Danio rerio

0 known processes

pdia5

protein disulfide isomerase family A, member 5

(Aliases: zgc:172235,wu:fb98h09,sb:cb441)

pdia5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
er to golgi vesicle mediated transport GO:0006888 1 0.353
golgi vesicle transport GO:0048193 3 0.248
apoptotic process GO:0006915 116 0.211
maintenance of location GO:0051235 4 0.194
synaptic growth at neuromuscular junction GO:0051124 2 0.191
regulation of establishment of protein localization GO:0070201 4 0.183
positive regulation of catabolic process GO:0009896 4 0.152
signal transduction GO:0007165 455 0.149
regulation of synapse assembly GO:0051963 3 0.147
localization within membrane GO:0051668 1 0.136
lipid storage GO:0019915 1 0.131
regulation of protein transport GO:0051223 3 0.125
regulation of metal ion transport GO:0010959 4 0.125
larval development GO:0002164 2 0.124
regulation of synapse organization GO:0050807 3 0.122
cell morphogenesis GO:0000902 289 0.119
response to organic substance GO:0010033 153 0.104
single organism metabolic process GO:0044710 217 0.103
nuclear transport GO:0051169 4 0.101
positive regulation of transport GO:0051050 2 0.101
sensory organ development GO:0007423 393 0.101
meiotic nuclear division GO:0007126 4 0.094
regulation of glucose transport GO:0010827 1 0.089
death GO:0016265 121 0.085
cell death GO:0008219 121 0.082
cognition GO:0050890 1 0.079
oxoacid metabolic process GO:0043436 31 0.077
regulation of cellular ketone metabolic process GO:0010565 7 0.077
locomotion GO:0040011 313 0.069
protein metabolic process GO:0019538 183 0.068
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.067
cellular amino acid metabolic process GO:0006520 7 0.065
regulation of nucleoside metabolic process GO:0009118 2 0.064
organonitrogen compound metabolic process GO:1901564 74 0.064
positive regulation of cellular component biogenesis GO:0044089 3 0.064
programmed cell death GO:0012501 119 0.063
digestive system development GO:0055123 289 0.062
meiotic cell cycle process GO:1903046 3 0.060
central nervous system development GO:0007417 387 0.060
chromosome organization involved in meiosis GO:0070192 1 0.059
response to chemical GO:0042221 320 0.057
organic substance biosynthetic process GO:1901576 289 0.056
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.056
positive regulation of cellular catabolic process GO:0031331 3 0.056
nucleocytoplasmic transport GO:0006913 4 0.056
single organism localization GO:1902578 225 0.054
establishment of protein localization to organelle GO:0072594 4 0.054
establishment of localization in cell GO:0051649 77 0.052
nucleic acid metabolic process GO:0090304 244 0.052
cell substrate junction assembly GO:0007044 2 0.052
adult behavior GO:0030534 2 0.051
eye development GO:0001654 277 0.051
cell motility GO:0048870 244 0.050
single organism transport GO:0044765 206 0.048
phagocytosis GO:0006909 3 0.048
ion transmembrane transport GO:0034220 91 0.047
multicellular organism growth GO:0035264 4 0.046
autophagy GO:0006914 4 0.045
negative regulation of cellular process GO:0048523 283 0.044
response to stress GO:0006950 263 0.043
regulation of intracellular protein transport GO:0033157 3 0.043
regulation of localization GO:0032879 104 0.042
cell cycle GO:0007049 93 0.042
glucose homeostasis GO:0042593 1 0.041
macromolecule biosynthetic process GO:0009059 227 0.041
protein import into nucleus GO:0006606 3 0.040
glucose import GO:0046323 2 0.039
amine metabolic process GO:0009308 2 0.039
negative regulation of cell differentiation GO:0045596 46 0.039
biosynthetic process GO:0009058 294 0.039
single organism cellular localization GO:1902580 46 0.039
cellular response to stress GO:0033554 62 0.039
regulation of cytoplasmic transport GO:1903649 4 0.038
regulation of macromolecule metabolic process GO:0060255 317 0.038
regulation of ion transmembrane transporter activity GO:0032412 2 0.038
single organism biosynthetic process GO:0044711 71 0.037
cellular response to organic substance GO:0071310 105 0.037
cellular ketone metabolic process GO:0042180 11 0.037
cellular carbohydrate metabolic process GO:0044262 4 0.037
digestive tract morphogenesis GO:0048546 231 0.036
regulation of sodium ion transport GO:0002028 2 0.035
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.035
carboxylic acid metabolic process GO:0019752 22 0.034
regulation of transcription dna templated GO:0006355 213 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.034
