic process GO:0051171 251 0.306
Human Yeast
larval development GO:0002164 2 0.301
regulation of biosynthetic process GO:0009889 250 0.280
nitrogen compound metabolic process GO:0006807 319 0.276
Human Yeast
organic substance biosynthetic process GO:1901576 289 0.276
nucleobase containing compound metabolic process GO:0006139 274 0.254
Human Yeast
nucleic acid metabolic process GO:0090304 244 0.245
Human Yeast
single organism metabolic process GO:0044710 217 0.245
Human Yeast
biosynthetic process GO:0009058 294 0.244
heterocycle biosynthetic process GO:0018130 215 0.241
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.239
Human Yeast
positive regulation of cell cycle GO:0045787 3 0.222
rna biosynthetic process GO:0032774 181 0.204
embryo development ending in birth or egg hatching GO:0009792 271 0.193
regulation of meiotic cell cycle GO:0051445 1 0.192
Yeast
organic cyclic compound metabolic process GO:1901360 301 0.180
Human Yeast
organic cyclic compound biosynthetic process GO:1901362 223 0.178
regulation of metabolic process GO:0019222 359 0.177
Human Yeast
regulation of primary metabolic process GO:0080090 311 0.173
Human Yeast
regulation of nucleic acid templated transcription GO:1903506 213 0.171
cellular response to dna damage stimulus GO:0006974 24 0.159
Human Yeast
positive regulation of cellular process GO:0048522 201 0.158
Yeast
regulation of rna metabolic process GO:0051252 224 0.156
homeostatic process GO:0042592 142 0.145
Yeast
nucleic acid templated transcription GO:0097659 181 0.139
transcription dna templated GO:0006351 181 0.132
rna metabolic process GO:0016070 219 0.122
cellular nitrogen compound biosynthetic process GO:0044271 218 0.117
aging GO:0007568 2 0.109
establishment of protein localization to organelle GO:0072594 4 0.106
regulation of cell communication GO:0010646 232 0.106
Yeast
regulation of transcription dna templated GO:0006355 213 0.105
regulation of response to stimulus GO:0048583 269 0.103
Human Yeast
i kappab kinase nf kappab signaling GO:0007249 4 0.102
morphogenesis of an epithelium GO:0002009 333 0.101
mitotic dna integrity checkpoint GO:0044774 4 0.095
digestive system development GO:0055123 289 0.089
mrna metabolic process GO:0016071 20 0.086
establishment of localization GO:0051234 244 0.085
phagocytosis GO:0006909 3 0.082
digestive tract development GO:0048565 265 0.081
immune system process GO:0002376 241 0.080
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.077
organelle organization GO:0006996 227 0.076
regionalization GO:0003002 274 0.070
cellular nitrogen compound metabolic process GO:0034641 290 0.070
Human Yeast
proteasomal protein catabolic process GO:0010498 2 0.069
regulation of protein catabolic process GO:0042176 1 0.067
transport GO:0006810 220 0.066
regulation of signal transduction GO:0009966 225 0.065
Yeast
programmed cell death GO:0012501 119 0.065
nuclear import GO:0051170 3 0.063
mitotic dna damage checkpoint GO:0044773 4 0.061
negative regulation of gene expression GO:0010629 65 0.061
rna processing GO:0006396 25 0.060
single organism transport GO:0044765 206 0.059
mitotic g2 m transition checkpoint GO:0044818 3 0.059
chromatin modification GO:0016568 21 0.059
nuclear transport GO:0051169 4 0.059
transcription from rna polymerase ii promoter GO:0006366 80 0.058
regulation of signaling GO:0023051 235 0.057
Yeast
positive regulation of biological process GO:0048518 253 0.057
Yeast
single organism organelle organization GO:1902589 199 0.053
g1 s transition of mitotic cell cycle GO:0000082 1 0.052
cell cycle GO:0007049 93 0.051
Yeast Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.050
cell cycle g1 s phase transition GO:0044843 1 0.050
tube morphogenesis GO:0035239 349 0.048
signal transduction GO:0007165 455 0.047
Yeast
response to stress GO:0006950 263 0.047
Human Yeast
protein localization to nucleus GO:0034504 3 0.046
negative regulation of signal transduction GO:0009968 94 0.045
Yeast
positive regulation of signal transduction GO:0009967 56 0.044
regulation of translational initiation GO:0006446 1 0.044
signal transduction by p53 class mediator GO:0072331 13 0.043
