Danio rerio

0 known processes

dbr1

debranching enzyme homolog 1 (S. cerevisiae)

(Aliases: zgc:63930,wu:fc08f08)

dbr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.206
cellular macromolecule metabolic process GO:0044260 391 0.167
regulation of macromolecule metabolic process GO:0060255 317 0.144
gene expression GO:0010467 252 0.123
cellular nitrogen compound metabolic process GO:0034641 290 0.123
nitrogen compound metabolic process GO:0006807 319 0.115
nucleic acid metabolic process GO:0090304 244 0.112
regulation of nitrogen compound metabolic process GO:0051171 251 0.108
rna metabolic process GO:0016070 219 0.105
nucleobase containing compound metabolic process GO:0006139 274 0.104
regulation of mrna splicing via spliceosome GO:0048024 3 0.099
nuclear transport GO:0051169 4 0.098
cellular macromolecule biosynthetic process GO:0034645 224 0.098
negative regulation of cellular process GO:0048523 283 0.098
cellular aromatic compound metabolic process GO:0006725 295 0.094
regulation of gene expression GO:0010468 265 0.090
stem cell maintenance GO:0019827 4 0.086
organic cyclic compound metabolic process GO:1901360 301 0.083
regulation of metabolic process GO:0019222 359 0.076
rna localization GO:0006403 4 0.074
response to stress GO:0006950 263 0.071
nucleic acid templated transcription GO:0097659 181 0.068
heterocycle metabolic process GO:0046483 290 0.068
nucleocytoplasmic transport GO:0006913 4 0.066
cellular component movement GO:0006928 335 0.066
regulation of transcription dna templated GO:0006355 213 0.066
negative regulation of biological process GO:0048519 304 0.065
modification dependent protein catabolic process GO:0019941 3 0.065
cellular nitrogen compound biosynthetic process GO:0044271 218 0.060
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.059
aromatic compound biosynthetic process GO:0019438 217 0.059
regulation of rna metabolic process GO:0051252 224 0.059
embryo development ending in birth or egg hatching GO:0009792 271 0.057
Worm
generation of neurons GO:0048699 385 0.056
regulation of macromolecule biosynthetic process GO:0010556 225 0.053
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.052
response to chemical GO:0042221 320 0.051
rna processing GO:0006396 25 0.050
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.050
cellular protein catabolic process GO:0044257 4 0.050
nuclear export GO:0051168 1 0.048
phagocytosis GO:0006909 3 0.047
regulation of rna biosynthetic process GO:2001141 213 0.047
protein acetylation GO:0006473 2 0.047
regulation of cellular biosynthetic process GO:0031326 245 0.046
cellular biosynthetic process GO:0044249 286 0.046
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.046
cellular component morphogenesis GO:0032989 336 0.045
regulation of primary metabolic process GO:0080090 311 0.045
stem cell proliferation GO:0072089 4 0.044
transcription dna templated GO:0006351 181 0.044
negative regulation of stem cell differentiation GO:2000737 2 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.043
mrna export from nucleus GO:0006406 1 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.041
regulation of cellular metabolic process GO:0031323 320 0.040
cellular component assembly GO:0022607 170 0.040
cellular component biogenesis GO:0044085 178 0.040
protein localization to plasma membrane GO:0072659 1 0.038
macromolecule biosynthetic process GO:0009059 227 0.037
protein acylation GO:0043543 3 0.037
regulation of stem cell proliferation GO:0072091 2 0.037
cell morphogenesis GO:0000902 289 0.036
response to external stimulus GO:0009605 264 0.036
protein localization to nucleus GO:0034504 3 0.036
rna export from nucleus GO:0006405 1 0.035
rna transport GO:0050658 2 0.035
alternative mrna splicing via spliceosome GO:0000380 1 0.035
cellular protein metabolic process GO:0044267 129 0.035
biosynthetic process GO:0009058 294 0.034
positive regulation of biological process GO:0048518 253 0.034
regulation of apoptotic process GO:0042981 98 0.033
heterocycle biosynthetic process GO:0018130 215 0.033
mitotic g2 m transition checkpoint GO:0044818 3 0.032
regulation of protein ubiquitination GO:0031396 3 0.032
multicellular organism growth GO:0035264 4 0.032
cell death GO:0008219 121 0.032
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
regulation of meiotic cell cycle GO:0051445 1 0.031
protein dephosphorylation GO:0006470 3 0.031
nucleic acid transport GO:0050657 2 0.031
positive regulation of map kinase activity GO:0043406 3 0.031
regulation of developmental process GO:0050793 247 0.031
positive regulation of cell cycle GO:0045787 3 0.031
rna splicing GO:0008380 16 0.030
regulation of cell differentiation GO:0045595 142 0.030
organelle assembly GO:0070925 110 0.030
establishment of rna localization GO:0051236 3 0.030
cytokinesis GO:0000910 3 0.030
gastrulation GO:0007369 208 0.030
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.029
