Danio rerio

0 known processes

nfe2l1

nuclear factor, erythroid derived 2,-like 1

nfe2l1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.171
cellular response to light stimulus GO:0071482 4 0.156
cytokinesis GO:0000910 3 0.119
photoperiodism GO:0009648 11 0.069
regulation of multicellular organism growth GO:0040014 4 0.064
biosynthetic process GO:0009058 294 0.062
organic substance biosynthetic process GO:1901576 289 0.058
rhodopsin mediated signaling pathway GO:0016056 1 0.056
mitochondrion organization GO:0007005 4 0.051
cellular response to radiation GO:0071478 4 0.049
phototransduction GO:0007602 2 0.048
regulation of sequestering of calcium ion GO:0051282 4 0.046
phototransduction visible light GO:0007603 2 0.040
neurotransmitter secretion GO:0007269 2 0.040
nitrogen compound metabolic process GO:0006807 319 0.040
negative regulation of sequestering of calcium ion GO:0051283 4 0.040
gene expression GO:0010467 252 0.039
positive regulation of cell division GO:0051781 2 0.038
sequestering of calcium ion GO:0051208 3 0.037
heterocycle metabolic process GO:0046483 290 0.036
locomotor rhythm GO:0045475 3 0.036
multicellular organism growth GO:0035264 4 0.035
response to stress GO:0006950 263 0.035
response to chemical GO:0042221 320 0.035
positive regulation of transport GO:0051050 2 0.034
light absorption GO:0016037 2 0.033
aging GO:0007568 2 0.032
purine nucleoside monophosphate catabolic process GO:0009128 4 0.032
regulation of mrna processing GO:0050684 3 0.031
nuclear transport GO:0051169 4 0.031
regulation of protein complex assembly GO:0043254 3 0.031
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.030
phagocytosis GO:0006909 3 0.030
endocrine process GO:0050886 2 0.030
regulation of dna templated transcription in response to stress GO:0043620 0 0.029
neurotransmitter transport GO:0006836 2 0.028
cytokinetic process GO:0032506 2 0.028
muscle structure development GO:0061061 196 0.028
negative regulation of map kinase activity GO:0043407 2 0.028
phagocytosis engulfment GO:0006911 1 0.028
cellular component assembly involved in morphogenesis GO:0010927 107 0.027
organism emergence from protective structure GO:0071684 4 0.027
chordate embryonic development GO:0043009 271 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.026
muscle cell differentiation GO:0042692 139 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
regulation of nucleic acid templated transcription GO:1903506 213 0.026
muscle cell development GO:0055001 115 0.026
neuron differentiation GO:0030182 353 0.026
signal transduction GO:0007165 455 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
oocyte anterior posterior axis specification GO:0007314 4 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
organelle organization GO:0006996 227 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.025
carbohydrate derivative metabolic process GO:1901135 61 0.025
actin filament based movement GO:0030048 1 0.025
sequestering of metal ion GO:0051238 3 0.025
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
amine metabolic process GO:0009308 2 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
inositol lipid mediated signaling GO:0048017 2 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.024
adult behavior GO:0030534 2 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
cellular response to external stimulus GO:0071496 2 0.024
organelle assembly GO:0070925 110 0.024
regulation of circadian rhythm GO:0042752 4 0.023
cellular response to lipopolysaccharide GO:0071222 3 0.023
protein stabilization GO:0050821 2 0.023
cellular biosynthetic process GO:0044249 286 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.023
rna localization GO:0006403 4 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
mechanosensory behavior GO:0007638 2 0.023
response to drug GO:0042493 3 0.023
muscle fiber development GO:0048747 52 0.022
positive regulation of cell cycle GO:0045787 3 0.022
regulation of organelle assembly GO:1902115 4 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
cell part morphogenesis GO:0032990 246 0.022
cellular component morphogenesis GO:0032989 336 0.022
cytoskeleton organization GO:0007010 96 0.022
embryonic organ development GO:0048568 381 0.021
nucleoside monophosphate catabolic process GO:0009125 4 0.021
negative regulation of cellular process GO:0048523 283 0.021
regulation of metal ion transport GO:0010959 4 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
synaptic transmission cholinergic GO:0007271 4 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
regulation of binding GO:0051098 3 0.020
cellular response to oxygen levels GO:0071453 1 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
maternal determination of anterior posterior axis embryo GO:0008358 4 0.020