regulation of dna replication GO:0006275 3 0.043
regulation of mitotic cell cycle phase transition GO:1901990 8 0.042
phagocytosis engulfment GO:0006911 1 0.042
interspecies interaction between organisms GO:0044419 4 0.042
negative regulation of biosynthetic process GO:0009890 55 0.041
cellular protein metabolic process GO:0044267 129 0.040
Yeast
heart development GO:0007507 313 0.040
positive regulation of catabolic process GO:0009896 4 0.039
regulation of neutrophil migration GO:1902622 6 0.039
regulation of establishment of protein localization GO:0070201 4 0.038
intracellular signal transduction GO:0035556 85 0.037
Yeast
regulation of biological quality GO:0065008 263 0.037
Yeast
autophagy GO:0006914 4 0.036
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.036
reproduction GO:0000003 40 0.036
Yeast
digestive tract morphogenesis GO:0048546 231 0.035
small molecule metabolic process GO:0044281 77 0.035
regulation of cellular protein metabolic process GO:0032268 52 0.035
protein acetylation GO:0006473 2 0.034
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.034
positive regulation of cellular metabolic process GO:0031325 94 0.033
Yeast
peptidyl lysine acetylation GO:0018394 2 0.033
negative regulation of metabolic process GO:0009892 86 0.033
protein metabolic process GO:0019538 183 0.033
Yeast
ion transport GO:0006811 114 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.032
ameboidal type cell migration GO:0001667 143 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
regulation of response to stress GO:0080134 36 0.031
Human Yeast
single organism localization GO:1902578 225 0.031
regulation of protein transport GO:0051223 3 0.030
rna 3 end processing GO:0031123 2 0.030
vasculature development GO:0001944 278 0.030
regulation of mitotic cell cycle GO:0007346 25 0.030
Fly
positive regulation of transport GO:0051050 2 0.029
microtubule organizing center organization GO:0031023 1 0.029
protein sumoylation GO:0016925 2 0.029
internal protein amino acid acetylation GO:0006475 2 0.028
mrna processing GO:0006397 14 0.028
generation of neurons GO:0048699 385 0.028
central nervous system development GO:0007417 387 0.027
negative regulation of rna metabolic process GO:0051253 48 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
protein complex localization GO:0031503 1 0.027
macromolecule modification GO:0043412 111 0.027
Yeast
mitotic g2 dna damage checkpoint GO:0007095 3 0.027
regulation of signal transduction by p53 class mediator GO:1901796 9 0.027
multi organism cellular process GO:0044764 2 0.027
internal peptidyl lysine acetylation GO:0018393 2 0.026
protein import into nucleus GO:0006606 3 0.026
regulation of protein metabolic process GO:0051246 56 0.026
negative regulation of protein transport GO:0051224 3 0.026
negative regulation of mitosis GO:0045839 3 0.026
regulation of cell cycle GO:0051726 52 0.026
Yeast Fly
positive regulation of gene expression GO:0010628 71 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
locomotion GO:0040011 313 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
protein acylation GO:0043543 3 0.025
single organism nuclear import GO:1902593 3 0.025
regulation of phosphorus metabolic process GO:0051174 43 0.025
mrna transport GO:0051028 2 0.025
anterior posterior pattern specification GO:0009952 152 0.024
dorsal ventral pattern formation GO:0009953 125 0.024
histone modification GO:0016570 20 0.024
viral process GO:0016032 1 0.024
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.024
regulation of nucleocytoplasmic transport GO:0046822 2 0.024
cellular protein modification process GO:0006464 100 0.024
Yeast
response to glucose GO:0009749 3 0.024
Yeast
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
nuclear export GO:0051168 1 0.023
positive regulation of cellular biosynthetic process GO:0031328 68 0.023
sensory organ development GO:0007423 393 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
regulation of molecular function GO:0065009 70 0.023
regulation of binding GO:0051098 3 0.022
posttranscriptional regulation of gene expression GO:0010608 14 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
