Danio rerio

33 known processes

c1qc

complement component 1, q subcomponent, C chain

(Aliases: zgc:103597)

c1qc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
activation of immune response GO:0002253 9 0.685
defense response to other organism GO:0098542 33 0.325
vasculature development GO:0001944 278 0.296
signal transduction GO:0007165 455 0.287
blood vessel morphogenesis GO:0048514 216 0.286
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.231
defense response GO:0006952 47 0.177
leukocyte proliferation GO:0070661 1 0.172
immune system process GO:0002376 241 0.170
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.160
positive regulation of cytokine production GO:0001819 2 0.156
response to stress GO:0006950 263 0.136
positive regulation of biological process GO:0048518 253 0.127
regulation of primary metabolic process GO:0080090 311 0.127
blood vessel development GO:0001568 246 0.117
angiogenesis GO:0001525 158 0.115
adaptive immune response GO:0002250 5 0.115
regulation of cytokine production GO:0001817 3 0.114
immune response GO:0006955 28 0.113
mononuclear cell proliferation GO:0032943 1 0.103
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.102
protein activation cascade GO:0072376 6 0.102
positive regulation of immune system process GO:0002684 17 0.093
positive regulation of stress activated mapk cascade GO:0032874 3 0.087
response to organic substance GO:0010033 153 0.082
immunoglobulin mediated immune response GO:0016064 3 0.081
regulation of production of molecular mediator of immune response GO:0002700 1 0.076
sprouting angiogenesis GO:0002040 53 0.073
regulation of immune system process GO:0002682 34 0.073
regulation of response to cytokine stimulus GO:0060759 3 0.070
regulation of stem cell proliferation GO:0072091 2 0.068
regulation of cellular amino acid metabolic process GO:0006521 0 0.067
regulation of macromolecule metabolic process GO:0060255 317 0.062
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.061
regulation of multicellular organismal process GO:0051239 277 0.060
lymphocyte mediated immunity GO:0002449 5 0.057
positive regulation of cellular process GO:0048522 201 0.057
i kappab kinase nf kappab signaling GO:0007249 4 0.055
cellular amino acid metabolic process GO:0006520 7 0.054
positive regulation of immune response GO:0050778 11 0.053
positive regulation of response to stimulus GO:0048584 80 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.051
cellular protein catabolic process GO:0044257 4 0.051
innate immune response GO:0045087 13 0.049
immune effector process GO:0002252 23 0.049
regulation of protein transport GO:0051223 3 0.049
positive regulation of immune effector process GO:0002699 3 0.048
cellular amine metabolic process GO:0044106 2 0.048
b cell mediated immunity GO:0019724 3 0.047
positive regulation of map kinase activity GO:0043406 3 0.047
b cell activation GO:0042113 2 0.047
response to external biotic stimulus GO:0043207 97 0.046
positive regulation of cell activation GO:0050867 1 0.045
stem cell proliferation GO:0072089 4 0.043
developmental growth GO:0048589 166 0.042
response to other organism GO:0051707 97 0.042
regulation of developmental process GO:0050793 247 0.041
organic acid metabolic process GO:0006082 31 0.041
positive regulation of leukocyte mediated immunity GO:0002705 1 0.041
synaptic growth at neuromuscular junction GO:0051124 2 0.039
positive regulation of wound healing GO:0090303 1 0.039
positive regulation of stem cell proliferation GO:2000648 1 0.038
positive regulation of transport GO:0051050 2 0.037
oxoacid metabolic process GO:0043436 31 0.037
amine metabolic process GO:0009308 2 0.037
cellular ketone metabolic process GO:0042180 11 0.037
cellular macromolecule metabolic process GO:0044260 391 0.037
regulation of cell activation GO:0050865 1 0.036
response to wounding GO:0009611 116 0.036
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.036
type i interferon production GO:0032606 2 0.036
complement activation GO:0006956 3 0.036
lymphocyte proliferation GO:0046651 1 0.036
response to abiotic stimulus GO:0009628 122 0.035
positive regulation of cellular component biogenesis GO:0044089 3 0.035
response to biotic stimulus GO:0009607 97 0.035
production of molecular mediator of immune response GO:0002440 2 0.034
cellular protein metabolic process GO:0044267 129 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.033
negative regulation of response to cytokine stimulus GO:0060761 2 0.033
immunoglobulin production GO:0002377 1 0.033
regulation of inflammatory response GO:0050727 2 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.033
