Danio rerio

0 known processes

adrb3b

adrenergic receptor, beta 3b

(Aliases: zgc:194852,MGC194843,MGC194852,zgc:194843)

adrb3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance biosynthetic process GO:1901576 289 0.151
Human Zebrafish
cognition GO:0050890 1 0.144
regulation of cellular biosynthetic process GO:0031326 245 0.113
Human Zebrafish
g protein coupled receptor signaling pathway GO:0007186 74 0.112
Human Zebrafish Mouse Rat
organic cyclic compound biosynthetic process GO:1901362 223 0.104
Human Zebrafish
regulation of primary metabolic process GO:0080090 311 0.094
Human Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.090
Human Zebrafish
cellular biosynthetic process GO:0044249 286 0.087
Human Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.071
regulation of reactive oxygen species metabolic process GO:2000377 2 0.070
regulation of hormone secretion GO:0046883 2 0.069
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.068
phagocytosis GO:0006909 3 0.064
signal transduction GO:0007165 455 0.064
Human Zebrafish Mouse Rat
regulation of biological quality GO:0065008 263 0.062
Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.061
regulation of metabolic process GO:0019222 359 0.061
Human Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.060
larval development GO:0002164 2 0.060
regulation of tube size GO:0035150 2 0.058
Mouse
aging GO:0007568 2 0.058
Rat
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.057
maintenance of location GO:0051235 4 0.056
regulation of synaptic plasticity GO:0048167 1 0.056
single organism metabolic process GO:0044710 217 0.056
Human Zebrafish Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.055
nucleobase containing compound biosynthetic process GO:0034654 205 0.054
Human Zebrafish
biosynthetic process GO:0009058 294 0.051
Human Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.051
Human Zebrafish Mouse Rat
response to external stimulus GO:0009605 264 0.050
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.048
Human Zebrafish
response to bacterium GO:0009617 58 0.047
ubiquitin dependent protein catabolic process GO:0006511 3 0.046
system process GO:0003008 185 0.046
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.046
tissue remodeling GO:0048771 4 0.046
regulation of multicellular organismal process GO:0051239 277 0.045
Zebrafish Mouse
regulation of gene expression GO:0010468 265 0.045
response to stress GO:0006950 263 0.045
Mouse Rat
response to light stimulus GO:0009416 46 0.045
heterocycle biosynthetic process GO:0018130 215 0.044
Human Zebrafish
eye development GO:0001654 277 0.043
hormone secretion GO:0046879 2 0.043
transport GO:0006810 220 0.042
response to chemical GO:0042221 320 0.042
Rat
cellular protein catabolic process GO:0044257 4 0.041
response to wounding GO:0009611 116 0.041
single organism transport GO:0044765 206 0.040
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
regulation of biosynthetic process GO:0009889 250 0.039
Human Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.039
Human Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.039
positive regulation of biological process GO:0048518 253 0.039
Human Mouse
hormone transport GO:0009914 2 0.038
response to carbohydrate GO:0009743 3 0.038
synaptic growth at neuromuscular junction GO:0051124 2 0.038
stem cell proliferation GO:0072089 4 0.038
neurotransmitter transport GO:0006836 2 0.037
positive regulation of transport GO:0051050 2 0.037
regulation of metal ion transport GO:0010959 4 0.036
adult behavior GO:0030534 2 0.035
response to glucose GO:0009749 3 0.035
regulation of signal transduction GO:0009966 225 0.035
Human
transcription dna templated GO:0006351 181 0.035
positive regulation of metabolic process GO:0009893 108 0.034
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.034
positive regulation of cell activation GO:0050867 1 0.034
sequestering of calcium ion GO:0051208 3 0.034
small molecule metabolic process GO:0044281 77 0.033
Human Zebrafish
response to abiotic stimulus GO:0009628 122 0.033
Mouse Rat
regulation of signaling GO:0023051 235 0.033
Human
response to radiation GO:0009314 51 0.033
regulation of cell activation GO:0050865 1 0.032
regulation of protein complex assembly GO:0043254 3 0.032
amine metabolic process GO:0009308 2 0.031
release of sequestered calcium ion into cytosol GO:0051209 3 0.030
sensory perception of chemical stimulus GO:0007606 3 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
regulation of rna biosynthetic process GO:2001141 213 0.029
endocrine process GO:0050886 2 0.029
negative regulation of sequestering of calcium ion GO:0051283 4 0.029
regulation of wound healing GO:0061041 2 0.029
neurotransmitter secretion GO:0007269 2 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.028
Human Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.028
Human Zebrafish
neuron projection morphogenesis GO:0048812 161 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
Human
