Danio rerio

0 known processes

cpe

carboxypeptidase E

(Aliases: si:ch211-198g9.2,zgc:85981)

cpe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
guanosine containing compound metabolic process GO:1901068 4 0.133
cognition GO:0050890 1 0.132
embryonic organ development GO:0048568 381 0.132
regulation of gtp catabolic process GO:0033124 2 0.118
multicellular organism growth GO:0035264 4 0.105
regulation of multicellular organism growth GO:0040014 4 0.093
signal transduction GO:0007165 455 0.086
regulation of response to stimulus GO:0048583 269 0.077
chemosensory behavior GO:0007635 1 0.075
meiotic nuclear division GO:0007126 4 0.069
neurotransmitter secretion GO:0007269 2 0.066
Worm
ion transmembrane transport GO:0034220 91 0.062
response to external stimulus GO:0009605 264 0.061
regulation of nucleotide catabolic process GO:0030811 2 0.059
regulation of nucleoside metabolic process GO:0009118 2 0.056
positive regulation of protein complex assembly GO:0031334 2 0.056
gtp catabolic process GO:0006184 2 0.055
single organism transport GO:0044765 206 0.054
Worm
synaptic growth at neuromuscular junction GO:0051124 2 0.052
response to chemical GO:0042221 320 0.048
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.047
aging GO:0007568 2 0.046
guanosine containing compound catabolic process GO:1901069 2 0.046
g protein coupled receptor signaling pathway GO:0007186 74 0.046
regulation of purine nucleotide catabolic process GO:0033121 2 0.045
regulation of reproductive process GO:2000241 4 0.045
gtp metabolic process GO:0046039 4 0.044
transmembrane transport GO:0055085 120 0.044
lipid storage GO:0019915 1 0.043
localization of cell GO:0051674 244 0.043
establishment of localization GO:0051234 244 0.043
Worm
heterocycle metabolic process GO:0046483 290 0.042
regulation of protein complex assembly GO:0043254 3 0.042
somatic muscle development GO:0007525 4 0.041
small molecule metabolic process GO:0044281 77 0.041
cellular response to external stimulus GO:0071496 2 0.041
cellular component movement GO:0006928 335 0.040
regulation of purine nucleotide metabolic process GO:1900542 17 0.040
regulation of signaling GO:0023051 235 0.040
response to abiotic stimulus GO:0009628 122 0.039
inorganic ion transmembrane transport GO:0098660 57 0.039
regulation of metabolic process GO:0019222 359 0.039
larval development GO:0002164 2 0.038
positive regulation of biological process GO:0048518 253 0.038
cell motility GO:0048870 244 0.037
organelle organization GO:0006996 227 0.036
positive regulation of secretion by cell GO:1903532 1 0.035
regulation of hydrolase activity GO:0051336 28 0.035
response to external biotic stimulus GO:0043207 97 0.034
negative regulation of cellular process GO:0048523 283 0.034
regulation of cell communication GO:0010646 232 0.034
single organism organelle organization GO:1902589 199 0.034
meiotic cell cycle process GO:1903046 3 0.033
cell growth GO:0016049 57 0.033
regulation of ion transmembrane transporter activity GO:0032412 2 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
Mouse
cellular response to nutrient levels GO:0031669 2 0.033
regulation of filopodium assembly GO:0051489 2 0.033
response to glucose GO:0009749 3 0.032
locomotion GO:0040011 313 0.032
positive regulation of catabolic process GO:0009896 4 0.032
regulation of signal transduction GO:0009966 225 0.031
regulation of cell projection assembly GO:0060491 4 0.031
cellular response to extracellular stimulus GO:0031668 2 0.031
amine metabolic process GO:0009308 2 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.030
regulation of gtpase activity GO:0043087 2 0.030
organic cyclic compound metabolic process GO:1901360 301 0.030
inorganic cation transmembrane transport GO:0098662 50 0.030
regulation of synaptic plasticity GO:0048167 1 0.029
neurotransmitter transport GO:0006836 2 0.029
Worm
cell cycle g2 m phase transition GO:0044839 4 0.029
single organism metabolic process GO:0044710 217 0.029
negative regulation of protein complex assembly GO:0031333 1 0.029
regulation of developmental process GO:0050793 247 0.028
nitrogen compound metabolic process GO:0006807 319 0.028
Mouse
ion transport GO:0006811 114 0.028
Worm
maintenance of location GO:0051235 4 0.028
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
cell projection organization GO:0030030 284 0.027
regulation of neuronal synaptic plasticity GO:0048168 1 0.027
phosphate containing compound metabolic process GO:0006796 108 0.027
carbohydrate derivative metabolic process GO:1901135 61 0.026
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
nuclear migration GO:0007097 3 0.026
regulation of hormone secretion GO:0046883 2 0.026
fertilization GO:0009566 3 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.025
cellular amine metabolic process GO:0044106 2 0.025
sensory organ development GO:0007423 393 0.025
small gtpase mediated signal transduction GO:0007264 8 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.025
cell migration GO:0016477 237 0.025
positive regulation of transport GO:0051050 2 0.025
regulation of endocrine process GO:0044060 2 0.024
protein localization to nucleus GO:0034504 3 0.024
mitochondrion organization GO:0007005 4 0.024
regulation of cellular ph GO:0030641 1 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
cell death GO:0008219 121 0.023
negative regulation of catabolic process GO:0009895 3 0.023
regulation of cytokine production GO:0001817 3 0.023
positive regulation of cellular process GO:0048522 201 0.022
