Danio rerio

0 known processes

zgc:112303

zgc:112303

(Aliases: tmx4,MGC112303,im:6891941)

zgc:112303 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.075
cellular protein catabolic process GO:0044257 4 0.051
aging GO:0007568 2 0.051
maintenance of location GO:0051235 4 0.042
positive regulation of transport GO:0051050 2 0.042
multicellular organism growth GO:0035264 4 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.040
modification dependent protein catabolic process GO:0019941 3 0.040
nitrogen compound metabolic process GO:0006807 319 0.039
cellular macromolecule metabolic process GO:0044260 391 0.038
establishment of protein localization to organelle GO:0072594 4 0.038
ubiquitin dependent protein catabolic process GO:0006511 3 0.038
modification dependent macromolecule catabolic process GO:0043632 3 0.038
phagocytosis GO:0006909 3 0.035
proteasomal protein catabolic process GO:0010498 2 0.035
nucleocytoplasmic transport GO:0006913 4 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
heterocycle metabolic process GO:0046483 290 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
signal transduction GO:0007165 455 0.032
amine metabolic process GO:0009308 2 0.031
nuclear transport GO:0051169 4 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
lipid storage GO:0019915 1 0.031
cellular amine metabolic process GO:0044106 2 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.030
meiotic nuclear division GO:0007126 4 0.030
regulation of primary metabolic process GO:0080090 311 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
regulation of metabolic process GO:0019222 359 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
cellular aromatic compound metabolic process GO:0006725 295 0.029
regulation of establishment of protein localization GO:0070201 4 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
gtp catabolic process GO:0006184 2 0.028
stem cell maintenance GO:0019827 4 0.028
regulation of protein catabolic process GO:0042176 1 0.028
positive regulation of catabolic process GO:0009896 4 0.028
gtp metabolic process GO:0046039 4 0.027
regulation of protein transport GO:0051223 3 0.027
cellular biosynthetic process GO:0044249 286 0.027
cytokinesis GO:0000910 3 0.027
regulation of mrna processing GO:0050684 3 0.027
gene expression GO:0010467 252 0.026
rna metabolic process GO:0016070 219 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
regulation of mrna splicing via spliceosome GO:0048024 3 0.026
biosynthetic process GO:0009058 294 0.026
single organism nuclear import GO:1902593 3 0.026
organic substance biosynthetic process GO:1901576 289 0.026
response to drug GO:0042493 3 0.026
protein localization to plasma membrane GO:0072659 1 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.025
regulation of response to stimulus GO:0048583 269 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
cell morphogenesis GO:0000902 289 0.024
cellular component morphogenesis GO:0032989 336 0.024
regulation of protein complex assembly GO:0043254 3 0.024
response to chemical GO:0042221 320 0.024
positive regulation of cell cycle GO:0045787 3 0.024
protein localization to nucleus GO:0034504 3 0.024
regulation of cell shape GO:0008360 1 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
mitochondrion organization GO:0007005 4 0.024
macromolecule biosynthetic process GO:0009059 227 0.024
regulation of cytokine production GO:0001817 3 0.024
nuclear import GO:0051170 3 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
rna localization GO:0006403 4 0.023
protein import into nucleus GO:0006606 3 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
cellular ketone metabolic process GO:0042180 11 0.023
regulation of binding GO:0051098 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
establishment of localization GO:0051234 244 0.022
membrane fusion GO:0061025 2 0.022
negative regulation of biological process GO:0048519 304 0.022
golgi vesicle transport GO:0048193 3 0.022
regulation of gene expression GO:0010468 265 0.022
protein import GO:0017038 3 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
nucleic acid metabolic process GO:0090304 244 0.022
nucleic acid templated transcription GO:0097659 181 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.022
positive regulation of cell adhesion GO:0045785 1 0.022
transport GO:0006810 220 0.022
single organism metabolic process GO:0044710 217 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
organonitrogen compound metabolic process GO:1901564 74 0.021
protein targeting to nucleus GO:0044744 3 0.021
regulation of biological quality GO:0065008 263 0.021
endosomal transport GO:0016197 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
meiotic cell cycle process GO:1903046 3 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
small molecule metabolic process GO:0044281 77 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
regulation of protein targeting GO:1903533 2 0.021
negative regulation of cellular process GO:0048523 283 0.021
regulation of protein ubiquitination GO:0031396 3 0.020
single organism membrane fusion GO:0044801 2 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
central nervous system development GO:0007417 387 0.020
rna biosynthetic process GO:0032774 181 0.020
sensory organ development GO:0007423 393 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
neuron differentiation GO:0030182 353 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
transcription dna templated GO:0006351 181 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
cellular amino acid metabolic process GO:0006520 7 0.019
response to uv GO:0009411 3 0.019
regulation of signal transduction GO:0009966 225 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
regulation of developmental process GO:0050793 247 0.019
protein metabolic process GO:0019538 183 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
meiotic chromosome segregation GO:0045132 3 0.019
organelle fusion GO:0048284 3 0.019
cell part morphogenesis GO:0032990 246 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
