Danio rerio

33 known processes

LOC100000685

similar to OCTN2 protein

(Aliases: slc22a5)

LOC100000685 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 274 0.077
larval development GO:0002164 2 0.065
signal transduction GO:0007165 455 0.064
embryonic organ development GO:0048568 381 0.062
digestive system development GO:0055123 289 0.061
chordate embryonic development GO:0043009 271 0.056
regulation of signal transduction GO:0009966 225 0.053
anterior posterior pattern specification GO:0009952 152 0.046
heart development GO:0007507 313 0.045
regionalization GO:0003002 274 0.045
tube morphogenesis GO:0035239 349 0.043
regulation of signaling GO:0023051 235 0.043
cell surface receptor signaling pathway GO:0007166 325 0.043
regulation of multicellular organism growth GO:0040014 4 0.040
response to chemical GO:0042221 320 0.039
regulation of response to stimulus GO:0048583 269 0.039
brain development GO:0007420 293 0.038
regulation of cell communication GO:0010646 232 0.038
morphogenesis of an epithelium GO:0002009 333 0.037
gastrulation GO:0007369 208 0.037
sensory organ morphogenesis GO:0090596 200 0.034
aging GO:0007568 2 0.034
regulation of gene expression GO:0010468 265 0.032
sensory organ development GO:0007423 393 0.032
head development GO:0060322 303 0.031
meiotic nuclear division GO:0007126 4 0.030
stem cell maintenance GO:0019827 4 0.030
cognition GO:0050890 1 0.030
central nervous system development GO:0007417 387 0.030
lipid storage GO:0019915 1 0.028
vasculature development GO:0001944 278 0.028
muscle structure development GO:0061061 196 0.028
cellular macromolecule metabolic process GO:0044260 391 0.028
maintenance of location GO:0051235 4 0.027
positive regulation of transport GO:0051050 2 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
cellular component movement GO:0006928 335 0.027
multicellular organism growth GO:0035264 4 0.027
locomotion GO:0040011 313 0.027
cellular nitrogen compound metabolic process GO:0034641 290 0.026
embryonic skeletal system development GO:0048706 97 0.026
protein localization to nucleus GO:0034504 3 0.026
cellular component morphogenesis GO:0032989 336 0.026
phagocytosis GO:0006909 3 0.026
positive regulation of catabolic process GO:0009896 4 0.026
cell migration GO:0016477 237 0.025
neural crest cell differentiation GO:0014033 72 0.024
golgi vesicle transport GO:0048193 3 0.024
regulation of synapse organization GO:0050807 3 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
generation of neurons GO:0048699 385 0.024
cell part morphogenesis GO:0032990 246 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
adult behavior GO:0030534 2 0.023
regulation of biological quality GO:0065008 263 0.023
single organism metabolic process GO:0044710 217 0.023
heart morphogenesis GO:0003007 156 0.023
skeletal system development GO:0001501 181 0.023
cell morphogenesis GO:0000902 289 0.023
biosynthetic process GO:0009058 294 0.023
regulation of metabolic process GO:0019222 359 0.023
digestive tract morphogenesis GO:0048546 231 0.023
organic cyclic compound metabolic process GO:1901360 301 0.022
sleep GO:0030431 1 0.022
regulation of synaptic plasticity GO:0048167 1 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
ameboidal type cell migration GO:0001667 143 0.022
regulation of cytokine production GO:0001817 3 0.022
regulation of metal ion transport GO:0010959 4 0.022
gene expression GO:0010467 252 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
localization of cell GO:0051674 244 0.021
meiotic cell cycle process GO:1903046 3 0.021
positive regulation of biological process GO:0048518 253 0.021
response to drug GO:0042493 3 0.021
single organism transport GO:0044765 206 0.021
camera type eye development GO:0043010 222 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
rna biosynthetic process GO:0032774 181 0.020
single organism organelle organization GO:1902589 199 0.020
neuron projection morphogenesis GO:0048812 161 0.020
convergent extension involved in gastrulation GO:0060027 71 0.020
heart looping GO:0001947 94 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
regulation of primary metabolic process GO:0080090 311 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
positive regulation of cytokine production GO:0001819 2 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
endocrine process GO:0050886 2 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
hormone transport GO:0009914 2 0.019
heterocycle metabolic process GO:0046483 290 0.019
nucleic acid templated transcription GO:0097659 181 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
blood vessel development GO:0001568 246 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
