Danio rerio

0 known processes

pdgfab

platelet derived growth factor alpha b

(Aliases: zgc:153249,MGC153249,wu:fc32c12)

pdgfab biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to chemical GO:0042221 320 0.168
Human
cellular amide metabolic process GO:0043603 4 0.119
larval development GO:0002164 2 0.080
aging GO:0007568 2 0.079
digestive system development GO:0055123 289 0.079
Mouse
embryonic organ development GO:0048568 381 0.071
Mouse
localization of cell GO:0051674 244 0.068
Human
signal transduction GO:0007165 455 0.066
Human
regulation of metabolic process GO:0019222 359 0.066
Human Mouse
chordate embryonic development GO:0043009 271 0.065
organic cyclic compound metabolic process GO:1901360 301 0.063
Human
regulation of wound healing GO:0061041 2 0.062
Human
regulation of multicellular organismal process GO:0051239 277 0.060
Human Mouse
digestive tract development GO:0048565 265 0.056
Mouse
glial cell migration GO:0008347 3 0.056
tube morphogenesis GO:0035239 349 0.055
cellular component movement GO:0006928 335 0.055
Human
response to external stimulus GO:0009605 264 0.054
Human
generation of neurons GO:0048699 385 0.054
regulation of biological quality GO:0065008 263 0.052
Human
determination of bilateral symmetry GO:0009855 204 0.052
cell migration GO:0016477 237 0.052
Human
central nervous system development GO:0007417 387 0.050
phagocytosis GO:0006909 3 0.049
sensory perception of chemical stimulus GO:0007606 3 0.049
gland development GO:0048732 143 0.048
Mouse
positive regulation of cell cycle GO:0045787 3 0.046
muscle tissue development GO:0060537 110 0.045
odontogenesis of dentin containing tooth GO:0042475 1 0.044
regulation of erk1 and erk2 cascade GO:0070372 4 0.044
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.044
cellular component biogenesis GO:0044085 178 0.043
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.043
Human
cellular component morphogenesis GO:0032989 336 0.043
regulation of signaling GO:0023051 235 0.041
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.040
Human
cell projection organization GO:0030030 284 0.039
Mouse
cognition GO:0050890 1 0.039
response to drug GO:0042493 3 0.038
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.038
Human
organonitrogen compound metabolic process GO:1901564 74 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.037
neuron differentiation GO:0030182 353 0.037
cellular response to chemical stimulus GO:0070887 157 0.036
biosynthetic process GO:0009058 294 0.036
Human
stem cell proliferation GO:0072089 4 0.036
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.035
glial cell fate specification GO:0021780 4 0.035
multicellular organism growth GO:0035264 4 0.035
positive regulation of transport GO:0051050 2 0.035
stem cell maintenance GO:0019827 4 0.035
regulation of response to stimulus GO:0048583 269 0.035
Human
regulation of cardiac chamber formation GO:1901210 2 0.035
cellular biosynthetic process GO:0044249 286 0.034
Human
nitrogen compound metabolic process GO:0006807 319 0.034
Human
b cell differentiation GO:0030183 1 0.034
regulation of signal transduction GO:0009966 225 0.033
Human
muscle cell migration GO:0014812 4 0.033
Human
establishment of localization GO:0051234 244 0.033
embryonic organ morphogenesis GO:0048562 274 0.033
axon development GO:0061564 166 0.032
skeletal system development GO:0001501 181 0.032
determination of left right symmetry GO:0007368 179 0.032
hemopoiesis GO:0030097 183 0.031
cellular amino acid metabolic process GO:0006520 7 0.031
regulation of cell shape GO:0008360 1 0.031
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.031
Mouse
muscle structure development GO:0061061 196 0.031
negative regulation of kinase activity GO:0033673 4 0.031
regulation of stem cell differentiation GO:2000736 4 0.030
cell surface receptor signaling pathway GO:0007166 325 0.030
Human
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.030
specification of symmetry GO:0009799 204 0.030
protein heterooligomerization GO:0051291 1 0.030
negative chemotaxis GO:0050919 1 0.030
Human
morphogenesis of an epithelium GO:0002009 333 0.029
Mouse
cell projection assembly GO:0030031 64 0.029
Mouse
regulation of mesenchymal cell proliferation GO:0010464 1 0.029
Mouse
regulation of systemic arterial blood pressure GO:0003073 1 0.029
eye development GO:0001654 277 0.029
negative regulation of cellular process GO:0048523 283 0.029
Human
aromatic compound biosynthetic process GO:0019438 217 0.029
regulation of blood pressure GO:0008217 1 0.029
detection of chemical stimulus GO:0009593 4 0.028
regulation of blood vessel size GO:0050880 2 0.028
regulation of cell communication GO:0010646 232 0.028
Human
regulation of multicellular organism growth GO:0040014 4 0.028
cell morphogenesis GO:0000902 289 0.028
b cell activation GO:0042113 2 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
