Danio rerio

0 known processes

mhc2dcb

major histocompatibility complex class II DCB gene

mhc2dcb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hematopoietic or lymphoid organ development GO:0048534 191 0.163
immune system process GO:0002376 241 0.131
larval development GO:0002164 2 0.112
eye development GO:0001654 277 0.108
cell surface receptor signaling pathway GO:0007166 325 0.094
aging GO:0007568 2 0.085
cellular aromatic compound metabolic process GO:0006725 295 0.080
single organism transport GO:0044765 206 0.079
regulation of multicellular organismal process GO:0051239 277 0.079
response to chemical GO:0042221 320 0.077
camera type eye development GO:0043010 222 0.077
embryonic organ development GO:0048568 381 0.077
gene expression GO:0010467 252 0.077
organonitrogen compound metabolic process GO:1901564 74 0.077
cellular macromolecule metabolic process GO:0044260 391 0.076
regionalization GO:0003002 274 0.074
response to stress GO:0006950 263 0.068
positive regulation of response to stimulus GO:0048584 80 0.065
blood vessel morphogenesis GO:0048514 216 0.065
signal transduction GO:0007165 455 0.065
single organism localization GO:1902578 225 0.063
neuron differentiation GO:0030182 353 0.062
heterocycle biosynthetic process GO:0018130 215 0.061
chordate embryonic development GO:0043009 271 0.059
regulation of primary metabolic process GO:0080090 311 0.058
ion transmembrane transport GO:0034220 91 0.054
regulation of circadian rhythm GO:0042752 4 0.053
regulation of metabolic process GO:0019222 359 0.052
nucleobase containing compound metabolic process GO:0006139 274 0.051
vasculature development GO:0001944 278 0.051
embryonic hemopoiesis GO:0035162 53 0.049
fin development GO:0033333 77 0.049
nitrogen compound metabolic process GO:0006807 319 0.047
maintenance of location GO:0051235 4 0.045
sensory organ morphogenesis GO:0090596 200 0.043
transmembrane transport GO:0055085 120 0.043
embryo development ending in birth or egg hatching GO:0009792 271 0.043
regulation of anatomical structure morphogenesis GO:0022603 130 0.041
hatching GO:0035188 4 0.040
sensory organ development GO:0007423 393 0.040
organic cyclic compound metabolic process GO:1901360 301 0.039
dorsal ventral pattern formation GO:0009953 125 0.039
regulation of macromolecule biosynthetic process GO:0010556 225 0.039
establishment of localization GO:0051234 244 0.039
heterocycle metabolic process GO:0046483 290 0.038
organic cyclic compound biosynthetic process GO:1901362 223 0.038
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.037
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
regulation of systemic arterial blood pressure GO:0003073 1 0.037
secondary metabolic process GO:0019748 3 0.036
regulation of blood pressure GO:0008217 1 0.035
homeostatic process GO:0042592 142 0.035
regulation of biological quality GO:0065008 263 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.033
muscle cell differentiation GO:0042692 139 0.032
embryonic organ morphogenesis GO:0048562 274 0.032
multicellular organism growth GO:0035264 4 0.031
regulation of transcription dna templated GO:0006355 213 0.031
sleep GO:0030431 1 0.031
generation of neurons GO:0048699 385 0.029
negative regulation of cellular process GO:0048523 283 0.029
response to wounding GO:0009611 116 0.028
central nervous system development GO:0007417 387 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
regulation of localization GO:0032879 104 0.028
transcription dna templated GO:0006351 181 0.027
regulation of inflammatory response GO:0050727 2 0.027
regulation of rna metabolic process GO:0051252 224 0.027
transport GO:0006810 220 0.027
head development GO:0060322 303 0.027
specification of symmetry GO:0009799 204 0.027
embryonic skeletal system morphogenesis GO:0048704 93 0.026
response to organic substance GO:0010033 153 0.026
cell cell signaling GO:0007267 52 0.025
ribonucleotide biosynthetic process GO:0009260 20 0.025
positive regulation of multicellular organismal process GO:0051240 52 0.025
regulation of cell communication GO:0010646 232 0.025