response to alkaloid GO:0043279 2 0.019
eye morphogenesis GO:0048592 144 0.019
digestive tract development GO:0048565 265 0.019
determination of bilateral symmetry GO:0009855 204 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
eye development GO:0001654 277 0.019
regulation of protein transport GO:0051223 3 0.018
negative regulation of biological process GO:0048519 304 0.018
organic substance biosynthetic process GO:1901576 289 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
lateral inhibition GO:0046331 1 0.018
mitochondrion organization GO:0007005 4 0.018
meiotic chromosome segregation GO:0045132 3 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
olfactory lobe development GO:0021988 4 0.018
regulation of synapse assembly GO:0051963 3 0.018
cellular amine metabolic process GO:0044106 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of biosynthetic process GO:0009889 250 0.018
protein import GO:0017038 3 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
taxis GO:0042330 109 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
single fertilization GO:0007338 3 0.017
cell motility GO:0048870 244 0.017
rna metabolic process GO:0016070 219 0.017
organic acid metabolic process GO:0006082 31 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
ear development GO:0043583 127 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
skeletal system morphogenesis GO:0048705 102 0.017
cell projection morphogenesis GO:0048858 244 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
retina development in camera type eye GO:0060041 146 0.017
specification of symmetry GO:0009799 204 0.017
response to stress GO:0006950 263 0.017
amine metabolic process GO:0009308 2 0.017
regulation of protein catabolic process GO:0042176 1 0.017
mesenchyme development GO:0060485 127 0.017
neuron differentiation GO:0030182 353 0.017
neurotransmitter transport GO:0006836 2 0.017
regulation of transcription dna templated GO:0006355 213 0.017
nuclear import GO:0051170 3 0.017
response to organic substance GO:0010033 153 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.016
protein targeting to nucleus GO:0044744 3 0.016
organic acid catabolic process GO:0016054 3 0.016
skeletal muscle tissue development GO:0007519 67 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
somatic muscle development GO:0007525 4 0.016
negative regulation of cellular process GO:0048523 283 0.016
nucleic acid metabolic process GO:0090304 244 0.016
cellular biosynthetic process GO:0044249 286 0.016
system process GO:0003008 185 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
cellular protein catabolic process GO:0044257 4 0.016
response to uv GO:0009411 3 0.016
regulation of transporter activity GO:0032409 2 0.016
neuron development GO:0048666 262 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
forebrain development GO:0030900 96 0.016
cellular ketone metabolic process GO:0042180 11 0.016
nuclear transport GO:0051169 4 0.016
epithelial cell differentiation GO:0030855 116 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
cellular response to external stimulus GO:0071496 2 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
regulation of rna metabolic process GO:0051252 224 0.016
rna localization GO:0006403 4 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
positive regulation of immune effector process GO:0002699 3 0.015
axon development GO:0061564 166 0.015
endosomal transport GO:0016197 2 0.015
single organism nuclear import GO:1902593 3 0.015
cell fate specification GO:0001708 68 0.015
hormone secretion GO:0046879 2 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
urogenital system development GO:0001655 97 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
lipid catabolic process GO:0016042 4 0.015
somitogenesis GO:0001756 87 0.015
regulation of protein complex assembly GO:0043254 3 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
embryonic heart tube development GO:0035050 133 0.015
phagocytosis engulfment GO:0006911 1 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
response to hexose GO:0009746 3 0.015
gtp catabolic process GO:0006184 2 0.015
embryonic cranial skeleton morphogenesis GO:0048701 90 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
protein homooligomerization GO:0051260 3 0.015
protein metabolic process GO:0019538 183 0.015
regulation of cell death GO:0010941 103 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of cell activation GO:0050865 1 0.015
small molecule metabolic process GO:0044281 77 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
cell cycle g2 m phase transition GO:0044839 4 0.014