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.020
membrane invagination GO:0010324 1 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
sensory perception of smell GO:0007608 2 0.020
axon development GO:0061564 166 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
negative regulation of biological process GO:0048519 304 0.020
rna biosynthetic process GO:0032774 181 0.019
cellular response to nutrient levels GO:0031669 2 0.019
transport GO:0006810 220 0.019
protein localization to plasma membrane GO:0072659 1 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
transcription dna templated GO:0006351 181 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
neuromuscular synaptic transmission GO:0007274 2 0.019
camera type eye development GO:0043010 222 0.019
cellular component movement GO:0006928 335 0.019
protein polymerization GO:0051258 4 0.019
maintenance of location GO:0051235 4 0.019
regulation of muscle contraction GO:0006937 3 0.019
pole plasm assembly GO:0007315 4 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
cellular component biogenesis GO:0044085 178 0.019
fertilization GO:0009566 3 0.019
regulation of cell activation GO:0050865 1 0.018
toll like receptor signaling pathway GO:0002224 4 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
meiotic nuclear division GO:0007126 4 0.018
cell migration GO:0016477 237 0.018
protein metabolic process GO:0019538 183 0.018
establishment of localization GO:0051234 244 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
negative regulation of mapk cascade GO:0043409 4 0.018
positive regulation of blood circulation GO:1903524 2 0.018
organelle fusion GO:0048284 3 0.018
single organism metabolic process GO:0044710 217 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
intracellular mrna localization GO:0008298 1 0.018
regulation of cytokine production GO:0001817 3 0.017
regionalization GO:0003002 274 0.017
light induced release of internally sequestered calcium ion GO:0008377 1 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
regulation of reproductive process GO:2000241 4 0.017
regulation of blood vessel size GO:0050880 2 0.017
axonogenesis GO:0007409 152 0.017
striated muscle cell development GO:0055002 108 0.017
protein import into nucleus GO:0006606 3 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
cell substrate adhesion GO:0031589 4 0.017
lipid storage GO:0019915 1 0.017
atp catabolic process GO:0006200 4 0.017
alternative mrna splicing via spliceosome GO:0000380 1 0.017
negative regulation of catabolic process GO:0009895 3 0.017
regulation of gene expression GO:0010468 265 0.017
cellular response to starvation GO:0009267 1 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
regulation of establishment of protein localization GO:0070201 4 0.016
pyrimidine containing compound metabolic process GO:0072527 3 0.016
protein import GO:0017038 3 0.016
digestive system development GO:0055123 289 0.016
peptide metabolic process GO:0006518 1 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
smooth muscle contraction GO:0006939 2 0.016
rna metabolic process GO:0016070 219 0.016
regulation of developmental process GO:0050793 247 0.016
regulation of glial cell differentiation GO:0045685 4 0.016
multi organism process GO:0051704 134 0.016
macromolecular complex disassembly GO:0032984 1 0.016
muscle tissue development GO:0060537 110 0.016
catechol containing compound metabolic process GO:0009712 2 0.016
xenobiotic metabolic process GO:0006805 4 0.016
cell projection morphogenesis GO:0048858 244 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
regulation of protein targeting GO:1903533 2 0.016
regulation of systemic arterial blood pressure GO:0003073 1 0.016
gtp catabolic process GO:0006184 2 0.016
dopamine metabolic process GO:0042417 2 0.016
nucleic acid metabolic process GO:0090304 244 0.016
b cell activation GO:0042113 2 0.016
oxidative phosphorylation GO:0006119 1 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
cellular amide metabolic process GO:0043603 4 0.015
actin filament polymerization GO:0030041 2 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
protein localization to nucleus GO:0034504 3 0.015
cellular protein catabolic process GO:0044257 4 0.015
positive regulation of cell activation GO:0050867 1 0.015
cellular response to hypoxia GO:0071456 1 0.015
skeletal muscle tissue development GO:0007519 67 0.015
developmental growth GO:0048589 166 0.015
single organism membrane fusion GO:0044801 2 0.015
dna catabolic process GO:0006308 1 0.015
interspecies interaction between organisms GO:0044419 4 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
multi organism cellular process GO:0044764 2 0.015
cytoplasm organization GO:0007028 4 0.015
nuclear import GO:0051170 3 0.015
