Danio rerio

0 known processes

hmbsa

hydroxymethylbilane synthase a

(Aliases: hmbs,MGC64128,zgc:64128)

hmbsa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.123
embryo development ending in birth or egg hatching GO:0009792 271 0.088
cellular aromatic compound metabolic process GO:0006725 295 0.086
aging GO:0007568 2 0.075
aromatic compound biosynthetic process GO:0019438 217 0.071
regulation of biological quality GO:0065008 263 0.061
signal transduction GO:0007165 455 0.059
cellular macromolecule biosynthetic process GO:0034645 224 0.056
transcription dna templated GO:0006351 181 0.056
regulation of primary metabolic process GO:0080090 311 0.052
positive regulation of cell cycle GO:0045787 3 0.052
establishment of protein localization to organelle GO:0072594 4 0.051
i kappab kinase nf kappab signaling GO:0007249 4 0.048
nitrogen compound metabolic process GO:0006807 319 0.047
heterocycle metabolic process GO:0046483 290 0.047
organic substance biosynthetic process GO:1901576 289 0.044
regulation of metabolic process GO:0019222 359 0.043
biosynthetic process GO:0009058 294 0.042
organic cyclic compound metabolic process GO:1901360 301 0.041
maintenance of location GO:0051235 4 0.041
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.041
single organism metabolic process GO:0044710 217 0.040
protein targeting to nucleus GO:0044744 3 0.038
nucleocytoplasmic transport GO:0006913 4 0.038
protein import into nucleus GO:0006606 3 0.037
locomotion GO:0040011 313 0.037
organelle organization GO:0006996 227 0.036
positive regulation of catabolic process GO:0009896 4 0.036
cellular protein catabolic process GO:0044257 4 0.036
macromolecule biosynthetic process GO:0009059 227 0.036
regulation of multicellular organismal development GO:2000026 223 0.035
gtp catabolic process GO:0006184 2 0.034
cellular nitrogen compound biosynthetic process GO:0044271 218 0.033
phagocytosis GO:0006909 3 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.032
tube morphogenesis GO:0035239 349 0.032
multicellular organism growth GO:0035264 4 0.031
positive regulation of metabolic process GO:0009893 108 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
regulation of cellular metabolic process GO:0031323 320 0.030
regulation of signal transduction GO:0009966 225 0.030
transport GO:0006810 220 0.029
cellular component morphogenesis GO:0032989 336 0.029
phosphate containing compound metabolic process GO:0006796 108 0.029
spindle assembly GO:0051225 2 0.029
negative regulation of biological process GO:0048519 304 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
positive regulation of transport GO:0051050 2 0.028
lipid storage GO:0019915 1 0.027
response to chemical GO:0042221 320 0.027
programmed cell death GO:0012501 119 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
cellular amine metabolic process GO:0044106 2 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.026
protein localization to nucleus GO:0034504 3 0.026
protein metabolic process GO:0019538 183 0.026
establishment of localization GO:0051234 244 0.026
stem cell proliferation GO:0072089 4 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
regulation of cell death GO:0010941 103 0.026
single fertilization GO:0007338 3 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.026
gtp metabolic process GO:0046039 4 0.026
response to stress GO:0006950 263 0.026
regulation of developmental process GO:0050793 247 0.025
female sex differentiation GO:0046660 4 0.025
protein secretion GO:0009306 1 0.025
amine metabolic process GO:0009308 2 0.025
female gonad development GO:0008585 4 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
nuclear import GO:0051170 3 0.024
single organism nuclear import GO:1902593 3 0.024
regulation of protein localization to nucleus GO:1900180 2 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
nucleic acid templated transcription GO:0097659 181 0.024
cell death GO:0008219 121 0.024
phosphorus metabolic process GO:0006793 109 0.024
cellular component movement GO:0006928 335 0.024
positive regulation of biological process GO:0048518 253 0.024
apoptotic process GO:0006915 116 0.023
rna biosynthetic process GO:0032774 181 0.023
small molecule metabolic process GO:0044281 77 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
cell part morphogenesis GO:0032990 246 0.023
regulation of synapse organization GO:0050807 3 0.022
immune system development GO:0002520 191 0.022
protein import GO:0017038 3 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.022
nucleic acid metabolic process GO:0090304 244 0.022
adult behavior GO:0030534 2 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
regulation of cytokine production GO:0001817 3 0.022
cellular biosynthetic process GO:0044249 286 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
multi organism process GO:0051704 134 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
regulation of cell communication GO:0010646 232 0.021
oxoacid metabolic process GO:0043436 31 0.021