positive regulation of cellular process GO:0048522 201 0.014
gland development GO:0048732 143 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
atp catabolic process GO:0006200 4 0.014
regulation of tube size GO:0035150 2 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
regulation of blood vessel size GO:0050880 2 0.014
cellular component disassembly GO:0022411 1 0.014
determination of left right symmetry GO:0007368 179 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.014
carbohydrate homeostasis GO:0033500 1 0.014
negative regulation of defense response GO:0031348 2 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
single organism localization GO:1902578 225 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
mononuclear cell proliferation GO:0032943 1 0.014
synaptic vesicle localization GO:0097479 1 0.014
regulation of hormone secretion GO:0046883 2 0.014
protein import into nucleus GO:0006606 3 0.014
membrane invagination GO:0010324 1 0.014
wnt signaling pathway GO:0016055 80 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
compound eye development GO:0048749 2 0.014
peptide transport GO:0015833 1 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
convergent extension GO:0060026 118 0.014
positive regulation of chromatin modification GO:1903310 1 0.013
stem cell proliferation GO:0072089 4 0.013
ion transmembrane transport GO:0034220 91 0.013
amino acid transport GO:0006865 2 0.013
small molecule catabolic process GO:0044282 3 0.013
cell projection organization GO:0030030 284 0.013
cellular response to light stimulus GO:0071482 4 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
neural crest cell development GO:0014032 62 0.013
regulation of apoptotic process GO:0042981 98 0.013
protein dephosphorylation GO:0006470 3 0.013
cartilage development GO:0051216 96 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
response to amine GO:0014075 1 0.013
protein acylation GO:0043543 3 0.013
transport GO:0006810 220 0.013
response to carbohydrate GO:0009743 3 0.013
death GO:0016265 121 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
protein complex disassembly GO:0043241 1 0.013
stem cell differentiation GO:0048863 117 0.013
hemopoiesis GO:0030097 183 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
positive regulation of blood circulation GO:1903524 2 0.013
sensory perception of smell GO:0007608 2 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
establishment of localization GO:0051234 244 0.013
regulation of lymphangiogenesis GO:1901490 4 0.013
regulation of dendrite development GO:0050773 3 0.013
transmembrane transport GO:0055085 120 0.013
protein stabilization GO:0050821 2 0.013
muscle cell development GO:0055001 115 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
axonogenesis GO:0007409 152 0.013
camera type eye morphogenesis GO:0048593 108 0.013
leukocyte mediated cytotoxicity GO:0001909 1 0.013
neuron projection development GO:0031175 180 0.013
organelle organization GO:0006996 227 0.013
cellular response to starvation GO:0009267 1 0.013
centrosome organization GO:0051297 1 0.013
lens fiber cell morphogenesis GO:0070309 3 0.013
protein acetylation GO:0006473 2 0.013
programmed cell death GO:0012501 119 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
b cell activation GO:0042113 2 0.013
positive regulation of histone modification GO:0031058 1 0.013
homeostatic process GO:0042592 142 0.013
fertilization GO:0009566 3 0.013
regulation of reproductive process GO:2000241 4 0.012
chemotaxis GO:0006935 104 0.012
response to monosaccharide GO:0034284 3 0.012
sequestering of metal ion GO:0051238 3 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
cell death GO:0008219 121 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
apoptotic process GO:0006915 116 0.012
multi organism process GO:0051704 134 0.012
oxoacid metabolic process GO:0043436 31 0.012
regulation of endothelial cell proliferation GO:0001936 1 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
bmp signaling pathway GO:0030509 52 0.012
multi organism cellular process GO:0044764 2 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
regulation of sodium ion transport GO:0002028 2 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
response to abiotic stimulus GO:0009628 122 0.012
regulation of protein polymerization GO:0032271 2 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
regulation of circadian rhythm GO:0042752 4 0.012
blood vessel morphogenesis GO:0048514 216 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
er to golgi vesicle mediated transport GO:0006888 1 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
