Danio rerio

0 known processes

pdgfrl

platelet-derived growth factor receptor-like

(Aliases: zgc:56104,MGC56104,zgc:77677)

pdgfrl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.205
blood vessel morphogenesis GO:0048514 216 0.203
response to chemical GO:0042221 320 0.178
lymphoid lineage cell migration into thymus GO:0097535 4 0.172
cellular nitrogen compound metabolic process GO:0034641 290 0.167
embryonic organ morphogenesis GO:0048562 274 0.160
extracellular structure organization GO:0043062 27 0.154
extracellular matrix organization GO:0030198 27 0.148
mesenchymal cell differentiation GO:0048762 87 0.143
embryonic organ development GO:0048568 381 0.139
vasculature development GO:0001944 278 0.133
basement membrane assembly GO:0070831 3 0.118
camera type eye development GO:0043010 222 0.108
organonitrogen compound metabolic process GO:1901564 74 0.107
stem cell differentiation GO:0048863 117 0.105
regulation of rna metabolic process GO:0051252 224 0.105
skeletal system development GO:0001501 181 0.103
response to vitamin GO:0033273 3 0.094
chordate embryonic development GO:0043009 271 0.093
nitrogen compound metabolic process GO:0006807 319 0.088
negative regulation of developmental process GO:0051093 65 0.087
regulation of cell communication GO:0010646 232 0.086
collagen fibril organization GO:0030199 1 0.084
oxoacid metabolic process GO:0043436 31 0.083
head development GO:0060322 303 0.079
response to amino acid GO:0043200 2 0.079
axon ensheathment GO:0008366 18 0.077
axon ensheathment in central nervous system GO:0032291 2 0.077
cellular component morphogenesis GO:0032989 336 0.076
nucleic acid templated transcription GO:0097659 181 0.075
developmental growth involved in morphogenesis GO:0060560 86 0.072
ameboidal type cell migration GO:0001667 143 0.070
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.070
cellular response to retinoic acid GO:0071300 1 0.068
heterocycle biosynthetic process GO:0018130 215 0.064
regulation of anatomical structure morphogenesis GO:0022603 130 0.064
regulation of signaling GO:0023051 235 0.064
tissue remodeling GO:0048771 4 0.063
spermatid development GO:0007286 2 0.063
skeletal system morphogenesis GO:0048705 102 0.063
cellular biosynthetic process GO:0044249 286 0.062
stem cell development GO:0048864 82 0.062
mesenchyme development GO:0060485 127 0.061
epithelial to mesenchymal transition GO:0001837 21 0.060
regulation of cellular biosynthetic process GO:0031326 245 0.060
positive regulation of cellular metabolic process GO:0031325 94 0.057
angiogenesis GO:0001525 158 0.057
positive regulation of cellular biosynthetic process GO:0031328 68 0.056
embryo development ending in birth or egg hatching GO:0009792 271 0.055
blood vessel development GO:0001568 246 0.055
organic substance biosynthetic process GO:1901576 289 0.052
transcription dna templated GO:0006351 181 0.051
embryonic skeletal joint morphogenesis GO:0060272 3 0.051
cellular nitrogen compound biosynthetic process GO:0044271 218 0.050
aromatic compound biosynthetic process GO:0019438 217 0.050
action potential GO:0001508 19 0.050
morphogenesis of an epithelium GO:0002009 333 0.050
negative regulation of biological process GO:0048519 304 0.050
regulation of vasculature development GO:1901342 33 0.049
positive regulation of rna metabolic process GO:0051254 59 0.049
trabecula formation GO:0060343 2 0.048
sensory organ development GO:0007423 393 0.048
regulation of developmental process GO:0050793 247 0.047
cerebellar granular layer development GO:0021681 3 0.047
positive regulation of cellular amine metabolic process GO:0033240 0 0.046
bone development GO:0060348 14 0.045
regulation of macromolecule metabolic process GO:0060255 317 0.044
regulation of cellular metabolic process GO:0031323 320 0.044
growth plate cartilage development GO:0003417 2 0.043
mesenchymal cell development GO:0014031 78 0.043
carboxylic acid metabolic process GO:0019752 22 0.042
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
muscle structure development GO:0061061 196 0.042
biosynthetic process GO:0009058 294 0.042
positive regulation of cellular process GO:0048522 201 0.041
muscle cell differentiation GO:0042692 139 0.039
organic acid metabolic process GO:0006082 31 0.039
neurological system process GO:0050877 62 0.038
macromolecule biosynthetic process GO:0009059 227 0.038
larval development GO:0002164 2 0.037
gene expression GO:0010467 252 0.037
regulation of response to stimulus GO:0048583 269 0.037
embryonic skeletal system development GO:0048706 97 0.037
small molecule metabolic process GO:0044281 77 0.037
regulation of multicellular organismal development GO:2000026 223 0.036
regulation of biological quality GO:0065008 263 0.036
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
regulation of macromolecule biosynthetic process GO:0010556 225 0.036