regulation of rna metabolic process GO:0051252 224 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
mitochondrion organization GO:0007005 4 0.021
cellular ketone metabolic process GO:0042180 11 0.020
regulation of signaling GO:0023051 235 0.020
death GO:0016265 121 0.020
organic acid metabolic process GO:0006082 31 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
regulation of wound healing GO:0061041 2 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
single organism organelle organization GO:1902589 199 0.020
localization of cell GO:0051674 244 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
vasculature development GO:0001944 278 0.019
stem cell maintenance GO:0019827 4 0.019
regulation of biosynthetic process GO:0009889 250 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
centrosome duplication GO:0051298 1 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
zymogen activation GO:0031638 3 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
centrosome cycle GO:0007098 1 0.019
regulation of programmed cell death GO:0043067 101 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
regulation of gene expression GO:0010468 265 0.018
immune system process GO:0002376 241 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
cytokinesis GO:0000910 3 0.018
gene expression GO:0010467 252 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
anterior posterior pattern specification GO:0009952 152 0.018
atp catabolic process GO:0006200 4 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of apoptotic process GO:0042981 98 0.018
phosphorylation GO:0016310 69 0.018
regulation of synapse assembly GO:0051963 3 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
meiotic cell cycle process GO:1903046 3 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
digestive tract morphogenesis GO:0048546 231 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of transcription dna templated GO:0006355 213 0.017
regulation of binding GO:0051098 3 0.017
meiotic nuclear division GO:0007126 4 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
cellular component disassembly GO:0022411 1 0.017
nuclear migration GO:0007097 3 0.017
neurological system process GO:0050877 62 0.017
actin polymerization or depolymerization GO:0008154 2 0.017
regulation of molecular function GO:0065009 70 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
nuclear transport GO:0051169 4 0.017
regulation of neurotransmitter transport GO:0051588 1 0.017
regulation of cell shape GO:0008360 1 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
angiogenesis GO:0001525 158 0.016
positive regulation of translation GO:0045727 1 0.016
cellular component assembly GO:0022607 170 0.016
leukocyte proliferation GO:0070661 1 0.016
regulation of protein binding GO:0043393 3 0.016
cell projection organization GO:0030030 284 0.016
cell cell recognition GO:0009988 1 0.016
oocyte maturation GO:0001556 4 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
positive regulation of secretion GO:0051047 1 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
regulation of protein transport GO:0051223 3 0.016
cellular response to oxygen levels GO:0071453 1 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
system process GO:0003008 185 0.015
regulation of protein targeting GO:1903533 2 0.015
gastrulation GO:0007369 208 0.015
negative regulation of protein import into nucleus GO:0042308 2 0.015
cell proliferation GO:0008283 80 0.015
secondary metabolic process GO:0019748 3 0.015
digestive tract development GO:0048565 265 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
tissue remodeling GO:0048771 4 0.015
single organism biosynthetic process GO:0044711 71 0.015
cellular component biogenesis GO:0044085 178 0.015
cell projection morphogenesis GO:0048858 244 0.015
regulation of macromolecule biosynthetic process GO:0010556 225 0.015
response to drug GO:0042493 3 0.015
protein localization to plasma membrane GO:0072659 1 0.015
meiotic chromosome segregation GO:0045132 3 0.015
response to external stimulus GO:0009605 264 0.015
embryonic organ development GO:0048568 381 0.015
negative regulation of cell communication GO:0010648 96 0.015
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
neurotransmitter transport GO:0006836 2 0.014
cellular protein modification process GO:0006464 100 0.014
response to uv GO:0009411 3 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
protein polymerization GO:0051258 4 0.014
response to carbohydrate GO:0009743 3 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
exocytosis GO:0006887 1 0.014
protein heterooligomerization GO:0051291 1 0.014
regulation of protein complex assembly GO:0043254 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
positive regulation of cellular process GO:0048522 201 0.014
positive regulation of cytokine production GO:0001819 2 0.014
regulation of membrane potential GO:0042391 23 0.014
fertilization GO:0009566 3 0.014
single organism localization GO:1902578 225 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
response to abiotic stimulus GO:0009628 122 0.014