immune system process GO:0002376 241 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
Human Zebrafish
proteasomal protein catabolic process GO:0010498 2 0.028
positive regulation of cellular metabolic process GO:0031325 94 0.028
Human
cellular component morphogenesis GO:0032989 336 0.027
central nervous system development GO:0007417 387 0.027
cellular amine metabolic process GO:0044106 2 0.027
reactive oxygen species metabolic process GO:0072593 6 0.027
cytokinesis GO:0000910 3 0.027
positive regulation of histone modification GO:0031058 1 0.027
cell part morphogenesis GO:0032990 246 0.027
organic acid metabolic process GO:0006082 31 0.027
macromolecule biosynthetic process GO:0009059 227 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.026
rna biosynthetic process GO:0032774 181 0.026
positive regulation of blood circulation GO:1903524 2 0.026
oxoacid metabolic process GO:0043436 31 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.026
Human Zebrafish
positive regulation of secretion by cell GO:1903532 1 0.026
cell projection morphogenesis GO:0048858 244 0.026
response to hexose GO:0009746 3 0.025
negative regulation of multicellular organismal process GO:0051241 69 0.025
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
Human Zebrafish
muscle organ development GO:0007517 101 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
response to external biotic stimulus GO:0043207 97 0.024
locomotion GO:0040011 313 0.024
response to other organism GO:0051707 97 0.024
single organism biosynthetic process GO:0044711 71 0.024
Human Zebrafish
sensory organ development GO:0007423 393 0.024
regulation of rna metabolic process GO:0051252 224 0.024
lipid storage GO:0019915 1 0.024
cellular amino acid metabolic process GO:0006520 7 0.023
protein metabolic process GO:0019538 183 0.023
cellular ketone metabolic process GO:0042180 11 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
sequestering of metal ion GO:0051238 3 0.023
heterocycle metabolic process GO:0046483 290 0.022
Human Zebrafish
gtp metabolic process GO:0046039 4 0.022
cellular component movement GO:0006928 335 0.022
neuron projection development GO:0031175 180 0.022
nitric oxide metabolic process GO:0046209 2 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
multicellular organism growth GO:0035264 4 0.022
Mouse
response to biotic stimulus GO:0009607 97 0.022
negative regulation of biological process GO:0048519 304 0.022
Zebrafish Mouse
angiogenesis GO:0001525 158 0.022
regulation of neurotransmitter transport GO:0051588 1 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.022
regulation of protein transport GO:0051223 3 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
cell cell signaling GO:0007267 52 0.021
cellular protein metabolic process GO:0044267 129 0.021
positive regulation of cell cycle GO:0045787 3 0.021
regulation of calcium ion transport GO:0051924 2 0.021
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.021
peptide transport GO:0015833 1 0.021
blood vessel development GO:0001568 246 0.021
female gonad development GO:0008585 4 0.021
b cell activation GO:0042113 2 0.021
regulation of cell communication GO:0010646 232 0.021
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.021
blood vessel morphogenesis GO:0048514 216 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
positive regulation of gene expression GO:0010628 71 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
brain development GO:0007420 293 0.020
protein secretion GO:0009306 1 0.020
regulation of blood pressure GO:0008217 1 0.019
Mouse
cellular response to chemical stimulus GO:0070887 157 0.019
female sex differentiation GO:0046660 4 0.019
autophagy GO:0006914 4 0.019
mitochondrion organization GO:0007005 4 0.019
cytokinetic process GO:0032506 2 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
endocrine hormone secretion GO:0060986 2 0.019
negative regulation of cellular metabolic process GO:0031324 77 0.019
Zebrafish
regulation of inflammatory response GO:0050727 2 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
gtp catabolic process GO:0006184 2 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
taxis GO:0042330 109 0.019
gastrulation GO:0007369 208 0.019
mononuclear cell proliferation GO:0032943 1 0.019
protein acylation GO:0043543 3 0.018
circulatory system process GO:0003013 87 0.018
Zebrafish Mouse
generation of neurons GO:0048699 385 0.018
defense response GO:0006952 47 0.018
compound eye development GO:0048749 2 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
tube morphogenesis GO:0035239 349 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
regulation of reproductive process GO:2000241 4 0.018
peptide metabolic process GO:0006518 1 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
Human Zebrafish
internal peptidyl lysine acetylation GO:0018393 2 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
positive regulation of catabolic process GO:0009896 4 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
Human Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
