Danio rerio

0 known processes

kbtbd8

kelch repeat and BTB (POZ) domain containing 8

(Aliases: cb672,takrp,MGC152950,zgc:152950,wu:fc57a10,MGC174600)

kbtbd8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 274 0.075
larval development GO:0002164 2 0.073
maintenance of location GO:0051235 4 0.059
nucleocytoplasmic transport GO:0006913 4 0.057
regulation of circadian rhythm GO:0042752 4 0.057
response to chemical GO:0042221 320 0.055
meiosis i GO:0007127 1 0.054
cellular response to extracellular stimulus GO:0031668 2 0.053
cellular component assembly GO:0022607 170 0.052
lipid storage GO:0019915 1 0.051
ubiquitin dependent protein catabolic process GO:0006511 3 0.050
positive regulation of transport GO:0051050 2 0.050
multicellular organism growth GO:0035264 4 0.050
regulation of gene expression GO:0010468 265 0.050
cellular protein catabolic process GO:0044257 4 0.048
negative regulation of chromosome organization GO:2001251 1 0.047
modification dependent protein catabolic process GO:0019941 3 0.047
positive regulation of jun kinase activity GO:0043507 2 0.044
single organism metabolic process GO:0044710 217 0.043
response to stress GO:0006950 263 0.043
cytoplasm organization GO:0007028 4 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.042
positive regulation of map kinase activity GO:0043406 3 0.041
multi organism process GO:0051704 134 0.041
developmental growth GO:0048589 166 0.040
nucleic acid metabolic process GO:0090304 244 0.040
response to external stimulus GO:0009605 264 0.040
striated muscle cell differentiation GO:0051146 129 0.039
aging GO:0007568 2 0.038
negative regulation of biological process GO:0048519 304 0.038
regulation of protein complex assembly GO:0043254 3 0.038
cellular aromatic compound metabolic process GO:0006725 295 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.038
cellular macromolecule metabolic process GO:0044260 391 0.037
regulation of protein catabolic process GO:0042176 1 0.037
regulation of establishment of protein localization GO:0070201 4 0.037
adult behavior GO:0030534 2 0.036
response to abiotic stimulus GO:0009628 122 0.036
convergent extension GO:0060026 118 0.036
purine nucleoside monophosphate catabolic process GO:0009128 4 0.036
phagocytosis engulfment GO:0006911 1 0.035
regulation of meiotic cell cycle GO:0051445 1 0.035
immune system process GO:0002376 241 0.034
alternative mrna splicing via spliceosome GO:0000380 1 0.033
protein heterooligomerization GO:0051291 1 0.033
regulation of primary metabolic process GO:0080090 311 0.033
muscle cell differentiation GO:0042692 139 0.033
pole plasm assembly GO:0007315 4 0.033
regulation of reproductive process GO:2000241 4 0.033
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.032
response to wounding GO:0009611 116 0.032
regulation of mrna splicing via spliceosome GO:0048024 3 0.032
phagocytosis GO:0006909 3 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.032
regulation of mrna processing GO:0050684 3 0.032
positive regulation of cell cycle GO:0045787 3 0.032
membrane invagination GO:0010324 1 0.032
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.031
regulation of biological quality GO:0065008 263 0.031
regulation of protein transport GO:0051223 3 0.031
amine metabolic process GO:0009308 2 0.031
ribonucleoside monophosphate catabolic process GO:0009158 4 0.031
response to drug GO:0042493 3 0.030
response to external biotic stimulus GO:0043207 97 0.030
positive regulation of jnk cascade GO:0046330 3 0.030
single organism localization GO:1902578 225 0.030
response to uv GO:0009411 3 0.029
maternal determination of anterior posterior axis embryo GO:0008358 4 0.029
single organism transport GO:0044765 206 0.029
cellular component biogenesis GO:0044085 178 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.028
response to biotic stimulus GO:0009607 97 0.028
generation of neurons GO:0048699 385 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
protein import GO:0017038 3 0.027
locomotor rhythm GO:0045475 3 0.027
oocyte anterior posterior axis specification GO:0007314 4 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
rna localization GO:0006403 4 0.027
gene expression GO:0010467 252 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
small molecule metabolic process GO:0044281 77 0.026
cartilage development GO:0051216 96 0.026
signal transduction GO:0007165 455 0.026
determination of left right symmetry GO:0007368 179 0.026
cellular component movement GO:0006928 335 0.026
regulation of metabolic process GO:0019222 359 0.026