antimicrobial humoral response GO:0019730 2 0.012
transcription dna templated GO:0006351 181 0.012
cellular amide metabolic process GO:0043603 4 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
regulation of cell projection assembly GO:0060491 4 0.012
positive regulation of secretion GO:0051047 1 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
intracellular signal transduction GO:0035556 85 0.012
cellular response to nutrient levels GO:0031669 2 0.012
cellular component biogenesis GO:0044085 178 0.012
protein polymerization GO:0051258 4 0.012
cellular component assembly GO:0022607 170 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
interspecies interaction between organisms GO:0044419 4 0.012
regulation of dna replication GO:0006275 3 0.012
response to superoxide GO:0000303 2 0.012
inner ear development GO:0048839 126 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
chemosensory behavior GO:0007635 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
skeletal muscle organ development GO:0060538 78 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
regulation of oocyte development GO:0060281 3 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
b cell differentiation GO:0030183 1 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
positive regulation of cell activation GO:0050867 1 0.011
post embryonic organ development GO:0048569 4 0.011
lymph vessel development GO:0001945 27 0.011
neurotransmitter secretion GO:0007269 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
negative regulation of cell communication GO:0010648 96 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
cytoplasm organization GO:0007028 4 0.011
intracellular mrna localization GO:0008298 1 0.011
organism emergence from protective structure GO:0071684 4 0.011
appendage development GO:0048736 80 0.011
response to glucose GO:0009749 3 0.011
lymphocyte proliferation GO:0046651 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
gtp metabolic process GO:0046039 4 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
leukocyte proliferation GO:0070661 1 0.011
synaptic target recognition GO:0008039 1 0.011
cytokinesis GO:0000910 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
response to external stimulus GO:0009605 264 0.011
muscle tissue development GO:0060537 110 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
endocrine hormone secretion GO:0060986 2 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of reproductive process GO:2000243 2 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
renal system development GO:0072001 94 0.011
positive regulation of cell cycle GO:0045787 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
positive regulation of cell killing GO:0031343 2 0.011
muscle fiber development GO:0048747 52 0.011
muscle cell differentiation GO:0042692 139 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
protein localization to plasma membrane GO:0072659 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
positive regulation of glucose transport GO:0010828 1 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
somite development GO:0061053 96 0.010
growth GO:0040007 174 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
oocyte anterior posterior axis specification GO:0007314 4 0.010
cellular protein metabolic process GO:0044267 129 0.010
regulation of programmed cell death GO:0043067 101 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
regulation of developmental process GO:0050793 247 0.010
positive regulation of metabolic process GO:0009893 108 0.010
appendage morphogenesis GO:0035107 56 0.010
lens fiber cell development GO:0070307 3 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
regulation of calcium ion transport GO:0051924 2 0.010
axon guidance GO:0007411 86 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
cell killing GO:0001906 2 0.010
pronuclear migration GO:0035046 1 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
regulation of blood pressure GO:0008217 1 0.010
synaptic vesicle transport GO:0048489 1 0.010
sequestering of calcium ion GO:0051208 3 0.010
dicarboxylic acid transport GO:0006835 1 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
neuroblast proliferation GO:0007405 2 0.010
locomotor rhythm GO:0045475 3 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
regulation of lipid transport GO:0032368 4 0.010
angiogenesis GO:0001525 158 0.010
striated muscle tissue development GO:0014706 110 0.010
regulation of protein targeting GO:1903533 2 0.010
calcium ion transport into cytosol GO:0060402 3 0.010

LOC100000685 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012