sensory system development GO:0048880 76 0.022
positive regulation of gtpase activity GO:0043547 1 0.022
regulation of transporter activity GO:0032409 2 0.022
cell part morphogenesis GO:0032990 246 0.022
tube morphogenesis GO:0035239 349 0.022
negative regulation of biological process GO:0048519 304 0.022
camera type eye development GO:0043010 222 0.022
membrane fusion GO:0061025 2 0.022
positive regulation of translation GO:0045727 1 0.021
stem cell proliferation GO:0072089 4 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
oocyte maturation GO:0001556 4 0.021
hatching GO:0035188 4 0.021
negative regulation of intracellular protein transport GO:0090317 3 0.021
positive regulation of gtp catabolic process GO:0033126 1 0.021
cellular response to radiation GO:0071478 4 0.021
nerve development GO:0021675 45 0.021
cellular localization GO:0051641 97 0.021
Human Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.020
response to monosaccharide GO:0034284 3 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
peripheral nervous system neuron axonogenesis GO:0048936 13 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
regulation of protein polymerization GO:0032271 2 0.020
heart development GO:0007507 313 0.019
Human
regulation of cellular metabolic process GO:0031323 320 0.019
regulation of binding GO:0051098 3 0.019
system process GO:0003008 185 0.019
negative regulation of metabolic process GO:0009892 86 0.019
response to light stimulus GO:0009416 46 0.019
regulation of synapse assembly GO:0051963 3 0.019
ras protein signal transduction GO:0007265 7 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
Mouse
negative regulation of cellular catabolic process GO:0031330 3 0.019
response to radiation GO:0009314 51 0.019
lateral line system development GO:0048925 76 0.019
positive regulation of protein polymerization GO:0032273 2 0.019
eye development GO:0001654 277 0.018
gene expression GO:0010467 252 0.018
Mouse Worm
response to carbohydrate GO:0009743 3 0.018
regulation of protein catabolic process GO:0042176 1 0.018
endocrine process GO:0050886 2 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
regulation of protein targeting GO:1903533 2 0.018
adult behavior GO:0030534 2 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
phagocytosis engulfment GO:0006911 1 0.018
regulation of localization GO:0032879 104 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
chemotaxis GO:0006935 104 0.017
cellular response to organic cyclic compound GO:0071407 38 0.017
Zebrafish
single fertilization GO:0007338 3 0.017
single organism membrane fusion GO:0044801 2 0.017
regulation of metal ion transport GO:0010959 4 0.017
cell morphogenesis GO:0000902 289 0.017
er to golgi vesicle mediated transport GO:0006888 1 0.017
response to other organism GO:0051707 97 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
regulation of primary metabolic process GO:0080090 311 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of blood pressure GO:0008217 1 0.017
response to topologically incorrect protein GO:0035966 2 0.017
synaptic vesicle transport GO:0048489 1 0.017
response to drug GO:0042493 3 0.017
negative regulation of intracellular transport GO:0032387 3 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
neuron development GO:0048666 262 0.017
embryonic heart tube development GO:0035050 133 0.016
organic acid metabolic process GO:0006082 31 0.016
regulation of catalytic activity GO:0050790 55 0.016
cation transmembrane transport GO:0098655 65 0.016
ribosomal small subunit biogenesis GO:0042274 2 0.016
cellular ketone metabolic process GO:0042180 11 0.016
cellular response to organic substance GO:0071310 105 0.016
Zebrafish
oxoacid metabolic process GO:0043436 31 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
lateral line development GO:0048882 66 0.016
synaptic vesicle localization GO:0097479 1 0.016
response to organic substance GO:0010033 153 0.016
Zebrafish
protein dephosphorylation GO:0006470 3 0.016
cellular response to starvation GO:0009267 1 0.016
axon development GO:0061564 166 0.016
single organism reproductive process GO:0044702 40 0.016
regulation of intracellular protein transport GO:0033157 3 0.015
microtubule polymerization or depolymerization GO:0031109 3 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
actin filament polymerization GO:0030041 2 0.015
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of molecular function GO:0065009 70 0.015
sleep GO:0030431 1 0.015
digestive tract morphogenesis GO:0048546 231 0.015
positive regulation of gene expression GO:0010628 71 0.015
generation of neurons GO:0048699 385 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
atp catabolic process GO:0006200 4 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
response to stress GO:0006950 263 0.015
regulation of gene expression GO:0010468 265 0.015
nuclear transport GO:0051169 4 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of biological quality GO:0065008 263 0.015
Mouse Worm
organic substance biosynthetic process GO:1901576 289 0.015
endocrine hormone secretion GO:0060986 2 0.015
taxis GO:0042330 109 0.015
cell projection morphogenesis GO:0048858 244 0.015
neurological system process GO:0050877 62 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
peptidyl threonine phosphorylation GO:0018107 1 0.014
single organism behavior GO:0044708 24 0.014
embryonic skeletal system development GO:0048706 97 0.014
