Danio rerio

0 known processes

lrrfip1a

leucine rich repeat (in FLII) interacting protein 1a

(Aliases: wu:fc06b04,zeh1367,hm:zeh1367,wu:fi15c07,lrrfip1)

lrrfip1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 196 0.477
chemosensory behavior GO:0007635 1 0.305
cell projection assembly GO:0030031 64 0.241
cellular component assembly involved in morphogenesis GO:0010927 107 0.208
signal transduction GO:0007165 455 0.192
regulation of cellular metabolic process GO:0031323 320 0.139
cellular component assembly GO:0022607 170 0.138
cellular component biogenesis GO:0044085 178 0.133
cellular macromolecule metabolic process GO:0044260 391 0.120
cellular biosynthetic process GO:0044249 286 0.094
regulation of response to stimulus GO:0048583 269 0.094
phagocytosis GO:0006909 3 0.092
larval development GO:0002164 2 0.091
response to chemical GO:0042221 320 0.091
nitrogen compound metabolic process GO:0006807 319 0.084
meiotic nuclear division GO:0007126 4 0.080
aging GO:0007568 2 0.079
cell surface receptor signaling pathway GO:0007166 325 0.075
maintenance of location GO:0051235 4 0.073
cellular aromatic compound metabolic process GO:0006725 295 0.072
regulation of metabolic process GO:0019222 359 0.071
regulation of biosynthetic process GO:0009889 250 0.068
nucleic acid metabolic process GO:0090304 244 0.067
regulation of nitrogen compound metabolic process GO:0051171 251 0.064
cognition GO:0050890 1 0.063
regulation of macromolecule metabolic process GO:0060255 317 0.063
cytoskeleton organization GO:0007010 96 0.062
response to external stimulus GO:0009605 264 0.062
cellular amine metabolic process GO:0044106 2 0.061
heterocycle metabolic process GO:0046483 290 0.060
cell substrate adhesion GO:0031589 4 0.060
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.059
locomotion GO:0040011 313 0.058
organelle organization GO:0006996 227 0.057
phosphorus metabolic process GO:0006793 109 0.055
germ line stem cell maintenance GO:0030718 2 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.053
positive regulation of cell cycle GO:0045787 3 0.053
regulation of biological quality GO:0065008 263 0.052
cell morphogenesis GO:0000902 289 0.050
nucleobase containing compound metabolic process GO:0006139 274 0.050
regulation of cell substrate adhesion GO:0010810 1 0.049
organonitrogen compound metabolic process GO:1901564 74 0.049
cilium organization GO:0044782 71 0.048
cell part morphogenesis GO:0032990 246 0.048
modification dependent protein catabolic process GO:0019941 3 0.048
single organism transport GO:0044765 206 0.047
positive regulation of transport GO:0051050 2 0.047
response to abiotic stimulus GO:0009628 122 0.047
cellular ketone metabolic process GO:0042180 11 0.047
phosphate containing compound metabolic process GO:0006796 108 0.046
lipid storage GO:0019915 1 0.045
neuron differentiation GO:0030182 353 0.045
amine metabolic process GO:0009308 2 0.045
system process GO:0003008 185 0.045
fertilization GO:0009566 3 0.045
single fertilization GO:0007338 3 0.045
small molecule metabolic process GO:0044281 77 0.044
cell projection organization GO:0030030 284 0.044
pyruvate metabolic process GO:0006090 1 0.044
regulation of circadian rhythm GO:0042752 4 0.044
adult behavior GO:0030534 2 0.043
embryonic organ morphogenesis GO:0048562 274 0.043
negative regulation of biological process GO:0048519 304 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.042
positive regulation of biological process GO:0048518 253 0.042
macromolecule biosynthetic process GO:0009059 227 0.042
cellular component morphogenesis GO:0032989 336 0.042
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.041
cellular protein metabolic process GO:0044267 129 0.040
organic substance biosynthetic process GO:1901576 289 0.039
spermatid development GO:0007286 2 0.039
organelle assembly GO:0070925 110 0.039
negative regulation of cellular process GO:0048523 283 0.038
intracellular signal transduction GO:0035556 85 0.038
actin polymerization or depolymerization GO:0008154 2 0.038
ubiquitin dependent protein catabolic process GO:0006511 3 0.038
regulation of cellular amine metabolic process GO:0033238 0 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.038
regulation of reproductive process GO:2000241 4 0.037
muscle cell development GO:0055001 115 0.037
organic cyclic compound metabolic process GO:1901360 301 0.037
chordate embryonic development GO:0043009 271 0.037
negative regulation of protein complex assembly GO:0031333 1 0.036
regulation of primary metabolic process GO:0080090 311 0.036
regulation of signal transduction GO:0009966 225 0.036
regulation of signaling GO:0023051 235 0.036
long chain fatty acid metabolic process GO:0001676 1 0.036
phagocytosis engulfment GO:0006911 1 0.036
muscle organ development GO:0007517 101 0.035
