|
|
positive regulation of map kinase activity
|
GO:0043406 |
3 |
0.850
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
2 |
0.817
|
Human |
|
|
hemostasis
|
GO:0007599 |
13 |
0.813
|
Human |
|
|
signal transduction
|
GO:0007165 |
455 |
0.812
|
Human |
|
|
regulation of signaling
|
GO:0023051 |
235 |
0.802
|
Human |
|
|
skin development
|
GO:0043588 |
54 |
0.777
|
Mouse |
|
|
regulation of biological quality
|
GO:0065008 |
263 |
0.659
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
381 |
0.624
|
Mouse Fly |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
4 |
0.614
|
Human |
|
|
positive regulation of cellular process
|
GO:0048522 |
201 |
0.584
|
Human Mouse |
|
|
system process
|
GO:0003008 |
185 |
0.583
|
Zebrafish |
|
|
regulation of wound healing
|
GO:0061041 |
2 |
0.575
|
Human |
|
|
cellular aromatic compound metabolic process
|
GO:0006725 |
295 |
0.571
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
4 |
0.545
|
Human |
|
|
response to organic substance
|
GO:0010033 |
153 |
0.534
|
|
|
|
heterocycle metabolic process
|
GO:0046483 |
290 |
0.517
|
Human |
|
|
cell surface receptor signaling pathway
|
GO:0007166 |
325 |
0.508
|
Human |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
191 |
0.508
|
Fly |
|
|
coagulation
|
GO:0050817 |
13 |
0.507
|
Human |
|
|
response to chemical
|
GO:0042221 |
320 |
0.495
|
Human |
|
|
digestive tract development
|
GO:0048565 |
265 |
0.495
|
Mouse Fly |
|
|
cellular component movement
|
GO:0006928 |
335 |
0.491
|
Human Fly |
|
|
determination of bilateral symmetry
|
GO:0009855 |
204 |
0.490
|
|
|
|
nitrogen compound metabolic process
|
GO:0006807 |
319 |
0.439
|
Human |
|
|
regulation of developmental process
|
GO:0050793 |
247 |
0.438
|
Human Mouse |
|
|
cellular macromolecule biosynthetic process
|
GO:0034645 |
224 |
0.436
|
Human |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
69 |
0.402
|
Human |
|
|
regulation of multicellular organismal process
|
GO:0051239 |
277 |
0.384
|
Human Mouse |
|
|
epithelial cell development
|
GO:0002064 |
42 |
0.374
|
Fly |
|
|
cell fate commitment
|
GO:0045165 |
99 |
0.366
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
225 |
0.361
|
Human |
|
|
regulation of stem cell proliferation
|
GO:0072091 |
2 |
0.358
|
Mouse |
|
|
nucleobase containing compound metabolic process
|
GO:0006139 |
274 |
0.357
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
148 |
0.355
|
Fly |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
157 |
0.354
|
|
|
|
kidney development
|
GO:0001822 |
92 |
0.352
|
Human |
|
|
stem cell proliferation
|
GO:0072089 |
4 |
0.337
|
Mouse |
|
|
positive regulation of cellular metabolic process
|
GO:0031325 |
94 |
0.334
|
Human |
|
|
response to glucose
|
GO:0009749 |
3 |
0.327
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
4 |
0.325
|
|
|
|
regulation of primary metabolic process
|
GO:0080090 |
311 |
0.320
|
Human Mouse |
|
|
positive regulation of metabolic process
|
GO:0009893 |
108 |
0.319
|
Human |
|
|
larval development
|
GO:0002164 |
2 |
0.309
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
1 |
0.298
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
3 |
0.296
|
|
|
|
organic cyclic compound metabolic process
|
GO:1901360 |
301 |
0.292
|
Human |
|
|
cellular nitrogen compound biosynthetic process
|
GO:0044271 |
218 |
0.279
|
|
|
|
cellular macromolecule metabolic process
|
GO:0044260 |
391 |
0.272
|
Human Mouse |
|
|
blood circulation
|
GO:0008015 |
87 |
0.267
|
Zebrafish |
|
|
cell projection morphogenesis
|
GO:0048858 |
244 |
0.265
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
17 |
0.260
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
69 |
0.259
|
Human |
|
|
regulation of cell communication
|
GO:0010646 |
232 |
0.255
|
Human |
|
|
determination of heart left right asymmetry
|
GO:0061371 |
117 |
0.253
|
|
|
|
regulation of metabolic process
|
GO:0019222 |
359 |
0.246
|
Human Mouse |
|
|
regulation of macromolecule metabolic process
|
GO:0060255 |
317 |
0.236
|
Human Mouse |