regulation of multicellular organismal development GO:2000026 223 0.033
regulation of immune response GO:0050776 14 0.032
interferon beta production GO:0032608 1 0.032
lateral line development GO:0048882 66 0.032
response to external stimulus GO:0009605 264 0.031
toll like receptor signaling pathway GO:0002224 4 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
collagen metabolic process GO:0032963 2 0.031
response to bacterium GO:0009617 58 0.031
apoptotic process involved in development GO:1902742 2 0.031
interspecies interaction between organisms GO:0044419 4 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.030
superoxide metabolic process GO:0006801 2 0.030
positive regulation of innate immune response GO:0045089 8 0.030
positive regulation of dna metabolic process GO:0051054 1 0.030
sensory system development GO:0048880 76 0.030
regulation of response to stimulus GO:0048583 269 0.029
aging GO:0007568 2 0.029
muscle cell development GO:0055001 115 0.029
regulation of programmed cell death GO:0043067 101 0.028
positive regulation of jnk cascade GO:0046330 3 0.028
multicellular organismal metabolic process GO:0044236 2 0.028
internal protein amino acid acetylation GO:0006475 2 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
peptidyl lysine acetylation GO:0018394 2 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
negative regulation of cytokine production GO:0001818 1 0.027
protein acetylation GO:0006473 2 0.027
single organism metabolic process GO:0044710 217 0.027
positive regulation of secretion by cell GO:1903532 1 0.027
regulation of leukocyte mediated immunity GO:0002703 1 0.027
regulation of cytokine biosynthetic process GO:0042035 1 0.026
modification dependent protein catabolic process GO:0019941 3 0.026
regulation of metabolic process GO:0019222 359 0.026
death GO:0016265 121 0.026
positive regulation of cell killing GO:0031343 2 0.026
nuclear transport GO:0051169 4 0.026
protein metabolic process GO:0019538 183 0.026
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.025
phosphatidylinositol mediated signaling GO:0048015 2 0.025
phagocytosis GO:0006909 3 0.025
regulation of multicellular organism growth GO:0040014 4 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
response to glucocorticoid GO:0051384 1 0.024
cellular response to chemical stimulus GO:0070887 157 0.024
internal peptidyl lysine acetylation GO:0018393 2 0.024
regulation of protein metabolic process GO:0051246 56 0.024
wound healing GO:0042060 90 0.024
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
developmental programmed cell death GO:0010623 4 0.023
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.023
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
regulation of wound healing GO:0061041 2 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
larval development GO:0002164 2 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.022
somatic muscle development GO:0007525 4 0.022
programmed cell death GO:0012501 119 0.022
regulation of mitochondrion organization GO:0010821 1 0.022
cell projection organization GO:0030030 284 0.021
inner ear development GO:0048839 126 0.021
regulation of erk1 and erk2 cascade GO:0070372 4 0.021
single organism membrane fusion GO:0044801 2 0.021
immune response activating signal transduction GO:0002757 5 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
sensory organ development GO:0007423 393 0.021
regulation of cytokine mediated signaling pathway GO:0001959 3 0.021
striated muscle cell differentiation GO:0051146 129 0.020
regulation of cell killing GO:0031341 2 0.020
regulation of leukocyte mediated cytotoxicity GO:0001910 1 0.020
regulation of metal ion transport GO:0010959 4 0.020
response to drug GO:0042493 3 0.020
developmental growth involved in morphogenesis GO:0060560 86 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
response to topologically incorrect protein GO:0035966 2 0.020
brain development GO:0007420 293 0.020
regulation of cell death GO:0010941 103 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
multi organism process GO:0051704 134 0.019
cell migration involved in gastrulation GO:0042074 79 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of myotube differentiation GO:0010830 2 0.019
viral process GO:0016032 1 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
activation of mapk activity GO:0000187 3 0.019
multicellular organismal macromolecule metabolic process GO:0044259 2 0.019
modification by symbiont of host morphology or physiology GO:0044003 4 0.019
apoptotic process involved in morphogenesis GO:0060561 2 0.018
regulation of protein complex assembly GO:0043254 3 0.018