nucleic acid templated transcription GO:0097659 181 0.026
digestive system development GO:0055123 289 0.026
protein metabolic process GO:0019538 183 0.026
cellular response to external stimulus GO:0071496 2 0.026
circadian sleep wake cycle sleep GO:0050802 1 0.025
positive regulation of catabolic process GO:0009896 4 0.025
chromosome organization involved in meiosis GO:0070192 1 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
germ line stem cell division GO:0042078 1 0.024
inner ear development GO:0048839 126 0.024
cellular response to nutrient levels GO:0031669 2 0.024
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.024
negative regulation of catabolic process GO:0009895 3 0.024
regulation of cell communication GO:0010646 232 0.024
atp catabolic process GO:0006200 4 0.024
negative regulation of autophagy GO:0010507 1 0.024
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
cell morphogenesis GO:0000902 289 0.024
protein import into nucleus GO:0006606 3 0.024
meiotic nuclear division GO:0007126 4 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.023
cellular amine metabolic process GO:0044106 2 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
negative regulation of kinase activity GO:0033673 4 0.023
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.022
regulation of signaling GO:0023051 235 0.022
connective tissue development GO:0061448 99 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
cell part morphogenesis GO:0032990 246 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
digestive tract development GO:0048565 265 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.021
response to nutrient GO:0007584 3 0.021
meiotic cell cycle process GO:1903046 3 0.021
response to organic substance GO:0010033 153 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
cellular response to organic substance GO:0071310 105 0.021
ras protein signal transduction GO:0007265 7 0.021
wnt signaling pathway GO:0016055 80 0.021
growth GO:0040007 174 0.021
negative regulation of response to stimulus GO:0048585 104 0.021
regulation of tube size GO:0035150 2 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
organic substance biosynthetic process GO:1901576 289 0.021
aromatic compound biosynthetic process GO:0019438 217 0.020
pigmentation GO:0043473 85 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
spermatid development GO:0007286 2 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
regulation of cytokine production GO:0001817 3 0.020
negative regulation of signal transduction GO:0009968 94 0.020
circadian sleep wake cycle process GO:0022410 2 0.020
sleep GO:0030431 1 0.020
peptide transport GO:0015833 1 0.019
cellular response to oxygen levels GO:0071453 1 0.019
intracellular signal transduction GO:0035556 85 0.019
response to other organism GO:0051707 97 0.019
oocyte maturation GO:0001556 4 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
tube morphogenesis GO:0035239 349 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
organic acid metabolic process GO:0006082 31 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
spermatid differentiation GO:0048515 2 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
ear development GO:0043583 127 0.019
inorganic ion transmembrane transport GO:0098660 57 0.018
single fertilization GO:0007338 3 0.018
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.018
single organism nuclear import GO:1902593 3 0.018
muscle organ development GO:0007517 101 0.018
regulation of protein targeting GO:1903533 2 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
cellular response to hypoxia GO:0071456 1 0.018
negative regulation of tor signaling GO:0032007 2 0.018
positive regulation of ras protein signal transduction GO:0046579 1 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
cell motility GO:0048870 244 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
pigment cell differentiation GO:0050931 38 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
camera type eye development GO:0043010 222 0.018
cellular ketone metabolic process GO:0042180 11 0.018
cellular protein metabolic process GO:0044267 129 0.017
regulation of binding GO:0051098 3 0.017
response to cadmium ion GO:0046686 14 0.017
regulation of signal transduction GO:0009966 225 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
muscle structure development GO:0061061 196 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
striated muscle tissue development GO:0014706 110 0.017
sister chromatid cohesion GO:0007062 2 0.017
autophagy GO:0006914 4 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