nucleocytoplasmic transport GO:0006913 4 0.035
regulation of nucleic acid templated transcription GO:1903506 213 0.035
axon development GO:0061564 166 0.035
cellular macromolecule biosynthetic process GO:0034645 224 0.035
single organism metabolic process GO:0044710 217 0.035
cartilage condensation GO:0001502 3 0.034
regulation of protein ubiquitination GO:0031396 3 0.034
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.033
protein metabolic process GO:0019538 183 0.033
connective tissue development GO:0061448 99 0.032
response to nutrient GO:0007584 3 0.032
neuron differentiation GO:0030182 353 0.032
cell motility GO:0048870 244 0.031
negative regulation of signaling GO:0023057 96 0.031
regulation of cytokine production GO:0001817 3 0.031
carbohydrate derivative metabolic process GO:1901135 61 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.030
regulation of intracellular signal transduction GO:1902531 57 0.030
regulation of epithelial cell proliferation GO:0050678 3 0.029
spermatid differentiation GO:0048515 2 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
cellular response to external stimulus GO:0071496 2 0.029
sensory organ morphogenesis GO:0090596 200 0.028
regulation of multicellular organismal process GO:0051239 277 0.028
transmission of nerve impulse GO:0019226 19 0.028
cellular component biogenesis GO:0044085 178 0.028
endochondral bone growth GO:0003416 2 0.027
cellular response to nutrient levels GO:0031669 2 0.027
basement membrane organization GO:0071711 5 0.027
digestive system development GO:0055123 289 0.027
positive regulation of cell development GO:0010720 25 0.026
myelination GO:0042552 18 0.026
regulation of cell shape GO:0008360 1 0.026
transport GO:0006810 220 0.026
single organism transport GO:0044765 206 0.026
regulation of cell development GO:0060284 100 0.025
regulation of reactive oxygen species metabolic process GO:2000377 2 0.025
nucleic acid metabolic process GO:0090304 244 0.025
urogenital system development GO:0001655 97 0.025
negative regulation of cellular process GO:0048523 283 0.025
neuron development GO:0048666 262 0.025
development of primary female sexual characteristics GO:0046545 4 0.025
appendage development GO:0048736 80 0.024
aging GO:0007568 2 0.024
branching morphogenesis of a nerve GO:0048755 4 0.023
embryonic skeletal joint development GO:0072498 3 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
cell proliferation GO:0008283 80 0.023
rna metabolic process GO:0016070 219 0.023
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.023
regulation of gene expression GO:0010468 265 0.023
myelin assembly GO:0032288 1 0.023
locomotion GO:0040011 313 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of chondrocyte differentiation GO:0032330 1 0.022
negative regulation of dna metabolic process GO:0051053 4 0.022
response to wounding GO:0009611 116 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
fin development GO:0033333 77 0.022
embryonic eye morphogenesis GO:0048048 30 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
positive regulation of cytokine production GO:0001819 2 0.021
response to inorganic substance GO:0010035 38 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
multicellular organism growth GO:0035264 4 0.021
rna biosynthetic process GO:0032774 181 0.021
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
neuronal action potential GO:0019228 18 0.020
regulation of transcription dna templated GO:0006355 213 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.019
cartilage development GO:0051216 96 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
growth GO:0040007 174 0.019
stem cell proliferation GO:0072089 4 0.019
regulation of cell substrate adhesion GO:0010810 1 0.018
positive regulation of catabolic process GO:0009896 4 0.018
leukocyte proliferation GO:0070661 1 0.018
regulation of blood pressure GO:0008217 1 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
positive regulation of biological process GO:0048518 253 0.018
biomineral tissue development GO:0031214 13 0.018
regulation of biosynthetic process GO:0009889 250 0.018
regulation of reproductive process GO:2000241 4 0.018
regulation of rna biosynthetic process GO:2001141 213 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.017
regulation of cell growth GO:0001558 29 0.017
cartilage morphogenesis GO:0060536 13 0.017
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.017
meiotic nuclear division GO:0007126 4 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
regulation of primary metabolic process GO:0080090 311 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
fatty acid biosynthetic process GO:0006633 4 0.017
trabecula morphogenesis GO:0061383 2 0.017
developmental growth GO:0048589 166 0.016
multicellular organismal macromolecule metabolic process GO:0044259 2 0.016
