Danio rerio

35 known processes

pdzd7a

PDZ domain containing 7a

(Aliases: si:dkey-158p2.1)

pdzd7a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.655
synaptic vesicle transport GO:0048489 1 0.623
photoreceptor cell differentiation GO:0046530 55 0.586
establishment of vesicle localization GO:0051650 24 0.454
neuron development GO:0048666 262 0.364
neurotransmitter transport GO:0006836 2 0.280
cellular pigmentation GO:0033059 30 0.253
eye photoreceptor cell development GO:0042462 30 0.240
establishment of synaptic vesicle localization GO:0097480 1 0.240
regulation of biological quality GO:0065008 263 0.237
single organism localization GO:1902578 225 0.234
synaptic vesicle localization GO:0097479 1 0.228
neuron neuron synaptic transmission GO:0007270 1 0.200
eye photoreceptor cell differentiation GO:0001754 45 0.199
determination of left right symmetry GO:0007368 179 0.190
establishment of localization GO:0051234 244 0.170
amino acid transport GO:0006865 2 0.169
neurotransmitter secretion GO:0007269 2 0.159
neuromuscular process controlling balance GO:0050885 3 0.153
single organism transport GO:0044765 206 0.152
microtubule based movement GO:0007018 33 0.141
generation of neurons GO:0048699 385 0.135
regulation of multicellular organism growth GO:0040014 4 0.129
maintenance of location GO:0051235 4 0.129
sensory perception of smell GO:0007608 2 0.128
cytokinesis GO:0000910 3 0.122
neuron projection development GO:0031175 180 0.108
multicellular organism growth GO:0035264 4 0.107
eye morphogenesis GO:0048592 144 0.101
synaptic transmission GO:0007268 35 0.100
negative regulation of biological process GO:0048519 304 0.098
positive regulation of cellular component biogenesis GO:0044089 3 0.097
pigment granule transport GO:0051904 19 0.096
establishment of organelle localization GO:0051656 45 0.094
system process GO:0003008 185 0.093
photoreceptor cell outer segment organization GO:0035845 9 0.089
regulation of multicellular organismal process GO:0051239 277 0.088
eye development GO:0001654 277 0.087
organelle localization GO:0051640 49 0.086
photoreceptor cell development GO:0042461 40 0.085
reflex GO:0060004 2 0.084
transport GO:0006810 220 0.084
cellular response to radiation GO:0071478 4 0.083
cilium organization GO:0044782 71 0.083
exocytosis GO:0006887 1 0.080
vesicle localization GO:0051648 27 0.079
regulation of reproductive process GO:2000241 4 0.078
regulation of cell projection assembly GO:0060491 4 0.078
protein localization to nucleus GO:0034504 3 0.076
detection of abiotic stimulus GO:0009582 24 0.076
negative regulation of reproductive process GO:2000242 3 0.073
regulation of systemic arterial blood pressure GO:0003073 1 0.072
transmembrane transport GO:0055085 120 0.071
neuron differentiation GO:0030182 353 0.071
ion transmembrane transport GO:0034220 91 0.069
dicarboxylic acid transport GO:0006835 1 0.064
signal transduction GO:0007165 455 0.063
tube morphogenesis GO:0035239 349 0.062
cognition GO:0050890 1 0.061
cation transmembrane transport GO:0098655 65 0.060
regulation of metabolic process GO:0019222 359 0.059
retina homeostasis GO:0001895 12 0.059
regulation of response to nutrient levels GO:0032107 1 0.059
sensory perception of chemical stimulus GO:0007606 3 0.058
locomotion GO:0040011 313 0.057
positive regulation of biological process GO:0048518 253 0.056
specification of symmetry GO:0009799 204 0.055
homeostatic process GO:0042592 142 0.054
cell cell signaling GO:0007267 52 0.054
heterocycle metabolic process GO:0046483 290 0.053
embryonic organ development GO:0048568 381 0.053
multicellular organismal signaling GO:0035637 22 0.053
establishment of melanosome localization GO:0032401 19 0.051
regulation of rna metabolic process GO:0051252 224 0.050
cellular response to light stimulus GO:0071482 4 0.049
positive regulation of cellular process GO:0048522 201 0.049
embryonic skeletal system development GO:0048706 97 0.048
cilium assembly GO:0042384 58 0.048
regulation of cellular biosynthetic process GO:0031326 245 0.048
embryonic skeletal system morphogenesis GO:0048704 93 0.047
digestive tract morphogenesis GO:0048546 231 0.046
melanosome transport GO:0032402 19 0.046