organic acid metabolic process GO:0006082 31 0.022
mrna catabolic process GO:0006402 6 0.022
ncrna metabolic process GO:0034660 12 0.022
liver development GO:0001889 96 0.022
oxoacid metabolic process GO:0043436 31 0.022
protein polyubiquitination GO:0000209 4 0.022
cell cycle process GO:0022402 53 0.022
Yeast
apoptotic process GO:0006915 116 0.022
cellular response to external stimulus GO:0071496 2 0.021
g2 dna damage checkpoint GO:0031572 3 0.021
response to wounding GO:0009611 116 0.021
protein targeting to nucleus GO:0044744 3 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
stem cell differentiation GO:0048863 117 0.021
rna localization GO:0006403 4 0.021
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.021
cell migration GO:0016477 237 0.020
blood vessel development GO:0001568 246 0.020
chemical homeostasis GO:0048878 49 0.020
Yeast
cellular amine metabolic process GO:0044106 2 0.020
chromosome organization GO:0051276 31 0.020
cellular localization GO:0051641 97 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
convergent extension GO:0060026 118 0.020
cellular response to starvation GO:0009267 1 0.020
cellular response to stress GO:0033554 62 0.020
Human Yeast
positive regulation of response to stimulus GO:0048584 80 0.019
Yeast
response to monosaccharide GO:0034284 3 0.019
Yeast
growth GO:0040007 174 0.019
protein import GO:0017038 3 0.019
nucleic acid transport GO:0050657 2 0.019
gastrulation GO:0007369 208 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
phosphorus metabolic process GO:0006793 109 0.019
Human Yeast Rat
positive regulation of cell communication GO:0010647 56 0.019
regulation of programmed cell death GO:0043067 101 0.018
negative regulation of catabolic process GO:0009895 3 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
heart morphogenesis GO:0003007 156 0.018
protein dephosphorylation GO:0006470 3 0.018
Yeast
negative regulation of multicellular organismal process GO:0051241 69 0.018
photoreceptor cell development GO:0042461 40 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
rna transport GO:0050658 2 0.018
mitotic cell cycle GO:0000278 64 0.018
Fly
multi organism process GO:0051704 134 0.018
cellular component assembly GO:0022607 170 0.018
centrosome organization GO:0051297 1 0.018
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.018
protein localization GO:0008104 40 0.017
regulation of apoptotic process GO:0042981 98 0.017
neutrophil mediated immunity GO:0002446 1 0.017
response to organic substance GO:0010033 153 0.017
Yeast Rat
positive regulation of rna metabolic process GO:0051254 59 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
negative regulation of cellular process GO:0048523 283 0.017
Yeast
regulation of cell shape GO:0008360 1 0.016
nucleobase containing compound transport GO:0015931 2 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
macromolecule localization GO:0033036 54 0.016
embryonic organ development GO:0048568 381 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.016
protein polymerization GO:0051258 4 0.016
single organism cellular localization GO:1902580 46 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
Human Yeast Rat
regulation of localization GO:0032879 104 0.016
regulation of cellular component movement GO:0051270 55 0.015
brain development GO:0007420 293 0.015
cell proliferation GO:0008283 80 0.015
protein localization to plasma membrane GO:0072659 1 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
Yeast
hematopoietic or lymphoid organ development GO:0048534 191 0.015
convergent extension involved in gastrulation GO:0060027 71 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
synaptic vesicle localization GO:0097479 1 0.015
cellular response to nutrient levels GO:0031669 2 0.015
cellular macromolecular complex assembly GO:0034622 24 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
Yeast
cellular response to organic substance GO:0071310 105 0.015
Yeast Rat
cellular component biogenesis GO:0044085 178 0.015
dna integrity checkpoint GO:0031570 6 0.015
Yeast
negative regulation of signaling GO:0023057 96 0.015
Yeast