|
|
negative regulation of cellular process
|
GO:0048523 |
283 |
0.230
|
Human Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
3 |
0.230
|
|
|
|
regulation of cellular metabolic process
|
GO:0031323 |
320 |
0.219
|
Human Mouse |
|
|
response to external stimulus
|
GO:0009605 |
264 |
0.218
|
Human |
|
|
regulation of transcription dna templated
|
GO:0006355 |
213 |
0.216
|
|
|
|
cell projection organization
|
GO:0030030 |
284 |
0.208
|
Mouse Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
106 |
0.206
|
Human |
|
|
cellular nitrogen compound metabolic process
|
GO:0034641 |
290 |
0.206
|
Human |
|
|
regulation of cell activation
|
GO:0050865 |
1 |
0.200
|
Human |
|
|
regulation of response to stimulus
|
GO:0048583 |
269 |
0.198
|
Human Fly |
|
|
cell activation
|
GO:0001775 |
16 |
0.193
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
349 |
0.191
|
Fly |
|
|
specification of symmetry
|
GO:0009799 |
204 |
0.189
|
|
|
|
response to wounding
|
GO:0009611 |
116 |
0.186
|
Human |
|
|
negative regulation of biological process
|
GO:0048519 |
304 |
0.184
|
Human Fly |
|
|
wound healing
|
GO:0042060 |
90 |
0.183
|
Human |
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
1 |
0.181
|
|
|
|
circulatory system process
|
GO:0003013 |
87 |
0.180
|
Zebrafish |
|
|
digestive system development
|
GO:0055123 |
289 |
0.172
|
Mouse Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
13 |
0.171
|
Human |
|
|
sexual reproduction
|
GO:0019953 |
36 |
0.169
|
Fly |
|
|
chordate embryonic development
|
GO:0043009 |
271 |
0.168
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
52 |
0.167
|
Human Mouse |
|
|
epidermal cell fate specification
|
GO:0009957 |
4 |
0.167
|
|
|
|
macromolecule modification
|
GO:0043412 |
111 |
0.166
|
Human Mouse |
|
|
lymphangiogenesis
|
GO:0001946 |
25 |
0.165
|
Zebrafish |
|
|
protein dephosphorylation
|
GO:0006470 |
3 |
0.164
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
68 |
0.162
|
Human |
|
|
organic substance biosynthetic process
|
GO:1901576 |
289 |
0.161
|
Human |
|
|
regulation of cellular macromolecule biosynthetic process
|
GO:2000112 |
222 |
0.161
|
Human |
|
|
positive regulation of signal transduction
|
GO:0009967 |
56 |
0.160
|
Human |
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
68 |
0.156
|
Human |
|
|
camera type eye development
|
GO:0043010 |
222 |
0.152
|
|
|
|
neuron differentiation
|
GO:0030182 |
353 |
0.151
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
274 |
0.150
|
|
|
|
gland development
|
GO:0048732 |
143 |
0.150
|
Mouse Fly |
|
|
response to carbohydrate
|
GO:0009743 |
3 |
0.150
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
105 |
0.148
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
15 |
0.147
|
|
|
|
immune system development
|
GO:0002520 |
191 |
0.147
|
Fly |
|
|
muscle fiber development
|
GO:0048747 |
52 |
0.146
|
|
|
|
cellular biosynthetic process
|
GO:0044249 |
286 |
0.146
|
Human |
|
|
single organism organelle organization
|
GO:1902589 |
199 |
0.145
|
Mouse |
|
|
heterocycle biosynthetic process
|
GO:0018130 |
215 |
0.143
|
|
|
|
regionalization
|
GO:0003002 |
274 |
0.140
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
1 |
0.140
|
Human |
|
|
muscle cell migration
|
GO:0014812 |
4 |
0.140
|
Human |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
93 |
0.139
|
|
|
|
biosynthetic process
|
GO:0009058 |
294 |
0.137
|
Human |
|
|
otic vesicle morphogenesis
|
GO:0071600 |
34 |
0.136
|
|
|
|
positive regulation of transport
|
GO:0051050 |
2 |
0.134
|
|
|
|
blood vessel development
|
GO:0001568 |
246 |
0.132
|
Zebrafish Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
139 |
0.128
|
|
|
|
multi organism process
|
GO:0051704 |
134 |
0.125
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
336 |
0.125
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
179 |
0.123
|
|
|
|
phosphate containing compound metabolic process
|
GO:0006796 |
108 |
0.122
|
Human Zebrafish Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
122 |