single organism localization GO:1902578 225 0.014
Human Worm
regulation of ph GO:0006885 3 0.014
egg activation GO:0007343 1 0.014
apoptotic process GO:0006915 116 0.014
response to hexose GO:0009746 3 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
organelle fusion GO:0048284 3 0.014
negative regulation of protein transport GO:0051224 3 0.014
protein polymerization GO:0051258 4 0.014
neuroblast proliferation GO:0007405 2 0.014
positive regulation of ras protein signal transduction GO:0046579 1 0.014
negative regulation of kinase activity GO:0033673 4 0.014
regulation of cell activation GO:0050865 1 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
protein import into nucleus GO:0006606 3 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
cation transport GO:0006812 81 0.014
Worm
inner ear development GO:0048839 126 0.014
cranial nerve development GO:0021545 42 0.013
intracellular signal transduction GO:0035556 85 0.013
regulation of sodium ion transport GO:0002028 2 0.013
optic nerve development GO:0021554 15 0.013
neuron differentiation GO:0030182 353 0.013
retina homeostasis GO:0001895 12 0.013
heart morphogenesis GO:0003007 156 0.013
Human
exocytosis GO:0006887 1 0.013
female meiotic division GO:0007143 2 0.013
peptidyl serine modification GO:0018209 2 0.013
neuron projection morphogenesis GO:0048812 161 0.013
brain development GO:0007420 293 0.013
organophosphate metabolic process GO:0019637 37 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
rna localization GO:0006403 4 0.013
ribonucleotide metabolic process GO:0009259 27 0.013
signal transduction in absence of ligand GO:0038034 1 0.013
amino acid transport GO:0006865 2 0.013
hormone transport GO:0009914 2 0.012
protein import GO:0017038 3 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
endosomal transport GO:0016197 2 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
mechanosensory lateral line system development GO:0048881 49 0.012
mechanosensory behavior GO:0007638 2 0.012
monovalent inorganic cation transport GO:0015672 42 0.012
nonmotile primary cilium assembly GO:0035058 2 0.012
hormone secretion GO:0046879 2 0.012
water homeostasis GO:0030104 4 0.012
multi organism process GO:0051704 134 0.012
regulation of oocyte development GO:0060281 3 0.012
peptidyl threonine modification GO:0018210 1 0.012
cellular biogenic amine metabolic process GO:0006576 2 0.012
wnt signaling pathway GO:0016055 80 0.012
regulation of muscle contraction GO:0006937 3 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.012
protein targeting to nucleus GO:0044744 3 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
Zebrafish
regulation of tube size GO:0035150 2 0.012
activation of mapk activity GO:0000187 3 0.012
peripheral nervous system neuron development GO:0048935 22 0.012
regulation of intracellular ph GO:0051453 1 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
programmed cell death GO:0012501 119 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
protein complex disassembly GO:0043241 1 0.011
positive regulation of cell activation GO:0050867 1 0.011
chemical homeostasis GO:0048878 49 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
golgi vesicle transport GO:0048193 3 0.011
negative regulation of molecular function GO:0044092 23 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
tissue homeostasis GO:0001894 25 0.011
single organism nuclear import GO:1902593 3 0.011
actin filament based movement GO:0030048 1 0.011
ameboidal type cell migration GO:0001667 143 0.011
digestive system development GO:0055123 289 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
phototransduction GO:0007602 2 0.011
cellular component disassembly GO:0022411 1 0.011
developmental growth GO:0048589 166 0.011
blood vessel development GO:0001568 246 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
regulation of protein binding GO:0043393 3 0.011
protein localization GO:0008104 40 0.011
Human
regulation of wound healing GO:0061041 2 0.011
protein metabolic process GO:0019538 183 0.011
Mouse Worm
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
lamellipodium organization GO:0097581 1 0.011
growth GO:0040007 174 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
phagocytosis GO:0006909 3 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
energy reserve metabolic process GO:0006112 2 0.010
cellular macromolecule metabolic process GO:0044260 391 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
cytokinesis GO:0000910 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to unfolded protein GO:0006986 2 0.010
behavior GO:0007610 74 0.010
purine containing compound metabolic process GO:0072521 29 0.010
macromolecule localization GO:0033036 54 0.010
Human
rna 3 end processing GO:0031123 2 0.010
positive regulation of exocytosis GO:0045921 1 0.010
response to alkaloid GO:0043279 2 0.010
stem cell maintenance GO:0019827 4 0.010
cellular protein complex assembly GO:0043623 19 0.010
protein modification process GO:0036211 100 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
purine ribonucleotide metabolic process GO:0009150 27 0.010
response to corticosteroid GO:0031960 1 0.010
dicarboxylic acid transport GO:0006835 1 0.010
lateral inhibition GO:0046331 1 0.010

cpe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
disease of metabolism DOID:0014667 0 0.014
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
nervous system disease DOID:863 0 0.013
disease of mental health DOID:150 0 0.010