lipid storage GO:0019915 1 0.045
developmental pigmentation GO:0048066 48 0.045
circulatory system process GO:0003013 87 0.045
embryonic hemopoiesis GO:0035162 53 0.044
nuclear migration GO:0007097 3 0.044
regulation of metal ion transport GO:0010959 4 0.043
spermatid development GO:0007286 2 0.043
cellular response to chemical stimulus GO:0070887 157 0.041
regulation of ion transmembrane transport GO:0034765 18 0.041
nucleobase containing compound biosynthetic process GO:0034654 205 0.041
inorganic ion transmembrane transport GO:0098660 57 0.041
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.040
sensory perception GO:0007600 39 0.039
sequestering of calcium ion GO:0051208 3 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.038
cell surface receptor signaling pathway GO:0007166 325 0.037
spermatid differentiation GO:0048515 2 0.037
ear development GO:0043583 127 0.037
aromatic compound biosynthetic process GO:0019438 217 0.036
establishment of localization in cell GO:0051649 77 0.036
skeletal system development GO:0001501 181 0.036
regulation of cell projection organization GO:0031344 44 0.035
regulation of jak stat cascade GO:0046425 3 0.035
multicellular organismal homeostasis GO:0048871 29 0.035
retinoic acid receptor signaling pathway GO:0048384 16 0.035
cellular component assembly GO:0022607 170 0.034
cellular component assembly involved in morphogenesis GO:0010927 107 0.034
heterocycle biosynthetic process GO:0018130 215 0.033
phototransduction visible light GO:0007603 2 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
gtp metabolic process GO:0046039 4 0.032
regulation of organelle assembly GO:1902115 4 0.032
adult behavior GO:0030534 2 0.032
tissue homeostasis GO:0001894 25 0.032
single organism organelle organization GO:1902589 199 0.032
aging GO:0007568 2 0.032
centrosome organization GO:0051297 1 0.032
negative regulation of response to stimulus GO:0048585 104 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
equilibrioception GO:0050957 2 0.031
inorganic cation transmembrane transport GO:0098662 50 0.031
transcription dna templated GO:0006351 181 0.031
nonmotile primary cilium assembly GO:0035058 2 0.031
regulation of sequestering of calcium ion GO:0051282 4 0.030
meiotic cell cycle process GO:1903046 3 0.030
rhodopsin mediated signaling pathway GO:0016056 1 0.030
ion transport GO:0006811 114 0.030
regulation of response to stimulus GO:0048583 269 0.030
melanosome localization GO:0032400 21 0.030
heart development GO:0007507 313 0.030
response to organic substance GO:0010033 153 0.030
hormone transport GO:0009914 2 0.029
biosynthetic process GO:0009058 294 0.029
chordate embryonic development GO:0043009 271 0.029
nerve development GO:0021675 45 0.029
fertilization GO:0009566 3 0.029
gene expression GO:0010467 252 0.028
positive regulation of transport GO:0051050 2 0.028
positive regulation of developmental process GO:0051094 50 0.028
apoptotic process GO:0006915 116 0.028
cellular response to lipopolysaccharide GO:0071222 3 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.027
sequestering of metal ion GO:0051238 3 0.027
organ formation GO:0048645 17 0.027
retina development in camera type eye GO:0060041 146 0.027
centrosome localization GO:0051642 1 0.027
regulation of dendrite morphogenesis GO:0048814 3 0.027
single organism membrane fusion GO:0044801 2 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
cellular component disassembly GO:0022411 1 0.026
neural retina development GO:0003407 49 0.026
l amino acid transport GO:0015807 1 0.026
regulation of gene expression GO:0010468 265 0.026
visual perception GO:0007601 17 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
regulation of localization GO:0032879 104 0.026
monovalent inorganic cation transport GO:0015672 42 0.026
sensory perception of mechanical stimulus GO:0050954 16 0.026
developmental maturation GO:0021700 34 0.026
regulation of locomotion GO:0040012 55 0.026
mechanoreceptor differentiation GO:0042490 37 0.025
negative regulation of behavior GO:0048521 6 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
negative regulation of macromolecule metabolic process GO:0010605 76 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