0.121
|
Fly |
|
|
urogenital system development
|
GO:0001655 |
97 |
0.121
|
Human Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
4 |
0.118
|
|
|
|
endodermal cell fate determination
|
GO:0007493 |
2 |
0.118
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
2 |
0.116
|
|
|
|
eye development
|
GO:0001654 |
277 |
0.114
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
68 |
0.112
|
|
|
|
rna metabolic process
|
GO:0016070 |
219 |
0.112
|
|
|
|
response to monosaccharide
|
GO:0034284 |
3 |
0.111
|
|
|
|
phosphorus metabolic process
|
GO:0006793 |
109 |
0.111
|
Human Zebrafish Mouse |
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
1 |
0.111
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
53 |
0.110
|
Zebrafish |
|
|
organic cyclic compound biosynthetic process
|
GO:1901362 |
223 |
0.107
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
64 |
0.107
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
129 |
0.105
|
|
|
|
neural tube development
|
GO:0021915 |
62 |
0.104
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
4 |
0.104
|
|
|
|
protein modification process
|
GO:0036211 |
100 |
0.104
|
Human Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
216 |
0.102
|
Zebrafish Mouse |
|
|
gamete generation
|
GO:0007276 |
33 |
0.102
|
Fly |
|
|
response to lipid
|
GO:0033993 |
60 |
0.101
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
146 |
0.101
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
161 |
0.100
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.100
|
|
|
|
hemopoiesis
|
GO:0030097 |
183 |
0.097
|
Fly |
|
|
pronephros development
|
GO:0048793 |
69 |
0.096
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
16 |
0.094
|
Mouse |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
43 |
0.094
|
Human Mouse |
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
52 |
0.093
|
Human |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
1 |
0.093
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
3 |
0.093
|
|
|
|
skeletal system development
|
GO:0001501 |
181 |
0.091
|
|
|
|
multicellular organism growth
|
GO:0035264 |
4 |
0.089
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
3 |
0.088
|
|
|
|
nucleic acid metabolic process
|
GO:0090304 |
244 |
0.086
|
Human |
|
|
oxoacid metabolic process
|
GO:0043436 |
31 |
0.085
|
|
|
|
axonogenesis
|
GO:0007409 |
152 |
0.084
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
90 |
0.080
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
69 |
0.080
|
Human |
|
|
angiogenesis
|
GO:0001525 |
158 |
0.080
|
Zebrafish Mouse |
|
|
immune system process
|
GO:0002376 |
241 |
0.080
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
0 |
0.080
|
|
|
|
floor plate development
|
GO:0033504 |
15 |
0.080
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
37 |
0.079
|
|
|
|
cell cycle process
|
GO:0022402 |
53 |
0.079
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
7 |
0.079
|
|
|
|
generation of neurons
|
GO:0048699 |
385 |
0.078
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
1 |
0.078
|
Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
246 |
0.078
|
|
|
|
muscle structure development
|
GO:0061061 |
196 |
0.077
|
|
|
|
regulation of dna replication
|
GO:0006275 |
3 |
0.077
|
Human |
|
|
lymph vessel morphogenesis
|
GO:0036303 |
25 |
0.077
|
Zebrafish |
|
|
regulation of cellular component organization
|
GO:0051128 |
86 |
0.076
|
|
|
|
positive regulation of biological process
|
GO:0048518 |
253 |
0.075
|
Human Mouse |
|
|
central nervous system myelin formation
|
GO:0032289 |
1 |
0.074
|
|
|
|
protein import into nucleus
|
GO:0006606 |
3 |
0.074
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
24 |
0.073
|
|
|
|
oligodendrocyte cell fate specification
|
GO:0021778 |
4 |
0.073
|
|
|
|
gene expression
|
GO:0010467 |
252 |
0.073
|
|
|
|
central nervous system development
|
GO:0007417 |
387 |
0.072
|
|
|
|
mitochondrion organization
|
GO:0007005 |
4 |
0.072
|
|
|
|
locomotion
|
GO:0040011 |
313 |
0.071
|
Human Fly |
|
|