negative regulation of intracellular transport GO:0032387 3 0.014
cellular protein catabolic process GO:0044257 4 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
macromolecular complex assembly GO:0065003 35 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
urogenital system development GO:0001655 97 0.014
cell motility GO:0048870 244 0.014
cell cycle g2 m phase transition GO:0044839 4 0.014
organic substance transport GO:0071702 58 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
cell projection organization GO:0030030 284 0.014
regulation of locomotion GO:0040012 55 0.014
hemopoiesis GO:0030097 183 0.013
cellular catabolic process GO:0044248 27 0.013
cellular nitrogen compound catabolic process GO:0044270 15 0.013
rna export from nucleus GO:0006405 1 0.013
modification dependent protein catabolic process GO:0019941 3 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
fertilization GO:0009566 3 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
myeloid leukocyte migration GO:0097529 12 0.013
mrna 3 end processing GO:0031124 2 0.013
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.013
spliceosomal complex assembly GO:0000245 1 0.013
regulation of autophagy GO:0010506 3 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
negative regulation of response to dna damage stimulus GO:2001021 3 0.013
Yeast
regulation of phosphate metabolic process GO:0019220 43 0.013
system process GO:0003008 185 0.013
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
establishment or maintenance of cell polarity GO:0007163 29 0.013
regulation of cell death GO:0010941 103 0.013
segmentation GO:0035282 97 0.013
nitrogen compound transport GO:0071705 23 0.012
membrane organization GO:0061024 21 0.012
regulation of gene expression epigenetic GO:0040029 11 0.012
regulation of protein targeting GO:1903533 2 0.012
mitochondrion organization GO:0007005 4 0.012
meiotic nuclear division GO:0007126 4 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
protein secretion GO:0009306 1 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.012
nucleobase containing compound catabolic process GO:0034655 15 0.012
negative regulation of cell communication GO:0010648 96 0.012
Yeast
developmental growth involved in morphogenesis GO:0060560 86 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of cell cycle phase transition GO:1901987 8 0.012
Yeast
developmental growth GO:0048589 166 0.012
regulation of organelle organization GO:0033043 29 0.012
Yeast
heart process GO:0003015 71 0.011
neuron differentiation GO:0030182 353 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
aromatic compound catabolic process GO:0019439 15 0.011
membrane invagination GO:0010324 1 0.011
protein complex disassembly GO:0043241 1 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
meiosis ii GO:0007135 1 0.011
positive regulation of metabolic process GO:0009893 108 0.011
Yeast
protein deacetylation GO:0006476 3 0.011
3 utr mediated mrna stabilization GO:0070935 3 0.011
negative regulation of mitotic cell cycle GO:0045930 11 0.011
leukocyte homeostasis GO:0001776 2 0.011
synaptic vesicle transport GO:0048489 1 0.011
regulation of cell motility GO:2000145 46 0.011
mitotic cell cycle process GO:1903047 48 0.011
organism emergence from protective structure GO:0071684 4 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
cell growth GO:0016049 57 0.011
translational initiation GO:0006413 3 0.010
embryonic limb morphogenesis GO:0030326 2 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
eye morphogenesis GO:0048592 144 0.010
cell death GO:0008219 121 0.010
regulation of cytokine production GO:0001817 3 0.010
histone deacetylation GO:0016575 2 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
cell cycle checkpoint GO:0000075 7 0.010
Yeast
negative regulation of signal transduction by p53 class mediator GO:1901797 8 0.010
meiosis i GO:0007127 1 0.010
regulation of reproductive process GO:2000241 4 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
meiotic cell cycle process GO:1903046 3 0.010
Yeast
carbohydrate homeostasis GO:0033500 1 0.010
Yeast

ppp4ca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010