post embryonic morphogenesis GO:0009886 4 0.014
negative regulation of cellular process GO:0048523 283 0.013
regulation of reproductive process GO:2000241 4 0.013
digestive system development GO:0055123 289 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
cell morphogenesis GO:0000902 289 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of response to stimulus GO:0048583 269 0.013
peptidyl serine modification GO:0018209 2 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
brain development GO:0007420 293 0.013
regulation of protein catabolic process GO:0042176 1 0.013
regulation of myotube differentiation GO:0010830 2 0.013
single organism transport GO:0044765 206 0.013
spindle assembly involved in mitosis GO:0090307 1 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
chemosensory behavior GO:0007635 1 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
blood vessel development GO:0001568 246 0.013
b cell activation GO:0042113 2 0.013
head development GO:0060322 303 0.013
centrosome organization GO:0051297 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
central nervous system development GO:0007417 387 0.013
rna metabolic process GO:0016070 219 0.012
heart development GO:0007507 313 0.012
cellular response to nutrient levels GO:0031669 2 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
response to nutrient GO:0007584 3 0.012
muscle structure development GO:0061061 196 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
response to glucocorticoid GO:0051384 1 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
negative regulation of cytokine production GO:0001818 1 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
mononuclear cell proliferation GO:0032943 1 0.012
chordate embryonic development GO:0043009 271 0.012
amino acid transport GO:0006865 2 0.012
cell migration GO:0016477 237 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
cell cycle arrest GO:0007050 1 0.012
regulation of chromosome segregation GO:0051983 1 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
determination of left right symmetry GO:0007368 179 0.012
regionalization GO:0003002 274 0.012
response to corticosteroid GO:0031960 1 0.012
spermatid development GO:0007286 2 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
mitotic cytokinesis GO:0000281 3 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
protein complex disassembly GO:0043241 1 0.012
macromolecule modification GO:0043412 111 0.012
post embryonic organ development GO:0048569 4 0.012
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
regulation of receptor activity GO:0010469 2 0.011
cognition GO:0050890 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
cellular response to radiation GO:0071478 4 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
sister chromatid cohesion GO:0007062 2 0.011
regulation of blood pressure GO:0008217 1 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
microtubule polymerization or depolymerization GO:0031109 3 0.011
regulation of cell activation GO:0050865 1 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
negative regulation of signal transduction GO:0009968 94 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
macromolecular complex disassembly GO:0032984 1 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
spermatid differentiation GO:0048515 2 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
activation of mapk activity GO:0000187 3 0.011
microtubule based process GO:0007017 60 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
cell motility GO:0048870 244 0.011
cellular response to hypoxia GO:0071456 1 0.011
taxis GO:0042330 109 0.011
homeostatic process GO:0042592 142 0.011
muscle cell development GO:0055001 115 0.011
lymphocyte proliferation GO:0046651 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
regulation of exocytosis GO:0017157 1 0.011
organelle localization GO:0051640 49 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
endocrine process GO:0050886 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
cellular response to stress GO:0033554 62 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
cellular response to light stimulus GO:0071482 4 0.010
adherens junction organization GO:0034332 4 0.010
compound eye development GO:0048749 2 0.010
neurotransmitter secretion GO:0007269 2 0.010
regulation of dna templated transcription in response to stress GO:0043620 0 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
regulation of blood vessel size GO:0050880 2 0.010
blood vessel morphogenesis GO:0048514 216 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
proximal distal pattern formation GO:0009954 1 0.010
carbohydrate homeostasis GO:0033500 1 0.010
muscle tissue development GO:0060537 110 0.010
regulation of metal ion transport GO:0010959 4 0.010
regulation of mesenchymal cell proliferation GO:0010464 1 0.010
blood circulation GO:0008015 87 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010

hmbsa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.017