cell killing GO:0001906 2 0.018
cell projection morphogenesis GO:0048858 244 0.018
lateral inhibition GO:0046331 1 0.018
negative regulation of defense response GO:0031348 2 0.018
liver development GO:0001889 96 0.018
regulation of defense response GO:0031347 14 0.018
multicellular organism growth GO:0035264 4 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
cellular response to toxic substance GO:0097237 1 0.018
protein acylation GO:0043543 3 0.018
regulation of cell differentiation GO:0045595 142 0.018
negative regulation of immune response GO:0050777 2 0.018
regulation of interferon beta production GO:0032648 1 0.018
acylglycerol homeostasis GO:0055090 2 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
macromolecule modification GO:0043412 111 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
regulation of apoptotic process GO:0042981 98 0.018
ear development GO:0043583 127 0.017
cell death in response to oxidative stress GO:0036473 2 0.017
interaction with host GO:0051701 4 0.017
lymphangiogenesis GO:0001946 25 0.017
positive regulation of cell cycle GO:0045787 3 0.017
nitric oxide metabolic process GO:0046209 2 0.017
positive regulation of secretion GO:0051047 1 0.017
response to chemical GO:0042221 320 0.017
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.017
response to molecule of bacterial origin GO:0002237 14 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
protein import GO:0017038 3 0.017
positive regulation of translation GO:0045727 1 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
cellular protein modification process GO:0006464 100 0.017
antibacterial humoral response GO:0019731 2 0.016
positive regulation of muscle cell differentiation GO:0051149 1 0.016
regulation of cell shape GO:0008360 1 0.016
striated muscle cell development GO:0055002 108 0.016
single organism nuclear import GO:1902593 3 0.016
regulation of dna recombination GO:0000018 2 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
lymph vessel morphogenesis GO:0036303 25 0.016
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.015
regulation of synapse organization GO:0050807 3 0.015
cellular component movement GO:0006928 335 0.015
tyrosine phosphorylation of stat protein GO:0007260 1 0.015
regulation of response to stress GO:0080134 36 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
spermatid development GO:0007286 2 0.015
response to vitamin GO:0033273 3 0.015
leukocyte mediated cytotoxicity GO:0001909 1 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
regulation of signal transduction GO:0009966 225 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
stem cell differentiation GO:0048863 117 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of autophagy GO:0010506 3 0.015
defense response to bacterium GO:0042742 22 0.015
immune system development GO:0002520 191 0.014
gastrulation GO:0007369 208 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
cell death GO:0008219 121 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
cytokine metabolic process GO:0042107 1 0.014
regulation of innate immune response GO:0045088 11 0.014
protein localization to nucleus GO:0034504 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
retina development in camera type eye GO:0060041 146 0.014
regulation of gene expression GO:0010468 265 0.014
response to ketone GO:1901654 1 0.014
fatty acid biosynthetic process GO:0006633 4 0.014
cellular response to unfolded protein GO:0034620 2 0.014
regulation of binding GO:0051098 3 0.014
response to unfolded protein GO:0006986 2 0.014
response to corticosteroid GO:0031960 1 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
humoral immune response GO:0006959 5 0.013
cytokinesis GO:0000910 3 0.013
tissue regeneration GO:0042246 74 0.013
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.013
response to monosaccharide GO:0034284 3 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
autophagy GO:0006914 4 0.013
head development GO:0060322 303 0.013
maintenance of location GO:0051235 4 0.013
cell substrate adhesion GO:0031589 4 0.013
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
negative regulation of mitosis GO:0045839 3 0.013
regulation of cell communication GO:0010646 232 0.013
cellular response to retinoic acid GO:0071300 1 0.013
somatic stem cell maintenance GO:0035019 1 0.013
somatic cell dna recombination GO:0016444 1 0.013
nik nf kappab signaling GO:0038061 1 0.013
hatching GO:0035188 4 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
positive regulation of metabolic process GO:0009893 108 0.013
