Danio rerio

0 known processes

tmprss4b

transmembrane protease, serine 4b

(Aliases: wu:fi21e09,fi21e09,si:ch211-139a5.6)

tmprss4b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression GO:0010468 265 0.340
gene expression GO:0010467 252 0.227
regulation of transcription dna templated GO:0006355 213 0.203
regulation of metabolic process GO:0019222 359 0.179
nucleic acid metabolic process GO:0090304 244 0.155
negative regulation of biological process GO:0048519 304 0.155
heterocycle biosynthetic process GO:0018130 215 0.140
cellular nitrogen compound metabolic process GO:0034641 290 0.133
cellular macromolecule biosynthetic process GO:0034645 224 0.124
organic cyclic compound metabolic process GO:1901360 301 0.123
cellular biosynthetic process GO:0044249 286 0.123
meiotic nuclear division GO:0007126 4 0.119
rna biosynthetic process GO:0032774 181 0.114
biosynthetic process GO:0009058 294 0.113
regulation of macromolecule metabolic process GO:0060255 317 0.111
rna metabolic process GO:0016070 219 0.111
cellular macromolecule metabolic process GO:0044260 391 0.106
nitrogen compound metabolic process GO:0006807 319 0.097
nucleobase containing compound biosynthetic process GO:0034654 205 0.094
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.093
cellular amine metabolic process GO:0044106 2 0.085
sensory organ development GO:0007423 393 0.084
optomotor response GO:0071632 1 0.080
regulation of primary metabolic process GO:0080090 311 0.079
regulation of macromolecule biosynthetic process GO:0010556 225 0.077
negative regulation of gene expression GO:0010629 65 0.073
heterocycle metabolic process GO:0046483 290 0.069
cell fate commitment GO:0045165 99 0.069
negative regulation of cellular process GO:0048523 283 0.067
regulation of rna metabolic process GO:0051252 224 0.066
regulation of biological quality GO:0065008 263 0.065
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.065
mitotic cell cycle process GO:1903047 48 0.062
aromatic compound biosynthetic process GO:0019438 217 0.062
regulation of metal ion transport GO:0010959 4 0.062
chordate embryonic development GO:0043009 271 0.061
cellular aromatic compound metabolic process GO:0006725 295 0.060
response to external stimulus GO:0009605 264 0.060
retina development in camera type eye GO:0060041 146 0.059
cation transport GO:0006812 81 0.059
immunoglobulin mediated immune response GO:0016064 3 0.058
transcription dna templated GO:0006351 181 0.057
regulation of cellular biosynthetic process GO:0031326 245 0.057
positive regulation of transport GO:0051050 2 0.056
regulation of biosynthetic process GO:0009889 250 0.055
negative regulation of cellular metabolic process GO:0031324 77 0.055
regulation of rna biosynthetic process GO:2001141 213 0.055
nucleic acid templated transcription GO:0097659 181 0.053
regulation of cellular metabolic process GO:0031323 320 0.052
meiotic cell cycle process GO:1903046 3 0.050
larval development GO:0002164 2 0.050
morphogenesis of an epithelium GO:0002009 333 0.049
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.049
retina morphogenesis in camera type eye GO:0060042 79 0.048
regulation of multicellular organismal process GO:0051239 277 0.047
head development GO:0060322 303 0.045
organic cyclic compound biosynthetic process GO:1901362 223 0.045
positive regulation of immune effector process GO:0002699 3 0.043
single organism localization GO:1902578 225 0.042
epidermal cell fate specification GO:0009957 4 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.042
brain development GO:0007420 293 0.042
response to chemical GO:0042221 320 0.042
regulation of nucleic acid templated transcription GO:1903506 213 0.042
macromolecule biosynthetic process GO:0009059 227 0.042
regulation of cell activation GO:0050865 1 0.042
eye morphogenesis GO:0048592 144 0.041
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
regulation of leukocyte mediated immunity GO:0002703 1 0.040
central nervous system development GO:0007417 387 0.040
leukocyte proliferation GO:0070661 1 0.039
tube morphogenesis GO:0035239 349 0.039
regulation of nitrogen compound metabolic process GO:0051171 251 0.038
ovulation cycle process GO:0022602 2 0.038
negative regulation of metabolic process GO:0009892 86 0.038
epithelial tube morphogenesis GO:0060562 148 0.037
organelle organization GO:0006996 227 0.037
organic substance biosynthetic process GO:1901576 289 0.037
cell death GO:0008219 121 0.037
neuron differentiation GO:0030182 353 0.037
regulation of programmed cell death GO:0043067 101 0.037
inorganic cation transmembrane transport GO:0098662 50 0.037
positive regulation of biological process GO:0048518 253 0.037
aging GO:0007568 2 0.036
single organism metabolic process GO:0044710 217 0.035
ion transport GO:0006811 114 0.035
mitochondrion organization GO:0007005 4 0.034
embryo development ending in birth or egg hatching GO:0009792 271 0.034
cell fate specification GO:0001708 68 0.034
eye development GO:0001654 277 0.034
transmembrane transport GO:0055085 120 0.033
oocyte maturation GO:0001556 4 0.033
heart looping GO:0001947 94 0.033