single organism transport GO:0044765 206 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
positive regulation of cytoskeleton organization GO:0051495 3 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
peptide metabolic process GO:0006518 1 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
negative regulation of stem cell differentiation GO:2000737 2 0.027
zymogen activation GO:0031638 3 0.027
cranial ganglion development GO:0061550 3 0.027
tissue remodeling GO:0048771 4 0.027
positive regulation of catabolic process GO:0009896 4 0.026
regulation of primary metabolic process GO:0080090 311 0.026
Human Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.026
positive regulation of cell activation GO:0050867 1 0.026
developmental programmed cell death GO:0010623 4 0.026
meiotic nuclear division GO:0007126 4 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
phosphatidylinositol biosynthetic process GO:0006661 1 0.026
Human
maintenance of location GO:0051235 4 0.025
heart development GO:0007507 313 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
Human
response to external biotic stimulus GO:0043207 97 0.025
oligodendrocyte cell fate specification GO:0021778 4 0.025
response to other organism GO:0051707 97 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
Human
positive regulation of protein polymerization GO:0032273 2 0.025
muscle cell differentiation GO:0042692 139 0.025
regulation of cytokine production GO:0001817 3 0.025
transport GO:0006810 220 0.025
endocrine process GO:0050886 2 0.025
positive regulation of cellular process GO:0048522 201 0.025
Human Mouse
regulation of cell activation GO:0050865 1 0.025
Human
system process GO:0003008 185 0.025
Zebrafish
protein localization to nucleus GO:0034504 3 0.025
cell motility GO:0048870 244 0.025
Human
regulation of macromolecule metabolic process GO:0060255 317 0.025
Human Mouse
cellular ketone metabolic process GO:0042180 11 0.024
single organism localization GO:1902578 225 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
immune system development GO:0002520 191 0.024
response to organic substance GO:0010033 153 0.024
regulation of stem cell proliferation GO:0072091 2 0.024
Mouse
axonogenesis GO:0007409 152 0.024
erk1 and erk2 cascade GO:0070371 4 0.024
Human
immune system process GO:0002376 241 0.024
adult behavior GO:0030534 2 0.023
lateral inhibition GO:0046331 1 0.023
protein polymerization GO:0051258 4 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
regulation of transcription dna templated GO:0006355 213 0.023
taxis GO:0042330 109 0.023
Human
single organism organelle organization GO:1902589 199 0.023
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.023
regulation of tube size GO:0035150 2 0.023
glycerophospholipid biosynthetic process GO:0046474 1 0.023
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.023
Human
determination of heart left right asymmetry GO:0061371 117 0.023
positive regulation of cytokine production GO:0001819 2 0.023
epidermal cell fate specification GO:0009957 4 0.022
heterocycle metabolic process GO:0046483 290 0.022
Human
negative regulation of chromosome organization GO:2001251 1 0.022
neuron development GO:0048666 262 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
Human
negative regulation of biological process GO:0048519 304 0.022
Human
regionalization GO:0003002 274 0.022
digestive tract morphogenesis GO:0048546 231 0.022
positive regulation of protein complex assembly GO:0031334 2 0.022
sensory organ morphogenesis GO:0090596 200 0.022
developmental growth GO:0048589 166 0.022
regulation of anatomical structure morphogenesis GO:0022603 130 0.022
Mouse
regulation of circadian rhythm GO:0042752 4 0.022
cellular amine metabolic process GO:0044106 2 0.022
transcription dna templated GO:0006351 181 0.022
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.022
regulation of organ growth GO:0046620 3 0.022
cellular modified amino acid metabolic process GO:0006575 3 0.022
striated muscle cell differentiation GO:0051146 129 0.021
myelin assembly GO:0032288 1 0.021
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
gene expression GO:0010467 252 0.021
regulation of synapse organization GO:0050807 3 0.021
regulation of synapse assembly GO:0051963 3 0.021
oocyte maturation GO:0001556 4 0.021
mononuclear cell proliferation GO:0032943 1 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
Human
ribosome assembly GO:0042255 1 0.021
leukocyte proliferation GO:0070661 1 0.020
regulation of dna replication GO:0006275 3 0.020
Human
organic substance biosynthetic process GO:1901576 289 0.020
Human
regulation of developmental process GO:0050793 247 0.020
Human Mouse
regulation of filopodium assembly GO:0051489 2 0.020
rna metabolic process GO:0016070 219 0.020
neuron projection morphogenesis GO:0048812 161 0.020