posterior lateral line development GO:0048916 38 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
positive regulation of defense response GO:0031349 9 0.013
mitochondrion organization GO:0007005 4 0.012
neuron development GO:0048666 262 0.012
t cell mediated immunity GO:0002456 1 0.012
response to hexose GO:0009746 3 0.012
negative regulation of cellular process GO:0048523 283 0.012
organism emergence from protective structure GO:0071684 4 0.012
organ regeneration GO:0031100 1 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
glucose import GO:0046323 2 0.012
muscle tissue development GO:0060537 110 0.012
cellular component disassembly GO:0022411 1 0.012
membrane invagination GO:0010324 1 0.012
regulation of cellular component movement GO:0051270 55 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
vasculogenesis GO:0001570 41 0.012
peptidyl serine modification GO:0018209 2 0.012
lateral line system development GO:0048925 76 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of cellular response to oxidative stress GO:1900407 2 0.012
defense response to virus GO:0051607 10 0.012
negative regulation of innate immune response GO:0045824 2 0.012
biosynthetic process GO:0009058 294 0.012
multi organism cellular process GO:0044764 2 0.012
protein heterooligomerization GO:0051291 1 0.012
regulation of protein targeting GO:1903533 2 0.012
regulation of translational initiation GO:0006446 1 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
astrocyte differentiation GO:0048708 1 0.012
long chain fatty acid biosynthetic process GO:0042759 1 0.012
intracellular signal transduction GO:0035556 85 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of cell development GO:0060284 100 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
regulation of lymphocyte mediated immunity GO:0002706 1 0.011
centrosome organization GO:0051297 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
apoptotic process GO:0006915 116 0.011
organelle assembly GO:0070925 110 0.011
camera type eye development GO:0043010 222 0.011
lymphocyte homeostasis GO:0002260 1 0.011
positive regulation of neuron death GO:1901216 1 0.011
endothelial cell migration GO:0043542 19 0.011
negative regulation of nuclear division GO:0051784 3 0.011
negative regulation of neuron projection regeneration GO:0070571 4 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
muscle structure development GO:0061061 196 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
positive regulation of inflammatory response GO:0050729 1 0.011
cytokine production involved in immune response GO:0002367 1 0.011
cytokine mediated signaling pathway GO:0019221 7 0.011
endosomal transport GO:0016197 2 0.011
centrosome duplication GO:0051298 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
exocytosis GO:0006887 1 0.011
leukocyte homeostasis GO:0001776 2 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
regulation of locomotion GO:0040012 55 0.011
regulation of calcium ion transport GO:0051924 2 0.011
rna metabolic process GO:0016070 219 0.011
protein import into nucleus GO:0006606 3 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
nucleic acid metabolic process GO:0090304 244 0.011
negative regulation of cellular protein metabolic process GO:0032269 16 0.011
localization of cell GO:0051674 244 0.011
spermatid differentiation GO:0048515 2 0.011
cellular response to endogenous stimulus GO:0071495 68 0.010
axonogenesis GO:0007409 152 0.010
response to carbohydrate GO:0009743 3 0.010
axon development GO:0061564 166 0.010
posterior lateral line neuromast hair cell development GO:0035677 3 0.010
protein modification process GO:0036211 100 0.010
homeostasis of number of cells GO:0048872 62 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.010
heterocycle metabolic process GO:0046483 290 0.010
atp catabolic process GO:0006200 4 0.010
regulation of protein catabolic process GO:0042176 1 0.010
hemopoiesis GO:0030097 183 0.010
transport GO:0006810 220 0.010
negative regulation of translation GO:0017148 1 0.010
regulation of oxidative stress induced cell death GO:1903201 2 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
single fertilization GO:0007338 3 0.010
myeloid cell development GO:0061515 32 0.010
meiosis i GO:0007127 1 0.010

c1qc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
lipid storage disease DOID:9455 0 0.016
lysosomal storage disease DOID:3211 0 0.016
inherited metabolic disorder DOID:655 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.015
motor neuron disease DOID:231 0 0.012
central nervous system disease DOID:331 0 0.012
amyotrophic lateral sclerosis DOID:332 0 0.012
neurodegenerative disease DOID:1289 0 0.012