apoptotic process GO:0006915 116 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.032
mitotic cell cycle GO:0000278 64 0.031
negative regulation of macromolecule metabolic process GO:0010605 76 0.031
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 1 0.031
cellular response to chemical stimulus GO:0070887 157 0.030
mononuclear cell proliferation GO:0032943 1 0.029
spermatid development GO:0007286 2 0.029
stem cell proliferation GO:0072089 4 0.029
regulation of circadian rhythm GO:0042752 4 0.028
stem cell division GO:0017145 1 0.028
cell projection organization GO:0030030 284 0.028
blood vessel development GO:0001568 246 0.028
regulation of developmental process GO:0050793 247 0.028
cellular response to nutrient levels GO:0031669 2 0.028
signal transduction GO:0007165 455 0.027
programmed cell death GO:0012501 119 0.027
homeostatic process GO:0042592 142 0.027
determination of heart left right asymmetry GO:0061371 117 0.027
regulation of autophagy GO:0010506 3 0.027
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.027
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.026
regulation of immune system process GO:0002682 34 0.026
neuroblast proliferation GO:0007405 2 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.026
skeletal system development GO:0001501 181 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.025
camera type eye development GO:0043010 222 0.025
b cell mediated immunity GO:0019724 3 0.025
establishment of localization GO:0051234 244 0.025
female gonad development GO:0008585 4 0.025
lateral line system development GO:0048925 76 0.025
epithelial cell differentiation GO:0030855 116 0.025
death GO:0016265 121 0.025
positive regulation of cell cycle GO:0045787 3 0.024
cellular response to external stimulus GO:0071496 2 0.024
dorsal ventral pattern formation GO:0009953 125 0.023
system process GO:0003008 185 0.023
mesenchymal cell differentiation GO:0048762 87 0.023
regulation of apoptotic process GO:0042981 98 0.023
lipid storage GO:0019915 1 0.023
neuron development GO:0048666 262 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
golgi vesicle transport GO:0048193 3 0.023
negative regulation of mitosis GO:0045839 3 0.023
circulatory system process GO:0003013 87 0.023
epidermis development GO:0008544 48 0.023
positive regulation of lipid metabolic process GO:0045834 1 0.023
meiotic chromosome segregation GO:0045132 3 0.022
calcium ion import GO:0070509 4 0.022
regulation of reproductive process GO:2000241 4 0.022
response to abiotic stimulus GO:0009628 122 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
cell cycle GO:0007049 93 0.022
male meiosis GO:0007140 2 0.022
translational initiation GO:0006413 3 0.022
metal ion transport GO:0030001 58 0.021
sodium ion transport GO:0006814 24 0.021
amine metabolic process GO:0009308 2 0.021
response to stress GO:0006950 263 0.021
astrocyte differentiation GO:0048708 1 0.021
negative regulation of biosynthetic process GO:0009890 55 0.021
camera type eye morphogenesis GO:0048593 108 0.021
regulation of mitotic cell cycle GO:0007346 25 0.021
embryonic organ morphogenesis GO:0048562 274 0.020
regulation of immunoglobulin production GO:0002637 1 0.020
regulation of sodium ion transport GO:0002028 2 0.020
regulation of ph GO:0006885 3 0.020
generation of neurons GO:0048699 385 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
organelle fission GO:0048285 23 0.020
immune system process GO:0002376 241 0.019
positive regulation of cell activation GO:0050867 1 0.019
cellular amide metabolic process GO:0043603 4 0.019
response to nutrient GO:0007584 3 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
regulation of cellular protein metabolic process GO:0032268 52 0.019
positive regulation of inflammatory response GO:0050729 1 0.019
positive regulation of translation GO:0045727 1 0.019
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.018
embryonic heart tube development GO:0035050 133 0.018
positive regulation of catabolic process GO:0009896 4 0.018
muscle organ development GO:0007517 101 0.018
transport GO:0006810 220 0.018
detection of chemical stimulus GO:0009593 4 0.018
protein metabolic process GO:0019538 183 0.017
fin morphogenesis GO:0033334 53 0.017
apoptotic process involved in morphogenesis GO:0060561 2 0.017
lymphocyte proliferation GO:0046651 1 0.017
regulation of calcium ion transport GO:0051924 2 0.017
response to glucocorticoid GO:0051384 1 0.017
negative regulation of rna metabolic process GO:0051253 48 0.017
striated muscle tissue development GO:0014706 110 0.017
cellular protein metabolic process GO:0044267 129 0.017
regulation of signaling GO:0023051 235 0.017
appendage development GO:0048736 80 0.017
regulation of binding GO:0051098 3 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
response to antibiotic GO:0046677 1 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
regulation of cytokine production GO:0001817 3 0.016
regionalization GO:0003002 274 0.016
ovarian follicle development GO:0001541 2 0.016
female sex differentiation GO:0046660 4 0.016
development of primary female sexual characteristics GO:0046545 4 0.015