Human Zebrafish
meiotic cell cycle process GO:1903046 3 0.018
response to monosaccharide GO:0034284 3 0.018
regulation of neurotransmitter secretion GO:0046928 1 0.018
rna metabolic process GO:0016070 219 0.018
regulation of developmental process GO:0050793 247 0.018
Mouse
antimicrobial humoral response GO:0019730 2 0.018
negative regulation of secretion GO:0051048 2 0.018
determination of bilateral symmetry GO:0009855 204 0.018
carboxylic acid metabolic process GO:0019752 22 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
carbohydrate homeostasis GO:0033500 1 0.017
ion transport GO:0006811 114 0.017
response to glucocorticoid GO:0051384 1 0.017
developmental growth GO:0048589 166 0.017
Mouse
internal protein amino acid acetylation GO:0006475 2 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
positive regulation of cytokine production GO:0001819 2 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
leukocyte proliferation GO:0070661 1 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
lipid catabolic process GO:0016042 4 0.016
regulation of cytokine production GO:0001817 3 0.016
regulation of transcription dna templated GO:0006355 213 0.016
negative regulation of cellular process GO:0048523 283 0.016
Zebrafish
homeostatic process GO:0042592 142 0.016
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
neurological system process GO:0050877 62 0.016
vasculature development GO:0001944 278 0.015
cellular response to external stimulus GO:0071496 2 0.015
regionalization GO:0003002 274 0.015
nuclear transport GO:0051169 4 0.015
chemical homeostasis GO:0048878 49 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
calcium ion transport into cytosol GO:0060402 3 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
specification of symmetry GO:0009799 204 0.015
protein localization to nucleus GO:0034504 3 0.015
meiotic nuclear division GO:0007126 4 0.015
gene expression GO:0010467 252 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
neuron development GO:0048666 262 0.015
regulation of synapse organization GO:0050807 3 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of binding GO:0051098 3 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
protein heterooligomerization GO:0051291 1 0.015
glucose homeostasis GO:0042593 1 0.015
nucleic acid templated transcription GO:0097659 181 0.015
digestive system development GO:0055123 289 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
sodium ion transport GO:0006814 24 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
regulation of autophagy GO:0010506 3 0.015
developmental programmed cell death GO:0010623 4 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
neuroblast proliferation GO:0007405 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
detection of chemical stimulus GO:0009593 4 0.014
negative regulation of defense response GO:0031348 2 0.014
pole plasm assembly GO:0007315 4 0.014
urogenital system development GO:0001655 97 0.014
regulation of protein catabolic process GO:0042176 1 0.014
exocytosis GO:0006887 1 0.014
regulation of response to stimulus GO:0048583 269 0.014
Human
regulation of endocrine process GO:0044060 2 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
Human
positive regulation of cytoskeleton organization GO:0051495 3 0.014
catechol containing compound metabolic process GO:0009712 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
atp catabolic process GO:0006200 4 0.014
response to drug GO:0042493 3 0.014
metal ion transport GO:0030001 58 0.014
negative regulation of metabolic process GO:0009892 86 0.014
Zebrafish
regulation of gtpase activity GO:0043087 2 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
wound healing GO:0042060 90 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
Human
response to corticosteroid GO:0031960 1 0.014
membrane invagination GO:0010324 1 0.014
translational initiation GO:0006413 3 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
response to organic substance GO:0010033 153 0.013
cellular response to nutrient levels GO:0031669 2 0.013
single organism organelle organization GO:1902589 199 0.013
skeletal muscle organ development GO:0060538 78 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
cell projection organization GO:0030030 284 0.013
intracellular mrna localization GO:0008298 1 0.013
post embryonic organ development GO:0048569 4 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
Zebrafish
chemosensory behavior GO:0007635 1 0.013
protein acetylation GO:0006473 2 0.013
protein modification process GO:0036211 100 0.013
regulation of blood vessel size GO:0050880 2 0.013
Mouse
stem cell maintenance GO:0019827 4 0.013
regulation of myotube differentiation GO:0010830 2 0.013
positive regulation of lipid metabolic process GO:0045834 1 0.013
negative regulation of kinase activity GO:0033673 4 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
camera type eye development GO:0043010 222 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of synapse assembly GO:0051963 3 0.013