cardiac chamber formation GO:0003207 4 0.020
regulation of hormone secretion GO:0046883 2 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
Human Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.019
Human
apoptotic process involved in development GO:1902742 2 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
muscle organ development GO:0007517 101 0.019
response to uv GO:0009411 3 0.019
nucleic acid metabolic process GO:0090304 244 0.019
Human
regulation of rna metabolic process GO:0051252 224 0.019
hatching gland development GO:0048785 3 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
Human Mouse
response to corticosteroid GO:0031960 1 0.019
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.019
Human
sleep GO:0030431 1 0.019
cellular response to radiation GO:0071478 4 0.019
single organism metabolic process GO:0044710 217 0.019
Human
renal system development GO:0072001 94 0.019
Human
regulation of myotube differentiation GO:0010830 2 0.019
regulation of cell projection assembly GO:0060491 4 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
phagocytosis engulfment GO:0006911 1 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
cell projection morphogenesis GO:0048858 244 0.018
striated muscle tissue development GO:0014706 110 0.018
positive regulation of biological process GO:0048518 253 0.018
Human Mouse
positive regulation of notch signaling pathway GO:0045747 3 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
pathway restricted smad protein phosphorylation GO:0060389 1 0.018
skeletal system morphogenesis GO:0048705 102 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
Human Mouse
membrane invagination GO:0010324 1 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
trabecula morphogenesis GO:0061383 2 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.018
negative regulation of histone modification GO:0031057 1 0.018
camera type eye development GO:0043010 222 0.018
regulation of cardiac chamber morphogenesis GO:1901219 2 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.018
negative regulation of leukocyte differentiation GO:1902106 1 0.018
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.018
response to abiotic stimulus GO:0009628 122 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
Human
gtp metabolic process GO:0046039 4 0.018
actin polymerization or depolymerization GO:0008154 2 0.017
neurological system process GO:0050877 62 0.017
mitochondrion organization GO:0007005 4 0.017
spermatid development GO:0007286 2 0.017
urogenital system development GO:0001655 97 0.017
Human
lymphocyte proliferation GO:0046651 1 0.017
negative regulation of mapk cascade GO:0043409 4 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
response to oxygen containing compound GO:1901700 55 0.017
embryonic skeletal system morphogenesis GO:0048704 93 0.017
response to biotic stimulus GO:0009607 97 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of protein complex assembly GO:0043254 3 0.017
protein metabolic process GO:0019538 183 0.017
Human Mouse
endocrine hormone secretion GO:0060986 2 0.017
kidney development GO:0001822 92 0.017
Human
mesenchyme development GO:0060485 127 0.017
lipid storage GO:0019915 1 0.017
meiosis i GO:0007127 1 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
Human
macromolecule modification GO:0043412 111 0.017
Human Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.017
response to carbohydrate GO:0009743 3 0.017
response to glucose GO:0009749 3 0.017
cell death GO:0008219 121 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
epithelial tube morphogenesis GO:0060562 148 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
antimicrobial humoral response GO:0019730 2 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
cellular response to nutrient levels GO:0031669 2 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
cardiac chamber development GO:0003205 19 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
positive regulation of secretion GO:0051047 1 0.016
neuron projection development GO:0031175 180 0.016
locomotion GO:0040011 313 0.016
Human
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
Mouse
gas transport GO:0015669 3 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
organic acid metabolic process GO:0006082 31 0.016
response to organic cyclic compound GO:0014070 51 0.016
positive regulation of epithelial cell proliferation GO:0050679 1 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
pharyngeal muscle development GO:0043282 4 0.016
sensory organ development GO:0007423 393 0.016
autophagy GO:0006914 4 0.016
dna templated transcription elongation GO:0006354 3 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
brain development GO:0007420 293 0.016
post embryonic morphogenesis GO:0009886 4 0.016
negative regulation of map kinase activity GO:0043407 2 0.016
