Danio rerio

0 known processes

hectd3

HECT domain containing 3

(Aliases: zgc:153380,wu:fc38h02,KIAA0076,MGC153380)

hectd3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.150
cellular macromolecule metabolic process GO:0044260 391 0.133
signal transduction GO:0007165 455 0.125
aging GO:0007568 2 0.112
cellular protein catabolic process GO:0044257 4 0.097
neuron differentiation GO:0030182 353 0.096
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.088
generation of neurons GO:0048699 385 0.085
cellular nitrogen compound metabolic process GO:0034641 290 0.084
regulation of signaling GO:0023051 235 0.082
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.077
regulation of cell communication GO:0010646 232 0.075
maintenance of location GO:0051235 4 0.071
regulation of cellular metabolic process GO:0031323 320 0.067
cellular component morphogenesis GO:0032989 336 0.066
regulation of response to stimulus GO:0048583 269 0.064
lipid storage GO:0019915 1 0.063
positive regulation of biological process GO:0048518 253 0.062
ubiquitin dependent protein catabolic process GO:0006511 3 0.061
positive regulation of cellular component biogenesis GO:0044089 3 0.057
guanosine containing compound metabolic process GO:1901068 4 0.057
meiotic nuclear division GO:0007126 4 0.056
meiotic cell cycle process GO:1903046 3 0.055
proteasomal protein catabolic process GO:0010498 2 0.053
central nervous system development GO:0007417 387 0.053
modification dependent macromolecule catabolic process GO:0043632 3 0.051
head development GO:0060322 303 0.051
fatty acid catabolic process GO:0009062 1 0.046
regulation of cell death GO:0010941 103 0.046
establishment of protein localization to organelle GO:0072594 4 0.046
establishment of localization GO:0051234 244 0.046
phagocytosis GO:0006909 3 0.043
chordate embryonic development GO:0043009 271 0.042
intracellular signal transduction GO:0035556 85 0.041
single organism metabolic process GO:0044710 217 0.041
neuron development GO:0048666 262 0.041
negative regulation of biological process GO:0048519 304 0.040
gtp metabolic process GO:0046039 4 0.040
embryonic organ development GO:0048568 381 0.040
regulation of macromolecule metabolic process GO:0060255 317 0.039
lipid catabolic process GO:0016042 4 0.039
regulation of apoptotic process GO:0042981 98 0.039
nitrogen compound metabolic process GO:0006807 319 0.038
meiotic chromosome segregation GO:0045132 3 0.038
gastrulation GO:0007369 208 0.038
single organism localization GO:1902578 225 0.037
amine metabolic process GO:0009308 2 0.037
organic substance biosynthetic process GO:1901576 289 0.037
protein metabolic process GO:0019538 183 0.036
single organism transport GO:0044765 206 0.036
digestive system development GO:0055123 289 0.035
cellular amide metabolic process GO:0043603 4 0.035
cellular aromatic compound metabolic process GO:0006725 295 0.035
protein dephosphorylation GO:0006470 3 0.034
multicellular organism growth GO:0035264 4 0.034
oxoacid metabolic process GO:0043436 31 0.034
small molecule metabolic process GO:0044281 77 0.034
cellular lipid catabolic process GO:0044242 3 0.034
organic cyclic compound metabolic process GO:1901360 301 0.033
response to stress GO:0006950 263 0.033
regulation of biological quality GO:0065008 263 0.033
positive regulation of cellular process GO:0048522 201 0.032
small molecule catabolic process GO:0044282 3 0.032
adult behavior GO:0030534 2 0.032
gtp catabolic process GO:0006184 2 0.032
cellular amino acid metabolic process GO:0006520 7 0.032
modification dependent protein catabolic process GO:0019941 3 0.032
positive regulation of catabolic process GO:0009896 4 0.031
organelle organization GO:0006996 227 0.030
transport GO:0006810 220 0.030
heterocycle metabolic process GO:0046483 290 0.030
carboxylic acid catabolic process GO:0046395 3 0.029
neurotransmitter secretion GO:0007269 2 0.029
regulation of protein complex assembly GO:0043254 3 0.029
cell projection morphogenesis GO:0048858 244 0.029
digestive tract development GO:0048565 265 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
regulation of protein transport GO:0051223 3 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
regulation of synapse organization GO:0050807 3 0.028
glucose homeostasis GO:0042593 1 0.028
positive regulation of transport GO:0051050 2 0.028
regulation of protein catabolic process GO:0042176 1 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.027
locomotion GO:0040011 313 0.027
homeostatic process GO:0042592 142 0.027
regulation of programmed cell death GO:0043067 101 0.027
cell morphogenesis GO:0000902 289 0.026
endosomal transport GO:0016197 2 0.026
brain development GO:0007420 293 0.026
organic acid metabolic process GO:0006082 31 0.026
cell projection organization GO:0030030 284 0.025
regulation of metabolic process GO:0019222 359 0.025
blood vessel development GO:0001568 246 0.024
monocarboxylic acid catabolic process GO:0072329 3 0.024
negative regulation of cellular process GO:0048523 283 0.024
regulation of glucose import GO:0046324 1 0.024
protein secretion GO:0009306 1 0.024
cell part morphogenesis GO:0032990 246 0.024
tube morphogenesis GO:0035239 349 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
regulation of signal transduction GO:0009966 225 0.023
cellular catabolic process GO:0044248 27 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
neuron projection morphogenesis GO:0048812 161 0.023
peptide metabolic process GO:0006518 1 0.023
cellular biosynthetic process GO:0044249 286 0.023
regulation of multicellular organismal process GO:0051239 277 0.022
neuron projection development GO:0031175 180 0.022
cell death GO:0008219 121 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
anterior posterior pattern specification GO:0009952 152 0.022