mitochondrion organization GO:0007005 4 0.017
stem cell division GO:0017145 1 0.017
axon development GO:0061564 166 0.017
cellular response to starvation GO:0009267 1 0.017
circadian sleep wake cycle GO:0042745 2 0.016
primary neural tube formation GO:0014020 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
stem cell maintenance GO:0019827 4 0.016
transport GO:0006810 220 0.016
zymogen activation GO:0031638 3 0.016
cell migration GO:0016477 237 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
nuclear import GO:0051170 3 0.016
positive regulation of secretion GO:0051047 1 0.016
establishment of localization GO:0051234 244 0.016
response to vitamin GO:0033273 3 0.016
phosphorus metabolic process GO:0006793 109 0.016
regulation of metal ion transport GO:0010959 4 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
positive regulation of biological process GO:0048518 253 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
regulation of p38mapk cascade GO:1900744 1 0.016
nuclear transport GO:0051169 4 0.016
neuron projection morphogenesis GO:0048812 161 0.016
hormone secretion GO:0046879 2 0.016
organelle assembly GO:0070925 110 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
biosynthetic process GO:0009058 294 0.015
cellular component morphogenesis GO:0032989 336 0.015
regulation of developmental process GO:0050793 247 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
cellular component disassembly GO:0022411 1 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
determination of bilateral symmetry GO:0009855 204 0.015
regulation of autophagy GO:0010506 3 0.015
fertilization GO:0009566 3 0.015
regulation of hormone secretion GO:0046883 2 0.015
segmentation GO:0035282 97 0.015
cell projection morphogenesis GO:0048858 244 0.015
anterior posterior pattern specification GO:0009952 152 0.015
regulation of blood vessel size GO:0050880 2 0.015
cell growth GO:0016049 57 0.015
spindle assembly GO:0051225 2 0.015
pigment granule transport GO:0051904 19 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
antimicrobial humoral response GO:0019730 2 0.015
positive regulation of cellular process GO:0048522 201 0.015
muscle tissue development GO:0060537 110 0.015
regulation of cell activation GO:0050865 1 0.015
central nervous system development GO:0007417 387 0.015
negative regulation of protein import into nucleus GO:0042308 2 0.014
regulation of biosynthetic process GO:0009889 250 0.014
er to golgi vesicle mediated transport GO:0006888 1 0.014
positive regulation of translation GO:0045727 1 0.014
meiotic chromosome segregation GO:0045132 3 0.014
male meiosis GO:0007140 2 0.014
female meiotic division GO:0007143 2 0.014
heterocycle metabolic process GO:0046483 290 0.014
dna templated transcription elongation GO:0006354 3 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
stem cell fate commitment GO:0048865 1 0.014
wound healing GO:0042060 90 0.014
regulation of organelle assembly GO:1902115 4 0.014
chordate embryonic development GO:0043009 271 0.014
regulation of response to nutrient levels GO:0032107 1 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
hormone transport GO:0009914 2 0.014
negative regulation of metabolic process GO:0009892 86 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
cell matrix adhesion GO:0007160 4 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
gtp catabolic process GO:0006184 2 0.013
positive regulation of cell division GO:0051781 2 0.013
fatty acid biosynthetic process GO:0006633 4 0.013
macromolecule modification GO:0043412 111 0.013
rna biosynthetic process GO:0032774 181 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of molecular function GO:0065009 70 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
response to temperature stimulus GO:0009266 15 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
positive regulation of rna biosynthetic process GO:1902680 57 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
lateral inhibition GO:0046331 1 0.013
cellular localization GO:0051641 97 0.013
gtp metabolic process GO:0046039 4 0.013
negative regulation of chromatin modification GO:1903309 1 0.013
oxoacid metabolic process GO:0043436 31 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
behavior GO:0007610 74 0.013
cognition GO:0050890 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
tube closure GO:0060606 1 0.013
neuron differentiation GO:0030182 353 0.013
actin filament polymerization GO:0030041 2 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