organelle organization GO:0006996 227 0.019
cellular component disassembly GO:0022411 1 0.019
positive regulation of notch signaling pathway GO:0045747 3 0.019
stem cell proliferation GO:0072089 4 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
localization of cell GO:0051674 244 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
protein acylation GO:0043543 3 0.019
locomotor rhythm GO:0045475 3 0.019
phagocytosis engulfment GO:0006911 1 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
oxoacid metabolic process GO:0043436 31 0.019
regulation of cell activation GO:0050865 1 0.018
regulation of cell communication GO:0010646 232 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
cellular component movement GO:0006928 335 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
regulation of biosynthetic process GO:0009889 250 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
cognition GO:0050890 1 0.018
positive regulation of cytokine production GO:0001819 2 0.018
female sex differentiation GO:0046660 4 0.018
response to stress GO:0006950 263 0.018
actin filament polymerization GO:0030041 2 0.018
head development GO:0060322 303 0.018
cellular response to nutrient levels GO:0031669 2 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
regulation of protein polymerization GO:0032271 2 0.018
regulation of signaling GO:0023051 235 0.018
response to external stimulus GO:0009605 264 0.018
regulation of rna metabolic process GO:0051252 224 0.018
alternative mrna splicing via spliceosome GO:0000380 1 0.018
cell matrix adhesion GO:0007160 4 0.018
protein acetylation GO:0006473 2 0.018
cell projection morphogenesis GO:0048858 244 0.018
positive regulation of secretion GO:0051047 1 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
cellular response to starvation GO:0009267 1 0.017
spermatid development GO:0007286 2 0.017
neuron development GO:0048666 262 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
cellular protein metabolic process GO:0044267 129 0.017
protein secretion GO:0009306 1 0.017
positive regulation of translation GO:0045727 1 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
organic acid metabolic process GO:0006082 31 0.017
peptidyl serine modification GO:0018209 2 0.017
exocytosis GO:0006887 1 0.017
cell projection organization GO:0030030 284 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
single organism transport GO:0044765 206 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
single organism localization GO:1902578 225 0.016
autophagy GO:0006914 4 0.016
membrane invagination GO:0010324 1 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
cellular response to radiation GO:0071478 4 0.016
cellular respiration GO:0045333 3 0.016
single organism organelle organization GO:1902589 199 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
protein polymerization GO:0051258 4 0.016
protein complex disassembly GO:0043241 1 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
regulation of synapse organization GO:0050807 3 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
macroautophagy GO:0016236 1 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
leukocyte proliferation GO:0070661 1 0.015
rna transport GO:0050658 2 0.015
macromolecular complex disassembly GO:0032984 1 0.015
cellular amide metabolic process GO:0043603 4 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
nuclear export GO:0051168 1 0.015
antimicrobial humoral response GO:0019730 2 0.015
cell substrate adhesion GO:0031589 4 0.015
positive regulation of cell activation GO:0050867 1 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of gtpase activity GO:0043087 2 0.015
brain development GO:0007420 293 0.015
locomotion GO:0040011 313 0.015
growth GO:0040007 174 0.015
cell migration GO:0016477 237 0.015
double strand break repair GO:0006302 3 0.015
regulation of transcription dna templated GO:0006355 213 0.015
eye development GO:0001654 277 0.015
centrosome organization GO:0051297 1 0.015
spermatid differentiation GO:0048515 2 0.015
protein dephosphorylation GO:0006470 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
tube morphogenesis GO:0035239 349 0.015
female gonad development GO:0008585 4 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
regulation of chromosome segregation GO:0051983 1 0.015
nucleic acid transport GO:0050657 2 0.015
cell motility GO:0048870 244 0.015
response to organic substance GO:0010033 153 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
b cell activation GO:0042113 2 0.014
negative regulation of catabolic process GO:0009895 3 0.014
regulation of synapse assembly GO:0051963 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
tissue remodeling GO:0048771 4 0.014
heart development GO:0007507 313 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
response to topologically incorrect protein GO:0035966 2 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
stem cell division GO:0017145 1 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
determination of bilateral symmetry GO:0009855 204 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
synaptic vesicle transport GO:0048489 1 0.014
generation of neurons GO:0048699 385 0.014
immune system process GO:0002376 241 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
response to hexose GO:0009746 3 0.014
vasculature development GO:0001944 278 0.014
neuroblast proliferation GO:0007405 2 0.014
wnt signaling pathway GO:0016055 80 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
regulation of organelle assembly GO:1902115 4 0.014
regulation of autophagy GO:0010506 3 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
protein polyubiquitination GO:0000209 4 0.014
positive regulation of biological process GO:0048518 253 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
cellular component assembly GO:0022607 170 0.013
germ line stem cell maintenance GO:0030718 2 0.013
system process GO:0003008 185 0.013
mononuclear cell proliferation GO:0032943 1 0.013