cation transport GO:0006812 81 0.025
anion transmembrane transport GO:0098656 12 0.024
cellular response to organic substance GO:0071310 105 0.024
microtubule organizing center organization GO:0031023 1 0.024
regulation of transmembrane transporter activity GO:0022898 2 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
positive regulation of synapse assembly GO:0051965 1 0.024
epithelial tube morphogenesis GO:0060562 148 0.024
regulation of response to cytokine stimulus GO:0060759 3 0.024
organelle fusion GO:0048284 3 0.024
stem cell division GO:0017145 1 0.024
heart morphogenesis GO:0003007 156 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
cellular macromolecule metabolic process GO:0044260 391 0.023
negative regulation of sequestering of calcium ion GO:0051283 4 0.023
regulation of biosynthetic process GO:0009889 250 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
regionalization GO:0003002 274 0.023
digestive tract development GO:0048565 265 0.022
mitotic cytokinesis GO:0000281 3 0.022
cell projection organization GO:0030030 284 0.022
intracellular transport GO:0046907 32 0.022
regulation of synapse assembly GO:0051963 3 0.022
regulation of dendrite development GO:0050773 3 0.022
synaptic vesicle endocytosis GO:0048488 1 0.022
rna biosynthetic process GO:0032774 181 0.022
innervation GO:0060384 3 0.022
larval development GO:0002164 2 0.022
tube closure GO:0060606 1 0.021
regulation of membrane repolarization GO:0060306 1 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
inner ear development GO:0048839 126 0.021
camera type eye development GO:0043010 222 0.021
morphogenesis of an epithelium GO:0002009 333 0.020
cortical cytoskeleton organization GO:0030865 1 0.020
cellular localization GO:0051641 97 0.020
meiotic nuclear division GO:0007126 4 0.020
cellular response to nutrient levels GO:0031669 2 0.020
detection of external stimulus GO:0009581 24 0.020
regulation of response to extracellular stimulus GO:0032104 1 0.020
regulation of circadian rhythm GO:0042752 4 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
negative regulation of synapse assembly GO:0051964 2 0.019
regulation of synapse organization GO:0050807 3 0.019
nephron epithelium morphogenesis GO:0072088 1 0.019
liver development GO:0001889 96 0.019
regulation of signaling GO:0023051 235 0.019
nuclear transport GO:0051169 4 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
regulation of binding GO:0051098 3 0.018
organic substance biosynthetic process GO:1901576 289 0.018
carboxylic acid transport GO:0046942 8 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
pigmentation GO:0043473 85 0.018
detection of visible light GO:0009584 12 0.018
regulation of membrane potential GO:0042391 23 0.018
myeloid cell differentiation GO:0030099 86 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
positive regulation of cell cycle GO:0045787 3 0.018
lipid metabolic process GO:0006629 52 0.017
phototransduction GO:0007602 2 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
cellular ketone metabolic process GO:0042180 11 0.017
anion transport GO:0006820 38 0.017
behavior GO:0007610 74 0.017
rna metabolic process GO:0016070 219 0.017
rna localization GO:0006403 4 0.017
regulation of neurotransmitter levels GO:0001505 5 0.017
sensory perception of light stimulus GO:0050953 19 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
retinal rod cell development GO:0046548 4 0.017
organelle assembly GO:0070925 110 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
cellular response to starvation GO:0009267 1 0.017
organic substance transport GO:0071702 58 0.017
negative regulation of metabolic process GO:0009892 86 0.016
establishment of pigment granule localization GO:0051905 22 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
camera type eye photoreceptor cell differentiation GO:0060219 19 0.016
small molecule catabolic process GO:0044282 3 0.016
blood circulation GO:0008015 87 0.016
immune system process GO:0002376 241 0.016
regulation of apoptotic process GO:0042981 98 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
organelle organization GO:0006996 227 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