spinal cord oligodendrocyte cell fate specification
|
GO:0021530 |
2 |
0.071
|
|
|
|
glial cell fate specification
|
GO:0021780 |
4 |
0.070
|
|
|
|
transcription dna templated
|
GO:0006351 |
181 |
0.070
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
25 |
0.070
|
|
|
|
chemotaxis
|
GO:0006935 |
104 |
0.069
|
Human |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
80 |
0.069
|
|
|
|
endothelium development
|
GO:0003158 |
25 |
0.069
|
|
|
|
epidermis development
|
GO:0008544 |
48 |
0.068
|
Mouse |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
80 |
0.068
|
Human |
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
79 |
0.068
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
55 |
0.067
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
1 |
0.067
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
18 |
0.066
|
|
|
|
cell fate specification
|
GO:0001708 |
68 |
0.066
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
52 |
0.065
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
18 |
0.064
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
4 |
0.064
|
|
|
|
odontogenesis
|
GO:0042476 |
9 |
0.064
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
2 |
0.063
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
15 |
0.063
|
Human |
|
|
response to hormone
|
GO:0009725 |
48 |
0.062
|
|
|
|
rna biosynthetic process
|
GO:0032774 |
181 |
0.062
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
1 |
0.062
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
289 |
0.062
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
200 |
0.062
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
31 |
0.061
|
|
|
|
single organism transport
|
GO:0044765 |
206 |
0.061
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
2 |
0.060
|
|
|
|
nucleic acid templated transcription
|
GO:0097659 |
181 |
0.060
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
1 |
0.059
|
|
|
|
apoptotic process
|
GO:0006915 |
116 |
0.059
|
|
|
|
single organism metabolic process
|
GO:0044710 |
217 |
0.058
|
Human |
|
|
response to hexose
|
GO:0009746 |
3 |
0.058
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
15 |
0.057
|
Human Mouse |
|
|
hatching gland development
|
GO:0048785 |
3 |
0.057
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
333 |
0.057
|
Mouse Fly |
|
|
cell proliferation
|
GO:0008283 |
80 |
0.056
|
Human Mouse |
|
|
response to nutrient
|
GO:0007584 |
3 |
0.056
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
72 |
0.055
|
|
|
|
macromolecule biosynthetic process
|
GO:0009059 |
227 |
0.055
|
Human |
|
|
regulation of gene expression
|
GO:0010468 |
265 |
0.055
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
1 |
0.055
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
224 |
0.055
|
|
|
|
neural crest cell development
|
GO:0014032 |
62 |
0.054
|
|
|
|
lymph vessel development
|
GO:0001945 |
27 |
0.054
|
Zebrafish |
|
|
protein targeting to nucleus
|
GO:0044744 |
3 |
0.054
|
|
|
|
neuron development
|
GO:0048666 |
262 |
0.054
|
|
|
|
regulation of cellular biosynthetic process
|
GO:0031326 |
245 |
0.054
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
52 |
0.054
|
|
|
|
cartilage development
|
GO:0051216 |
96 |
0.054
|
|
|
|
cell migration
|
GO:0016477 |
237 |
0.053
|
Human Fly |
|
|
neuron projection guidance
|
GO:0097485 |
86 |
0.053
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
28 |
0.053
|
Fly |
|
|
response to virus
|
GO:0009615 |
21 |
0.053
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
3 |
0.053
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
16 |
0.052
|
Human |
|
|
regulation of nucleobase containing compound metabolic process
|
GO:0019219 |
250 |
0.052
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
3 |
0.052
|
|
|
|
synaptic transmission
|
GO:0007268 |
35 |
0.052
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
1 |
0.051
|
Mouse |
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
29 |
0.051
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
77 |
0.051