synaptic transmission GO:0007268 35 0.013
macromolecule modification GO:0043412 111 0.013
cytoplasm organization GO:0007028 4 0.013
tissue regeneration GO:0042246 74 0.013
otolith development GO:0048840 32 0.013
regulation of dendrite development GO:0050773 3 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
regulation of cell development GO:0060284 100 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
cellular response to starvation GO:0009267 1 0.012
positive regulation of immune effector process GO:0002699 3 0.012
small molecule catabolic process GO:0044282 3 0.012
kidney development GO:0001822 92 0.012
response to nutrient GO:0007584 3 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
multi organism process GO:0051704 134 0.012
organelle organization GO:0006996 227 0.012
response to alkaloid GO:0043279 2 0.012
regulation of translational initiation GO:0006446 1 0.012
single organism localization GO:1902578 225 0.012
phagocytosis engulfment GO:0006911 1 0.012
stem cell division GO:0017145 1 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
organonitrogen compound biosynthetic process GO:1901566 47 0.012
Human Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
response to amine GO:0014075 1 0.012
protein import into nucleus GO:0006606 3 0.012
b cell mediated immunity GO:0019724 3 0.012
cellular amide metabolic process GO:0043603 4 0.012
positive regulation of leukocyte mediated immunity GO:0002705 1 0.012
dicarboxylic acid transport GO:0006835 1 0.012
regulation of nervous system development GO:0051960 90 0.012
ion transmembrane transport GO:0034220 91 0.012
positive regulation of epithelial cell migration GO:0010634 2 0.012
axon development GO:0061564 166 0.012
organelle fusion GO:0048284 3 0.012
cellular component disassembly GO:0022411 1 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
protein polymerization GO:0051258 4 0.012
head development GO:0060322 303 0.012
digestive tract development GO:0048565 265 0.012
behavior GO:0007610 74 0.012
Rat
positive regulation of multicellular organismal process GO:0051240 52 0.012
Mouse
immunoglobulin mediated immune response GO:0016064 3 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
monovalent inorganic cation transport GO:0015672 42 0.012
regulation of dna replication GO:0006275 3 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
regulation of sodium ion transport GO:0002028 2 0.011
somatic muscle development GO:0007525 4 0.011
single organism nuclear import GO:1902593 3 0.011
digestive tract morphogenesis GO:0048546 231 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
response to vitamin GO:0033273 3 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
rna localization GO:0006403 4 0.011
positive regulation of wound healing GO:0090303 1 0.011
cellular protein modification process GO:0006464 100 0.011
establishment of localization GO:0051234 244 0.011
leukocyte homeostasis GO:0001776 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of neurogenesis GO:0050767 87 0.011
divalent inorganic cation homeostasis GO:0072507 22 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
cell morphogenesis GO:0000902 289 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
positive regulation of cellular process GO:0048522 201 0.011
Human
lateral line development GO:0048882 66 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
catecholamine metabolic process GO:0006584 2 0.011
immune system development GO:0002520 191 0.011
regulation of leukocyte mediated immunity GO:0002703 1 0.011
embryonic organ development GO:0048568 381 0.011
response to hydrogen peroxide GO:0042542 3 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
multicellular organismal response to stress GO:0033555 2 0.011
lipid homeostasis GO:0055088 3 0.010
muscle cell development GO:0055001 115 0.010
germ line stem cell maintenance GO:0030718 2 0.010
macromolecular complex disassembly GO:0032984 1 0.010
steroid hormone secretion GO:0035929 1 0.010
amino acid transport GO:0006865 2 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
Human
peptidyl serine modification GO:0018209 2 0.010
posterior lateral line development GO:0048916 38 0.010
retina development in camera type eye GO:0060041 146 0.010
cation transport GO:0006812 81 0.010
determination of left right symmetry GO:0007368 179 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
ovulation cycle process GO:0022602 2 0.010
golgi vesicle transport GO:0048193 3 0.010
ion homeostasis GO:0050801 41 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
secondary metabolic process GO:0019748 3 0.010
muscle fiber development GO:0048747 52 0.010
renal system development GO:0072001 94 0.010
pyruvate metabolic process GO:0006090 1 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
negative regulation of mapk cascade GO:0043409 4 0.010

adrb3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
muscular disease DOID:0080000 0 0.012
nervous system disease DOID:863 0 0.010
muscle tissue disease DOID:66 0 0.010