regulation of cell matrix adhesion GO:0001952 1 0.022
phagocytosis engulfment GO:0006911 1 0.021
microtubule organizing center organization GO:0031023 1 0.021
proteolysis GO:0006508 38 0.021
neurotransmitter transport GO:0006836 2 0.021
death GO:0016265 121 0.021
cytokinesis GO:0000910 3 0.021
cellular amine metabolic process GO:0044106 2 0.021
skeletal system development GO:0001501 181 0.021
cellular protein metabolic process GO:0044267 129 0.021
immune system process GO:0002376 241 0.021
positive regulation of gtp catabolic process GO:0033126 1 0.021
organonitrogen compound metabolic process GO:1901564 74 0.020
protein polymerization GO:0051258 4 0.020
organism emergence from protective structure GO:0071684 4 0.020
membrane invagination GO:0010324 1 0.020
embryonic skeletal system development GO:0048706 97 0.020
cellular ketone metabolic process GO:0042180 11 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.020
morphogenesis of an epithelium GO:0002009 333 0.020
epithelial cell morphogenesis GO:0003382 2 0.020
golgi vesicle transport GO:0048193 3 0.020
protein localization GO:0008104 40 0.020
lipid oxidation GO:0034440 1 0.020
regulation of epithelial cell proliferation GO:0050678 3 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
positive regulation of gtpase activity GO:0043547 1 0.019
fatty acid beta oxidation GO:0006635 1 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
synaptic vesicle transport GO:0048489 1 0.019
axonogenesis GO:0007409 152 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
digestive tract morphogenesis GO:0048546 231 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
cellular modified amino acid metabolic process GO:0006575 3 0.018
regulation of developmental process GO:0050793 247 0.018
eye development GO:0001654 277 0.018
regulation of tube size GO:0035150 2 0.018
vasculature development GO:0001944 278 0.018
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.018
sensory organ development GO:0007423 393 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
organic acid catabolic process GO:0016054 3 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
neuromuscular process controlling balance GO:0050885 3 0.018
negative regulation of apoptotic process GO:0043066 55 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
centrosome organization GO:0051297 1 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
mitochondrion organization GO:0007005 4 0.018
regulation of metal ion transport GO:0010959 4 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
regulation of fatty acid metabolic process GO:0019217 1 0.018
synaptic transmission cholinergic GO:0007271 4 0.018
developmental growth GO:0048589 166 0.017
response to chemical GO:0042221 320 0.017
regulation of blood vessel size GO:0050880 2 0.017
regulation of primary metabolic process GO:0080090 311 0.017
appendage development GO:0048736 80 0.017
regionalization GO:0003002 274 0.017
blood vessel morphogenesis GO:0048514 216 0.017
positive regulation of cell cycle GO:0045787 3 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
synaptic vesicle localization GO:0097479 1 0.017
negative regulation of signaling GO:0023057 96 0.017
cognition GO:0050890 1 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
macroautophagy GO:0016236 1 0.017
protein import into nucleus GO:0006606 3 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
cellular component movement GO:0006928 335 0.017
female meiotic division GO:0007143 2 0.017
autophagy GO:0006914 4 0.016
notochord development GO:0030903 54 0.016
ion transport GO:0006811 114 0.016
regulation of ph GO:0006885 3 0.016
single organism organelle organization GO:1902589 199 0.016
centrosome cycle GO:0007098 1 0.016
carbohydrate homeostasis GO:0033500 1 0.016
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.016
regulation of gtpase activity GO:0043087 2 0.016
regulation of reproductive process GO:2000241 4 0.016
hormone transport GO:0009914 2 0.016
glycoprotein biosynthetic process GO:0009101 21 0.016
nucleic acid metabolic process GO:0090304 244 0.016
system process GO:0003008 185 0.016
b cell activation GO:0042113 2 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
regulation of blood pressure GO:0008217 1 0.016
negative regulation of cell death GO:0060548 60 0.016
programmed cell death GO:0012501 119 0.016
catabolic process GO:0009056 32 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.016
vacuolar transport GO:0007034 2 0.016
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.015
medulla oblongata development GO:0021550 4 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
regulation of synapse assembly GO:0051963 3 0.015
cell migration GO:0016477 237 0.015
cellular component biogenesis GO:0044085 178 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
liver development GO:0001889 96 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
organic substance catabolic process GO:1901575 28 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
positive regulation of blood circulation GO:1903524 2 0.015
regulation of protein polymerization GO:0032271 2 0.015
rna metabolic process GO:0016070 219 0.014
g2 dna damage checkpoint GO:0031572 3 0.014
positive regulation of glucose import GO:0046326 1 0.014
gene expression GO:0010467 252 0.014
stem cell proliferation GO:0072089 4 0.014
hatching GO:0035188 4 0.014
membrane fusion GO:0061025 2 0.014
regulation of sodium ion transport GO:0002028 2 0.014
cellular response to nutrient levels GO:0031669 2 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
taxis GO:0042330 109 0.014
cell cycle GO:0007049 93 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of cell activation GO:0050865 1 0.014
positive regulation of carbohydrate metabolic process GO:0045913 1 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