regulation of catalytic activity GO:0050790 55 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.012
striated muscle cell development GO:0055002 108 0.012
protein polymerization GO:0051258 4 0.012
negative regulation of ras protein signal transduction GO:0046580 1 0.012
regulation of circadian sleep wake cycle GO:0042749 1 0.012
blood circulation GO:0008015 87 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
defense response GO:0006952 47 0.012
vasculature development GO:0001944 278 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
locomotion GO:0040011 313 0.012
cellular protein modification process GO:0006464 100 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
response to oxygen containing compound GO:1901700 55 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.012
developmental pigmentation GO:0048066 48 0.012
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
macromolecular complex disassembly GO:0032984 1 0.012
protein modification process GO:0036211 100 0.012
catabolic process GO:0009056 32 0.012
positive regulation of multi organism process GO:0043902 3 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
regulation of muscle contraction GO:0006937 3 0.012
positive regulation of cell activation GO:0050867 1 0.012
negative regulation of protein transport GO:0051224 3 0.012
germ line stem cell maintenance GO:0030718 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
gland development GO:0048732 143 0.012
regulation of dna replication GO:0006275 3 0.012
protein stabilization GO:0050821 2 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
negative regulation of translation GO:0017148 1 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
intracellular estrogen receptor signaling pathway GO:0030520 3 0.012
regulation of immune system process GO:0002682 34 0.012
protein localization to nucleus GO:0034504 3 0.012
specification of symmetry GO:0009799 204 0.012
regulation of oocyte development GO:0060281 3 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
skeletal system development GO:0001501 181 0.011
regulation of rna metabolic process GO:0051252 224 0.011
regulation of blood pressure GO:0008217 1 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of cellular component organization GO:0051128 86 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
protein complex disassembly GO:0043241 1 0.011
myofibril assembly GO:0030239 48 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
regulation of cell differentiation GO:0045595 142 0.011
epithelial cell differentiation GO:0030855 116 0.011
circadian rhythm GO:0007623 19 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
tissue remodeling GO:0048771 4 0.011
skeletal muscle organ development GO:0060538 78 0.011
female sex differentiation GO:0046660 4 0.011
embryonic heart tube development GO:0035050 133 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
rna metabolic process GO:0016070 219 0.011
heart development GO:0007507 313 0.011
cellular biosynthetic process GO:0044249 286 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
regulation of cell shape GO:0008360 1 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
glucose homeostasis GO:0042593 1 0.011
pigment granule localization GO:0051875 25 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
negative regulation of cell communication GO:0010648 96 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
p38mapk cascade GO:0038066 1 0.010
cell adhesion mediated by integrin GO:0033627 1 0.010
protein polyubiquitination GO:0000209 4 0.010
regulation of protein polymerization GO:0032271 2 0.010
ameboidal type cell migration GO:0001667 143 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
protein targeting to nucleus GO:0044744 3 0.010
regulation of transcription dna templated GO:0006355 213 0.010
muscle cell development GO:0055001 115 0.010
negative regulation of protein localization to nucleus GO:1900181 2 0.010
developmental cell growth GO:0048588 52 0.010
positive regulation of cellular component biogenesis GO:0044089 3 0.010
heart looping GO:0001947 94 0.010
hemopoiesis GO:0030097 183 0.010
response to inorganic substance GO:0010035 38 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
regulation of cell size GO:0008361 29 0.010
eye development GO:0001654 277 0.010
regulation of inflammatory response GO:0050727 2 0.010
sex determination GO:0007530 1 0.010
hepaticobiliary system development GO:0061008 98 0.010
response to metal ion GO:0010038 34 0.010

kbtbd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
disease of cellular proliferation DOID:14566 0 0.010