dna templated transcription elongation GO:0006354 3 0.013
positive regulation of cellular process GO:0048522 201 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
secondary metabolic process GO:0019748 3 0.013
regionalization GO:0003002 274 0.013
translational initiation GO:0006413 3 0.013
cellular protein modification process GO:0006464 100 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
embryonic organ development GO:0048568 381 0.013
chemosensory behavior GO:0007635 1 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
adult behavior GO:0030534 2 0.013
peptide transport GO:0015833 1 0.013
macromolecule modification GO:0043412 111 0.013
positive regulation of immune effector process GO:0002699 3 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
protein modification process GO:0036211 100 0.013
specification of symmetry GO:0009799 204 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
regulation of inflammatory response GO:0050727 2 0.013
gland development GO:0048732 143 0.013
compound eye development GO:0048749 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
cellular response to light stimulus GO:0071482 4 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of reproductive process GO:2000241 4 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
response to monosaccharide GO:0034284 3 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
sequestering of metal ion GO:0051238 3 0.012
cellular response to organic substance GO:0071310 105 0.012
liver development GO:0001889 96 0.012
synaptic vesicle localization GO:0097479 1 0.012
single fertilization GO:0007338 3 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
developmental programmed cell death GO:0010623 4 0.012
lamellipodium assembly GO:0030032 1 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
female meiotic division GO:0007143 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of metal ion transport GO:0010959 4 0.012
viral process GO:0016032 1 0.012
atp catabolic process GO:0006200 4 0.012
negative regulation of protein transport GO:0051224 3 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
axon development GO:0061564 166 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
cell death GO:0008219 121 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
homeostatic process GO:0042592 142 0.012
establishment of rna localization GO:0051236 3 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
negative regulation of metabolic process GO:0009892 86 0.012
camera type eye development GO:0043010 222 0.012
microtubule organizing center organization GO:0031023 1 0.012
nucleobase containing compound transport GO:0015931 2 0.012
negative regulation of cytokine production GO:0001818 1 0.012
regulation of cell projection assembly GO:0060491 4 0.012
response to carbohydrate GO:0009743 3 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
protein stabilization GO:0050821 2 0.011
intracellular signal transduction GO:0035556 85 0.011
tube closure GO:0060606 1 0.011
response to biotic stimulus GO:0009607 97 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of muscle contraction GO:0006937 3 0.011
developmental growth GO:0048589 166 0.011
regulation of cellular component organization GO:0051128 86 0.011
interspecies interaction between organisms GO:0044419 4 0.011
primary neural tube formation GO:0014020 1 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
cilium morphogenesis GO:0060271 85 0.011
somatic stem cell maintenance GO:0035019 1 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
neurotransmitter transport GO:0006836 2 0.011
carbohydrate homeostasis GO:0033500 1 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
adherens junction organization GO:0034332 4 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
protein homooligomerization GO:0051260 3 0.011
cell substrate junction assembly GO:0007044 2 0.011
negative regulation of defense response GO:0031348 2 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
response to unfolded protein GO:0006986 2 0.011
lamellipodium organization GO:0097581 1 0.011
histone h3 k4 methylation GO:0051568 2 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
regulation of blood pressure GO:0008217 1 0.011
fertilization GO:0009566 3 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
mitotic cytokinesis GO:0000281 3 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
vacuolar transport GO:0007034 2 0.011
glucose homeostasis GO:0042593 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
blood vessel development GO:0001568 246 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
regulation of jak stat cascade GO:0046425 3 0.011
somatic muscle development GO:0007525 4 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
meiosis i GO:0007127 1 0.011
death GO:0016265 121 0.011
activation of mapk activity GO:0000187 3 0.011
apoptotic process GO:0006915 116 0.011
inositol lipid mediated signaling GO:0048017 2 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
regulation of dna replication GO:0006275 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
sensory organ morphogenesis GO:0090596 200 0.010
cytokinetic process GO:0032506 2 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
gastrulation GO:0007369 208 0.010
hemopoiesis GO:0030097 183 0.010
positive regulation of jun kinase activity GO:0043507 2 0.010
cell cycle arrest GO:0007050 1 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
immune system development GO:0002520 191 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
response to hydrogen peroxide GO:0042542 3 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
axonogenesis GO:0007409 152 0.010
regulation of protein binding GO:0043393 3 0.010
positive regulation of histone modification GO:0031058 1 0.010
negative regulation of chromosome organization GO:2001251 1 0.010

zgc:112303 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
cardiovascular system disease DOID:1287 0 0.014
disease of metabolism DOID:0014667 0 0.013
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.010