negative regulation of cytokine production GO:0001818 1 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
response to monosaccharide GO:0034284 3 0.015
regulation of response to extracellular stimulus GO:0032104 1 0.015
regulation of dendrite development GO:0050773 3 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
positive regulation of myeloid cell differentiation GO:0045639 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
positive regulation of protein kinase b signaling GO:0051897 1 0.015
Human
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
neurotransmitter transport GO:0006836 2 0.015
mesenchymal cell proliferation GO:0010463 1 0.015
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
regulation of protein polymerization GO:0032271 2 0.015
regulation of translational initiation GO:0006446 1 0.015
oxoacid metabolic process GO:0043436 31 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
germ line stem cell maintenance GO:0030718 2 0.015
cell part morphogenesis GO:0032990 246 0.015
regulation of binding GO:0051098 3 0.015
protein localization to plasma membrane GO:0072659 1 0.015
cellular component assembly GO:0022607 170 0.015
Mouse
meiotic chromosome segregation GO:0045132 3 0.015
protein secretion GO:0009306 1 0.015
gtp catabolic process GO:0006184 2 0.015
negative regulation of chemotaxis GO:0050922 4 0.015
response to hexose GO:0009746 3 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
small molecule metabolic process GO:0044281 77 0.015
regulation of muscle contraction GO:0006937 3 0.015
regulation of axonogenesis GO:0050770 32 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
circulatory system process GO:0003013 87 0.015
Zebrafish
cell proliferation GO:0008283 80 0.015
Human Mouse
organelle organization GO:0006996 227 0.015
Mouse
cellular protein modification process GO:0006464 100 0.015
Human Mouse
cellular response to starvation GO:0009267 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
nucleic acid templated transcription GO:0097659 181 0.015
blood circulation GO:0008015 87 0.015
Zebrafish
apoptotic process involved in morphogenesis GO:0060561 2 0.015
positive regulation of signaling GO:0023056 56 0.015
Human
regulation of biosynthetic process GO:0009889 250 0.014
Human
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
Human
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.014
neural tube development GO:0021915 62 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
Mouse
cilium assembly GO:0042384 58 0.014
heart looping GO:0001947 94 0.014
head development GO:0060322 303 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
Human
regulation of dna templated transcription elongation GO:0032784 3 0.014
olfactory lobe development GO:0021988 4 0.014
axon ensheathment in central nervous system GO:0032291 2 0.014
positive regulation of immune effector process GO:0002699 3 0.014
cellular response to oxygen levels GO:0071453 1 0.014
protein import into nucleus GO:0006606 3 0.014
positive regulation of muscle organ development GO:0048636 1 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
regulation of epithelial to mesenchymal transition GO:0010717 3 0.014
positive regulation of leukocyte differentiation GO:1902107 1 0.014
synaptic vesicle recycling GO:0036465 1 0.014
post embryonic organ development GO:0048569 4 0.014
circadian sleep wake cycle process GO:0022410 2 0.014
regulation of nervous system development GO:0051960 90 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
Human Zebrafish Mouse
floor plate development GO:0033504 15 0.014
actin filament polymerization GO:0030041 2 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
regulation of protein transport GO:0051223 3 0.014
neuroblast differentiation GO:0014016 1 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
negative regulation of protein complex assembly GO:0031333 1 0.014
single organism nuclear import GO:1902593 3 0.014
glycerolipid biosynthetic process GO:0045017 1 0.014
Human
protein dephosphorylation GO:0006470 3 0.014
catechol containing compound metabolic process GO:0009712 2 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
epithelial cell morphogenesis GO:0003382 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
female sex differentiation GO:0046660 4 0.013
macroautophagy GO:0016236 1 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
Human Zebrafish Mouse
protein targeting to nucleus GO:0044744 3 0.013
forebrain development GO:0030900 96 0.013
activation of mapk activity GO:0000187 3 0.013
hormone transport GO:0009914 2 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
regulation of localization GO:0032879 104 0.013
Human
lymphangiogenesis GO:0001946 25 0.013
Zebrafish
detection of chemical stimulus involved in sensory perception GO:0050907 3 0.013
response to glucocorticoid GO:0051384 1 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