regulation of cell development GO:0060284 100 0.024
regulation of metal ion transport GO:0010959 4 0.024
pigmentation GO:0043473 85 0.023
organism emergence from protective structure GO:0071684 4 0.023
regulation of transmembrane transporter activity GO:0022898 2 0.023
regulation of transporter activity GO:0032409 2 0.023
single organism metabolic process GO:0044710 217 0.023
regulation of developmental process GO:0050793 247 0.023
cellular localization GO:0051641 97 0.023
blood vessel development GO:0001568 246 0.022
nucleic acid templated transcription GO:0097659 181 0.022
immune system development GO:0002520 191 0.022
regulation of cell activation GO:0050865 1 0.022
regulation of biosynthetic process GO:0009889 250 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.021
system process GO:0003008 185 0.021
circadian sleep wake cycle GO:0042745 2 0.021
response to external stimulus GO:0009605 264 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.020
organelle organization GO:0006996 227 0.020
mononuclear cell proliferation GO:0032943 1 0.020
regulation of cell differentiation GO:0045595 142 0.020
regulation of response to stimulus GO:0048583 269 0.020
cation transmembrane transport GO:0098655 65 0.020
regulation of gene expression GO:0010468 265 0.020
retina development in camera type eye GO:0060041 146 0.020
biosynthetic process GO:0009058 294 0.020
regulation of blood vessel size GO:0050880 2 0.020
positive regulation of catabolic process GO:0009896 4 0.019
negative regulation of cellular metabolic process GO:0031324 77 0.019
neuron projection development GO:0031175 180 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
determination of bilateral symmetry GO:0009855 204 0.019
positive regulation of heart contraction GO:0045823 2 0.019
cell motility GO:0048870 244 0.019
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.019
membrane repolarization GO:0086009 2 0.019
neuron development GO:0048666 262 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.018
cell projection organization GO:0030030 284 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
synaptic transmission cholinergic GO:0007271 4 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
positive regulation of cellular process GO:0048522 201 0.017
regulation of nervous system development GO:0051960 90 0.017
negative regulation of nuclear division GO:0051784 3 0.017
digestive system development GO:0055123 289 0.017
regulation of circadian sleep wake cycle GO:0042749 1 0.017
cation transport GO:0006812 81 0.017
cyclic purine nucleotide metabolic process GO:0052652 18 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
ovulation cycle GO:0042698 2 0.017
positive regulation of immune effector process GO:0002699 3 0.017
negative regulation of biological process GO:0048519 304 0.017
regulation of ion transmembrane transport GO:0034765 18 0.017
cellular response to unfolded protein GO:0034620 2 0.017
oxidoreduction coenzyme metabolic process GO:0006733 1 0.017
regulation of signaling GO:0023051 235 0.017
regulation of ion transport GO:0043269 22 0.017
regulation of establishment of protein localization GO:0070201 4 0.016
negative regulation of defense response GO:0031348 2 0.016
cellular ketone metabolic process GO:0042180 11 0.016
ion transport GO:0006811 114 0.016
oxoacid metabolic process GO:0043436 31 0.016
er nucleus signaling pathway GO:0006984 2 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
regulation of transmembrane transport GO:0034762 18 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
epithelial cell differentiation GO:0030855 116 0.016
photoreceptor cell differentiation GO:0046530 55 0.016
hemopoiesis GO:0030097 183 0.016
circadian sleep wake cycle process GO:0022410 2 0.016
neurological system process GO:0050877 62 0.015
b cell activation GO:0042113 2 0.015
developmental growth GO:0048589 166 0.015
determination of ventral identity GO:0048264 21 0.015
circadian sleep wake cycle sleep GO:0050802 1 0.015
neuromuscular synaptic transmission GO:0007274 2 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