sensory organ morphogenesis GO:0090596 200 0.016
actin filament based movement GO:0030048 1 0.016
detection of stimulus GO:0051606 29 0.016
nucleic acid templated transcription GO:0097659 181 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
somitogenesis GO:0001756 87 0.016
kupffer s vesicle development GO:0070121 50 0.016
calcium ion transmembrane transport GO:0070588 13 0.016
positive regulation of secretion GO:0051047 1 0.016
amine metabolic process GO:0009308 2 0.016
response to nutrient levels GO:0031667 10 0.016
multi organism process GO:0051704 134 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
regulation of neuron differentiation GO:0045664 56 0.015
single fertilization GO:0007338 3 0.015
synaptic vesicle recycling GO:0036465 1 0.015
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.015
anatomical structure homeostasis GO:0060249 36 0.015
cellular response to external stimulus GO:0071496 2 0.015
cortical actin cytoskeleton organization GO:0030866 1 0.015
absorption of visible light GO:0016038 2 0.015
skeletal system morphogenesis GO:0048705 102 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
hormone secretion GO:0046879 2 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
single organism behavior GO:0044708 24 0.015
polyol metabolic process GO:0019751 1 0.015
regulation of protein transport GO:0051223 3 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
inner ear receptor cell differentiation GO:0060113 29 0.015
cardiac conduction GO:0061337 3 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
regulation of wnt signaling pathway GO:0030111 53 0.015
protein metabolic process GO:0019538 183 0.015
response to glucose GO:0009749 3 0.015
mechanosensory behavior GO:0007638 2 0.015
regulation of gtpase activity GO:0043087 2 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.014
photoreceptor cell maintenance GO:0045494 11 0.014
tissue remodeling GO:0048771 4 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
positive regulation of jak stat cascade GO:0046427 2 0.014
central nervous system development GO:0007417 387 0.014
single organism membrane organization GO:0044802 20 0.014
cellular response to hormone stimulus GO:0032870 39 0.014
gamma aminobutyric acid signaling pathway GO:0007214 1 0.014
nucleus organization GO:0006997 7 0.014
mitochondrion organization GO:0007005 4 0.014
nitrogen compound transport GO:0071705 23 0.014
regulation of primary metabolic process GO:0080090 311 0.014
membrane fusion GO:0061025 2 0.014
nucleic acid metabolic process GO:0090304 244 0.014
digestive system development GO:0055123 289 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
gtp catabolic process GO:0006184 2 0.014
regulation of cell communication GO:0010646 232 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
response to hydrogen peroxide GO:0042542 3 0.014
embryonic heart tube development GO:0035050 133 0.014
heart contraction GO:0060047 71 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
regulation of growth rate GO:0040009 1 0.014
epithelial cell differentiation GO:0030855 116 0.013
antimicrobial humoral response GO:0019730 2 0.013
entrainment of circadian clock by photoperiod GO:0043153 1 0.013
regulation of cell activation GO:0050865 1 0.013
endomembrane system organization GO:0010256 13 0.013
membrane repolarization GO:0086009 2 0.013
regulation of cell differentiation GO:0045595 142 0.013
bmp signaling pathway GO:0030509 52 0.013
determination of bilateral symmetry GO:0009855 204 0.013
response to monosaccharide GO:0034284 3 0.013
transmission of nerve impulse GO:0019226 19 0.013
fat soluble vitamin metabolic process GO:0006775 4 0.013
nuclear envelope organization GO:0006998 2 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
endosomal transport GO:0016197 2 0.013
macroautophagy GO:0016236 1 0.013
regulation of cilium assembly GO:1902017 2 0.013
calcium ion import GO:0070509 4 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
fin development GO:0033333 77 0.013
developmental cell growth GO:0048588 52 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
protein import into nucleus GO:0006606 3 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