glial cell proliferation GO:0014009 4 0.013
regulation of photoreceptor cell differentiation GO:0046532 2 0.013
cell cycle arrest GO:0007050 1 0.013
protein homooligomerization GO:0051260 3 0.013
regulation of protein catabolic process GO:0042176 1 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
membrane raft organization GO:0031579 1 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
growth GO:0040007 174 0.013
rna biosynthetic process GO:0032774 181 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
positive regulation of dna templated transcription elongation GO:0032786 1 0.013
somatic stem cell maintenance GO:0035019 1 0.013
water homeostasis GO:0030104 4 0.013
cellular response to retinoic acid GO:0071300 1 0.013
protein acetylation GO:0006473 2 0.013
hormone secretion GO:0046879 2 0.013
regulation of cell differentiation GO:0045595 142 0.013
regulation of gtpase activity GO:0043087 2 0.013
cardiac atrium development GO:0003230 4 0.013
reflex GO:0060004 2 0.013
regulation of jun kinase activity GO:0043506 3 0.013
blood vessel development GO:0001568 246 0.013
Zebrafish Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
cartilage development GO:0051216 96 0.013
central nervous system myelin formation GO:0032289 1 0.012
er nucleus signaling pathway GO:0006984 2 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
Human
response to bacterium GO:0009617 58 0.012
nitric oxide metabolic process GO:0046209 2 0.012
regulation of protein targeting GO:1903533 2 0.012
carbohydrate homeostasis GO:0033500 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
central nervous system neuron differentiation GO:0021953 74 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
glucose homeostasis GO:0042593 1 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
tube closure GO:0060606 1 0.012
neuron projection guidance GO:0097485 86 0.012
somatic muscle development GO:0007525 4 0.012
cell aging GO:0007569 2 0.012
lens fiber cell morphogenesis GO:0070309 3 0.012
phosphorylation GO:0016310 69 0.012
Human Zebrafish Mouse
negative regulation of nucleic acid templated transcription GO:1903507 45 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
olfactory bulb development GO:0021772 4 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
Human
transcription from rna polymerase ii promoter GO:0006366 80 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
meiotic cell cycle process GO:1903046 3 0.012
embryonic skeletal system development GO:0048706 97 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
embryonic digestive tract development GO:0048566 4 0.012
lymph vessel development GO:0001945 27 0.012
Zebrafish
cellular component disassembly GO:0022411 1 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
cell cell recognition GO:0009988 1 0.012
positive regulation of metabolic process GO:0009893 108 0.012
Human
transmission of nerve impulse GO:0019226 19 0.012
negative regulation of myeloid cell differentiation GO:0045638 1 0.012
neuronal action potential GO:0019228 18 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
midbrain development GO:0030901 28 0.012
myeloid leukocyte differentiation GO:0002573 15 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
positive regulation of translation GO:0045727 1 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.011
insulin like growth factor receptor signaling pathway GO:0048009 4 0.011
immune effector process GO:0002252 23 0.011
actin filament based movement GO:0030048 1 0.011
chromatin modification GO:0016568 21 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
cellular response to stress GO:0033554 62 0.011
compound eye development GO:0048749 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of mrna processing GO:0050684 3 0.011
cellular protein metabolic process GO:0044267 129 0.011
Human Mouse
smooth muscle contraction GO:0006939 2 0.011
myeloid cell differentiation GO:0030099 86 0.011
response to hormone GO:0009725 48 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
lateral line ganglion development GO:0048890 2 0.011
nuclear import GO:0051170 3 0.011
organophosphate biosynthetic process GO:0090407 23 0.011
Human
cellular response to endogenous stimulus GO:0071495 68 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of biomineral tissue development GO:0070167 2 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
regulation of oocyte development GO:0060281 3 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
ventral spinal cord interneuron differentiation GO:0021514 12 0.011

pdgfab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
cardiovascular system disease DOID:1287 0 0.016
musculoskeletal system disease DOID:17 0 0.015
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
myopathy DOID:423 0 0.013
organ system cancer DOID:0050686 0 0.013