g2 dna damage checkpoint GO:0031572 3 0.029
macromolecule modification GO:0043412 111 0.029
regulation of autophagy GO:0010506 3 0.029
transport GO:0006810 220 0.029
Worm
morphogenesis of an epithelium GO:0002009 333 0.029
positive regulation of cellular biosynthetic process GO:0031328 68 0.029
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
regionalization GO:0003002 274 0.028
cellular response to nutrient levels GO:0031669 2 0.028
axon development GO:0061564 166 0.027
regulation of cell death GO:0010941 103 0.027
regulation of nucleic acid templated transcription GO:1903506 213 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
neuroblast proliferation GO:0007405 2 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
mrna transport GO:0051028 2 0.027
regulation of neural precursor cell proliferation GO:2000177 3 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
response to hexose GO:0009746 3 0.027
establishment of localization GO:0051234 244 0.027
Worm
cellular response to external stimulus GO:0071496 2 0.027
spliceosomal snrnp assembly GO:0000387 2 0.027
proteasomal protein catabolic process GO:0010498 2 0.026
mitotic dna damage checkpoint GO:0044773 4 0.026
regulation of cytokine production GO:0001817 3 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
protein stabilization GO:0050821 2 0.026
signal transduction GO:0007165 455 0.026
single organism metabolic process GO:0044710 217 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.026
positive regulation of catabolic process GO:0009896 4 0.026
neuron projection morphogenesis GO:0048812 161 0.026
regulation of biosynthetic process GO:0009889 250 0.026
protein metabolic process GO:0019538 183 0.025
stem cell division GO:0017145 1 0.025
neuron differentiation GO:0030182 353 0.025
chemotaxis GO:0006935 104 0.025
chordate embryonic development GO:0043009 271 0.025
regulation of epithelial cell proliferation GO:0050678 3 0.025
nucleobase containing compound transport GO:0015931 2 0.025
aging GO:0007568 2 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.024
sensory organ development GO:0007423 393 0.024
nuclear import GO:0051170 3 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
localization of cell GO:0051674 244 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
rna biosynthetic process GO:0032774 181 0.024
regulation of programmed cell death GO:0043067 101 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
ameboidal type cell migration GO:0001667 143 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
mitotic cell cycle process GO:1903047 48 0.023
cell cycle g1 s phase transition GO:0044843 1 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
apoptotic process GO:0006915 116 0.022
cell part morphogenesis GO:0032990 246 0.022
cell cycle GO:0007049 93 0.022
protein modification process GO:0036211 100 0.022
positive regulation of cellular process GO:0048522 201 0.022
neuron projection development GO:0031175 180 0.021
mrna metabolic process GO:0016071 20 0.021
positive regulation of rna biosynthetic process GO:1902680 57 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
regulation of dendrite development GO:0050773 3 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
positive regulation of gene expression GO:0010628 71 0.021
response to abiotic stimulus GO:0009628 122 0.021
regulation of mrna processing GO:0050684 3 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
multi organism cellular process GO:0044764 2 0.021
negative regulation of cytokine production GO:0001818 1 0.021
regulation of response to nutrient levels GO:0032107 1 0.021
positive regulation of rna metabolic process GO:0051254 59 0.021
protein import into nucleus GO:0006606 3 0.020
rna 3 end processing GO:0031123 2 0.020
negative regulation of catabolic process GO:0009895 3 0.020
cellular amine metabolic process GO:0044106 2 0.020
single organism nuclear import GO:1902593 3 0.020
cell motility GO:0048870 244 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
cellular response to starvation GO:0009267 1 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
response to biotic stimulus GO:0009607 97 0.019
negative regulation of nuclear division GO:0051784 3 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
stem cell development GO:0048864 82 0.019
positive regulation of nucleic acid templated transcription GO:1903508 57 0.019
cellular response to biotic stimulus GO:0071216 3 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
neuron development GO:0048666 262 0.019
stem cell differentiation GO:0048863 117 0.019
cell migration GO:0016477 237 0.019
liver development GO:0001889 96 0.019
negative regulation of cell communication GO:0010648 96 0.019
neuron projection guidance GO:0097485 86 0.019
mitotic dna integrity checkpoint GO:0044774 4 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
cell projection organization GO:0030030 284 0.019