multicellular organismal response to stress GO:0033555 2 0.013
neuroblast proliferation GO:0007405 2 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
fluid transport GO:0042044 17 0.012
response to alkaloid GO:0043279 2 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
regulation of cytokine mediated signaling pathway GO:0001959 3 0.012
convergent extension involved in gastrulation GO:0060027 71 0.012
negative regulation of multi organism process GO:0043901 3 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
reproduction GO:0000003 40 0.012
vestibular reflex GO:0060005 2 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
heart looping GO:0001947 94 0.012
cell maturation GO:0048469 23 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
response to light intensity GO:0009642 1 0.012
regulation of cell shape GO:0008360 1 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
negative regulation of nervous system development GO:0051961 22 0.012
protein localization to plasma membrane GO:0072659 1 0.012
neurological system process GO:0050877 62 0.012
regulation of neuron projection development GO:0010975 40 0.012
divalent inorganic cation transport GO:0072511 21 0.012
camera type eye morphogenesis GO:0048593 108 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
cellular component biogenesis GO:0044085 178 0.012
hepaticobiliary system development GO:0061008 98 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
cellular biosynthetic process GO:0044249 286 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
organic acid metabolic process GO:0006082 31 0.012
regulation of calcium ion transport GO:0051924 2 0.012
response to vitamin GO:0033273 3 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
response to drug GO:0042493 3 0.011
protein secretion GO:0009306 1 0.011
cilium movement GO:0003341 26 0.011
response to external stimulus GO:0009605 264 0.011
regulation of transcription dna templated GO:0006355 213 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
response to food GO:0032094 1 0.011
neuron projection morphogenesis GO:0048812 161 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
hemopoiesis GO:0030097 183 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of microtubule based movement GO:0060632 3 0.011
cellular amine metabolic process GO:0044106 2 0.011
positive regulation of catabolic process GO:0009896 4 0.011
light induced release of internally sequestered calcium ion GO:0008377 1 0.011
metal ion transport GO:0030001 58 0.011
phagocytosis GO:0006909 3 0.011
organic acid transport GO:0015849 9 0.011
single organism metabolic process GO:0044710 217 0.011
response to chemical GO:0042221 320 0.011
small molecule metabolic process GO:0044281 77 0.011
autophagy GO:0006914 4 0.011
renal tubule morphogenesis GO:0061333 1 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of ph GO:0006885 3 0.011
regulation of nervous system development GO:0051960 90 0.011
response to ketone GO:1901654 1 0.011
response to hexose GO:0009746 3 0.011
osteoclast differentiation GO:0030316 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
dendrite development GO:0016358 9 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of cell motility GO:2000145 46 0.011
protein polymerization GO:0051258 4 0.011
cellular protein catabolic process GO:0044257 4 0.011
cellular protein complex disassembly GO:0043624 1 0.011
organonitrogen compound metabolic process GO:1901564 74 0.010
carbohydrate homeostasis GO:0033500 1 0.010
cellular component maintenance GO:0043954 3 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
homeostasis of number of cells within a tissue GO:0048873 4 0.010
inner ear receptor stereocilium organization GO:0060122 8 0.010
protein targeting to nucleus GO:0044744 3 0.010
macromolecular complex disassembly GO:0032984 1 0.010
synaptic target recognition GO:0008039 1 0.010
primary neural tube formation GO:0014020 1 0.010

pdzd7a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
nervous system disease DOID:863 0 0.047
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
auditory system disease DOID:2742 0 0.015
nonsyndromic deafness DOID:0050563 0 0.015