muscle cell differentiation GO:0042692 139 0.035
multicellular organism growth GO:0035264 4 0.035
organic cyclic compound biosynthetic process GO:1901362 223 0.035
neurotransmitter secretion GO:0007269 2 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
regulation of cell projection assembly GO:0060491 4 0.034
cellular response to chemical stimulus GO:0070887 157 0.034
calcium mediated signaling GO:0019722 2 0.034
alpha amino acid metabolic process GO:1901605 3 0.034
neurological system process GO:0050877 62 0.033
proteasomal protein catabolic process GO:0010498 2 0.033
sleep GO:0030431 1 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
spermatid differentiation GO:0048515 2 0.033
biosynthetic process GO:0009058 294 0.032
regulation of nucleotide catabolic process GO:0030811 2 0.032
cellular response to organic substance GO:0071310 105 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
response to endogenous stimulus GO:0009719 83 0.031
regulation of mrna splicing via spliceosome GO:0048024 3 0.031
female meiotic division GO:0007143 2 0.031
regulation of cell matrix adhesion GO:0001952 1 0.030
cellular response to endogenous stimulus GO:0071495 68 0.030
fatty acid transport GO:0015908 1 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
organic acid metabolic process GO:0006082 31 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.029
negative regulation of synapse assembly GO:0051964 2 0.029
neurotransmitter transport GO:0006836 2 0.029
response to organic substance GO:0010033 153 0.029
regulation of cell activation GO:0050865 1 0.029
oxoacid metabolic process GO:0043436 31 0.028
generation of neurons GO:0048699 385 0.028
striated muscle cell development GO:0055002 108 0.028
enzyme linked receptor protein signaling pathway GO:0007167 106 0.028
regulation of blood pressure GO:0008217 1 0.028
aromatic compound biosynthetic process GO:0019438 217 0.028
regulation of gtp catabolic process GO:0033124 2 0.027
cardiac conduction system development GO:0003161 1 0.027
somitogenesis GO:0001756 87 0.027
regulation of cell shape GO:0008360 1 0.027
regulation of neural precursor cell proliferation GO:2000177 3 0.027
regulation of protein polymerization GO:0032271 2 0.027
cellular response to hormone stimulus GO:0032870 39 0.027
growth GO:0040007 174 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
protein metabolic process GO:0019538 183 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.026
developmental growth GO:0048589 166 0.026
determination of left right symmetry GO:0007368 179 0.026
establishment of localization GO:0051234 244 0.026
regulation of cell communication GO:0010646 232 0.026
inorganic cation transmembrane transport GO:0098662 50 0.026
cellular protein modification process GO:0006464 100 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
gtp metabolic process GO:0046039 4 0.025
gastrulation GO:0007369 208 0.025
protein modification process GO:0036211 100 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
regulation of cellular protein metabolic process GO:0032268 52 0.024
regulation of ion transmembrane transporter activity GO:0032412 2 0.024
single organism metabolic process GO:0044710 217 0.024
negative regulation of signaling GO:0023057 96 0.024
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.024
regulation of neurotransmitter secretion GO:0046928 1 0.023
rna metabolic process GO:0016070 219 0.023
embryonic organ development GO:0048568 381 0.023
circadian sleep wake cycle process GO:0022410 2 0.023
regulation of dendrite development GO:0050773 3 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.022
neuron neuron synaptic transmission GO:0007270 1 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
gene expression GO:0010467 252 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
cardiac muscle tissue development GO:0048738 48 0.022
regulation of membrane potential GO:0042391 23 0.022
determination of bilateral symmetry GO:0009855 204 0.022
catechol containing compound metabolic process GO:0009712 2 0.022
cellular protein catabolic process GO:0044257 4 0.022
cilium assembly GO:0042384 58 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.021
regulation of binding GO:0051098 3 0.021
synaptic vesicle localization GO:0097479 1 0.021
muscle fiber development GO:0048747 52 0.021
transport GO:0006810 220 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
cilium morphogenesis GO:0060271 85 0.021
digestive tract morphogenesis GO:0048546 231 0.021
single organism biosynthetic process GO:0044711 71 0.021
cellular response to extracellular stimulus GO:0031668 2 0.020
regulation of myotube differentiation GO:0010830 2 0.020
phosphorylation GO:0016310 69 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