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
102 |
0.051
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
78 |
0.051
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
116 |
0.050
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
30 |
0.050
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
1 |
0.049
|
Mouse |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
130 |
0.049
|
Mouse |
|
|
embryonic skeletal system development
|
GO:0048706 |
97 |
0.049
|
|
|
|
regulation of protein transport
|
GO:0051223 |
3 |
0.049
|
|
|
|
endocrine system development
|
GO:0035270 |
65 |
0.049
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
22 |
0.049
|
|
|
|
cranial ganglion development
|
GO:0061550 |
3 |
0.048
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
1 |
0.048
|
Human |
|
|
axon development
|
GO:0061564 |
166 |
0.048
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
23 |
0.047
|
|
|
|
neuron projection development
|
GO:0031175 |
180 |
0.047
|
|
|
|
regulation of tube size
|
GO:0035150 |
2 |
0.047
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
65 |
0.047
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
2 |
0.046
|
|
|
|
brain development
|
GO:0007420 |
293 |
0.046
|
|
|
|
regeneration
|
GO:0031099 |
91 |
0.046
|
|
|
|
regulation of biosynthetic process
|
GO:0009889 |
250 |
0.046
|
Human |
|
|
endodermal cell differentiation
|
GO:0035987 |
19 |
0.046
|
|
|
|
vasculature development
|
GO:0001944 |
278 |
0.045
|
Zebrafish Mouse |
|
|
skeletal muscle tissue development
|
GO:0007519 |
67 |
0.045
|
|
|
|
regulation of macromolecule biosynthetic process
|
GO:0010556 |
225 |
0.045
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
29 |
0.045
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
1 |
0.045
|
|
|
|
eye morphogenesis
|
GO:0048592 |
144 |
0.044
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
1 |
0.044
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
56 |
0.044
|
Human |
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
2 |
0.043
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
2 |
0.043
|
|
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
213 |
0.043
|
|
|
|
developmental growth
|
GO:0048589 |
166 |
0.043
|
|
|
|
protein import
|
GO:0017038 |
3 |
0.043
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
3 |
0.042
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
83 |
0.042
|
|
|
|
muscle organ development
|
GO:0007517 |
101 |
0.042
|
|
|
|
sensory organ development
|
GO:0007423 |
393 |
0.042
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
114 |
0.041
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
2 |
0.041
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
2 |
0.041
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
55 |
0.041
|
|
|
|
regulation of organ growth
|
GO:0046620 |
3 |
0.041
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
77 |
0.040
|
Human |
|
|
lymphatic endothelial cell differentiation
|
GO:0060836 |
1 |
0.040
|
|
|
|
lateral line ganglion development
|
GO:0048890 |
2 |
0.040
|
|
|
|
regulation of cardiac chamber formation
|
GO:1901210 |
2 |
0.040
|
|
|
|
b cell activation
|
GO:0042113 |
2 |
0.040
|
|
|
|
mesenchyme development
|
GO:0060485 |
127 |
0.039
|
|
|
|
tissue regeneration
|
GO:0042246 |
74 |
0.039
|
|
|
|
myelin assembly
|
GO:0032288 |
1 |
0.039
|
|
|
|
midbrain development
|
GO:0030901 |
28 |
0.038
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
4 |
0.038
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
37 |
0.038
|
Human Mouse |
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
74 |
0.038
|
|
|
|
cellular protein modification process
|
GO:0006464 |
100 |
0.038
|
Human Mouse |
|
|
ectodermal placode development
|
GO:0071696 |
37 |
0.038
|
|
|
|
central nervous system myelination
|
GO:0022010 |
2 |
0.037
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
49 |
0.037
|
|
|
|
water homeostasis
|
GO:0030104 |
4 |
0.037
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
71 |
0.037
|
Human |