developmental growth involved in morphogenesis GO:0060560 86 0.034
modification dependent protein catabolic process GO:0019941 3 0.033
protein targeting to nucleus GO:0044744 3 0.033
regulation of developmental process GO:0050793 247 0.033
stem cell maintenance GO:0019827 4 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
regulation of protein targeting GO:1903533 2 0.032
cytokinesis GO:0000910 3 0.031
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
neuron differentiation GO:0030182 353 0.031
regulation of nucleotide catabolic process GO:0030811 2 0.031
cellular protein modification process GO:0006464 100 0.031
cell projection organization GO:0030030 284 0.031
adherens junction organization GO:0034332 4 0.030
cellular protein catabolic process GO:0044257 4 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
regulation of gtpase activity GO:0043087 2 0.030
protein n linked glycosylation GO:0006487 1 0.030
regulation of protein catabolic process GO:0042176 1 0.029
regulation of transmembrane transport GO:0034762 18 0.029
cellular protein metabolic process GO:0044267 129 0.029
regulation of cell substrate adhesion GO:0010810 1 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.029
positive regulation of nucleoside metabolic process GO:0045979 1 0.029
organic acid metabolic process GO:0006082 31 0.028
cellular macromolecule metabolic process GO:0044260 391 0.028
transmembrane transport GO:0055085 120 0.028
cellular biosynthetic process GO:0044249 286 0.028
regulation of nervous system development GO:0051960 90 0.028
protein import GO:0017038 3 0.028
positive regulation of cellular process GO:0048522 201 0.028
guanosine containing compound metabolic process GO:1901068 4 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
regulation of multicellular organismal development GO:2000026 223 0.027
metal ion transport GO:0030001 58 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
single organism nuclear import GO:1902593 3 0.027
nuclear import GO:0051170 3 0.027
cellular component maintenance GO:0043954 3 0.027
positive regulation of macromolecule metabolic process GO:0010604 93 0.027
cell part morphogenesis GO:0032990 246 0.026
single organism organelle organization GO:1902589 199 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
regulation of glucose import GO:0046324 1 0.026
pigmentation GO:0043473 85 0.026
glycoprotein biosynthetic process GO:0009101 21 0.026
regulation of biosynthetic process GO:0009889 250 0.026
rna 3 end processing GO:0031123 2 0.026
proteasomal protein catabolic process GO:0010498 2 0.026
aging GO:0007568 2 0.026
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
protein localization to plasma membrane GO:0072659 1 0.025
positive regulation of biosynthetic process GO:0009891 68 0.025
positive regulation of synapse assembly GO:0051965 1 0.025
protein localization to nucleus GO:0034504 3 0.025
regulation of reproductive process GO:2000241 4 0.025
behavior GO:0007610 74 0.025
regulation of cell shape GO:0008360 1 0.025
activation of mapk activity GO:0000187 3 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
morphogenesis of an epithelium GO:0002009 333 0.024
negative regulation of catabolic process GO:0009895 3 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
cellular response to organic cyclic compound GO:0071407 38 0.024
response to oxygen containing compound GO:1901700 55 0.024
coenzyme biosynthetic process GO:0009108 2 0.024
cell junction maintenance GO:0034331 2 0.024
positive regulation of metabolic process GO:0009893 108 0.024
sprouting angiogenesis GO:0002040 53 0.024
fatty acid beta oxidation GO:0006635 1 0.024
tube morphogenesis GO:0035239 349 0.023
regulation of hydrolase activity GO:0051336 28 0.023
immune system process GO:0002376 241 0.022
negative regulation of developmental process GO:0051093 65 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of cell communication GO:0010646 232 0.022
peptidyl serine modification GO:0018209 2 0.022
regulation of cell differentiation GO:0045595 142 0.022
intracellular transport GO:0046907 32 0.022
negative regulation of rna splicing GO:0033119 1 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.022
er nucleus signaling pathway GO:0006984 2 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
negative regulation of cell communication GO:0010648 96 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
regulation of carbohydrate biosynthetic process GO:0043255 1 0.021