regulation of molecular function GO:0065009 70 0.015
g protein coupled receptor signaling pathway GO:0007186 74 0.015
antimicrobial humoral response GO:0019730 2 0.015
response to nitrogen compound GO:1901698 19 0.015
striated muscle cell differentiation GO:0051146 129 0.014
liver development GO:0001889 96 0.014
lymphocyte proliferation GO:0046651 1 0.014
mesoderm development GO:0007498 88 0.014
gland development GO:0048732 143 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.014
response to nicotine GO:0035094 2 0.014
cellular protein metabolic process GO:0044267 129 0.014
positive regulation of biological process GO:0048518 253 0.014
spemann organizer formation at the embryonic shield GO:0060063 2 0.014
cell killing GO:0001906 2 0.014
rna biosynthetic process GO:0032774 181 0.014
leukocyte proliferation GO:0070661 1 0.014
positive regulation of leukocyte mediated immunity GO:0002705 1 0.014
positive regulation of metabolic process GO:0009893 108 0.014
regulation of signal transduction GO:0009966 225 0.013
startle response GO:0001964 4 0.013
epithelial cell development GO:0002064 42 0.013
anterior posterior pattern specification GO:0009952 152 0.013
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.013
cellular response to starvation GO:0009267 1 0.013
cellular amine metabolic process GO:0044106 2 0.013
ovulation cycle process GO:0022602 2 0.013
embryonic skeletal joint development GO:0072498 3 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
muscle structure development GO:0061061 196 0.013
negative regulation of gene expression GO:0010629 65 0.013
negative regulation of hormone secretion GO:0046888 2 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
response to abiotic stimulus GO:0009628 122 0.013
complement activation GO:0006956 3 0.013
fin morphogenesis GO:0033334 53 0.013
organic substance biosynthetic process GO:1901576 289 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
female sex differentiation GO:0046660 4 0.012
type b pancreatic cell development GO:0003323 4 0.012
medial fin development GO:0033338 16 0.012
appendage development GO:0048736 80 0.012
caudal fin morphogenesis GO:0035143 7 0.012
negative regulation of immune response GO:0050777 2 0.012
lipid storage GO:0019915 1 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
regulation of programmed cell death GO:0043067 101 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
leukocyte mediated cytotoxicity GO:0001909 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
cellular response to external stimulus GO:0071496 2 0.012
positive regulation of transport GO:0051050 2 0.012
cellular response to radiation GO:0071478 4 0.012
cellular component movement GO:0006928 335 0.012
tissue remodeling GO:0048771 4 0.012
regulation of protein transport GO:0051223 3 0.012
cytokinesis GO:0000910 3 0.012
eye morphogenesis GO:0048592 144 0.012
stem cell differentiation GO:0048863 117 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
embryonic heart tube development GO:0035050 133 0.011
cellular response to nutrient levels GO:0031669 2 0.011
spermatid development GO:0007286 2 0.011
oocyte maturation GO:0001556 4 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
multi organism process GO:0051704 134 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regulation of dna replication GO:0006275 3 0.011
somitogenesis GO:0001756 87 0.011
negative regulation of cell death GO:0060548 60 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
regulation of tube size GO:0035150 2 0.011
tube morphogenesis GO:0035239 349 0.011
hormone secretion GO:0046879 2 0.011
somite development GO:0061053 96 0.011
nucleic acid metabolic process GO:0090304 244 0.010
peptide transport GO:0015833 1 0.010
circulatory system process GO:0003013 87 0.010
protein acetylation GO:0006473 2 0.010
positive regulation of signaling GO:0023056 56 0.010
regulation of reproductive process GO:2000241 4 0.010
inner ear development GO:0048839 126 0.010
growth GO:0040007 174 0.010

mhc2dcb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.010