cell matrix adhesion GO:0007160 4 0.020
protein polymerization GO:0051258 4 0.020
long chain fatty acid transport GO:0015909 1 0.020
macromolecule modification GO:0043412 111 0.020
positive regulation of multi organism process GO:0043902 3 0.020
positive regulation of cell adhesion GO:0045785 1 0.019
neuron development GO:0048666 262 0.019
muscle tissue development GO:0060537 110 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
entrainment of circadian clock by photoperiod GO:0043153 1 0.019
organophosphate biosynthetic process GO:0090407 23 0.019
specification of symmetry GO:0009799 204 0.019
synaptic vesicle transport GO:0048489 1 0.019
alternative mrna splicing via spliceosome GO:0000380 1 0.019
axon development GO:0061564 166 0.019
striated muscle cell differentiation GO:0051146 129 0.019
actin cytoskeleton organization GO:0030036 63 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
regulation of cellular component organization GO:0051128 86 0.019
inorganic ion transmembrane transport GO:0098660 57 0.018
negative regulation of phosphate metabolic process GO:0045936 13 0.018
ganglioside metabolic process GO:0001573 3 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
cellular lipid catabolic process GO:0044242 3 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.018
somatic muscle development GO:0007525 4 0.018
plasma membrane repair GO:0001778 2 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
small molecule catabolic process GO:0044282 3 0.018
regulation of filopodium assembly GO:0051489 2 0.018
rna biosynthetic process GO:0032774 181 0.017
leukocyte proliferation GO:0070661 1 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
response to carbohydrate GO:0009743 3 0.017
regulation of skeletal muscle tissue development GO:0048641 4 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
multicellular organismal response to stress GO:0033555 2 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
regulation of natural killer cell mediated immunity GO:0002715 1 0.017
heart looping GO:0001947 94 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
skeletal muscle tissue development GO:0007519 67 0.017
carbohydrate homeostasis GO:0033500 1 0.017
blood circulation GO:0008015 87 0.017
negative regulation of secretion GO:0051048 2 0.017
sequestering of metal ion GO:0051238 3 0.017
stem cell maintenance GO:0019827 4 0.017
cell projection morphogenesis GO:0048858 244 0.017
single organism localization GO:1902578 225 0.017
protein phosphorylation GO:0006468 47 0.017
neuron projection development GO:0031175 180 0.017
positive regulation of cellular process GO:0048522 201 0.017
regulation of receptor activity GO:0010469 2 0.016
negative regulation of metabolic process GO:0009892 86 0.016
cell aging GO:0007569 2 0.016
single organism organelle organization GO:1902589 199 0.016
insulin like growth factor receptor signaling pathway GO:0048009 4 0.016
response to antibiotic GO:0046677 1 0.016
amino acid transport GO:0006865 2 0.016
response to oxygen containing compound GO:1901700 55 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
cellular lipid metabolic process GO:0044255 36 0.016
cellular aldehyde metabolic process GO:0006081 4 0.016
positive regulation of cell activation GO:0050867 1 0.016
response to glucose GO:0009749 3 0.015
regulation of gene expression GO:0010468 265 0.015
regulation of transporter activity GO:0032409 2 0.015
striated muscle tissue development GO:0014706 110 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
cardiac chamber formation GO:0003207 4 0.015
cellular response to external stimulus GO:0071496 2 0.015
organonitrogen compound biosynthetic process GO:1901566 47 0.015
regulation of transcription dna templated GO:0006355 213 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
response to hormone GO:0009725 48 0.015
nucleic acid templated transcription GO:0097659 181 0.015
negative regulation of cell communication GO:0010648 96 0.014
regulation of cardiac muscle tissue development GO:0055024 1 0.014
regulation of cardiac muscle contraction GO:0055117 2 0.014
regulation of synapse assembly GO:0051963 3 0.014
regulation of protein binding GO:0043393 3 0.014
convergent extension GO:0060026 118 0.014
taxis GO:0042330 109 0.014
positive regulation of reproductive process GO:2000243 2 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
cardiac muscle fiber development GO:0048739 3 0.014
behavior GO:0007610 74 0.014
adherens junction organization GO:0034332 4 0.014
regulation of localization GO:0032879 104 0.014
negative regulation of cellular biosynthetic process GO:0031327 55 0.014
lamellipodium assembly GO:0030032 1 0.014
cellular response to starvation GO:0009267 1 0.014
transmission of nerve impulse GO:0019226 19 0.014