somatic stem cell maintenance GO:0035019 1 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
rna polyadenylation GO:0043631 2 0.018
lateral inhibition GO:0046331 1 0.018
negative regulation of cell death GO:0060548 60 0.018
response to uv GO:0009411 3 0.018
negative regulation of defense response GO:0031348 2 0.018
programmed cell death GO:0012501 119 0.018
tube morphogenesis GO:0035239 349 0.018
multi organism process GO:0051704 134 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
positive regulation of biosynthetic process GO:0009891 68 0.018
taxis GO:0042330 109 0.018
death GO:0016265 121 0.018
regulation of protein metabolic process GO:0051246 56 0.018
axonogenesis GO:0007409 152 0.018
female gonad development GO:0008585 4 0.018
digestive tract development GO:0048565 265 0.018
specification of organ identity GO:0010092 2 0.018
positive regulation of transcription dna templated GO:0045893 57 0.018
cell projection morphogenesis GO:0048858 244 0.017
protein import GO:0017038 3 0.017
digestive system development GO:0055123 289 0.017
lipid storage GO:0019915 1 0.017
locomotor rhythm GO:0045475 3 0.017
sex determination GO:0007530 1 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
locomotion GO:0040011 313 0.017
Worm
wnt signaling pathway GO:0016055 80 0.017
maintenance of location GO:0051235 4 0.017
digestive tract morphogenesis GO:0048546 231 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
positive regulation of metabolic process GO:0009893 108 0.017
regulation of cell activation GO:0050865 1 0.017
response to nutrient GO:0007584 3 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
positive regulation of transport GO:0051050 2 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.016
cell projection assembly GO:0030031 64 0.016
regulation of cellular protein catabolic process GO:1903362 1 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
organism emergence from protective structure GO:0071684 4 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
synaptic target recognition GO:0008039 1 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
cellular protein modification process GO:0006464 100 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
mitotic g2 dna damage checkpoint GO:0007095 3 0.016
organic acid metabolic process GO:0006082 31 0.016
axon guidance GO:0007411 86 0.016
cellular localization GO:0051641 97 0.016
positive regulation of jun kinase activity GO:0043507 2 0.016
regulation of protein catabolic process GO:0042176 1 0.016
negative regulation of chromosome organization GO:2001251 1 0.016
meiotic nuclear division GO:0007126 4 0.015
convergent extension GO:0060026 118 0.015
regulation of biological quality GO:0065008 263 0.015
gtp catabolic process GO:0006184 2 0.015
single organism localization GO:1902578 225 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
amine metabolic process GO:0009308 2 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of chromosome segregation GO:0051983 1 0.015
carbohydrate homeostasis GO:0033500 1 0.015
viral process GO:0016032 1 0.015
regulation of binding GO:0051098 3 0.015
adult behavior GO:0030534 2 0.015
activation of mapk activity GO:0000187 3 0.015
response to ketone GO:1901654 1 0.015
negative regulation of developmental process GO:0051093 65 0.015
small molecule metabolic process GO:0044281 77 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
negative regulation of kinase activity GO:0033673 4 0.014
gland development GO:0048732 143 0.014
regulation of molecular function GO:0065009 70 0.014
organic substance biosynthetic process GO:1901576 289 0.014
response to monosaccharide GO:0034284 3 0.014
negative regulation of neural precursor cell proliferation GO:2000178 1 0.014
negative regulation of immune response GO:0050777 2 0.014
behavior GO:0007610 74 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
response to bacterium GO:0009617 58 0.014
peptide metabolic process GO:0006518 1 0.014
sister chromatid cohesion GO:0007062 2 0.014
regulation of synapse organization GO:0050807 3 0.014
positive regulation of muscle tissue development GO:1901863 1 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
response to external biotic stimulus GO:0043207 97 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
cellular amide metabolic process GO:0043603 4 0.014
single organism organelle organization GO:1902589 199 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
nuclear envelope organization GO:0006998 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
cognition GO:0050890 1 0.013
positive regulation of cytokine production GO:0001819 2 0.013
regulation of response to stimulus GO:0048583 269 0.013
organelle organization GO:0006996 227 0.013
regulation of cell development GO:0060284 100 0.013
intracellular mrna localization GO:0008298 1 0.013
autophagy GO:0006914 4 0.013
central nervous system development GO:0007417 387 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