system process GO:0003008 185 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
response to virus GO:0009615 21 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
somite development GO:0061053 96 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
generation of neurons GO:0048699 385 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
segmentation GO:0035282 97 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
glial cell proliferation GO:0014009 4 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
protein complex disassembly GO:0043241 1 0.015
positive regulation of immune effector process GO:0002699 3 0.014
alcohol biosynthetic process GO:0046165 2 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
skeletal muscle organ development GO:0060538 78 0.014
stem cell proliferation GO:0072089 4 0.014
regulation of protein binding GO:0043393 3 0.014
response to uv GO:0009411 3 0.014
reactive oxygen species biosynthetic process GO:1903409 1 0.014
autophagy GO:0006914 4 0.014
response to hydrogen peroxide GO:0042542 3 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
regulation of cell projection assembly GO:0060491 4 0.014
sphingolipid biosynthetic process GO:0030148 2 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.014
oxidation reduction process GO:0055114 41 0.014
regulation of rna metabolic process GO:0051252 224 0.014
cellular amine metabolic process GO:0044106 2 0.014
female gonad development GO:0008585 4 0.014
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 0 0.014
skeletal system development GO:0001501 181 0.014
cellular component disassembly GO:0022411 1 0.014
regulation of biological quality GO:0065008 263 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
nucleic acid templated transcription GO:0097659 181 0.014
striated muscle tissue development GO:0014706 110 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
detection of visible light GO:0009584 12 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
striated muscle cell differentiation GO:0051146 129 0.014
protein secretion GO:0009306 1 0.013
translational initiation GO:0006413 3 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.013
viral process GO:0016032 1 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
small molecule catabolic process GO:0044282 3 0.013
positive regulation of secretion GO:0051047 1 0.013
regulation of protein polymerization GO:0032271 2 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
positive regulation of biological process GO:0048518 253 0.013
peptidyl serine phosphorylation GO:0018105 1 0.013
golgi vesicle transport GO:0048193 3 0.013
small molecule metabolic process GO:0044281 77 0.013
single organism nuclear import GO:1902593 3 0.013
protein acetylation GO:0006473 2 0.013
regulation of transcription dna templated GO:0006355 213 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
carbohydrate homeostasis GO:0033500 1 0.013
regulation of cell differentiation GO:0045595 142 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
catecholamine metabolic process GO:0006584 2 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
glycolipid metabolic process GO:0006664 8 0.013
embryonic heart tube development GO:0035050 133 0.013
protein targeting to nucleus GO:0044744 3 0.013
skeletal muscle thin filament assembly GO:0030240 4 0.013
sensory organ development GO:0007423 393 0.013
response to organic substance GO:0010033 153 0.013
gtp metabolic process GO:0046039 4 0.013
estrogen metabolic process GO:0008210 2 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
meiotic cell cycle process GO:1903046 3 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
regulation of endocrine process GO:0044060 2 0.013
response to external stimulus GO:0009605 264 0.013
lateral inhibition GO:0046331 1 0.013
neuron development GO:0048666 262 0.013
response to nutrient GO:0007584 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
positive regulation of protein polymerization GO:0032273 2 0.013
cellular localization GO:0051641 97 0.013
ventricular cardiac muscle tissue development GO:0003229 3 0.013
regulation of tube size GO:0035150 2 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
peptide transport GO:0015833 1 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
hatching GO:0035188 4 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regulation of metabolic process GO:0019222 359 0.013
anterior posterior pattern specification GO:0009952 152 0.013
specification of organ identity GO:0010092 2 0.013
regulation of response to stimulus GO:0048583 269 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.012
positive regulation of cytokine production GO:0001819 2 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
response to external biotic stimulus GO:0043207 97 0.012
axon cargo transport GO:0008088 2 0.012