spemann organizer formation at the embryonic shield GO:0060063 2 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
vasculature development GO:0001944 278 0.015
positive regulation of secretion GO:0051047 1 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
regulation of cell communication GO:0010646 232 0.015
regulation of embryonic development GO:0045995 47 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
maintenance of location GO:0051235 4 0.015
sodium ion transmembrane transport GO:0035725 21 0.015
locomotion GO:0040011 313 0.015
muscle structure development GO:0061061 196 0.015
negative regulation of apoptotic process GO:0043066 55 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
ion transmembrane transport GO:0034220 91 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
heart development GO:0007507 313 0.014
single organism transport GO:0044765 206 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.013
digestive system development GO:0055123 289 0.013
mesoderm development GO:0007498 88 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.013
cell killing GO:0001906 2 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
cytokinesis GO:0000910 3 0.013
appendage morphogenesis GO:0035107 56 0.013
blood circulation GO:0008015 87 0.013
cellular ketone metabolic process GO:0042180 11 0.013
cellular response to oxygen levels GO:0071453 1 0.013
anion transport GO:0006820 38 0.013
phagocytosis GO:0006909 3 0.013
cellular response to starvation GO:0009267 1 0.012
determination of ventral identity GO:0048264 21 0.012
anatomical structure homeostasis GO:0060249 36 0.012
connective tissue development GO:0061448 99 0.012
lipid metabolic process GO:0006629 52 0.012
nuclear division GO:0000280 23 0.012
regulation of cell death GO:0010941 103 0.012
developmental growth GO:0048589 166 0.012
cellular protein catabolic process GO:0044257 4 0.012
positive regulation of multi organism process GO:0043902 3 0.012
positive regulation of metabolic process GO:0009893 108 0.012
regulation of blood pressure GO:0008217 1 0.012
oxidation reduction process GO:0055114 41 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
striated muscle cell differentiation GO:0051146 129 0.012
regulation of inflammatory response GO:0050727 2 0.012
skin development GO:0043588 54 0.012
multicellular organism growth GO:0035264 4 0.012
autophagy GO:0006914 4 0.012
negative regulation of catalytic activity GO:0043086 21 0.012
embryonic organ development GO:0048568 381 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
positive regulation of rna biosynthetic process GO:1902680 57 0.012
positive regulation of carbohydrate metabolic process GO:0045913 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
determination of bilateral symmetry GO:0009855 204 0.012
mitotic cell cycle embryonic GO:0045448 2 0.012
macromolecule deacylation GO:0098732 3 0.012
oxoacid metabolic process GO:0043436 31 0.012
sensory organ morphogenesis GO:0090596 200 0.012
stem cell maintenance GO:0019827 4 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
regulation of establishment of protein localization GO:0070201 4 0.011
phosphatidylinositol biosynthetic process GO:0006661 1 0.011
nerve development GO:0021675 45 0.011
response to corticosteroid GO:0031960 1 0.011
lymphocyte mediated immunity GO:0002449 5 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
organic acid metabolic process GO:0006082 31 0.011
regulation of molecular function GO:0065009 70 0.011
macromolecule modification GO:0043412 111 0.011
response to organic cyclic compound GO:0014070 51 0.011
regulation of immune effector process GO:0002697 5 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
positive regulation of cytokine production GO:0001819 2 0.011
negative regulation of kinase activity GO:0033673 4 0.011
formation of primary germ layer GO:0001704 62 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
negative regulation of ras protein signal transduction GO:0046580 1 0.011
negative regulation of cell fate specification GO:0009996 11 0.011
negative regulation of multi organism process GO:0043901 3 0.011
small molecule metabolic process GO:0044281 77 0.011
muscle cell differentiation GO:0042692 139 0.011
regulation of dna replication GO:0006275 3 0.011
epidermal cell differentiation GO:0009913 36 0.011
chemical homeostasis GO:0048878 49 0.011
negative regulation of molecular function GO:0044092 23 0.011
sleep GO:0030431 1 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
neuron cellular homeostasis GO:0070050 3 0.010
b cell activation GO:0042113 2 0.010
regulation of cell cycle GO:0051726 52 0.010
bone remodeling GO:0046849 2 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
positive regulation of defense response GO:0031349 9 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
response to nitrogen compound GO:1901698 19 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
peptide transport GO:0015833 1 0.010

tmprss4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
nervous system disease DOID:863 0 0.012
eye disease DOID:5614 0 0.012