mesenchyme development GO:0060485 127 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
b cell activation GO:0042113 2 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
cytoskeleton organization GO:0007010 96 0.013
interspecies interaction between organisms GO:0044419 4 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
negative chemotaxis GO:0050919 1 0.013
regulation of cell projection assembly GO:0060491 4 0.013
response to drug GO:0042493 3 0.013
developmental growth GO:0048589 166 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
regulation of reproductive process GO:2000241 4 0.013
tissue remodeling GO:0048771 4 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
response to carbohydrate GO:0009743 3 0.013
sleep GO:0030431 1 0.013
somite development GO:0061053 96 0.013
regulation of protein transport GO:0051223 3 0.013
response to amino acid GO:0043200 2 0.012
somatic muscle development GO:0007525 4 0.012
positive regulation of immune effector process GO:0002699 3 0.012
cellular ketone metabolic process GO:0042180 11 0.012
lamellipodium assembly GO:0030032 1 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
chromosome organization involved in meiosis GO:0070192 1 0.012
cell cycle arrest GO:0007050 1 0.012
eye development GO:0001654 277 0.012
negative regulation of mitosis GO:0045839 3 0.012
glucose import GO:0046323 2 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
lamellipodium organization GO:0097581 1 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
hepaticobiliary system development GO:0061008 98 0.012
chemosensory behavior GO:0007635 1 0.012
regulation of glucose transport GO:0010827 1 0.012
mitotic cell cycle GO:0000278 64 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
transcription from rna polymerase iii promoter GO:0006383 1 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
gtp metabolic process GO:0046039 4 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
mrna polyadenylation GO:0006378 2 0.012
negative regulation of mitotic cell cycle GO:0045930 11 0.012
regulation of jun kinase activity GO:0043506 3 0.012
cell matrix adhesion GO:0007160 4 0.012
cellular response to dsrna GO:0071359 1 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
response to other organism GO:0051707 97 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
vasculature development GO:0001944 278 0.011
regulation of signaling GO:0023051 235 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
segmentation GO:0035282 97 0.011
peptidyl serine modification GO:0018209 2 0.011
protein heterooligomerization GO:0051291 1 0.011
single organism membrane fusion GO:0044801 2 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
growth GO:0040007 174 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
regulation of protein complex assembly GO:0043254 3 0.011
system process GO:0003008 185 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
skin development GO:0043588 54 0.011
antimicrobial humoral response GO:0019730 2 0.011
phagocytosis engulfment GO:0006911 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
oxoacid metabolic process GO:0043436 31 0.011
membrane fusion GO:0061025 2 0.011
mrna splicing via spliceosome GO:0000398 10 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
anterior posterior pattern specification GO:0009952 152 0.011
response to glucose GO:0009749 3 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
mrna 3 end processing GO:0031124 2 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
protein polyubiquitination GO:0000209 4 0.011
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.011
cell substrate junction assembly GO:0007044 2 0.011
compound eye development GO:0048749 2 0.011
cartilage development GO:0051216 96 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
heart development GO:0007507 313 0.011
mrna processing GO:0006397 14 0.011
endosomal transport GO:0016197 2 0.011
response to organic substance GO:0010033 153 0.011
epidermis development GO:0008544 48 0.011
regulation of synapse assembly GO:0051963 3 0.011
regulation of inflammatory response GO:0050727 2 0.010
female sex differentiation GO:0046660 4 0.010
regulation of protein binding GO:0043393 3 0.010
connective tissue development GO:0061448 99 0.010
positive regulation of striated muscle tissue development GO:0045844 1 0.010
negative regulation of translation GO:0017148 1 0.010
cilium morphogenesis GO:0060271 85 0.010
negative regulation of innate immune response GO:0045824 2 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
regulation of translational initiation GO:0006446 1 0.010
hormone transport GO:0009914 2 0.010
microtubule organizing center organization GO:0031023 1 0.010
multi organism reproductive process GO:0044703 36 0.010
regulation of organ growth GO:0046620 3 0.010
skeletal system development GO:0001501 181 0.010

dbr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010