response to alkaloid GO:0043279 2 0.013
protein import GO:0017038 3 0.013
response to organic substance GO:0010033 153 0.013
protein localization to plasma membrane GO:0072659 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
growth GO:0040007 174 0.013
hormone secretion GO:0046879 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
actin filament based movement GO:0030048 1 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
adherens junction organization GO:0034332 4 0.013
regulation of gene expression GO:0010468 265 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
female gonad development GO:0008585 4 0.013
cation transmembrane transport GO:0098655 65 0.013
protein targeting to nucleus GO:0044744 3 0.013
response to corticosteroid GO:0031960 1 0.013
regulation of intracellular ph GO:0051453 1 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
negative regulation of catabolic process GO:0009895 3 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
pyrimidine containing compound metabolic process GO:0072527 3 0.013
nucleobase containing compound transport GO:0015931 2 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
positive regulation of secretion GO:0051047 1 0.013
establishment of localization in cell GO:0051649 77 0.013
cellular response to starvation GO:0009267 1 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
phagosome maturation GO:0090382 1 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
organic substance transport GO:0071702 58 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
macromolecule localization GO:0033036 54 0.012
regulation of cell shape GO:0008360 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
response to uv GO:0009411 3 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
nuclear transport GO:0051169 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
cell matrix adhesion GO:0007160 4 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of endocrine process GO:0044060 2 0.012
cell substrate adhesion GO:0031589 4 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
cell motility GO:0048870 244 0.012
homeostasis of number of cells GO:0048872 62 0.012
nucleic acid transport GO:0050657 2 0.012
protein modification process GO:0036211 100 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
regulation of neurogenesis GO:0050767 87 0.012
positive regulation of striated muscle cell differentiation GO:0051155 1 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
apoptotic process GO:0006915 116 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
exocytosis GO:0006887 1 0.011
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
negative regulation of defense response GO:0031348 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
dicarboxylic acid transport GO:0006835 1 0.011
sex determination GO:0007530 1 0.011
dna templated transcription elongation GO:0006354 3 0.011
response to nutrient GO:0007584 3 0.011
response to abiotic stimulus GO:0009628 122 0.011
protein targeting to vacuole GO:0006623 1 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
angiogenesis GO:0001525 158 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
epithelial cell differentiation GO:0030855 116 0.011
microtubule based movement GO:0007018 33 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
cellular response to external stimulus GO:0071496 2 0.011
regulation of organ growth GO:0046620 3 0.011
cellular response to radiation GO:0071478 4 0.011
leukocyte mediated cytotoxicity GO:0001909 1 0.011
actin filament polymerization GO:0030041 2 0.011
heart development GO:0007507 313 0.011
positive regulation of cell activation GO:0050867 1 0.011
intracellular mrna localization GO:0008298 1 0.011
cofactor biosynthetic process GO:0051188 10 0.011
negative regulation of chemotaxis GO:0050922 4 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
regulation of oocyte development GO:0060281 3 0.011
intracellular transport GO:0046907 32 0.011
locomotor rhythm GO:0045475 3 0.011
localization of cell GO:0051674 244 0.011
fatty acid oxidation GO:0019395 1 0.011
response to glucocorticoid GO:0051384 1 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
chemotaxis GO:0006935 104 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
golgi organization GO:0007030 1 0.011
endocrine process GO:0050886 2 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
anion transport GO:0006820 38 0.011
establishment of organelle localization GO:0051656 45 0.010
regulation of nervous system development GO:0051960 90 0.010
stem cell maintenance GO:0019827 4 0.010
lytic vacuole organization GO:0080171 1 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
establishment of protein localization to vacuole GO:0072666 1 0.010
hemopoiesis GO:0030097 183 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
tissue remodeling GO:0048771 4 0.010
ras protein signal transduction GO:0007265 7 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
embryonic hemopoiesis GO:0035162 53 0.010
gland development GO:0048732 143 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
single organism nuclear import GO:1902593 3 0.010
regulation of transporter activity GO:0032409 2 0.010
female sex differentiation GO:0046660 4 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
regulation of cell differentiation GO:0045595 142 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
alpha amino acid metabolic process GO:1901605 3 0.010
cartilage development GO:0051216 96 0.010

hectd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.016
disease of metabolism DOID:0014667 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
immune system disease DOID:2914 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
inherited metabolic disorder DOID:655 0 0.010