localization of cell GO:0051674 244 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
amine metabolic process GO:0009308 2 0.016
collagen metabolic process GO:0032963 2 0.016
regulation of endothelial cell proliferation GO:0001936 1 0.016
tissue regeneration GO:0042246 74 0.016
muscle organ development GO:0007517 101 0.016
appendage morphogenesis GO:0035107 56 0.016
brain development GO:0007420 293 0.016
regulation of metabolic process GO:0019222 359 0.016
response to stress GO:0006950 263 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
camera type eye morphogenesis GO:0048593 108 0.015
cell death GO:0008219 121 0.015
lateral mesoderm development GO:0048368 23 0.015
multicellular organismal signaling GO:0035637 22 0.015
regeneration GO:0031099 91 0.015
regulation of angiogenesis GO:0045765 26 0.015
positive regulation of rna biosynthetic process GO:1902680 57 0.015
mesoderm development GO:0007498 88 0.015
striated muscle tissue development GO:0014706 110 0.015
embryonic camera type eye development GO:0031076 29 0.014
phagocytosis GO:0006909 3 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
system process GO:0003008 185 0.014
cellular component movement GO:0006928 335 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
intracellular signal transduction GO:0035556 85 0.014
regulation of metal ion transport GO:0010959 4 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
ribose phosphate metabolic process GO:0019693 27 0.014
purine ribonucleotide metabolic process GO:0009150 27 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
nuclear transport GO:0051169 4 0.014
central nervous system myelination GO:0022010 2 0.014
cellular response to nutrient GO:0031670 1 0.014
purine nucleotide metabolic process GO:0006163 27 0.014
chondrocyte development GO:0002063 4 0.014
positive regulation of endothelial cell migration GO:0010595 2 0.013
protein import GO:0017038 3 0.013
lymphoid lineage cell migration GO:0097534 4 0.013
cell morphogenesis GO:0000902 289 0.013
atp catabolic process GO:0006200 4 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
aminoglycan metabolic process GO:0006022 9 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of cell activation GO:0050865 1 0.013
cell migration GO:0016477 237 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of cell death GO:0010941 103 0.013
multicellular organismal response to stress GO:0033555 2 0.013
sensory perception GO:0007600 39 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
protein trimerization GO:0070206 4 0.013
eye morphogenesis GO:0048592 144 0.012
regulation of protein targeting GO:1903533 2 0.012
regulation of cell morphogenesis GO:0022604 42 0.012
positive regulation of gene expression GO:0010628 71 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.012
protein heterooligomerization GO:0051291 1 0.012
larval heart development GO:0007508 2 0.012
regulation of localization GO:0032879 104 0.012
neural crest cell differentiation GO:0014033 72 0.012
response to axon injury GO:0048678 14 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
water homeostasis GO:0030104 4 0.012
response to drug GO:0042493 3 0.011
response to topologically incorrect protein GO:0035966 2 0.011
response to organic substance GO:0010033 153 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
lateral line ganglion development GO:0048890 2 0.011
regulation of axonogenesis GO:0050770 32 0.011
astrocyte differentiation GO:0048708 1 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
protein targeting to nucleus GO:0044744 3 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of biomineral tissue development GO:0070167 2 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
cell projection morphogenesis GO:0048858 244 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
positive regulation of cell differentiation GO:0045597 30 0.010
regulation of membrane potential GO:0042391 23 0.010
female gonad development GO:0008585 4 0.010
regulation of establishment of protein localization GO:0070201 4 0.010
regulation of blood vessel size GO:0050880 2 0.010
skeletal muscle organ development GO:0060538 78 0.010
establishment of localization GO:0051234 244 0.010
protein acylation GO:0043543 3 0.010

pdgfrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.106
charcot marie tooth disease type 4 DOID:0050541 0 0.105
neuromuscular disease DOID:440 0 0.105
charcot marie tooth disease DOID:10595 0 0.105
nervous system disease DOID:863 0 0.105
neuropathy DOID:870 0 0.105
bone disease DOID:0080001 0 0.036
musculoskeletal system disease DOID:17 0 0.036
connective tissue disease DOID:65 0 0.036
osteochondrodysplasia DOID:2256 0 0.026
bone development disease DOID:0080006 0 0.026
osteogenesis imperfecta DOID:12347 0 0.023
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.014
bone remodeling disease DOID:0080005 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011