|
|
taxis
|
GO:0042330 |
109 |
0.036
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
156 |
0.036
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
15 |
0.036
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
94 |
0.036
|
|
|
|
regulation of response to stress
|
GO:0080134 |
36 |
0.036
|
Human |
|
|
endothelial cell development
|
GO:0001885 |
12 |
0.036
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.035
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.035
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.035
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
71 |
0.035
|
|
|
|
nuclear transport
|
GO:0051169 |
4 |
0.035
|
|
|
|
head development
|
GO:0060322 |
303 |
0.035
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
3 |
0.034
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
68 |
0.034
|
|
|
|
lens fiber cell development
|
GO:0070307 |
3 |
0.034
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
142 |
0.034
|
|
|
|
neural nucleus development
|
GO:0048857 |
15 |
0.034
|
|
|
|
activation of mapk activity
|
GO:0000187 |
3 |
0.034
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
231 |
0.033
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
56 |
0.033
|
Human Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
11 |
0.033
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
56 |
0.033
|
Human |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
2 |
0.033
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
55 |
0.032
|
Human |
|
|
forebrain regionalization
|
GO:0021871 |
4 |
0.032
|
|
|
|
single organism nuclear import
|
GO:1902593 |
3 |
0.032
|
|
|
|
sensory system development
|
GO:0048880 |
76 |
0.032
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
2 |
0.032
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
2 |
0.032
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
5 |
0.032
|
Human |
|
|
single organism localization
|
GO:1902578 |
225 |
0.032
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
59 |
0.032
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
2 |
0.032
|
|
|
|
aging
|
GO:0007568 |
2 |
0.032
|
|
|
|
axon guidance
|
GO:0007411 |
86 |
0.032
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
213 |
0.032
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
7 |
0.032
|
|
|
|
glial cell migration
|
GO:0008347 |
3 |
0.031
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
4 |
0.031
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
271 |
0.031
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
2 |
0.031
|
|
|
|
defense response to other organism
|
GO:0098542 |
33 |
0.031
|
|
|
|
cognition
|
GO:0050890 |
1 |
0.031
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
2 |
0.031
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
223 |
0.031
|
Human Mouse |
|
|
lateral line system development
|
GO:0048925 |
76 |
0.031
|
|
|
|
forebrain neuron fate commitment
|
GO:0021877 |
1 |
0.031
|
|
|
|
cell motility
|
GO:0048870 |
244 |
0.030
|
Human Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.030
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
3 |
0.030
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
30 |
0.030
|
|
|
|
cell cycle
|
GO:0007049 |
93 |
0.030
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
4 |
0.030
|
|
|
|
cell projection assembly
|
GO:0030031 |
64 |
0.030
|
Mouse Fly |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
125 |
0.030
|
|
|
|
detection of chemical stimulus
|
GO:0009593 |
4 |
0.030
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
3 |
0.030
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
4 |
0.030
|
|
|
|
phosphorylation
|
GO:0016310 |
69 |
0.030
|
Human Zebrafish Mouse |
|
|
intracellular signal transduction
|
GO:0035556 |
85 |
0.030
|
Human |
|
|
fin morphogenesis
|
GO:0033334 |
53 |
0.029
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
7 |
0.029
|
|
|
|
regulation of nitrogen compound metabolic process
|
GO:0051171 |
251 |
0.029
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