cell matrix adhesion GO:0007160 4 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
regulation of blood pressure GO:0008217 1 0.012
regulation of protein depolymerization GO:1901879 1 0.012
synaptic vesicle localization GO:0097479 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
response to unfolded protein GO:0006986 2 0.012
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
somatic muscle development GO:0007525 4 0.012
cellular lipid catabolic process GO:0044242 3 0.012
regulation of translational initiation GO:0006446 1 0.012
actin filament based process GO:0030029 64 0.012
cellular ketone metabolic process GO:0042180 11 0.012
positive regulation of catabolic process GO:0009896 4 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
protein acylation GO:0043543 3 0.012
response to corticosteroid GO:0031960 1 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
single organism organelle organization GO:1902589 199 0.012
hatching gland development GO:0048785 3 0.012
cell projection organization GO:0030030 284 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
protein complex localization GO:0031503 1 0.012
zymogen activation GO:0031638 3 0.012
regulation of calcium ion transport GO:0051924 2 0.012
exocytosis GO:0006887 1 0.012
stem cell maintenance GO:0019827 4 0.012
double strand break repair GO:0006302 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
myofibril assembly GO:0030239 48 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
regulation of protein catabolic process GO:0042176 1 0.012
response to xenobiotic stimulus GO:0009410 45 0.012
regulation of cell shape GO:0008360 1 0.012
locomotion GO:0040011 313 0.012
negative regulation of kinase activity GO:0033673 4 0.012
pigmentation GO:0043473 85 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
mitochondrial transport GO:0006839 2 0.011
positive regulation of reproductive process GO:2000243 2 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
muscle organ development GO:0007517 101 0.011
glucose homeostasis GO:0042593 1 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
regulation of transporter activity GO:0032409 2 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
dopamine biosynthetic process GO:0042416 2 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
spermatid differentiation GO:0048515 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
organic acid catabolic process GO:0016054 3 0.011
nitric oxide metabolic process GO:0046209 2 0.011
synaptic vesicle transport GO:0048489 1 0.011
peptidyl serine modification GO:0018209 2 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
response to amino acid GO:0043200 2 0.011
neuron projection morphogenesis GO:0048812 161 0.011
voluntary skeletal muscle contraction GO:0003010 4 0.011
blood vessel development GO:0001568 246 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
response to food GO:0032094 1 0.011
entrainment of circadian clock GO:0009649 2 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
lipid catabolic process GO:0016042 4 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
mitochondrion morphogenesis GO:0070584 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
determination of left right symmetry GO:0007368 179 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
extracellular matrix assembly GO:0085029 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
nuclear migration GO:0007097 3 0.010
regulation of gtpase activity GO:0043087 2 0.010
muscle contraction GO:0006936 18 0.010
cellular respiration GO:0045333 3 0.010
hormone secretion GO:0046879 2 0.010
primary amino compound metabolic process GO:1901160 1 0.010
regulation of localization GO:0032879 104 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
head development GO:0060322 303 0.010
b cell mediated immunity GO:0019724 3 0.010
lamellipodium organization GO:0097581 1 0.010
meiotic chromosome segregation GO:0045132 3 0.010
thermosensory behavior GO:0040040 1 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
cellular component assembly GO:0022607 170 0.010
regulation of protein transport GO:0051223 3 0.010
regulation of dendrite development GO:0050773 3 0.010
muscle system process GO:0003012 20 0.010
establishment of blood brain barrier GO:0060856 2 0.010
behavior GO:0007610 74 0.010
absorption of visible light GO:0016038 2 0.010
respiratory electron transport chain GO:0022904 2 0.010

nfe2l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.057
disease of anatomical entity DOID:7 0 0.057
eye and adnexa disease DOID:1492 0 0.057
nervous system disease DOID:863 0 0.057
eye disease DOID:5614 0 0.057
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023
organ system cancer DOID:0050686 0 0.020
retinal disease DOID:5679 0 0.019
cardiovascular system disease DOID:1287 0 0.012