cellular amine metabolic process GO:0044106 2 0.021
glycoprotein metabolic process GO:0009100 23 0.020
cellular component assembly GO:0022607 170 0.020
medulla oblongata development GO:0021550 4 0.020
cellular response to endogenous stimulus GO:0071495 68 0.020
protein dephosphorylation GO:0006470 3 0.020
regulation of protein complex assembly GO:0043254 3 0.020
immune response activating signal transduction GO:0002757 5 0.020
protein stabilization GO:0050821 2 0.020
lipid oxidation GO:0034440 1 0.020
chordate embryonic development GO:0043009 271 0.019
positive regulation of cell death GO:0010942 29 0.019
rna localization GO:0006403 4 0.019
cell migration GO:0016477 237 0.019
mononuclear cell proliferation GO:0032943 1 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.019
chemosensory behavior GO:0007635 1 0.018
germ line stem cell division GO:0042078 1 0.018
head development GO:0060322 303 0.018
sensory organ morphogenesis GO:0090596 200 0.018
alpha amino acid metabolic process GO:1901605 3 0.018
negative regulation of cellular catabolic process GO:0031330 3 0.018
positive regulation of apoptotic process GO:0043065 29 0.018
response to estrogen GO:0043627 27 0.018
cellular modified amino acid metabolic process GO:0006575 3 0.018
positive regulation of cell cycle GO:0045787 3 0.018
generation of neurons GO:0048699 385 0.018
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.018
gtp catabolic process GO:0006184 2 0.018
positive regulation of glucose import GO:0046326 1 0.018
nucleic acid transport GO:0050657 2 0.017
regulation of dna replication GO:0006275 3 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
negative regulation of cytoplasmic transport GO:1903650 2 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
toxin transport GO:1901998 2 0.017
organelle localization GO:0051640 49 0.017
sodium ion transport GO:0006814 24 0.017
mitotic cell cycle GO:0000278 64 0.017
cellular component movement GO:0006928 335 0.017
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of gtp catabolic process GO:0033124 2 0.016
negative regulation of biological process GO:0048519 304 0.016
regulation of stem cell differentiation GO:2000736 4 0.016
cellular component morphogenesis GO:0032989 336 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
cell growth GO:0016049 57 0.016
proteoglycan metabolic process GO:0006029 14 0.016
hormone transport GO:0009914 2 0.016
positive regulation of gene expression GO:0010628 71 0.016
regulation of biological quality GO:0065008 263 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
energy homeostasis GO:0097009 3 0.016
positive regulation of rna biosynthetic process GO:1902680 57 0.016
camera type eye morphogenesis GO:0048593 108 0.016
system process GO:0003008 185 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
regulation of dna templated transcription elongation GO:0032784 3 0.015
adherens junction maintenance GO:0034334 2 0.015
positive regulation of carbohydrate metabolic process GO:0045913 1 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
regulation of developmental growth GO:0048638 38 0.015
mesenchyme development GO:0060485 127 0.015
cell projection morphogenesis GO:0048858 244 0.015
erythrocyte homeostasis GO:0034101 55 0.015
negative regulation of signal transduction GO:0009968 94 0.015
positive regulation of immune response GO:0050778 11 0.015
embryonic organ development GO:0048568 381 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
carbohydrate homeostasis GO:0033500 1 0.015
zinc ion transport GO:0006829 2 0.015
organelle organization GO:0006996 227 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
regulation of neuron differentiation GO:0045664 56 0.014
transport GO:0006810 220 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
cell cycle arrest GO:0007050 1 0.014
regulation of transporter activity GO:0032409 2 0.014
extracellular structure organization GO:0043062 27 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
glycerophospholipid biosynthetic process GO:0046474 1 0.014
regulation of blood vessel size GO:0050880 2 0.014
positive regulation of nervous system development GO:0051962 25 0.014
convergent extension GO:0060026 118 0.014
cytoplasmic transport GO:0016482 11 0.014
heterocycle metabolic process GO:0046483 290 0.014
regulation of signaling GO:0023051 235 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
cellular response to estrogen stimulus GO:0071391 24 0.014