3 |
0.029
|
|
|
|
cilium assembly
|
GO:0042384 |
58 |
0.029
|
|
|
|
respiratory system development
|
GO:0060541 |
5 |
0.029
|
Mouse |
|
|
response to corticosteroid
|
GO:0031960 |
1 |
0.029
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.028
|
|
|
|
cellular protein metabolic process
|
GO:0044267 |
129 |
0.028
|
Human Mouse |
|
|
connective tissue development
|
GO:0061448 |
99 |
0.028
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
20 |
0.028
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
4 |
0.028
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
195 |
0.027
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
51 |
0.027
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
21 |
0.027
|
Human |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
15 |
0.027
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
3 |
0.027
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
2 |
0.027
|
|
|
|
renal system development
|
GO:0072001 |
94 |
0.026
|
Human Fly |
|
|
response to drug
|
GO:0042493 |
3 |
0.026
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
1 |
0.026
|
Human |
|
|
inner ear receptor cell fate commitment
|
GO:0060120 |
4 |
0.026
|
|
|
|
glucose homeostasis
|
GO:0042593 |
1 |
0.026
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
1 |
0.026
|
|
|
|
neural plate pattern specification
|
GO:0060896 |
12 |
0.026
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
2 |
0.026
|
|
|
|
cellular response to starvation
|
GO:0009267 |
1 |
0.026
|
|
|
|
ear morphogenesis
|
GO:0042471 |
64 |
0.025
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
4 |
0.025
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
1 |
0.025
|
|
|
|
inner ear development
|
GO:0048839 |
126 |
0.025
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
1 |
0.025
|
|
|
|
stem cell development
|
GO:0048864 |
82 |
0.025
|
|
|
|
phagocytosis
|
GO:0006909 |
3 |
0.025
|
|
|
|
negative regulation of metabolic process
|
GO:0009892 |
86 |
0.025
|
Human |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
3 |
0.025
|
|
|
|
negative regulation of leukocyte chemotaxis
|
GO:0002689 |
3 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
4 |
0.024
|
|
|
|
gland morphogenesis
|
GO:0022612 |
13 |
0.024
|
Mouse Fly |
|
|
cellular response to oxygen levels
|
GO:0071453 |
1 |
0.024
|
|
|
|
post embryonic morphogenesis
|
GO:0009886 |
4 |
0.024
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
9 |
0.024
|
Human |
|
|
gastrulation
|
GO:0007369 |
208 |
0.024
|
|
|
|
hair cell differentiation
|
GO:0035315 |
32 |
0.024
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
10 |
0.024
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
4 |
0.024
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
2 |
0.023
|
|
|
|
protein metabolic process
|
GO:0019538 |
183 |
0.023
|
Human Mouse |
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
8 |
0.023
|
|
|
|
nose development
|
GO:0043584 |
3 |
0.023
|
|
|
|
protein complex localization
|
GO:0031503 |
1 |
0.023
|
|
|
|
protein secretion
|
GO:0009306 |
1 |
0.023
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
28 |
0.023
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
3 |
0.023
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
3 |
0.023
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
26 |
0.023
|
Human Mouse |
|
|
cell death
|
GO:0008219 |
121 |
0.023
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
97 |
0.022
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
2 |
0.022
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
62 |
0.022
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
15 |
0.022
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
78 |
0.022
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
25 |
0.022
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
52 |
0.022
|
Mouse |
|
|
cellular response to stress
|
GO:0033554 |
62 |
0.022
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
62 |
0.022
|
|
|
|
regulation of cellular extravasation