negative regulation of neural precursor cell proliferation GO:2000178 1 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
cellular response to organic cyclic compound GO:0071407 38 0.013
lymphocyte proliferation GO:0046651 1 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
anion transport GO:0006820 38 0.013
actomyosin structure organization GO:0031032 53 0.013
cardiac ventricle formation GO:0003211 1 0.013
regulation of synapse organization GO:0050807 3 0.013
axonogenesis GO:0007409 152 0.013
cellular response to nutrient levels GO:0031669 2 0.013
transmembrane transport GO:0055085 120 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
stem cell proliferation GO:0072089 4 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of muscle contraction GO:0006937 3 0.012
polyol metabolic process GO:0019751 1 0.012
monocyte differentiation GO:0030224 2 0.012
carbohydrate derivative metabolic process GO:1901135 61 0.012
cation transmembrane transport GO:0098655 65 0.012
actin filament polymerization GO:0030041 2 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
regulation of organelle organization GO:0033043 29 0.012
organism emergence from protective structure GO:0071684 4 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
gtp catabolic process GO:0006184 2 0.012
response to hexose GO:0009746 3 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
lymphatic endothelial cell fate commitment GO:0060838 1 0.012
smooth muscle contraction GO:0006939 2 0.012
cell cycle arrest GO:0007050 1 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
somite development GO:0061053 96 0.012
regulation of nervous system development GO:0051960 90 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
regulation of mrna processing GO:0050684 3 0.012
membrane organization GO:0061024 21 0.012
mrna metabolic process GO:0016071 20 0.012
regulation of neurotransmitter transport GO:0051588 1 0.011
dicarboxylic acid transport GO:0006835 1 0.011
regulation of cellular component movement GO:0051270 55 0.011
cardiac atrium morphogenesis GO:0003209 2 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
transcription dna templated GO:0006351 181 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
endothelial cell fate commitment GO:0060839 3 0.011
response to glucocorticoid GO:0051384 1 0.011
regulation of rna metabolic process GO:0051252 224 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
regulation of neurogenesis GO:0050767 87 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of tube size GO:0035150 2 0.011
negative regulation of phosphorus metabolic process GO:0010563 13 0.011
regulation of lyase activity GO:0051339 12 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
protein modification by small protein removal GO:0070646 1 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
regulation of developmental process GO:0050793 247 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
positive regulation of catabolic process GO:0009896 4 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
homeostatic process GO:0042592 142 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
response to food GO:0032094 1 0.011
response to stress GO:0006950 263 0.011
regulation of gtpase activity GO:0043087 2 0.011
dna templated transcription elongation GO:0006354 3 0.010
regulation of catalytic activity GO:0050790 55 0.010
response to amphetamine GO:0001975 1 0.010
heart development GO:0007507 313 0.010
regulation of protein metabolic process GO:0051246 56 0.010
mechanosensory behavior GO:0007638 2 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
circadian sleep wake cycle GO:0042745 2 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
positive regulation of oocyte development GO:0060282 1 0.010
negative regulation of developmental process GO:0051093 65 0.010
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.010
cell proliferation GO:0008283 80 0.010
action potential GO:0001508 19 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
regulation of metal ion transport GO:0010959 4 0.010
nuclear import GO:0051170 3 0.010
lamellipodium organization GO:0097581 1 0.010
regulation of molecular function GO:0065009 70 0.010
lymphocyte homeostasis GO:0002260 1 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010

lrrfip1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
hypertrophic cardiomyopathy DOID:11984 0 0.047
myopathy DOID:423 0 0.047
muscular disease DOID:0080000 0 0.047
heart disease DOID:114 0 0.047
cardiomyopathy DOID:0050700 0 0.047
intrinsic cardiomyopathy DOID:0060036 0 0.047
cardiovascular system disease DOID:1287 0 0.047
musculoskeletal system disease DOID:17 0 0.047
muscle tissue disease DOID:66 0 0.047
nervous system disease DOID:863 0 0.023
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014