synaptic vesicle recycling GO:0036465 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
lipid homeostasis GO:0055088 3 0.014
brain development GO:0007420 293 0.014
digestive tract development GO:0048565 265 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
multicellular organismal metabolic process GO:0044236 2 0.013
regulation of locomotion GO:0040012 55 0.013
regulation of autophagy GO:0010506 3 0.013
establishment of localization GO:0051234 244 0.013
gene expression GO:0010467 252 0.013
tube formation GO:0035148 25 0.013
response to metal ion GO:0010038 34 0.013
cellular localization GO:0051641 97 0.013
sister chromatid cohesion GO:0007062 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
protein modification process GO:0036211 100 0.013
negative regulation of tor signaling GO:0032007 2 0.013
catabolic process GO:0009056 32 0.013
germ line stem cell maintenance GO:0030718 2 0.013
nucleobase containing compound transport GO:0015931 2 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
cellular sodium ion homeostasis GO:0006883 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
organism emergence from protective structure GO:0071684 4 0.013
long chain fatty acid metabolic process GO:0001676 1 0.012
response to hexose GO:0009746 3 0.012
response to amino acid GO:0043200 2 0.012
lymphocyte proliferation GO:0046651 1 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
nucleic acid templated transcription GO:0097659 181 0.012
cellular response to lipid GO:0071396 39 0.012
glucose transport GO:0015758 6 0.012
glycerolipid biosynthetic process GO:0045017 1 0.012
otolith development GO:0048840 32 0.012
regulation of transport GO:0051049 45 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
regulation of cell activation GO:0050865 1 0.012
cation transmembrane transport GO:0098655 65 0.012
small molecule metabolic process GO:0044281 77 0.012
response to vitamin GO:0033273 3 0.012
carbohydrate transport GO:0008643 13 0.012
rna biosynthetic process GO:0032774 181 0.012
cellular response to hormone stimulus GO:0032870 39 0.012
golgi organization GO:0007030 1 0.012
regulation of neurogenesis GO:0050767 87 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
determination of left right symmetry GO:0007368 179 0.011
regulation of calcium ion transport GO:0051924 2 0.011
growth GO:0040007 174 0.011
chondroitin sulfate proteoglycan metabolic process GO:0050654 8 0.011
cofactor biosynthetic process GO:0051188 10 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
neuromuscular junction development GO:0007528 9 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
locomotor rhythm GO:0045475 3 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
tissue remodeling GO:0048771 4 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
lipid catabolic process GO:0016042 4 0.011
epidermis morphogenesis GO:0048730 4 0.011
myeloid cell homeostasis GO:0002262 56 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
organic substance transport GO:0071702 58 0.011
single organism intracellular transport GO:1902582 25 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
regulation of primary metabolic process GO:0080090 311 0.011
neuromast deposition GO:0048885 9 0.011
macromolecule localization GO:0033036 54 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
hatching GO:0035188 4 0.011
regulation of molecular function GO:0065009 70 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
cellular response to external stimulus GO:0071496 2 0.011
cellular response to starvation GO:0009267 1 0.010
positive regulation of map kinase activity GO:0043406 3 0.010
hydrogen peroxide metabolic process GO:0042743 2 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
response to inorganic substance GO:0010035 38 0.010
extracellular matrix organization GO:0030198 27 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
g2 dna damage checkpoint GO:0031572 3 0.010
double strand break repair GO:0006302 3 0.010

pdia5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.039
disease of cellular proliferation DOID:14566 0 0.039
organ system cancer DOID:0050686 0 0.039
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.020
x linked disease DOID:0050735 0 0.018
myopathy DOID:423 0 0.015
muscular disease DOID:0080000 0 0.015
musculoskeletal system disease DOID:17 0 0.015
muscle tissue disease DOID:66 0 0.015
connective tissue disease DOID:65 0 0.015
immune system disease DOID:2914 0 0.014
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010