|
GO:0002691 |
1 |
0.022
|
|
|
|
germ cell migration
|
GO:0008354 |
8 |
0.022
|
|
|
|
t cell activation
|
GO:0042110 |
6 |
0.022
|
|
|
|
aromatic compound biosynthetic process
|
GO:0019438 |
217 |
0.022
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
5 |
0.021
|
Human |
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
45 |
0.021
|
|
|
|
determination of pancreatic left right asymmetry
|
GO:0035469 |
11 |
0.021
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
98 |
0.021
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
63 |
0.021
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
57 |
0.021
|
Human |
|
|
dna metabolic process
|
GO:0006259 |
27 |
0.021
|
Human |
|
|
heart jogging
|
GO:0003146 |
40 |
0.021
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
96 |
0.021
|
|
|
|
response to stress
|
GO:0006950 |
263 |
0.021
|
Human |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
45 |
0.021
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
55 |
0.021
|
Human |
|
|
protein acylation
|
GO:0043543 |
3 |
0.021
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
30 |
0.020
|
|
|
|
organelle organization
|
GO:0006996 |
227 |
0.020
|
Mouse |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
59 |
0.020
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
2 |
0.020
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
57 |
0.020
|
|
|
|
exocrine system development
|
GO:0035272 |
28 |
0.020
|
Mouse Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
31 |
0.020
|
Human |
|
|
response to oxygen levels
|
GO:0070482 |
25 |
0.020
|
|
|
|
negative regulation of neutrophil chemotaxis
|
GO:0090024 |
3 |
0.020
|
|
|
|
programmed cell death
|
GO:0012501 |
119 |
0.020
|
|
|
|
determination of left right asymmetry in lateral mesoderm
|
GO:0003140 |
20 |
0.020
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
24 |
0.020
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
133 |
0.020
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
4 |
0.020
|
|
|
|
germ line stem cell division
|
GO:0042078 |
1 |
0.020
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
55 |
0.020
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
4 |
0.020
|
|
|
|
endoderm formation
|
GO:0001706 |
29 |
0.020
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
2 |
0.019
|
|
|
|
regulation of cardiac chamber morphogenesis
|
GO:1901219 |
2 |
0.019
|
|
|
|
establishment of endothelial barrier
|
GO:0061028 |
3 |
0.019
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
152 |
0.019
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.019
|
|
|
|
regulation of cell development
|
GO:0060284 |
100 |
0.019
|
|
|
|
nuclear import
|
GO:0051170 |
3 |
0.019
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
108 |
0.019
|
|
|
|
lymphatic endothelial cell fate commitment
|
GO:0060838 |
1 |
0.019
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
15 |
0.019
|
|
|
|
forebrain development
|
GO:0030900 |
96 |
0.019
|
|
|
|
mesoderm development
|
GO:0007498 |
88 |
0.018
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
163 |
0.018
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
1 |
0.018
|
|
|
|
myotube cell development
|
GO:0014904 |
35 |
0.018
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
35 |
0.018
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
2 |
0.018
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
22 |
0.018
|
Human |
|
|
defense response
|
GO:0006952 |
47 |
0.018
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
14 |
0.018
|
Human |
|
|
blood coagulation
|
GO:0007596 |
12 |
0.018
|
Human |
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
3 |
0.018
|
|
|
|
heart looping
|
GO:0001947 |
94 |
0.018
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
59 |
0.018
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
48 |
0.017
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
2 |
0.017
|
|
|
|
chemosensory behavior
|
GO:0007635 |
1 |
0.017
|
|
|
|
nerve development
|
GO:0021675 |
45 |
0.017
|
|
